http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
고형암의 골수 전이에 대한 병리학적 검색 및 임상적 의의
김재유,박승만,이안희,문한림,김춘추,김훈교,오세정,이경식,이성용,조석구 가톨릭중앙의료원 가톨릭암센터 1997 암심포지움 Vol.- No.1
저자들은 암환자 중 병기별 분류를 위하여 골수천자와 생검을 실시한 80예를 대상으로 골수 전이유무, 조직면역화학 염색에 의한 부가적인 전이 발견율, 골 동위원소 주사검사상 골 전이 소견, 일반적인 검사 소견등을 분석하였다. 1) rm 결과 80예 중 7예(8.8%)가 고식적인 도말표본 및 생검표본에서 골수에 전이된 것으로 판명되었으며, 위암 2예(2/35, 5.7%), 유방암 2예(2/27, 7.4%), 소세포 폐암, 전립선암, 신장암 각 각 1예이었다. cytokeratin, EMA 또는 NSE에 의한 조직면역 화학 염색을 실시하여 미세전이를 발견하여 보고자한 38예 중 고식적인 골수검사 표본에서 전이가 발견된 7예에서만 양성으로 판독되어 예민도가 더 증가하지는 않았다. 골 동위원소 검사에서 골 전이가 있는 것으로 판독된 19예 중 6예(31.6%)와 없는 것으로 판독된 61예 중 1예(1.6%)에서 골수전이가 있어 골전이와 골수전이는 밀접한 관계가 있음을 보였다. 골전이와 골수전이가 동시에 있었던 6예는 최소한 7군데 이상의 골전이가 있었으며 모두 천자 부위인 골반골에 전이되어 있었다. 이로써 양성율을 높이기 위해서는 적절한 표본이 중요함을 알 수 있고 여러 곳에서 채취할 것과 특히 임상적으로 골의 변화가 있는 부분을 천자할 것이 권고된다. 또한 각 예마다 골수도말 표본, 응괴절편, 생검표본 모두를 시행함이 양성율을 높이는데 필요하다고 본다. 2) 골수에 미세전이가 있는 환자의 말초혈액 소견과 전이가 없는 환자의 그것과는 크게 다른 점은 없었으나 골수소견으로는 미세전이 때 동반할 수 있는 골수섬유증을 28.5%에서 발견할 수 있었다. 3) 골수전이가 있었던 환자의 중앙생존 기간은 3.8개월이었고, 골수의 미세전이는 원격전이나 조기재발을 예견할 수 있는 등 예후 측정에 매우 유용하다. 4) 미세전이를 찾기위하여 immunofluorescent 항체 분석, 골수배양, PCR 및 immunocytopathology, clonal growth, flow cytometry 등 여러 가지 방법의 시도가 요구된다.
고재철,김재유 한국환경기술학회 2023 한국환경기술학회지 Vol.24 No.6
Recently, there have been a lot of complaints of urban odor from industries and sewers and the solution to reduce odor should be established. There are a couple of methods, such as dynamic olfactometry and e-noses, to measure odor concentration. In this paper, odor-related 100 surveys were done at 10 urban areas near industrial complex around June 2022. The purpose of this paper is to compare ammonia (NH3) measurement and maloder survey results and to figure out how to reduce the maloder. The survey results were compared with ammonia (NH3) concentration at the corresponding area because hydrogen sulfide (H2S) was hard to measure. Citizens in Apartment Area 2 could smell manure although NH3 was not measured in Apartment Area 2. Therefore, it can be suggested that manure smell in Apartment Area 2 was resulted from the non-sewage facility. The surveys related to odor complaint report were also done at those areas, and citizens in the surveyed area generally thought that maloder regulation was needed.
姜忠南,金聲俊,金在油 최신의학사 1971 最新醫學 Vol.14 No.11
The result of physical therapy for the 72 cervical disorders are reported in the analysis of clinical symptoms and X-ray findings including strain injury and mild organic bony or disc changes. The patients are consist of the 54 cervical strain, seven osteoarthritis, six cervical disc degenerations, three subluxations, one each of the rheumatoid arthritis and congenital anomaly. The cervical strain is proved by the loss of normal lordotic curvature of the cervical spine on X-ray examination. The routine daily treatment was 20 minutes of hot pack, three minutes of ultrasound, 0.5-4.0 W/Cm2, and 15 minutes of cervical traction by 15-25 Lbs. weight for eight weeks. Also they had received the mild analgesic or sedatives for first one week. 1) The sex incidence of male and female was 2:3 and the age distribution was relatevely even from ten ager to 70 years old. 2) Their symptoms are local tenderness (36.2%), limitations of motion (18.5%), radiating pain into upper extremity(16.9%), sensory changes (6.9%), motor weakness, vertigo, dizziness, occipital migrain headache and decreased D.T.R. of the upper extremity. 3) The 54 cervical strain was analized in X-ray examination for its abnormal locations. The hyperextension strain with abnormal curve at C4_5 is twice more than hyperflexion injury of C5-6. 4) The patient responded well to the treatment and 66 out of 72 become symptom free in four weeks. Three cases are needed for eight weeks of treatment to recover and rest of three cases have had Thomas collar or neck braces. Clinically the subjective symptoms are important and more helpful in evaluation of the patients than objective symptoms such as X-ray finding which is hard to make definite diagnostic criteras. Also the continuation of treatment is valuable to obtain the good result in sufficient explanation of the charactor of disease to them and make them confidence and cooperate fully.
코의 Angiocentric Immunoproliferative Lesions(AILs)
한지연(Ji Youn Han),김재유(Jae You Kim),이연수(Youn Soo Lee),정수미(Su Mee Chung),김민식(Min Shik Kim),윤세철(Sei Chul Yoon),김훈교(Hoon Kyo Kim),조승호(Seung Ho Cho),김병기(Byung Kee Kim),경식(Kyung Shik Lee),김동집(Dong Jip Kim) 대한두경부종양학회 1996 대한두경부 종양학회지 Vol.12 No.1
Lymphomatoid granulomatosis, polymorphic reticulosis, midline malignant reticulosis, or lethal midline granuloma have similar histologic features of an angiocentric and angiodestructive lymphoreticular proliferation representing the same nosologic entity. The term 'angiocentric immunoproliferative lesion' (AIL) was proposed by Jaffe, Costa, and Martin. The malignant potential of AILs is originally uncertain, but the facts that AILs have a relatively short survival, and most of them usually progress to an overt malignant lymphoma and survival is inversely proportional to the large, atypical lymphoreticular cells suggest that AILs are malignane. We experienced 17 AILs in nose during 16-year period and retrogradely analized them to recognize the problems in the diagnosis and to establish the further therapeutic strategies. The results were as follows; Twelve of total 17 patients who had diagnosed as histologic grade 1 and 2 had received radiation therapy as an initial treatment and the complete response rate was 91.7%(11/12), but 6 out of 11 had local recurrence and 5 had progress to overt maligant lymphoma within 2years. Three patients with the histologic grade 3 and 2 with unclear histologic grade had received CHOP chemotherapy and there was 1 case with complete response. Two patients with unclear histologic grade had been proved to be malignant histiocytosis by bone marrow biopsy during the clinical course. The overall duration of survival was 2 - 119 months and the 5-year survival rate was 71.9%. And the achievement of initial complete response was the most important prognostic factor of overall survival(P=0.006). Our results suggest that the treatment strategy according to the histologic grading scheme is efficient and more aggressive combination chemotherapy may be necessary to achieve complete response in patients with histologic grade III and II, because most of them progress to overt malignant lymphoma during its process.