족관절 안정성의 예상인자 -격자각과 비골의 길이-

이상욱,고상봉,신민철,이병관,Lee, Sang-Wook,Koh, Sang-Bong,Shin, Min-Cheul,Lee, Byoung-Kwan 대한족부족관절학회 2004 대한족부족관절학회지 Vol.8 No.1

Purpose: The aim of this study was to investigate the usefulness of mortise angle and fibular length measured in radiologic findings in predicting the ankle stability. Materials and Methods: One hundred cases fifty cases were randomly selected volunteers with normal ankle function and the other fifty cases were randomly selected patients whose ankle were treated in our hospital and who were followed for over 1 years with good results. A specific experimental fixture were made to get the even AP and lateral view and objective stress view. Results: The mortise angle and fibular length was not statistically significant to the degree of talar tilt angle under valgus or varus stress and that of displacement under anterior or posterior stress. Conclusion: The mortise angle and fibular length was not the objective predicting factors on the ankle stability. Maintenance of constrained talus in dynamic status is most important factors in determining the ankle stability.

두경부 편평상피세포암종에서 $^{18}FDG-PET$을 이용한 방사선치료 반응평가

이상욱,류진숙,이병용,김종훈,안승도,신성수,김상윤,남순열,송시열,윤상민,박진홍,김성배,김재승,Lee Sang-Wook,Ryu Jin-Sook,Yi Byong-Yong,Kim Jong-Hoon,Ahn Seung-Do,Shin Seong-Soo,Kim Sang-Yoon,Nam Soon-Yuhl,Song Si-Yeol,Yoon Sang-Min,Park Jin-H 대한두경부종양학회 2003 대한두경부 종양학회지 Vol.19 No.1

Purpose: To evaluate the efficacy of positron emission tomography with 2-[F-18] fluoro-2-deoxy-D-glucose in discrimination of response in the nasopharyngeal carcinoma patients who treated with radiotherapy. Methods and Materials: Twenty-four patients who underwent FDG-PET scan before and after radiotherapy for no disseminated head and neck carcinoma at the Asan Medical Center between August 2001 and September 2002 were evaluate by prospective analysis. First FDG-PET scan performed before radiotherapy within 1 month, and second FDG-PET scan performed 1 month after radiotherapy. FDG-PET images were analyzed by standard uptake value (SUV). Follow-up period was more than 6 months. Results: The pretreatment SUV was 3.4-14.0 (median: 6.0) and posttreatment SUV was ground level-7.7 (median: 2.0). The overall sensitivity and specicity of FDG-PET to evaluate residual tumors in the nasopharyngeal carcinoma patients were 94% and 94%. Conclusion: FDG-PET is effective in evaluation of radiation response in the nasopharyngeal carcinoma. We think that the timing of one month after finished radiotherapy FDG-PET scan was not too fast to evaluation of radiation response.

편측 종골 골절의 수술적 치료의 예후 관련 인자

이상욱,고상봉,이현섭,Lee, Sang-Wook,Ko, Sang-Bong,Lee, Hyun-Sub 대한족부족관절학회 2006 대한족부족관절학회지 Vol.10 No.2

Purpose: To study prognostic factors of unilateral calcaneus fracture underwent surgery. Materials and Methods: We selected appropriate 60 cases of 236 calcaneus fracture cases between March 1985 and March 2004, and analyzed the correlation between sex, age, smoking, injury mechanism, Essex-Lopresti classification of calcaneus fracture, preoperative Bohler angle, postoperative Bohler angle, postoperative 1 year Bohler angle and Visual Analogue Scale (VAS), P.S. Kerr's Calcaneal Fracture Score (CFSS). The average age was 41.4 and average follow up period was 74 (12 to 240) months. Results: For follow up period, average VAS is 3.43 and CFSS is 81.23. The sex, age, smoking, injury mechanism, and preoperative, postoperative, postoperative 1 year Bohler angle had no correlation with the prognosis. But the Essex-Lopresti classification of calcaneus fracture, tongue type had better prognosis than joint depression type (VAS : p=0.041, CFSS : p=0.021). Conclusion: In unilateral calcaneus fracture, the sex, age, smoking, injury mechanism, preoperative Bohler angle, postoperative Bohler angle, postoperative 1 year Bohler angle had no correlation with the prognosis of fracture, but in Essex-Lopresti classification, the tongue type fracture had better prognosis than the joint depression type.

