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淫羊藿 水抽出物이 생쥐의 면역글로불린 및 Cytokine 생성에 미치는 영향
최용덕,이창현,이상룡,육상원,김정훈,우원홍,이광규 대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.2
This present study was carried out to investigate the body weight-regulatory effects of several herbs(Plantaginis Semen; PLS, Zeas Stigma; ZS, Sophorae Radix; SR) in high fat diet-induced obese rats. Control group rats were fed with high fat diet and administered normal saline for 8weeks. Experimental groups rats were fed with high fat diet and administered extract of 3 herbs each other for 8weeks. And observed that, body weight of rats and total cholesterol, triglyceride, free fatty acid, total lipid, phospholipid, high density lipoprotein(HDL)-cholesterol, low density lipoprotein(LDL)-cholesterol in serum of rats, and glucose, insulin of rats. The results were as follows: There were significant decrease of serum total cholesterol level in PLS group and ZS group. There were significant decrease of serum total lipid level in PLS group, ZS group and SR group. There were significant decrease of serum phospholipid level in ZS group. There were significant decrease of serum LDL-cholesterol level in ZS group. There were significant decrease of serum glucose level in PLS group and ZS group. According to above mentioned results, Plantaginis Semen, Zeas Stigma and Sophorae Radix were expected to be applied to the prevention or treatment of obesity and its complications. Key word : Body weight-regulation,Obesity, Plantaginis Semen(車前子), Zeas Stigma(玉米□), Sophorae Radix(苦蔘)
최용덕,하정희,김미경 한국체육사학회 2023 체육사학회지 Vol.28 No.2
This study is based on data such as newspapers, magazines, memoirs, autobiography, photographs, and Suwon Gwanggyo Museum investigation to systematically analyze Min Gwan-sik’s life and sports activities. The result is: Min Kwan-sik is a person with a naturally strong temperament, and has demonstrated outstanding ability in table tennis since childhood. After his older brother, a national activist, passed away, he entered the political world and formed a special relationship with Park Chung-hee. As a sports administrator, Min Kwan-sik served important positions such as the president of the Korea Sports Association, the minister of education, and the head of an athletics organization, laying the groundwork for the development of sports in Korea and contri buting to the establ i shment of physical and human infrastructure. Hi s sports promotion policy was successfully promoted based on nationalistic sports elitism and the idea of the people. In this way, Min Gwan-sik played a decisive role in achieving modernization by breaking away from the pre-modern characteristics of the Korean physical education and sports field, and his achievements are worthy of being recognized as the father of the modernization of Korean sports.
柳泳秀,姜亨源,李光揆,崔用德 대한동의병리학회 1999 동의생리병리학회지 Vol.13 No.1
전 세계적으로는 1700만에서 2500만명이 알츠하이머병 환자가 있고 실제로 85세이상의 인구중 약 50%가 알츠하이머병인 것으로 알려져 있다. 알츠하이머형 치매의 경우 腦에서 大腦皮質의 萎縮, 副交感神經과 다른 神經細胞의 退化, neurofibrillary tangles(신경원섬유농축제, NFTs)의 存在, senile plaques(노인반)의 蓄積과 같은 4가지 구조적변화가 나타나며 neurofibrillary tangles와 senile plaques는 알츠하이머형 치매의 지표로 인식되고 있다. 그러나 지금도 알츠하이머병에 대한 發病原因이 不分明하여 硏究를 계속 進行 중이다. 특히 腦의 構造에서 非正常的으로 발견되는 두 가지 構造인 neurofibrillary tangles와 senile plaques가 무엇이며, 이러한 구조가 어떻게 만들어졌는가를 중심으로 활발히 硏究가 이루어지고 있다. 이에 著者는 이미 腦 代表的인 退行性 疾患으로 알려진 알츠하이머형 치매에 나타난 病理的 所見과 最近 發表된 硏究를 中心으로 韓醫學的인 病因病機를 比較 分析하였다. 痴매의 老化와 遺傳的 要因이 韓醫學의 臟腑的으로는 腎虛와 밀접한 關係를 맺고, 베타-아밀로이드와 tau 단백질과 같은 뇌속의 비정상적인 plaque는 痰濁과 瘀血 등의 韓方的 病理産物과 유사한 의미를 가지므로 실제 임상에 있어서도 베타-아밀로이드와 tau 단백질을 除去하는 서양의학적인 原因除去 治療法과 韓醫學的인 腦와 五臟과 關係에서 補腎法과 祛痰化瘀法을 竝行한다면 보다 나은 효과가 있을 것으로 思料된다. Through study of eastern and western records of dementia, the result were obtained as follows ; 1. The chief expression and pathogenic change of alzheimer's disease, the typical degenerative disease of brain, is overall cerebrum atropy, cerebral ventricular enlargement, senile plaque and neurofillary tangles(NFTs) etc. 2. The etiology of dementia is genetic factors, immunologic factor, virus, toxic substance and cephalic trauma etc. Among the rest, the genetic factor is being studied vigorously. 3. The typical substance of expired dementia brain cell are β-amyloid and tau protein. The accumulation of β-amyloid is known as the cause of senile plaque and amyloid angiopathy. The neurofillary tangles are known as substance made through the process of hyperphosphate of tau, a protein of neuronal cell frame. 4. From the oriental medical point of view, the defficiency of the kidney, liver and heart is the basic internal cause of dementia DamTak(痰濁), Blood stasis(瘀血), Chiljung(七情), Fung(風) and Hua(火) are exterior cause factor. Among the rest, the defficiency of the kidney is the most cause factor. 5. From the oriental medical point of view, the aging and genetic factor of dementia have much connection with the defficiency of kidney. Abnormal plaques of the brain such similar to the estern pathogenic substance such as Domtak(痰濁) and Blood stasis(瘀血). Like this, as the result of the study about the pathogenic subsntce of dementia is being studied vigorously, to treat dementia, etiologic factor-β-amyloid, tau protein-removal therapy and the eastern Bushen(補腎) therapy and Qutanhuayu(祛痰化瘀) therapy is likely to help the better clinical application.