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황봉운,이윤세,이병주 대한이비인후과학회 부산,울산,경남 지부회 2012 임상이비인후과 Vol.23 No.1
자가 분열능력, 분화능력,면역조절 기능 때문에 줄기세포는 임상의 다양한 분야에서 장기 및 기관의 손상에 대한 기능회복을 목표로 활발한 연구가 진행되고 있다. 최근 이비인후과 질환과 관련해서도 줄기세포에 대한 많은 연구가 이루어지며 다양한 성과들과 함께 일부에서는 임상 적용을 위한 단계에 도달하였다. 향후 기존의 치료법에 더하여 줄기세포를 이용한 치료가 환자들의 삶의 질을 향상시킬 수 있으리라 기대된다. 하지만 임상에 적용하기 위해서는 아직 넘어야 할 문제들이 남아있다. 줄기세포 이식에 있어 낮은 생착율의 문제, 생착한 곳에서 원하는 세포로의 분화문제, 그리고 인접 세포들과의 상호작용, 면역학적 거부반응 등은 앞으로 연구를 통해 해결해 나가야 할 점이다. 또한 치료에 따른 기능적, 해부학적 치료 결과를 객관적으로 판단할 수 있는 방법의 개발과 임상적으로 줄기세포를 사용하는데 따른 제도적 장치를 마련하는 것도 해결해야 할 숙제이다.
정대한,서미경,강호민,이준석,박문서,여승근 대한이비인후과학회 부산,울산,경남 지부회 2011 임상이비인후과 Vol.22 No.1
Background and Objectives:Stress is defined as excited state resulted from interaction of body and mind. It is subjective notion in that the amount of stress can be different in each person from same event. Nevertheless, there have been many studies to find objective measure to assess stress and many questionnaires have been developed. In our study, we tried to measure the amount of stress of representative diseases of Otorhinolaryngology and head and neck surgery using ‘Daily Hassless Scale’, one of well known stress questionnaire. Materials and Methods:276 people including 36 people of normal control, 20 patients of chronic sinusitis, 20 of laryngopharyngeal reflux, 20 of obstructive sleep apnea, 19 of nasal septal deviation, 20 of facial palsy, 20 of vocal nodule, 21 of allergic rhinitis, 20 of hearing disturbance, 20 of dizziness, 21 of tinnitus, 23 of chronic otitis media and 16 of preauricular fistula were enrolled to our study. They were made to fill up the questionnaire form when they visited our clinic. The questionnaire is composed of 36 questions and each is 4 point scale. We statistically compared total stress score and health related score. Results:Laryngopharyngeal reflux and allergic rhinitis patients group showed significantly higher stress score than control group (p=0.003). Laryngopharyngeal reflux, facial palsy, vocal nodule, allergic rhinitis patients group showed significantly higher score than control group in sum of four health related questions (p=0.000). Conclusion : Laryngopharyngeal reflux, facial palsy, vocal nodule, allergic rhinitis patients group were suffered from higher stress than other otolaryngology disesases and these shoud be considered during managing patients.