해조가 2,4,6-trinitrobenzene-sulfonic acid로 유발된 염증성 장질환 동물모델에 미치는 영향

이상욱,류봉하,박재우,Lee, Sang-Wook,Ryu, Bong-Ha,Park, Jae-Woo 대한한방내과학회 2010 大韓韓方內科學會誌 Vol.31 No.2

Objectives : The aim of the current study was to investigate the effects of Sargassum (Sargassum pallidum (TURN.) C. AG.; SP) on the experimental colitis induced by 2,4,6-trinitrobenzene sulfonic acid (TNBS) in mice. Methods : ICR mice were divided into 7 groups (NOR, CON, $SS50\times5$, $SP20\times3$, $SP50\times3$, $SP20\times5$, $SP50\times5$). TNBS processing was intrarectally applied to all experimental groups on the 3rd experiment day, except the normal group (NOR). For investigating the prophylactic effect, SP at doses of 20 mg/kg ($SP20\times5$) and 50 mg/kg ($SP50\times5$) were orally administered for 5 days. The SP at doses of 20 mg/kg ($SP20\times3$) and 50 mg/kg ($SP50\times3$) were orally administered for 3 days after the colitis induction in order to check the effect of treatment. As a positive control group, sulfasalazine 50 mg/kg ($SS50\times5$) was administrated. Macroscopic findings of epithelial tissue on mice were measured by colon length and macroscopic score. Histologic findings were also checked by crypt cell, epithelial cell, inflammatory cell and edema of submucosa. We measured the ability of SP to inhibit lipid peroxidation and myeloperoxidase activity. We also measured levels of the inflammatory markers, interleukin (IL)-$1\beta$ and cyclooxygenase-2 (COX-2), its transcription factor activation, phospho-NF-${\kappa}B$ (pp65), in the colon by enzyme-linked immunosorbent assay and immunoblot analysis. We measured activation of fecal bacterial enzyme, $\beta$-glucuronidase and degradation activation of fecal glycosaminoglycan (GAG), and hyaluronic acid. Results : Oral administration of SP on mice inhibited TNBS-induced colon shortening and myeloperoxidase activity in the colon of mice as well as IL-$1\beta$ and COX-2 expression. SP also inhibited TNBS-induced lipid peroxidation and pp65 activation in the colon of mice. SP inhibited $\beta$-glucuronidase activation and fecal hyaluronic acid degradation activation as well. Conclusions : SP could be a possible herbal candidate and preventive prebiotic agent for treating inflammatory bowel disease (IBD). Further experiments to differentiate effects of SP on IBD, such as other solutions and extracting times, might be promising.

압전복합재료를 이용한 초음파 트랜스듀서의 음향 특성

이상욱,류정탁,남효덕,김연보,Lee, Sang-Wook,Ryu, Jeong-Tag,Nam, Hyo-Duk,Kim, Yeon-Bo 한국음향학회 2007 韓國音響學會誌 Vol.26 No.2

본 연구에서는 압전세라믹과 고분자재료를 사용하여 다이스와 필 방법으로 2-2형 압전복합재료를 제작하고 이것을 이용하며 초음파 센서를 설계하고 제작하여 전기적 및 음향 특성을 조사하였다. 제작된 시편의 공진특성은 유한요소 해석 결과와 임피던스 분석기(HP4194A)를 이용하여 실제로 측정한 결과와 유사하게 나타났다. 2-2형 압전복합재료의 고유음향 임피던스는 PZT의 부피분율이 감소함에 따라 선형적으로 감소하였다. 이것을 이용하여 제작된 초음파 센서의 공진특성 및 전기기계결합계수는 PZT의 부피분율이 0.6일 때 가장 우수하였다. 또한, 이것의 음향특성을 측정한 결과 PZT 부피분율이 0.6일때 진폭, 주파수 대역폭, 울림감쇠 특성 등이 가장 우수하게 나타났으며, 단일 압전세라믹으로 제작된 센서에 비하여 상당히 우수한 감도 특성을 나타내었다. We have investigated on the development of 2-2 type piezocomposites that have better piezoelectric activity and lower acoustic impedance than those of conventional piezoceramics. In this study, we have investigated the piezoelectric and acoustic properties of 2-2 type piezocomposites sensor which was fabricated using dice-and-fill technique for the different volume fraction of PZT. The specific acoustic impedance of 2-2 type piezocomposites decreased linearly when PZT volume fraction was decreased. The resonance characteristics measured by an impedance analyzer(HP4194A) were similar to the analysis of finite element method (FEM). The resonance characteristics and the electromechanical coupling factor were the best when the volume fraction PZT was 0.6. It also showed the highest result from the standpoint of sensitivity, bandwidth and ring-down property and so on at the same condition. The specific characteristics show that the 2-2 type piezocomposites turned out to be superior to the ultrasonic sensor composed by single phase PZT.

