2002년 추계학술발표회 논문집 : A. 발표장 (306호) ; 상수처리 : 소금물 전기분해 혼합산화제의 상승 소독효과

손현주 ( Hyun Ju Son ),조민 ( Min Cho ),윤제용 ( Je Yong Yoon ) 한국물환경학회 ( 구 한국수질보전학회 ) 2002 공동 추계학술발표회 Vol.2002 No.-

상수처리 : 소금물 전기분해 혼합산화제의 상승 소독효과

손현주 ( Hyun Ju Son ),조민 ( Min Cho ),윤제용 ( Je Yong Yoon ) 대한상하수도학회 2002 공동추계 학술발표회 논문집 Vol.2002 No.-

건조방법과 첨가물에 따른 마 현탁액의 점도

김인현(In Hyun Kim),손현주(Hyun Ju Son),정구민(Koo Min Chung) 한국식품과학회 2006 한국식품과학회지 Vol.38 No.3

가열처리에 따른 구기자 추출물의 성분변화

이상덕(Sang Duck Yi),이미현(Mi Hyun Lee),손현주(Hyun Ju Son),복진영(Jin Young Bock),성창근(Chang Keun Sung),오만근(Man Jin Oh),김찬조(Chan Jo Kim) 한국응용생명화학회 1996 Applied Biological Chemistry (Appl Biol Chem) Vol.39 No.4

Fundamental data for new type of product development from Lycii fructus was experimentally determined. The chemical composition, and Hunter value changes, optimum extraction, volatile components of extract under different extraction conditions and heat treatment were mainly studied. Results are summarized as follows. The proximate compositions of dried Lycii fructus were water 21.8%, total sugar 27.6%, reducing sugar 15.29%, crude protein 14.29%, crude fat 5.65%, crude fiber 7.48%, and ash 7.98% in percent scale, respectively. Extracted yield on the basic of solid extract was getting increased when more solvent was used for extraction. The most recommendable extraction was 1 to 10 part of sample to solvent ratio. When water was employed as extraction solvent, the highest amount of solid extract was obtained. Extract of Lycii fructus in terms of yields and color was most acceptable when raw sample was treated 8 minute roasting at 180℃ and 60 minute heating at 120℃, respectively. Major volatile components of fresh Lycii fructus were to hexadecanoic acid, methyl linoleate, benzyl alcohol, dimetane benzene by GC/MS. By she roasting of raw sample, the compounds of 2-methyl-2buthenal, 1,4-dimethyl benzene, and benzyl alcohol were reduced. Whereas, methyl thiopropanol, benzene acetaldehyde and ethyl linoleate were slightly increased.

단일양막 쌍태임신의 주산기 예후

조윤성 ( Yun Sung Jo ),고현선 ( Hyun Sun Ko ),장동규 ( Dong Gyu Jang ),최윤진 ( Youn Jin Choi ),손현주 ( Hyen Ju Son ),김사진 ( Sa Jin Kim ),신종철 ( Jong Chul Shin ),이귀세라 ( Guisera Lee ) 대한산부인과학회 2010 Obstetrics & Gynecology Science Vol.53 No.10

목적: 본 연구에서는 단일양막 쌍태임신의 주산기 예후에 관하여 알아보고자 하였다. 연구 방법: 1997년 1월부터 2010년 4월까지 가톨릭대학교 부속병원인 성빈센트병원과 여의도성모병원에서 단일양막 쌍태임신으로 진단받은 증례 15명과 출산아의 임상 기록을 조사하여 후향적 연구를 시행하였다. 결과: 단일양막 쌍태임신은 총 1,112명의 쌍태임신 중 15예로 쌍태임신의 1.3%에 해당되었으며 15예 중 2예는 결합쌍태아였다. 15예의 임신 중 20주 이전에 유산된 경우는 3예(20%), 20주 이상 임신이 유지된 경우는 12예였다. 이 12예 중 일측 태아가 사망한 경우는 3예(25%), 양측 태아가 모두 자궁 내 사망한 경우는 1예(8.3%)였다. 20주 이상 임신이 유지된 태아 24명 중 출생 시 생존아는 18명(75%), 신생아기 28일까지 생존한 경우는 15명(62.5%)으로 주산기 사망은 24예 중 9예(37.5%)였다. 치명적 기형과 선천성 심장기형의 발생률은 각각 20%, 23.3%였다. 분만 주수는 평균 31.4±4.53주이며, 생존아 18명 중 16명(84.2%)이 신생아중환자실에 입원하였다. 이 중 3명은 출생 당일에 사망하였으며 나머지 13명의 평균 재원일수는 32.0±29.3일(3~114일)이었다. 주산기 사망의 주된 원인은 조산, 선천성 기형, 20주 전의 유산과 탯줄 꼬임으로 추정되는 자궁 내 사망이다. 결론: 단일양막 쌍태아는 높은 주산기 사망률을 보이며 임신 32주 이상 자궁 내에서 생존할 수 있는 확률은 약 1/3 정도로 낮다. 향후 높은 주산기 사망률의 원인과 사망률을 낮추기 위한 연구가 필요하다. Objective: The purpose of this study was to determine the perinatal outcome in monoamniotic twin pregnancies and to review the recently published literature about the topic. Methods: This retrospective study examined the records of prenatally diagnosed monoamniotic twin pregnancy casese in our institution between January 1997 and April 2010. Results: Among 1,112 twin pregnancies, there were 15 (1.3%) monoamnionic twins, including 2 conjoined twin pregnancies. Twelve (80%), 9 (60%), 5 (33.3%), and 4 pregnancies (26.7%) delivered after 20, 30, 32, and 34 weeks, respectively. Among 12 pregnancies that continued after 20 weeks of gestation, three cases showed one-fetal death and one, both-fetal death. The perinatal mortality rate (from 20 weeks of gestation to 28 days after birth) was 37.5%. The incidence of lethal anomalies and congenital heart anomalies was 20% and 23.3%, respectively. The mean gestational age at delivery was 31.4±4.53 weeks; 16 of 18 neonates (84.2%) were admitted to the neonatal intensive care unit (NICU). Three neonates expired on the first day after birth. The mean duration of the NICU stays for 13 live neonates was 32.0±29.3 days (range, 3 to 114 days). The main causes of perinatal deaths were preterm birth, congenital anomalies, pregnancy loss before 20 weeks, and intrauterine fetal demise that might have resulted form cord entanglement. Conclusion: Perinatal mortality in monoamniotic twins was still very high and the survival rate after 32 weeks of gestation is approximately one-third. Further studies are needed to improve the perinatal mortality.