술후성 협부 낭종에 대한 임상적 분석 : 10년의 경험
이재훈 대한이비인후과학회 부산,울산,경남 지부회 2012 임상이비인후과 Vol.23 No.1
The aim of this study was to evaluate the clinical analysis of postoperative cheek cyst for past 10 years and causes of revision surgery. Subjects and Methods:The study design was a retrospective clinical series. We reviewed the medical records of 45 cases (43 patients : both cases in two patients) with postoperative cheek cyst who were diagnosed and treated from 1999 to 2009. Results:The patients underwent middle and/or inferior meatal antrostomy with or without Caldwell-Luc operation. All patients were followed at least for more than 24 months after surgery, and revision surgeries were noted in 9 cases (20%). Of the 9 cases in revision surgery, the obstruction of inferior meatal antrostomy site in 7 cases and remained cyst from multiple septated cysts in 2 cases were showed. Conclusion:In order to avoid of revision surgery for postoperative cheek cysts, we should carefully review of paranasal computed tomography scan findings such as bulging state of the cyst into the inferior meatus and presence multiple septated cysts. 본 연구를 통해 술후성 협부 낭종에 대한 재수술의 분석을 통해 두가지 사항에 대해 생각할 수 있었다. 첫째, 다발성 낭종에 대한 가능성을 염두하고 세심하게 부비동 단층촬영영상에 대한 관심을 가져야 할 것으로 생각된다. 둘째, 술후성 협부 낭종의 하비도내에서 돌출형태를 확인한후 하비도내로 충분히 돌출된 낭종은 하비도 접근으로 해결이 되면 수술 후 배액공의 유지가 잘 될 가능성이 많으나 낭종이 돌출되지 않은 경우 시간이 지남에 따라 배액공의 폐쇄될 가능성을 염두 해야 할 것으로 생각된다. 만약 하비도 배액공의 폐쇄 가능성이 많은 경우 본 연구에서처럼 T자 형태의 튜브를 위치시킴으로써 폐쇄의 가능성을 줄일 수 있을 것으로 생각된다.
호산구성 중이염을 동반한 알레르기성 진균성 부비동염 1예
김이혁,고재진,손호진,신승헌 대한이비인후과학회 부산,울산,경남 지부회 2012 임상이비인후과 Vol.23 No.2
Eosinophilic otitis media (EOM) is a middle ear disease with extremely viscous mucoid effusion containing numerous eosinophils associated with allergic rhinitis and bronchial asthma. EOM is extremely unresponsive to conventional treatment for the common type of otitis media. EOM patients have the deterioration of the bone conduction hearing level, due to the inflammatory mediators released from inflammatory cells could enter the inner ear. One of the most effective treatments for esoinophilic inflammation is the administration of a steroid. Although EOM is commonly associated with nasal polyps, their relation to allergic fungal sinusitis is not reported. Hence we report a case of EOM proceeded with allergic fungal sinusitis with a review of literature.
혈청학적 양성 톡소플라즈마 림프절염의 세침흡인세포검사와 절개생검 결과
박준호,이경규,이영민,조헌포 대한이비인후과학회 부산,울산,경남 지부회 2012 임상이비인후과 Vol.23 No.2
Toxoplasmosis is a common cause of cervical lymphadenopathy and histopathological specimens needed for establishing diagnosis, the diagnosis of toxoplasmic lymphadenopathy should always be confirmed by isolation of the parasite or by serologic test. The use of fine needle aspiration cytology (FNAC) in the investigation of lymphadenopathy is minimally invasive and has become an worldwide acceptable technique. We compare the results of FNAC and excisional biopsy in seropositive toxoplasmic lymphadenitis, to determine the importance of excisional biopsy and serologic test for toxoplasmosis. Materials and Methods:A retrospective chart review of 12 patients (7 underwent only FNAC, 4 underwent both FNAC and excisional biopsy, remaining 1 was only excisional biopsy case) was carried out. Results:Only 36.3% of FNAC group match toxoplasmic lymphadenitis, but excisional biopsy group is reliable to toxoplasmic lymphadenitis. Conclusions:When FNAC result of solitary cervical lymphadenitis is obscure, the excisional biopsy and serologic test for toxoplasma is always helpful for establishing diagnosis of toxoplasmosis.
손희영,김대우,김진평,안성기,박정제,허동구,전시영 대한이비인후과학회 부산,울산,경남 지부회 2010 임상이비인후과 Vol.21 No.2
Risk Factors Caused by Underlying Diseases in Geriatric Patients during Endoscopic Sinus Surgery
이정훈,윤영호,조규섭,윤빛나 대한이비인후과학회 부산,울산,경남 지부회 2010 임상이비인후과 Vol.21 No.2
Schwannomas are neurogenic neoplasm rarely found in the sinanasal tract. Schwannoma of nasal septum was first described Bogdasarian and Stout in 1943 and 24 additional cases with adequate clinical pathological information were subsequently reported in the literature. We herein report a rare case of schwannoma of nasal septum with the literature review. (J Clinical Otolaryngol 2010;21:270-273)