피라미드 볼륨 교차기법을 이용한 영상기반의 3차원 형상 복원

이상욱,Lee Sang-Wook 한국정보통신학회 2006 한국정보통신학회논문지 Vol.10 No.1

The image-based 3D modeling is the technique of generating a 3D graphic model from images acquired using cameras. It is being researched as an alternative technique for the expensive 3D scanner. In this paper, I propose the image-based 3D modeling system using calibrated camera. The proposed algorithm for rendering 3D model is consisted of three steps, camera calibration, 3D shape reconstruction and 3D surface generation step. In the camera calibration step, I estimate the camera matrix for the image aquisition camera. In the 3D shape reconstruction step, I calculate 3D volume data from silhouette using pyramidal volume intersection. In the 3D surface generation step, the reconstructed volume data is converted to 3D mesh surface. As shown the result, I generated relatively accurate 3D model. 영상 기반 3차원 모델링은 카메라로부터 획득된 영상을 입력으로 하여 3차원 그래픽 모델을 생성하는 기술로 고가형 3D 스캐너의 대체 기술로 연구되어지고 있다. 본 논문에서는 피라미드 볼륨 교차기법을 이용한 영상 기반 3차원 모델링 시스템을 제안한다. 3차원 모델을 생성하기 위한 제안 알고리즘은 카메라 보정 단계, 3차원 형상 복원단계, 3차원 표면 생성 단계로 이루어진다. 카메라 보정 단계에서는 영상 획득용 카메라에 대한 카메라 행렬을 계산하며 3차원 형상 복원 단계에서는 실루엣 기반 피라미드 볼륨 교차 기법에 의해 실 3차원 형상을 생성한다. 3차원 표면 생성 단계에서는 3차원 형상 복원 단계의 결과인 복원 복셀 공간을 그물망 형태의 3차원 표면을 생성시킨다. 실험 결과 제안 알고리즘이 비교적 정확하게 3차원 모델을 생성함을 확인하였다.

도이치말에서의 부정유형에 대하여

이상욱,Lee Sang-Wook 한국독어학회 2000 독어학 Vol.2 No.-

Die Negation im Deutschen wird in der Tradition, besonders aus dem syntaktischen Aspekt, in zwei verschiedenen Arten unterschieden: Sondemegation(Wortnegation oder Konstituentennegation) vs. Satznegation. Demzufolge bei der Satznegation bezieht sich das Negationswort auf die gesamte Aussage, d.h. die vom gesamten Satz $ausgedr\"{u}ckten$ Propositionskomplexe und bei der Sondernegation auf Teile des gesamten Satzes. Diese Unterscheidung wird hauptsachlich durch die Stellungsmoglichkeiten von 'nicht' $begr\"{u}ndet$. Sie wird aus kommunikativ orientierten Aspekten problematisiert. Solche $Ans\"{a}tze$ gehen davon aus, $da{\ss}$ die Negation eine Blockierungsoperation bei der Bearbeitung bereits vorhandener Kenntnisse ist. Aus kommunikativ orientierten Aspekten wird nur bei der Satznegation von 'Negierung' gesprochen, und bei der Sondernegation liegt nur eine negierte Teilstruktur vor, die den Chakrakter der Affirmierung des Gesamtsatzes zwar modifiziert, aber nicht aufhebt. Als $vorla\"{u}figes$ Fazit stellt man fest, $da{\ss}$ die Beschreibung der Negation aus kommunikativ-pragmatischen Sichten die Unterscheidung Satznegation/Sondernegation nicht $\"{u}berfl\"{u}ssig$ macht. Um die Negation besser zu ermitteln, werden nicht nur unterschiedliche syntaktische $Stellungsm\"{o}glichkeiten$ von 'nicht' $ber\"{u}cksichtigen$, sondern auch die im Satz verschieden gegebene Intonation und auch kommunikative $Handlungszusammenh\"{a}nge$.

간암에서 호흡주기를 고려한 2-차원 방사선 치료 방법과 3-차원 입체조형 치료방법에서 방사선 간염 예측의 비교연구

이상욱,김귀언,정갑수,이창걸,성진실,서창옥,Lee Sang-wook,Kim Gwi Eon,Chung Kap Soo,Lee Chang Geol,Seong Jinsil,Suh Chang Ok 대한방사선종양학회 1998 Radiation Oncology Journal Vol.16 No.4

