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Pyogenic Spondylitis in a Healthy Adult Caused by Burkholderia cepacia
양병혁,이미숙,이정희,이희주 대한감염학회 2008 Infection and Chemotherapy Vol.40 No.4
Burkholderia cepacia is an important pathogen of humans in both immunocompromised or hospitalized patients.This aerobic gram-negative rod causes various clinically significant infections such as pneumonia, bacteremia, urinary tract infection, peritonitis, endophthalmitis, and keratitis. This uncommon pathogen is mainly associated with cystic fibrosis, dialysis, and immunocompromised states. We observed a 73-year-old woman without any underlying diseases, who had both lower leg pain and fever. She was later found to have spondylitis with epidural abscess at L5-S1. Culture of the epidural abscess revealed the growth of B. cepacia. To the best of our knowledge, this is the first case of pyogenic spondylitis caused by a rare infection of B. cepacia to be reported in Korea
Pyogenic Spondylitis in a Healthy Adult Caused by Burkholderia cepacia
Yang, Byung Hyuk,Lee, Mi Suk,Lee, Jung-Hee,Lee, Hee-Joo 대한감염학회 2008 감염과 화학요법 Vol.40 No.4
Burkholderia cepacia is an important pathogen of humans in both immunocompromised or hospitalized patients. This aerobic gram-negative rod causes various clinically significant infections such as pneumonia, bacteremia, urinary tract infection, peritonitis, endophthalmitis, and keratitis. This uncommon pathogen is mainly associated with cystic fibrosis, dialysis, and immunocompromised states. We observed a 73-year-o1d woman without any underlying diseases, who had both lower leg pain and fever. She was later found to have spondylitis with epidural abscess at L5-S1. Culture of the epidural abscess revealed the growth of B. cepacia. To the best of our knowledge, this is the first case of pyogenic spondylitis caused by a rare infection of B. cepacia to be reported in Korea
인슐린종으로 부분 췌장절제술 10년 후 간전이로 재발한 악성 인슐린종
강양일,양병혁,전숙,오승준,우정택,김성운,김진우,김영설,이주희,고관표 대한내분비학회 2006 Endocrinology and metabolism Vol.21 No.1
저자들은 과거 췌장 미부에 국한된 인슐린종을 진단하여 부분적인 췌장 절제술을 시행한 환자에서, 10년 후 저혈당 증상으로 내원하여 혈청학적인 검사상 인슐린종을 진단하였고 복부컴퓨터촬영으로 남은 췌장부위에는 종양 소견이 없으면서 간으로의 전이성 병변만을 보인 악성 인슐린종을 진단하였다. 부분적인 간 절제술 후 인슐린을 분비하는 전이성 인슐린종으로 확진하였으며 수술 후 증상이 호전된 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Malignant insulinomas are very rare endocrine tumours with a variable clinical course. Here, a case of a malignant insulinoma, resected from the tail of the pancreas 10 years previously, which was found to have hepatic metastasis, is reported. A pancreatic mass, without evidence of metastasis, has been found using an abdominal CT scan and intra-operative ultrasonography 10 years previously. Recently, the patient has suffered from dizziness, sweating and an altered mentality. Hyperinsulinemia was diagnosed from the biochemical laboratory finding. An abdominal CT scan and intra-operative abdominal sonography showed multiple hepatic metastasis, without local recurrence in pancreas. Therefore, a partial hepatic segmentectomy was performed. Immunohistochemical staining of the postoperative specimen was strongly positive for insulin. The postoperative biochemical response was normalized, and the patient experienced no further hypoglycemic symptom (J Kor Soc Endocrinol 21:68~73, 2006).
백선경,양병혁,김시영,윤휘중,정경환,임천규,조경삼 대한혈액학회 2009 Blood Research Vol.44 No.1
In this report, we present a case of a patient with Philadelphia chromosome-positive (Ph+) B-cell acute lymphoblastic leukemia after renal transplantation. The patient, a 65-year-old man, had received a kidney transplantation 20 years prior to diagnosis with Ph+ precursor B-cell ALL. Because he was refractory to intensive chemotherapy and had refused to receive additional intensive chemotherapy, he was treated with imatinib and dexamethasone. While this patient experienced a complete hematologic and cytogenetic response, he did not show a complete molecular remission. Eighty days after imatinib combination therapy, the patient relapsed and died from intracerebral hemorrhage.