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김종윤,서정기,고광욱,최용,정해일,윤회상,김용일 대한신장학회 1985 Kidney Research and Clinical Practice Vol.4 No.1
The following results were obtained by the retrospective clinicopathological analysis of 20 cases of membranous nephropathy associated with hepatitis B antigenemia in children. 1) The mean age of onset was 5 years 9 months, and male to female ratio was 18 to 2 with marked male preponderance. 2) Hepatitis Be antigen was positive in all 17 cases tested, reasonably high enough to speculate that the subepithelial deposit of the membranous nephropathy is related to hepatitis Be antigen. 3) Edema(65%), edema and gross hematuria(30 %) were the most common presenting symptoms. 4) 19 out of 20 cases showed nephrotic syndrome during the clinical courses, and 8 cases(40%) showed hypocomplementemia. 5) Pathologically, hepatitis B virus antigenemia associated membranous nephropathy was different from the idiopathic membranous nephropathy by its presence of election dense deposits in the sites other than subepithelial portion. 6) Steroid did not provide any prolonged beneficial effect. Because there is an increased risk of persistent hepatitis B virus antigenemia with steroid treatment, steroid seems not be recommended in hepatitis B virus antigenemia associated membra- nous nephropathy at present.
김종윤,김대현,배상은,박태홍 한국공업화학회 2016 한국공업화학회 연구논문 초록집 Vol.2016 No.0
고온의 부식성이 높은 물질의 점도, 전기전도도, 밀도, 표면장력 등 물성 측정은 원자력 산업 등 다양한 공정에서 중요하다. 하지만, 일반적인 상용 표면장력 측정기를 사용하는 경우, 부식성이 높은 500도 이상의 고온의 용융염의 표면장력을 측정할 수 없다. 따라서, 특별히 고안하여 자체 제작한 동적표면장력 측정장치를 이용하여 고온 용융염의 표면장력을 측정하였다. 0.3mm 이하의 직경을 갖는 스테인리스 재질의 특수 모세관을 주문제작하였고, 질량유량제어기와 미분형차압센서를 이용하여 기포 내외부의 압력의 차이를 측정하였다. LabView 프로그램을 이용하여 스테핑모터 구동, 최대기포내압 측정 데이터 입력 및 출력에 활용하였다. 초순수를 이용하여 동적표면장력 측정장비의 교정 및 정확도를 확인하였다. 본 논문의 장비는 극한 환경에서의 용액에 대한 동적표면장력을 측정할 수 있기 때문에 향후 특수 산업분야의 활용성이 우수할 것으로 기대하고 있다.
김종윤,정혜문,이병권,민필기,최의영,윤영원,홍범기,임세중,권혁문 연세대학교의과대학 2016 Yonsei medical journal Vol.57 No.1
Purpose: Left ventricular (LV) filling pressure affects atrial fibrillation (AF) recurrence. We investigated the relationship betweendiastolic dysfunction and AF recurrence after cardioversion, and whether LV filling pressure was predictive of AF recurrence. Materials and Methods: Sixty-six patients (mean 58±12 years) with newly diagnosed persistent AF were retrospectively enrolled. We excluded patients with left atrial (LA) diameters larger than 50 mm, thereby isolating the effect of LV filling pressure. We evaluatedthe differences between the patients with (group 1) and without AF recurrence (group 2). Results: Group 1 showed increased LA volume index (LAVI) and E/e’ compared to group 2 (p<0.05). During a mean follow-upperiod of 25±19 months, AF recurrence after cardioversion was 60.6% (40/66). The area under the receiver operating characteristicscurve of E/e’ for AF recurrence was 0.780 [95% confidence interval (CI): 0.657–0.903], and the optimal cut-off value of the E/e’was 9.15 with 75.0% of sensitivity and 73.1% of specificity. A Kaplan-Meier survival curve showed that the cumulative recurrencefreesurvival rate was significantly lower in patients with higher LV filling pressure (E/e’>9.15) compared with patients with lowerLV filling pressure (E/e’≤9.15) (log rank p=0.008). Cox regression analysis revealed that E/e’ [hazards ratio (HR): 1.100, 95% CI:1.017–1.190] and LAVI (HR: 1.042, 95% CI: 1.002–1.084) were independent predictors for AF recurrence after cardioversion. Conclusion: LV filling pressure predicts the risk of AF recurrence in persistent AF patients after cardioversion.