실험적 타이포그래피 관점에서 본 캘리그래피에 관한 연구

박충경,정원준 커뮤니케이션디자인협회 시각디자인학회 2002 커뮤니케이션 디자인학연구 Vol.9 No.2

Recently, font and visual culture was changed in accordance with supply computer and the trend of experimental typography and replace uniform use of existing font by experimental typography and remarkably Calligraphy's use. It devise visual culture development through the new and artistic Calligraphy expression that create formative element with imply specific character involve the culture of the times Calligraphy's expression. In a restricted sense, Calligraphy is kallos(=beauty)+graphy. on the other hand Calligraphy is beautiful Calligraphy style which have the one and only of autograph. And Calligraphy style have unlimited expressional function. As different country, different character and expression of Calligraphy, in the meaning of Calligraphy is seo-ye(calligraphy) in the East, on the other hand that is beautiful handwriting which can trace the origin back to the man's speech function period in the West. But this study find out Calligraphy's identity of unique genre. And this expression is recognize Calligraphy to be unique visual language in nowaday's visual culture lead up to expression letter's role. And study calligraphy character and expression which iconography (letter that pass out of mind) with unlimited power of expression and free experimentalism.

캘리그래피의 Image Identity 효과에 관한 연구

박충경(Pak Chung-Kyoung),안석출(An Suk-Chul) 한국디자인학회 2006 한국디자인학회 학술발표대회 논문집 Vol.- No.-

한국식 초저열량 식이요법의 비만치료 효과

박원일(Won Il Park),이종협(Jong Hyup Lee),조심현(Shim Hyun Jo),백봉력(Bong Luck Paik),최충경(Chung Keung Choi),이성근(Seung Geun Lee),문한규(Han Kyu Moon),최영미(Young Mee Choi),정윤석(Yoon Sok Jung),이관우(Kwan Woo Lee),김현만(Hyeon 대한내과학회 2002 대한내과학회지 Vol.62 No.3

N/A Background: There is increasing interest in the use of a very low calorie diet (VLCD) as a treatment regimen for weight loss in obese subjects. This study was designed to investigate the effect s and safety of a traditional Korean very-low-calory diet Methods: Twelve hospitalized obese patients at Dong Eui hospital in Busan city from May 1998 to December 1998 were selected. Height, body weight, blood lipids, blood insulin level, body fat, lean body mass, subcutaneous fat and visceral fat were measured. A traditional Korean VLCD was supplied for 14 days. Results: Patient's body weight was significantly decreased from 83.8 kg to 78.6 kg, body fat from 32.2 kg to 28.6 kg, lean body mass from 32.2 kg to 28.6 kg, and BMI from 31.4 to 29.5, respectively (p <0.05). Total fat was significantly decreased from 807 cc to 659 cc, subcutaneous fat from 567 cc to 473 cc, visceral fat from 273 cc to 185 cc, respectively. However there were no significant changes in minerals. After VLCD intervention, total cholesterol was significantly decreased from 199 mg/dL to 166mg/dL, HDL-cholesterol from 42 mg/dL, to 35mg/dL, triglyceride from 158mg/dL, to 75mg/dL (p<0.05). The insulin area under the curve was also significantly decreased from 205μIU/mL·2hr to 168 μIU/mL·2hr(p <0.05). Conclusion: Above findings suggested that a traditional Korean VLCD is effective and safe for short term use in terms of reducing body fat and improving insulin resistance in obese patients. (Korean J Med 62:250-257, 2002)

인간유방암 MDA-MB-231 세포에서 청국장추출물에 의한 TNFα 발현억제

박잠언,강충경,김한복,Park, Jameon,Kang, Choong Kyung,Kim, Han Bok 한국미생물학회 2016 미생물학회지 Vol.52 No.3

청국장은 대두발효식품으로 발효 중 생성된 다양한 펩타이드가 들어 있다. 이들 펩타이드가 포함된 청국장추출물을 세포에 처리하면 세포 신호전달에 영향을 미친다. 인간 유방암 MDA-MB-231 세포에 청국장추출물을 처리해 주었을 때 세포의 성장은 농도의존적으로 억제되었다. 청국장추출물이 유방암세포의 증식을 억제하였고 암과 염증이 관련이 있으므로, 청국장추출물이 염증 유전자의 하나인 $TNF{\alpha}$ 발현의 억제 여부를 알아 보았다. 인간유방암 MDA-MB 231 세포에 청국장 추출물을 처리하면 $TNF{\alpha}$ 발현은 억제되었다. $TNF{\alpha}$ 저해제는 자가면역질환 치료제로 개발되어 있다. 본 청국장추출물도 $TNF{\alpha}$ 억제 효과가 있으므로, 이들 자가면역 질환의 치료제로 개발될 수 있을 것이다. Chungkookjang, fermented soybeans, contains diverse peptides produced during fermentation. Fermented soybean extracts containing the peptides can affect cellular signal transduction. Proliferation of human breast cancer MDA-MB-231 cells were repressed dependent on concentrations of fermented soybean extracts. Since fermented soybean extracts inhibited breast cancer cell's growth, and inflammation is related to cancer, it is determined whether it can suppress inflammatory $TNF{\alpha}$ expression. $TNF{\alpha}$ expression in MDA-MB 231 cells treated with fermented soybean extracts was repressed by that extracts. $TNF{\alpha}$ inhibitors were developed as drugs for autoimmune diseases. Since fermented soybean extracts suppressed $TNF{\alpha}$ expression, it can be developed as those drugs.

