만성 전두동 전벽 골수염 환자의 수술 후 발생한 전두동 전벽 결손을 TutoplastⓇ(Allograft Cancellous Bone Chip)를 이용하여 치험한 1예

곽명수,조주완,전석원,김민정 대한이비인후과학회 부산,울산,경남 지부회 2014 임상이비인후과 Vol.25 No.1

Osteomyelitis is a severe infection of bone that can arise from a variety of mechanisms. Osteomyelitis is an acute, subacute, or chronic inflammatory process of the bone, secondary to pyogenic bacterial infection, which differs according to patient’s age and infection mechanism. Treatment requires isolation of the pathogens, significant debridement for removal of all infective and necrotic material, and then bony and soft tissue reconstruction. We recently experienced a case of frontal sinus anterior wall defect caused by chronic frontal osteomyelitis in a 62-year-old male patient. The frontal sinus anterior wall defect was repaired using TutoplastⓇ (allograft cancellous bone chip).

기업성과지표로서 EVA의 유용성에 관한 연구

남명수 ( Myung Soo Nam ),곽용신 ( Yong Sin Kwak ) 한국생산성학회 2011 生産性論集 Vol.25 No.3

This study analyzed the usability of economic value added(EVA) as a company performance indicator by utilizing non-financial data of the stock market from 2000 to 2009. We investigated whether EVA provides useful information for MVA, which represents company performance from the executive`s position, and for the average rate of return and excessive abnormal return, which represent performance from the investor`s position. Analyses showed that EVA`s explanation power for MVA is higher than other accounting performance indicators such as FCF, ROA and ROE, which revealed the fact that it is more valuable as a company performance indicator. Also, portfolios with positive EVA showed higher average rate of return and excessive abnormal return, which are performance indicators from the investor`s position, than portfolios with negative EVA. During the analysis period, the rate of return and cumulative abnormal return(CAR) of portfolios with continuously positive EVA were higher. Therefore, it is judged that EVA provides useful information for MVA, the rate of return and CAR.

이슬람 금융의 발전사적 고찰과 우리의 대응전략

남명수(Myung soo Nam),곽용신(Yong sin Kwark) 한국경영사학회 2009 經營史學 Vol.52 No.-

1990년대 후반의 IMF와 최근의 금융위기는 기존 서구식 금융에 대한 불신의 확산 계기가 되었다. 때를 같이하여 서구식 금융과는 달리 이슬람 금융은 눈에 띄는 성장을 하였으며, 이에 세계 금융권에서는 ‘이슬람 금융’이 이슈화되기 시작하였다. 이슬람 금융은 서구식 금융의 핵심이라 할 수 있는 ‘이자’가 금지되며, 실물의 거래를 수반해야하는 특성이 있다. 따라서 서구식 금융과는 다른 독특한 금융상품을 발전시키게 된다. 이러한 이슬람 금융의 도입 필요성은 고유가로 인한 풍부한 오일 머니의 활용, 기업의 사회적 책임, 저렴한 금융비용 및 투자의 안정성 측면에 찾을 수 있을 것이다. 이슬람 금융의 발전사적 특성을 살펴보면 1970년대 이전에는 이슬람 금융에 대한 기본적 논의와 실험적 도입, 1990년대 중반 이전까지는 체제의 정비와 다양한 금융상품의 개발, 소매금융 상품 위주의 거래, 1990년대 중반 이후부터는 이슬람 금융의 도매상품 거래의 활성화 및 국제화로 정리 할 수 있다. 이슬람 금융의 발전사적 특징 및 선진 이슬람 금융의 도입사례를 검토한 결과 이슬람 금융에 대한 국민적 이해가 수반되지 않은 현 상황에서는 이슬람 금융을 성공적으로 도입한 국가와 협력체계를 강화하여 간접적으로 도입한 이후 점진적인 도입이 필요하며, 금융 상품에 있어서도 소매 금융보다는 도매 금융을 우선적으로 도입하는 것이 보다 바람직할 것이다. 또한 관련 법률제도의 정비, 이슬람 금융 전문가의 육성 등 기본 인프라구축이 필요하며, 경제와 문화적 측면에서의 이슬람 국가와의 협력체계 강화가 필요할 것이다. The state of affairs in western finance caused by the recent global financial crisis has attracted world interest to Islamic finance which is evolving rapidly based on affluent oil money. Islamic finance is moving toward the internationalization phase through retail and wholesale finance phase, starting from criticism against interest based finance in 1940s. In simple definition, Islamic finance is financial system that conforms to “Sharia”, which refers to a code of law or divine injunctions that regulate the conduct of human beings in their individual and collective lives. Islamic finance includes the spot transaction in financial transaction and prohibits ‘interest’ which is the core of western finance. The introduction of Islamic finance will allow us to use the affluent oil money for low cost and we can expect relatively high profit and stable investment in comparison with conventional financial system. Islamic finance will also make it possible to diversify financial portfolio which was focused on US and Europe and it has advantage of complying with SRI(socially Responsible Investing) which has become the center of attention recently. We need to approach Islamic finance with caution despite its many advantages because Islamic finance which is based on Islam religion has emotional and systemic difference from korean financial system. So we need the understanding and interest about Islamic finance and also need to reorganize the related law and system for efficient introduction of Islamic finance. We also need experts who can manage Islamic financial products. We will need to introduce Islamic finance gradually by selecting low-risk and high profit financial product.

