http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
만성활동성 간염과 간경변증 환자에서 혈청 4형 교원질의 의의
이양일(Yang Il Lee),최성곤(Seong Kon Choi),금민수(Min Soo Keum),김영탁(Young Tak Kim),권혁만(Hyeok Man Kweon),김대현(Dae Hyun Kim),최영환(Young Hwan Choi),김성국(Sung Kook Kim),권영오(Young Oh Kweon),최용환(Yong Hwan Choi),정준모(Joo 대한소화기학회 1997 대한소화기학회지 Vol.29 No.1
N/A Background/Aims: Liver biosy is usually used to assess the expect of hepatic fibrosis, however, it is limited hecause serious complications have been reperted accasionally and frequent examinations are not adequate, Recently, the serum level of type IV collagen-7S domain is known to reflect the activity of collagen synthesis in the process of fibrosis. We evaluate the clinical usefulness of serum type IV collagen as an indicator of hepatic fibrosis. Methods: Serurn levels of type IV collagen 7S domain were evaluated in 88 subjects including 20 healthy persons, 40 patients with chronic active hepatitis confirmed by liver biopsy and 28 patients with liver cirrhosis. The patients with chronic active hepatitis were classified as mild(18 cases), moderate(11 cases) and severe degree(11 cases) according to the histologic findings and the patients with liver cirrhosis were classified as Child A(10 cases), B(10 cases), C(8 cases) according to modified Childs classification. Serum level of type IV collagen-7S domain was measured by radioimmunoassay (RJA). Results: Serum type IV collagen-7S domain concentrations in patients with chronic active hepatitis and liver cirrhosis were significantly higher than those in healthy persons(p<0.05). And significant correlations between the patients with chronic active hepatitis and with liver cirrhosis were also found(p<0.05). When chronic active hepatitis was divided into mild, moderate and severe degree there was a statistical significances(p<0.05). And significant correlations were found between the serum type IV collagen and the grade of the modified Childs classification(p<0.05). Conclusions: These results suggest that the measurement of serum type IV co]lagen may be a simple, noninvasive method and sensitive rnarker of hepatic fibrosis and also may reflect tbe status of progression in cirrhosis. (Korean J Gastroenterol 1997; 29:65 - 73)
간경변증환자에 있어서 초음파를 이용한 신혈류 저항계수 측정의 의의
이양일(Yang Il Lee),최성곤(Sung Kon Choi),김영탁(Young Tak Kim),금민수(Min Soo Keum),권영오(Yong Oh Kweon),최용환(Yong Hwan Choi),정준모(Jun Mo Jung) 대한내과학회 1996 대한내과학회지 Vol.50 No.3
N/A Objectives: Advanced liver cirrhosis commonly complicated hepatorenal syndrome, which is functional renal failure and the most extreme manifestation of systemic hemodynamic derangement resulting from impaired renal perfusion associated with portal hypertension and ascites. Selective nenal angiograms show marked beading and tortuosity of the inter-lobar and proximal arcuate arteries and a lack of distinct cortex and vascular filling of the cortical vessels. The aim of this study is to evaluate whether Duplex US can allow detection of intrarenal abnormal vascular impedance in patients with liver cirrhosis, even in the absence of an elevated serum creatinine value and full-blown hepatorenal syndrome. Methods: Duplex Doppler Ultrasonography allows noninvasive evaluation of intrarenal arterial resistances. In 8 nonascitic and 18 ascitic cirrhotic patients with normal renal function test(normal serum creatinine and urea levels) and in 10 normal controls, we neasurd the intrarenal arterial resistive index(Resistive index = [peak systolic velocity Minimum diastolic velocityl] /Peak systolic velocity) by Duplex Doppler US after visualization of interlobar or interlobular arteries by color Doppler US. Results: The resistive index was significantly higher in cirrhotic patients than in control patients(resistive index: 0.67±0.065 vs. 0.56±0.007, p<0.001). The resistive index was significantly higher in nonascitic cirrhotic patients than in control patients, in ascitic patients than in nonascitic patients, and in Child-Turcotte-Pugh class C patients than in class A, B patients. Thus renal arterial resistive index evaluated by Duplex Doppler US was already increased in the nonascitic phase of cirrhosis and was greater in the ascitic phase, Vasoconstriction was also related to the severity of liver disease as evaluated with Child-Turcotte-Pugh criteria. Conclusion: Duplex US of intraparenchymal renal arteries is a simple, noninvasive method to detect even subtle derangements in renal hemodynamics in liver cirrhosis and can be useful for identification of patients with higher risk of overt renal failure and to guide the therapeutic approach(paracentesis, diuretics).