목적 : 방사선치료계획시 호흡에 의한 장기의 움직임이 고려하는 경우 호흡이 방사선치료에 따른 합병증 발생에 미치는 영향을 분석하고자 하였다. 대상 및 방법 : 3차원 입체조형치료를 받은 간암 환자 4례를 대상으로 하여 방사선치료 계획용컴퓨터상에서 재분석을 하였다. 호흡주기에 따라 방사선치료를 시행 받는다고 가정하여 계획용표적체적의 상하 범위를 줄여 기존의 2-차원 치료계획을 시행한 경우와 자유롭게 호흡하면서 계획된 3-차원 입체조형치료에서 정상간과 주변정상장기의 선량체적히스토그람과 normal tissue complication probability(NTCP)를 비교하였다. 결과 : 간의 호흡에 의한 상하 운동범위는 2-3cm 이었고 호흡주기에 따른 기존의 2차원 방사선치료 방법과 자유롭게 호흡하면서 시행된 3-차원적 입체조형치료 간의 계획용표적체적과 잔여정상간, 주변정상장기의 선량체적히스토그람의 뚜렷한 차이는 관찰할 수 없었다. 또한 정상잔여간의 NTCP의 차이도 관찰할 수 없었다. 결론 : 간에 대한 방사선치료시 호흡에 의해 장기의 움직임을 고려한 방사선치료계획은 방사선치료에 따른 합병증 발생에 매우 중요한 역할을 할 것으로 생각되었고 향후 이 문제점을 극복할 수 있는 많은 연구가 필요 할것으로 생각된다. Purpose : To evaluate influences associated with radiation treatment planning obtained with the patient breathing freely. Materials and Methods : We compared reduction or elimination of planning target volume (PTV) margins with 2-D conventional plan with inclusion of PTV margins associated with breathing with 3-D conformal therapy. The respiratory non gated 3-D conformal treatment plans were compared with respiratory gated conventional 2-D plans in 4 patients with hepatocellular carcinomas. Isodose distribution, dose statistics, and dose volume histogram (DVH) of PTVs were used to evaluate differences between respiratory gated conventional 2-D plans and respiratory non gated 3-D conformal treatment plans. In addition. the risk of radiation exposure of surrounding normal liver and organs are evaluated by means of DVH and normal tissue complication probabilities (NTCPs). Results : The vertical movement of liver ranged 2-3 cm in all patients. We found no difference between respiratory gated 2-D plans and 3-D conformal treatment plans with the patients breathing freely. Treatment planning using DVH analysis of PTV and the normal liver was used for all patients. DVH and calculated NTCP showed no difference in respiratory gated 2-D plans and respiratory non gated 3-D conformal treatment plans. Conclusion : Respiratory gated radiation therapy was very important in hepatic tumors because radiation induced hepatitis was dependent on remaining normal liver volume. Further investigational studies for respiratory gated radiation.

특징 기반 다중 물체 추적 시스템에 관한 연구

이상욱,설성욱,남기곤,권태하,Lee, Sang-Wook,Seol, Sung-Wook,Nam, Ki-Gon,Kwon, Tae-Ha 대한전자공학회 1999 電子工學會論文誌, S Vol.s36 No.11

본 논문은 연속 영상에서 윤곽선과 특징을 이용하여 주위 환경 변화에 적응가능한 다중 물체 추적 방법을 제안한다. 적응 배경 모델을 사용하여 주위 환경 변화에 적응케 했으며, 물체 분할 모델은 배경 영상과 현재 영상의 차영상에서 국부 영상의 임계값 이상의 화소를 찾아 연결한 영역을 추출한다. 특징 추출과 물체인식모델은 탐색 창 내에서 발견된 다중 물체의 데이터 연상 문제를 해결하기 우해 사용되며, 실시간 추적을 위해 칼만 필터를 사용하였다. 제안된 방법을 도로 영상에 적용한 결과 다중 차량 추적이 정확히 이루어짐을 실험을 통해 보였다. In this paper, we propose an adaptive method of tracking multiple moving objects using contour and features in surrounding conditions. We use an adaptive background model for robust processing in surrounding conditions. Object segmentation model detects pixels thresholded from local difference image between background and current image and extracts connected regions. Data association problem is solved by using feature extraction and object recognition model in searching window. We use Kalman filters for real-time tracking. The results of simulation show that the proposed method is good for tracking multiple moving objects in highway image sequences.

2-2형 압전복합재료의 전기적 특성

이상욱,남효덕,류정탁,김연보,Lee, Sang-Wook,Nam, Hyo-Duk,Ryu, Jeong-Tag,Kim, Yeon-Bo 한국전기전자재료학회 2005 전기전자재료학회논문지 Vol.18 No.8

We have investigated on the development of 2-2 mode piezocomposites that have better piezoelectric activity and lower acoustic impedance than those of conventional piezoceramics. In this study, we have investigated the electrical properties and acoustic impedance of 2-2 mode piezocomposite which were fabricated using the dice-and-fill technique for the different volume fractions of PZT The volume shrinkage of polymer is an important factor in 2-2 mode piezocomposites fabrication. The thickness mode electromechanical coupling factor($\kappa_t$) of PZT was compared with that of piezocomposites. It was shown that the 2-2 mode piezocomposites were much better than the PZT only. The acoustic impedance of 2-2 mode piezocomposites decreased linearly when PZT volume fraction was decreased.