한국식 초저열량 식이요법의 비만치료 효과

박원일,이종협,조심현,백봉력,최충경,이성근,문한규,최영미,정윤석,이관우,김현만,김미경,이지현,최선정 대한내과학회 2002 대한내과학회지 Vol.62 No.3

목적 : 비만치료에 사용되는 초저열량 식이요법을 전통적인 한국음식으로 제공하여 그 안전성 및 치료 효과를 관찰하였다.대상 및 방법 : 1998년 5월부터 1998년 12월까지 동의 의료원 내과에 입원한 비만환자 12명을 연구 대상자로 선정하였다. 한국식 초저열량 식이는 14일간 다음과 같은 일정에 의해 제공되었다. 즉, 일일 1200 Kcal, 1000 Kcal, 710 Kcal, 450 Kcal, 710 Kcal, 1000 Kcal를 각각 2일, 2일, 2일, 10일, 2일 및 2일 동안 순서에 따라 제공하였다. 연구대상자들의 신장, 체중, 혈중 지질, 혈중 인슐린 농도, 체성분, 체지방을 식이요법 전후에 측정하였다. 결과 : 초저열량 식이요법 후 체성분의 변화는 체중은 83.8 kg에서 78.6 kg으로, 제지방 체중은 51.6 kg에서 50.0 kg으로, 체지방은 32.2 kg에서 28.6 kg으로, 체질량 지수는 31.4에서 29.5로 모두 유의하게 감소하였다 (p<0.05). 복부 전산화 단층촬영에서 단일 사진 면적당 총 지방량은 807 cc에서 659 cc로, 피하지방은 567 cc에서 473 cc로, 내장지방은 273 cc에서 185 cc로 모두 유의한 감소가 있었다 (p<0.05). 그러나 혈청 전해질 농도의 유의한 변화는 없었다. 식사요법 후 총 콜레스테롤이 199 mg/dL에서 166 mg/dL로, 고밀도지단백-콜레스테롤은 42 mg/dL에서 35 mg/dL로, 중성지방이 158 mg/dL에서 75 mg/dL로 유의하게 감소하였다 (p<0.05). 혈중 인슐린-곡선하 면적 (insulin-area under the curve)도 식이요법 전 205 μIU/mL·2hr에서 식이요법 후 168 μIU/mL·2hr로 유의한 감소가 있었다 (p<0.05). Background : There is increasing interest in the use of a very low calorie diet (VLCD) as a treatment regimen for weight loss in obese subjects. This study was designed to investigate the effects and safety of a traditional Korean very-low-calory diet Methods : Twelve hospitalized obese patients at Dong Eui hospital in Busan city from May 1998 to December 1998 were selected. Height, body weight, blood lipids, blood insulin level, body fat, lean body mass, subcutaneous fat and visceral fat were measured. A traditional Korean VLCD was supplied for 14 days. Results : Patient's body weight was significantly decreased from 83.8 kg to 78.6 kg, body fat from 32.2 kg to 28.6 kg, lean body mass from 32.2 kg to 28.6 kg, and BMI from 31.4 to 29.5, respectively (p<0.05). Total fat was significantly decreased from 807 cc to 659 cc, subcutaneous fat from 567 cc to 473 cc, visceral fat from 273 cc to 185 cc, respectively. However there were no significant changes in minerals. After VLCD intervention, total cholesterol was significantly decreased from 199 mg/dL to 166 mg/dL, HDL-cholesterol from 42 mg/dL, to 35 mg/dL, triglyceride from 158 mg/dL, to 75 mg/dL (p<0.05). The insulin area under the curve was also significantly decreased from 205 μIU/mL․2hr to 168 μIU/mL․2hr (p<0.05). Conclusion : Above findings suggested that a traditional Korean VLCD is effective and safe for short term use in terms of reducing body fat and improving insulin resistance in obese patients.(Korean J Med 62:250-257, 2002)

인간유방암 MDA-MB-231세포에서 peptide H에 의한 TNFα 발현 억제

성대일,박잠언,강충경,김한복,Sung, Dae Il,Park, Jameon,Kang, Choong Kyung,Kim, Han Bok 한국미생물학회 2015 미생물학회지 Vol.51 No.3

청국장은 다양한 peptide류를 포함한다. 청국장 유래의 peptide H를 인간유방암 MDA-MB-231 세포에 처리했을 때, $TNF{\alpha}$ 발현은 뚜렷하게 억제되었다. $TNF{\alpha}$에 의해 유도되는 IL6 발현 역시, peptide H에 의해 감소될 수 있음을 시사해 준다. Peptide H구조는 glucocorticoid, dexamethasone과 전혀 유사하지 않아 그들과 다른 기작으로 $TNF{\alpha}$ 발현억제에 작용할 것을 시사해 준다. Peptide H는 $TNF{\alpha}$ 발현 억제 효과가 있으므로 보다 깊이 있는 연구를 바탕으로, 류마티스 관절염, 크론병 등의 치료제로 개발될 수 있기를 기대해 본다. Chungkookjang (fermented soybeans) contains diverse peptides. Human breast cancer MDA-MB-231 cells were treated with peptide H derived from Chungkookjang, and $TNF{\alpha}$ expression in the cells was conspicuously repressed, suggesting peptide H's regulation of IL6 since IL6 is induced by $TNF{\alpha}$. The structure of peptide H was different from those of glucocorticoid and dexamethasone, suggesting different mechanisms of $TNF{\alpha}$ expression suppression. Peptide H which reduces $TNF{\alpha}$ expression can be developed as drugs for cancer, rheumatoid arthritis and Crohn's disease, after more investigation.

국내 영화포스터의 로고타입에 나타난 캘리그래피의 유행성

서현석(Hyun-Seok Seo),고윤예(Yun-Ye Ko),박충경(Chung-Kyoung Park) 한국디자인학회 2003 한국디자인학회 학술발표대회 논문집 Vol.- No.-

한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.