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임승길,김경래,이수곤,이관우,황성오,허갑범,이현철,이혁우 대한내분비학회 1989 Endocrinology and metabolism Vol.4 No.1
Autoimmune hypoglycemia is characterized by hyperinsulinemia, fasting hypoglycemia, and presence of insulin autoantibody without previous exposure to exogenous insulin. Though this conditions were reported exclusively in Japan, we recently experienced the first case of autoimmune hypoglycemia in Korea and present it with a literature review. (J Kor Soc Endocriuol, 4: 72~76, 1989)
인슐린 치료후 발생한 인슐린 항체에 의한 저혈당증 2예
김경아,이관우,김미림,김여주,장재남,배성권,손병관 대한내분비학회 1996 Endocrinology and metabolism Vol.11 No.2
Hirata et al. first described the association of insulin antibodies with hypoglycemia attacks and decreased glucose tolerance in a patient who had not previously received insulin injections. Since that time there have been additional reports in the Japanese literature. Insulin antibodies are present in most of the patients who received insulin for a period of time, usually exceeding six weeks. There were several reports of hypoglycemia in patients with non-insulin-dependent diabetes mellitus who had developed insulin antibody after insulin administration and also in patients with insulin dependent diabetes mellitus. It is well known that either insulin antibody to the lower affinity site or insulin receptor antibody can be a cause of hypoglycemia. Recently, we experienced two cases of hypoglycemia in patient with insulin dependent diabetes mellitus and non- insulin- dependent diabetes mellitus who had developed insulin antibody after insulin administration. Hereby we present these cases with review of the literature(1 Kor Soc Endocrinol 11:240 ~246, 1996).