고식적 수술적 치료 후에도 지속되는 난치성 만성 상악동염 환자군에서 변형된 경하비갑개 개방확장술의 임상적 효용성

천경훈,곽명수,양지호,김민정,김영훈,이원용 대한이비인후과학회 2013 대한이비인후과학회지 두경부외과학 Vol.56 No.9

Background and Objectives Despite aggressive medical therapy and previous endoscopic sinus surgery, there are a subset of patients suffering from recalcitrant, persistent chronic isolated maxillary sinusitis which results from impaired mucocilliary clearance caused by long-standing inflammation. The corresponding patients underwent our newly devised Modified Inferior Meatal Mega-Antrostomy (Modified IMMA). The objective of this study was to review the clinical efficacy and complication after Modified IMMA in patients who had suffered from intractable maxillary sinusitis after endoscopic sinus surgery. Subjects and Method Fourteen patients suffering from recalcitrant chronic isolated maxillary sinusitis underwent Modified IMMA between May 2010 and April 2013. The mean follow-up period was an average of about 13 months and regular intervals of postoperative 3-, 6-, 9-, 12-months were set. A retrospective review was performed to analyze the preoperative & postoperative Visual Analogue Scale score (VAS score) and Lund-Kennedy endoscopy score at each interval. VAS scores and endoscopic findings were processed statistically at the time of third postoperative month. The exclusion criteria were an obstructed ostiums, osteitis, systemic disease such as Ig A/G immunodeficiency, primary ciliary dyskinesia. Results The postoperative VAS scores and Lund-Kennedy scores, when compared with those prior to Modified IMMA, decreased from 16.5 to 2.5 and 5.0 to 1.0, respectively. Also, there was no serious complication or recurrence associated with the procedures. Conclusion Our newly devised Modified IMMA could be a much effective option for surgical treatments in patients with recalcitrant chronic isolated maxillary sinusitis.

Bambusae Caulis in Taeniam Applicable for Medical Indications Associated with Inflammation

최효재,곽유경,이지연,권민정,최준용,주명수 한의병리학회 2023 동의생리병리학회지 Vol.37 No.1

Jukyeo (竹茹; Bambusae Caulis in Taeniam: BCT) is an herbal medicine made from the inner part of the bamboo stem of Phyllostachys nigra Munro var. henonis Stapf ex Rendle or Phyllostachys bambusoides Siebold et Zuccarini. Although medical literature published in China and Korea decades ago introduced BCT as a remedy for reducing vomiting, fever, and hematemesis, decoctions containing BCT as a main herb (君藥) in Korea have been approved only for treating neurologic symptoms. Here, we discuss the anti-inflammatory function of BCT. Combined with the clinical usage of a BCT-containing decoction in treating inflammatory diseases in Japan, we raise the possibility of repurposing the BCT-containing decoctions for treating inflammatory diseases. The anti-inflammatory activity of BCT was mainly assessed by using RAW 264.7 cells. The regulation of NF-κB, Nrf2 and A20 activities was determined by western blot and quantitative RT-PCR. The list of decoctions containing BCT currently approved in Korea was obtained from the Korean Ministry of Food and Drug Safety (KFDA). BCT suppressed the activity of pro-inflammatory factor NF-κB elicited by LPS, activated an anti-inflammatory factor Nrf2, and induced A20 that is known to block several inflammatory pathways simultaneously, suggesting that BCT can suppress inflammation via at least 3 different pathways. KFDA approved 11 decoctions containing BCT as a major herb, including Gamiondam-tang (加味溫膽湯; GOT), for treating neurologic disorders. Interestingly, Jukyeoondam-tang (竹茹溫膽湯; JOT), whose composition is almost identical to GOT except for one herb, has been used to treat inflammatory pulmonary disorders including Covid-19 pulmonary infection in Japan Given the anti-inflammatory function of BCT evidenced by medical literature and experimental results and the clinical usage of JOT in treating inflammatory pulmonary disorders, we suggest a repurposing and extension of the BCT-containing decoctions approved in Korea to treating inflammatory diseases.

