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Ning-Ning Dou,Hao-lin Wang,Shao-Zhen Hu,Zheng-Nan Huang,Jun Zhong,Shi-Ting Li 대한척추신경외과학회 2023 Neurospine Vol.20 No.3
Objective: Although endoscopic drill has the advantages in manipulation and hemostasis, whose low efficiency and blurred vision reduce the efficacy of lumbar endoscopic unilateral laminotomy with bilateral decompression (LE-ULBD). The present study was designed to evaluate the safety and efficacy of full-visualized trephine/osteotome in the LE-ULBD surgery for severe lumbar stenosis. Methods: Fifty-seven severe lumbar stenosis patients who underwent LE-ULBD between January 2020 to January 2023 were enrolled, who were divided into drill and visualized trephine groups. The medical records including demographics, operative duration, intraoperative electrophysiological findings, postoperative hospital stay or hospital stay, postoperative outcomes and complications were retrospectively reviewed and analyzed. Results: A total of 57 patients included 15 in drill and 42 in trephine group were enrolled in the study. There was significant difference in the pre- and postoperative visual analogue scale and Oswestry Disability Index scores in both groups (p < 0.05). The mean operative duration in the trephine group (101.05 ± 12.18 minutes) was shorter than that in the drill group (134.67 ± 9.68 minutes) (p < 0.05). There was no statistical difference between the 2 groups in electrophysiological monitoring, posthospital stays, postoperative outcomes and complications. Abnormal free-electromyography (EMG) were recorded in 2 (13.3%) and 5 patients (11.9%) in the drill and trephine group. Intraoperative somatosensory evoked potential changes occurred in 3 (20%) and 3 patients (7.1%) in the drill and trephine group and all patients recovered immediately when surgery ended. No serious complications and recurrence occurred in all the patients. Conclusion: Full-visualized trephine/osteotome has been approved to be convenient, safe and efficient in our study, which combined with translaminar inside-out technique and EMG monitoring especially free-EMG may offer a new choice in LE-ULBD surgery for lumbar stenosis patients.
Adsorption and separation of lignin-based aromatic aldehydes using macroporous resins
Zhen Wu,Lei Hu,Ning Xu,Benlin Dai,Jiaxing Xu 한국화학공학회 2015 Korean Journal of Chemical Engineering Vol.32 No.7
Lignin-based aromatic aldehydes (p-hydroxybenzaldehyde, vanillaldehyde and syringaldehyde) have wide applications in flavoring. However, their separation using chromatographic methods has not been explored. We studied the adsorption and desorption behaviors of aromatic aldehydes on macroporous resins and four macroporous resins X-5, CAD-40, AB-8 and D101 were screened for separation of aromatic aldehydes. The results demonstrated that X-5 showed the highest adsorption and desorption capacities. The adsorption capacities for p-hydroxybenzaldehyde, vanillaldehyde and syringaldehyde on X-5 were 33.5mg/g, 46.6mg/g and 47.0mg/g at 20 oC, respectively, higher than that of CAD-40, AB-8 and D101. Adsorption isotherms of aromatic aldehydes on X-5 were confirmed to fit to Freundlich equation which was calculated by lnQe=0.6933lnCe+6.788, lnQe=0.7031lnCe+7.7358 and lnQe=0.7107lnCe+ 8.2412 for p-hydroxybenzaldehyde, vanillaldehyde and syringaldehyde, respectively. The results of dynamic adsorption and desorption experiments demonstrated that 50% (v/v) ethanol solution was an effective elution solvent for aromatic aldehydes. The maximum concentration of the three kinds of aromatic aldehydes in eluent reached 3.74 g/L, 5.44 g/L and 7.03 g/L, which indicated that the elution process was also an effective enrichment process for sorbate.
Determination of Urban Surface Aerodynamic Characteristics Using Marquardt Method
Zhang, Ning,Jiang, Weimei,Gao, Zhiqiu,Hu, Fei,Peng, Zhen Techno-Press 2009 Wind and Structures, An International Journal (WAS Vol.12 No.3
Marquardt method is used to estimate the aerodynamic parameters in urban area of Beijing City, China, including displacement length (d), roughness length ($z_0$) and friction velocity (u*) and drag coefficient. The surface drag coefficient defined as the ratio between friction velocity and mean wind speed is 0.125 in our research, which is close to typical urban area value. The averaged d and $z_0$ are 1.2 m and 7.6 m. d and $z_0$ change with direction because of the surface heterogeneity over urban surface and reach their maximum values at S-SW sector, this tendency agrees with the surface rough element distribution around the observation tower.