이시온(Sion Lee),한준희(Junhee Han),손민균(Min Kyun Sohn),이종민(Jongmin Lee),김덕용(Deog Young Kim),신용일(Yong-Il Shin),오경재(Gyung-Jae Oh),이양수(Yang-Soo Lee),주민철(Min Cheol Joo),이소영(So Young Lee),송민근(Min-Keun Song),안정훈( 한국자료분석학회 2023 Journal of the Korean Data Analysis Society Vol.25 No.3
뇌졸중이란 뇌혈류 차단으로 산소와 영양공급이 막혀 뇌조직 일부의 손상이 초래되는 질병이다. 뇌졸중에 의한 사망률은 감소하는 추세지만 후유장애, 특히 기능장애로 불편함을 호소하는 환자는 늘어나고 있다. 그러나 뇌졸중 환자를 대상으로 한 연구만 지속될 뿐, 재발 환자를 포함하지 않은 초발 뇌졸중 환자를 대상으로 한 연구는 아직 부족한 실정이다. 이에 본 연구는 한국판 수정 바델 지수(K-MBI)라 불리는 재활 분야에서 흔하게 사용하는 뇌졸중 환자의 일상생활활동 평가 도구를 기능점수의 기준으로 사용해 초발 뇌졸중 기능에 영향을 미치는 요인을 규명하고 궁극적으로 보건의료 정책에 도움을 주고자 했다. 본 연구에서 사용된 자료는 각 개체에 대한 반복적인 측정값으로 이루어진 종단자료로 상관성을 고려하는 분석 방법이 필요해 다수준 분석을 시행하였다. 일반화 추정 방정식 모형(GEE)으로는 모든 변수가 유의하게 나왔지만 다수준 모형은 배우자 유무(미혼보다 기혼), 입원 기간(짧을수록), 나이(적을수록)에 따라 기능점수 회복이 유의미했다(p-value<0.05). 또한, 초기 뇌졸중 중증도에 따른 기능점수의 차이가 있음을 확인했다. 따라서 본 연구는 초발 뇌졸중 환자의 기능향상을 위해서 초기 뇌졸중 중증도에 따라 다른 의료적 접근의 필요성을 제시한다는 점에서 의의가 있다. Stroke is a disease in which oxygen and nutrition are blocked by blocking cerebral blood flow, causing damage to some of the brain tissue. The mortality rate from stroke is decreasing, but the number of patients complaining of discomfort due to aftereffects, especially dysfunction, is increasing. However, only studies on stroke patients continue, and studies on initial stroke patients that do not include recurrence patients are still insufficient. Accordingly, this study tried to identify factors affecting initial stroke function and ultimately help health care policies by using a tool for evaluating daily life activities of stroke patients commonly used in the rehabilitation field called the Korean version of the K-MBI. The data used in this study is longitudinal data consisting of repeated measurements for each object, and a multi-level analysis was conducted because an analysis method that considers correlation was needed. All variables were significant in the generalized estimation equation model (GEE), but the majority model showed significant functional score recovery depending on the presence of a spouse (married than unmarried), hospitalization period (shorter), and age (less); p-value<0.05. In addition, it was confirmed that there was a difference in function scores according to the severity of the initial stroke. Therefore, this study is meaningful in that it presents the need for a different medical approach depending on the severity of the initial stroke to improve the function of patients with initial stroke.
식육중 잔류항균물질 비교 조사 -서울지역 도축 소와 돼지를 중심으로-
변정옥 ( Jung Ok Byun ),강영일 ( Young Il Kang ),이달주 ( Dal Ju Lee ),황래홍 ( Lae Hong Hwang ),이양수 ( Yang Soo Lee ),이병동 ( Byung Dong Lee ) 한국가축위생학회 2002 韓國家畜衛生學會誌 Vol.25 No.3
This study was carried out to compare the residual antibiotic materials in muscles of slaughter cattle and swine from slaughterhouses in Seoul from 2000 to 2001 by EEC-4-plate method, Charm Il and HPLC method. 1. Residual antibiotic materials were detected from 95 samples(0.8%) by EEC-4-plate and 57 samples(10.2%) by Charm Il. The final HPLC method determined the positives are 43(45.3%) and 27(47.3%) respectively. 2. The detection ratios were 45% by EEC-4-plate and 47% by Charm Il. 3. Seventy samples were classified as tetracyclines 56(75.7.4%), sulfonamides 10(14.9%), β-lactam 6(8.1%) chloramphenicol 1(1.4%). Three of them were confirmed to be positive simmultaneously for tetracyclines, sulfonamides and chloramphenicol. 4. The highest residual concentration of chlortetracycline, oxytetracycline, sulfamethazine, sulfadimethoxine, sulfaquinoxaline, penicillin, ampicillin and chloramphenicol were 0.34, 11.29, 68.16, 0.13, 4.0, 0.12, 0.4 and 0.04ppm, respectively.