유소아 신질환에서 치료후 신기능회복에 대한 99mTc-DMSA 신티그램의 임상적 고찰

김병수(Byung Soo Kim),문태용(Tae Yong Moon),윤종병(Chong Byung Yoon),손현주(Hyun Ju Son),김인주(In Ju Kim),이석홍(Suck Hong Lee) 대한핵의학회 1994 핵의학 분자영상 Vol.28 No.1

N/A Authors retrospectively analysed 20 cases of follow-up 99mTc-DMSA renal scans to evaluate renal function recovery after treatment in urologic disorders of infants and children. There were 20 cases with both 99mTc-DMSA renal scans prior to and after therapy in 15 patients below 9 years old. Among them, 10 patients underwent ureteroneocystostomy under the diagnosis of vesicoureteral reflux, two patients pyeloplasty because of obstructive uropathy and one was treated with antibiatics even diagnosis of UPJ stricture. We have got the quantified uptake rate of Tc-DMSA renal scan by using the regression equation as y=0.591x 2.105 (y=the quantified uptake rate, x=the sirnple uptake rate). The number of kidneys performed proper therapy were 29, and the cases with more increased radiotracer uptake rate in the follow-up 99mTc-DMSA renal scans were 20 in number as 69% in frequency. 19 cases with improved renal function on 99mTc-DMSA renal scans didnt show any significant difference related t.o aging or recovery duration after therapy. The 99mTc-DMSA renal scans were not useful to evaluate renal function recovery in infants and children, but could be good tests to assess residual renal function prior to or after treatment.

통계량에 의한 정도관리 -면역혈청 검사를 중심으로-

장상우 ( Sang Wu Chang ),김남용 ( Nam Yong Kim ),김진각 ( Jin Gak Kim ),홍웅기 ( Wung Gi Hong ),손현주 ( Hyun Ju Son ) 대한임상검사과학회 2002 대한임상검사과학회지(KJCLS) Vol.34 No.2

Statistical inference is the use of a probability theory to make inferences about a population from sample data. Suppose we want to estimate the characteristics of a population such as the target value (monthly average mean) in a laboratory. We obtained data from a sample and used the results to make inferences about the population. A sample population is drawn from a lot number made by manufactures, and collection of all subjects or objects of interest. A sample is a subset of the population used to make inferences about the characteristics of the population. A population parameter is a numerical characteristic of a population, a fixed and usually unknown quantity. Data are xalues measured or recorded on the sample. Sample statistics are numerical characteristics of the sample data such as the mean, CV, SD, proportion or variance. It can be used to provide estimates of the corresponding population parameters. Different samples give different values for sample statistics. By taking many different samples and calculating a sample statistics for each sample (e.g. the sample mean) , you could then draw a histogram of all sample means. A statistic from a sample or randomized experiment can be regarded as a random variable and the histogram is an approximation to its probability distribution. The term sampling distribution is used to describe this distribution, i.e. how the statistic (regarded as a random variable) varies if random samples are repeatedly taken from the population. Bias is distance between the parameter and expected value of sample statistics. If the sampling distribution is known then the ability of the sample statistics to estimate the corresponding population parameter can be determined. In particular, the sampling distribution determines the expected value and variance of the sampling statistics. If the expected value of the statistics is equal to the population parameter, the estimator is unbiased. If the variance of the statistics is ’small’ and it is also unbiased then an observed statistic is likely to be close to the population parameter. Random sampling is a sampling technique where we select a group of subjects (a sample) for study from a larger group (a population). Each individual is chosen entirely by chance and each member of the population has a known, but possibly non-equal, chance of being included in the sample. Variation in a process can be defmed as the amount values from about the average value for a given population. It has been demonstrated that variation in a stable process will vaη randomly about the process`` average value within the process’ capabilities if no outside force is acting upon it. The goal of the total error program should be to minimize and eliminate if possible these variations and to operate a process such that it has the capabi1ity to produce a product within a customers`` specification or better. When variations from outside forces are eliminated, all variations left in the process are inherent to the process and the process is performing at its optimum. In conclusion, one of the best ways is using a target value and standard deviation from statistics in a monthly population that draws samples in order to minimize total error in a clinical laboratory because insert statistics where a vendor is supplied is a veη large variation and it is easy to interpret it. We are sure that the latest data from a monthly population are providing the best information for quality control and reducing bias.