Carrier dynamics in ZnO/ZnMgO multiple quantum well structures with different well widths grown on ZnO substrates

이송매,권봉준,곽호상,김려화,조용훈,박영신,한명수,박영식 한국진공학회 2009 한국진공학회 학술발표회초록집 Vol.37 No.-

유양동에 발생한 거대 선천성 진주종 1예

이진오,천경훈,곽명수,김영훈 대한이비인후과학회 부산,울산,경남 지부회 2012 임상이비인후과 Vol.23 No.2

Congenital cholesteatoma is a rare lesion of the temporal bone. It accounts for only 2 to 5% of all cholesteatoma, though that number is throught to be on the rise due to improved imaging techniques. The diagnosis of a congenital cholesteatoma includes a pearly white mass behind an intact tympanic membrane without history of otitis media, otorrhea, or otological surgical procedure. Congenital cholesteatoma may develop in various temporal bone sites including the middle ear cavity, petrous apex, cerebellopontine angle, external auditory canal and mastoid process. The most frequent site of origin is the middle ear cavity, whereas the rarest is the mastoid. The clinical presentation is usually an symptomatic white mass behind an intact tympanic membrane. The congenital cholesteatoma that originates in the mastoid is more difficult to diagnose due to variable clinical presentation. We recently experienced a case of congenital cholesteatoma with facial palsy in 33 year old male patient who showed normal tympanic membrane without prior history of ear disease and otologic surgical procedure. We report this case with brief review of the literatures

선박에서 발생되는 수중 소음이 해양 환경에 미치는 영향

주해지,박정탁,곽명수,곽경민,김근태,임재완,한승관,문은향,한민이,정주암,김도영,한원희 해양환경안전학회 2015 해양환경안전학회 학술발표대회 논문집 Vol.2015 No.11

전이개 농양의 원인 균주 분석 및 항생제의 선택

권민한,이진오,천경훈,곽명수,양지호,박상규 대한이비인후과학회 2012 대한이비인후과학회지 두경부외과학 Vol.55 No.10

Background and Objectives Infection of congenital preauricular fistula leads to preauricular abscess. Generally, the treatment for preauricular abscess is focused on subsiding abscess. Although incision & drainage is major point of therapy, the study of bacterial species and antibiotics for preauricular abscess is scant in literature. So, we investigated the most common species that cause preauricular abscess and the choice of proper antibiotics by using the databse available from the last 10 years. Subjects and Method Our studies, from January, 2000 to December, 2010, included 86 patients in total (all in patients & out patients). We performed a retrospective review of bacterial species and culture analysis of each preauricular abscess. Results In this study, it was shown that most common pathogens causing preauricular fistula infection were Staphylococcus (27.9%), Enterococcus (9.3%), streptococcus and Klebsiella (5.8%) and Peptostreptococcus (4.6%). And Amoxicillin/cavulanate, Ciprofloxacin, Clindamycin had excellent effects of minimal inhibitory concentration through multiple pathogens. Conclusion The choice of antibiotics for preauricular abscess will be targeted on Staphylococcus, Enterococcus, Streptococcus and anaerobic infection. Amoxicillin/clavulanate or Ciprofloxacin are the most effective antibiotics.

선생님, 우리 선생님

이정숙,조영수,류인감,황금희,변민승,곽명수,이완세 샘터사 2002 월간 샘터 Vol.33 No.6