과산화수소-케로신 엔진을 이용한 지상 및 고고도 추력에 대한 실험적 연구
이양석(Yang-Suk Lee),김중일(Joong-Il Kim) 한국산학기술학회 2019 한국산학기술학회논문지 Vol.20 No.10
고농도 과산화수소와 케로신을 추진제로 하는 액체 로켓 엔진을 이용하여 수직형 연소 실험대에 고고도 모사용 디퓨저와 기 검증된 추력 측정 장치를 장착하여 지상 및 고고도 모사 연소 실험 설비를 구축하였으며, 고도에 따른 추력특성을 고찰하였다. 선행으로 고고도 모사용 디퓨저의 특성 및 시동압력을 검증하기 위하여 1:4.8 스케일로 축소한 디퓨저를 설계 및 제작하였다. 축소형 디퓨저는 질소 가스를 이용하여 cold flow test를 수행하여 성능 및 시동 특성을 확인하였으며, 그 결과 연소 실험용 디퓨저의 성능 안정성과 시동 특성을 확보하였다. 수직형 연소 실험대에 고고도 모사용 디퓨저와 추력 측정 장치를 장착하고, 시스템 저항에 대한 추력 보정식을 도출하였다. 추력 보정식은 실제 연소 실험전에 수행한 추력 단계별 실험과 진공 단계별 실험을 통하여 도출하였다. 작동 고도가 10km인 노즐을 설계, 제작하여 지상 연소 실험 및 고고도 모사 연소 실험을 수행하여 작동 고도 변화에 따른 추력 특성을 분석하였다. 추력 측정 장치에서 계측한 추력값을 이용하여 실제 추력을 각각의 보정식을 이용하여 계산하였다. Ground and high altitude simulated combustion experiments were conducted using a liquid rocket engine with hydrogen peroxide and kerosene as the propellant. A ground and high altitude simulated combustion test facility was constructed by installing a high altitude model diffuser and TMS (Thrust Measuring System) on a vertical combustion test bench. The thrust characteristics according to altitude were investigated using the combustion test equipment. The diffuser was designed on a 1:4.8 scale to verify the characteristics of the high diffusing diffuser and starting pressure. The cold flow tests were conducted using nitrogen gas, and the performance characteristics and starting characteristics of the scale down diffuser were verified. A diffuser and TMS were installed on the vertical combustion test bench, and the thrust correction equations for the system resistance were derived. The thrust correction equations were derived from the step test and vacuum step test before the actual hot firing test. Nozzles with an operating altitude of 10km were designed. Hot firing tests were conducted to analyze the thrust characteristics according to the operating altitude changes. The actual thrust was calculated using each correction equation with the thrust value measured by the TMS.
한일용,이양행,황윤호,Han, Il-Yong,Lee, Yang-Haeng,Hwang, Yun-Ho 대한흉부심장혈관외과학회 1997 Journal of Chest Surgery (J Chest Surg) Vol.30 No.11
Lung hernia is defined as a protrusion of lung parenchyma beyond the confines of the musculoskeletal thorax. To date, less than 300 cases have been reported in the literature. The patients were 37 & 57-year-old men who had traumatic rib fractures in the past, whose chief complaint was a painless soft bulging mass increased in size during expiration or coughing and diminished during inspiration or quiet breathing. The primary repair was performed without any p stoperative recurrance. We report two cases of acquired herniation of lung first time in Korea with a brief review of literature. 폐탈출증은 근골격으로 구성된 흉곽 밖으로 폐실질이 빠져나와 돌출되는 것으로, 최근까지 문헌으로 보고된 예는 300 례 미만이다. 환자는 늑골 골절을 포함한 외상을 입었던 과거력을 가진 37세와 57세 남자 이며 주소는 전흉부에 무통성의 부드러운 종괴로 호기시나 기침시 그 크기가 증가하였고, 흡기시 혹은 조용한 호흡시에는 감소하였다. 수술은 흉벽 결손에 대한 일차 봉합술을 시행하였으며, 술후 재발은 아직 까지 관찰되지 않았다 저자들은 지금까지 국내 발생보고 예가 없는 후천성 폐탈출증 2례를 수술 치험하였기에 문헌고찰과 함께 보고하는 바이다.