Effects of cultural environments on the phenolic compounds from Solanum melongena L. based on metabolomics

Youn Ok Jung(정연옥),Jun Young Kim(김준영),Seung Kyu Ahn(안승규),Duck Seon Park(박덕선),Suk Soon Bae(배석순),Hyun Ju Son(손현주),Kwan Hyun Nam(남관현),이영둘(Young Dul Kim),Mi Suk Gi(지미숙),Sun His Jung(정순희) 한국약용작물학회 2014 한국약용작물학회 학술대회논문집 Vol.2014 No.2

甲狀腺 機能亢進症에서 백강잠의 抗酸化 效果에 대한 硏究

손현주,박종혁,윤철호,정지천,강정준,서종은,신억섭 대한한방성인병학회 1999 韓方成人病學會誌 Vol.5 No.1

This study was carried out to examine if Bombycis Corpus (BOM) inhibits oxidant-induced lipid peroxidation and therby produces protective effect against thyroxine-induced hyperthyroid rats. In vivo, Triiodothyronine(T3) and thyroxine(T4) were increased in thyroxine treated group. However, they were decreased in BOM extract's pre-applied group. Lipid peroxidation was increased in thyroxine treated group. However, it was decreased in BOM extract's pre-applied group. Xathine oxidase activities and type conversion ratio were increased in thyroxine treated group. However, they were decreased in BOM extract's pre-applied group. Glutathione level and activities of glutathione peroxidase, glutathione S-transferase and glutathione reductase were decreased in thyroxine treated group. However, they were increased in BOM extract's pre-applied group. These results suggest that BOM, in thyroxine-induced hyperthyroid rats, has an increase in the activities of oxygen free radical scavenging enzymes and inhibition of xanthine oxidase activities and thereby prevents lipid peroxidation.

만성 신부전환자에서 당불인내성 예견 지표로서의 Serum Reverse T₃에 관한 연구

손현주,김진수,민태희,경란호 대한내분비학회 1987 Endocrinology and metabolism Vol.2 No.2

To investigate the thyroid hormonal change and the usefulness of serum reverse T_3(rT_3) assay in predicting glucose intolerance in patients with chronic renal failure(CRF), we measured the serum thyroid hormone using radioimmunoassay and HbA_1C. Also we performed oral glucose tolerance test(OGTT) in 17 patients with CRF on hemodialysis therapy and 20 normal control subjects(NS). The following results were obtained: 1) The serum T_3 and T_4 concentrations were significantly lower in patients with CRF(89.11±14.11 ng/dl and 4.93±0.92 ug/dl, respectively) than in NS(156.80±21.38 ng/nl and 9.11±1.65 ug/dl, respectively). 2) The serum rT_3 concentration in patients with CRF was within and below the normal range, but the mean (183.92±52.40 pg/ml) was significantly lower than in NS(250.54±25.75 pg/ml). 3) The serum TSH concentration was within the normal range in patients with CRF. And the mean serum TSH(2.68±1.18 uu/ml) did not differ significantly from that of NS(2.08±1.00 uu/ml). 4) The serum TBG concentration was within the normal range in patients with CRF. But the mean serum TBG(18.32±4.39 ug/ml) was significantly lower than that of NS(28.50±8.97 ug/ml). 5) The serum rT_3 concentration of eight patients with CRF who showed impaired OGTT(226.10±45.97 pg/dl) was significantly higher than that of nine patients with CRF who showed normal OGTT(146.42±16.78 pg/dl). And in the whole patients with CRF, there was significant relationship between blood glucose levels and serum rT_3 concentrations. 6) In patients with CRF, the serum rT_3 assay showed a speccifictity of 100% and a sensitivity of 88% in predicting glucose intolerance. 7) HbA_1C was not good indicator for assessing carbohydrate metabolic state in patients with CRF. It was concluded that the serum rT_3 could be useful indicator for prediction glucose intolerance in patients with CRF. Future study for rT_3 in patients with CRF on hemodialysis and peritoneal dialysis will be needed for practical use.