Adaptive Algorithm in Image Reconstruction Based on Information Geometry
( Meng Wang ),( Zhen Hu Ning ),( Jing Yu ),( Chuang Bai Xiao ) 한국인터넷정보학회 2021 KSII Transactions on Internet and Information Syst Vol.15 No.2
Compressed sensing in image reconstruction has attracted attention and many studies are proposed. As we know, adding prior knowledge about the distribution of the support on the original signal to CS can improve the quality of reconstruction. However, it is still difficult for a recovery framework adjusts its strategy for exploiting the prior knowledge efficiently according to the current estimated signals in serial iterations. With the theory of information geometry, we propose an adaptive strategy based on the current estimated signal in each iteration of the recovery. We also improve the performance of existing algorithms through the adaptive strategy for exploiting the prior knowledge according to the current estimated signal. Simulations are presented to validate the results. In the end, we also show the application of the model in the image.
Study of Recellularized Human Acellular Arterial Matrix Repairs Porcine Biliary Segmental Defects
Wei Liu,Sheng-Ning Zhang,Zong-Qiang Hu,Shi-Ming Feng,Zhen-Hui Li,Shu-Feng Xiao,Hong-Shu Wang,Li Li 한국조직공학과 재생의학회 2019 조직공학과 재생의학 Vol.16 No.6
BACKGROUND: With the popularity of laparoscopic cholecystectomy, common bile duct injury has been reported more frequently. There is no perfect method for repairing porcine biliary segmental defects. METHODS: After the decellularization of human arterial blood vessels, the cells were cultured with GFP? (carry green fluorescent protein) porcine bile duct epithelial cells. The growth and proliferation of porcine bile duct epithelial cells on the human acellular arterial matrix (HAAM) were observed by hematoxylin–eosin (HE) staining, electron microscopy, and immunofluorescence. Then, the recellularized human acellular arterial matrix (RHAAM) was used to repair biliary segmental defects in the pig. The feasibility of it was detected by magnetic resonance cholangiopancreatography, liver function and blood routine changes, HE staining, immunofluorescence, real-time quantitative PCR (RT-qPCR), and western blot. RESULTS: After 4 weeks (w) of co-culture of HAAM and GFP? porcine bile duct epithelial cells, GFP? porcine bile duct epithelial cells grew stably, proliferated, and fused on HAAM. Bile was successfully drained into the duodenum without bile leakage or biliary obstruction. Immunofluorescence detection showed that GFP-positive bile duct cells could still be detected after GFP-containing bile duct cells were implanted into the acellular arterial matrix for 8 w. The implanted bile duct cells can successfully resist bile invasion and protect the acellular arterial matrix until the newborn bile duct is formed. CONCLUSION: The RHAAM can be used to repair biliary segmental defects in pigs, which provides a new idea for the clinical treatment of common bile duct injury.
Zhou, Chao,Teng, Wen-Jing,Yang, Jing,Hu, Zhen-Bo,Wang, Cong-Cong,Qin, Bao-Ning,Lv, Qing-Liang,Liu, Ze-Wang,Sun, Chang-Gang Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.13
Background: Chronic myelocytic leukemia is a disease that threatens both adults and children. Great progress has been achieved in treatment but protein-protein interaction networks underlining chronic myelocytic leukemia are less known. Objective: To develop a protein-protein interaction network for chronic myelocytic leukemia based on gene expression and to predict biological pathways underlying molecular complexes in the network. Materials and Methods: Genes involved in chronic myelocytic leukemia were selected from OMIM database. Literature mining was performed by Agilent Literature Search plugin and a protein-protein interaction network of chronic myelocytic leukemia was established by Cytoscape. The molecular complexes in the network were detected by Clusterviz plugin and pathway enrichment of molecular complexes were performed by DAVID online. Results and Discussion: There are seventy-nine chronic myelocytic leukemia genes in the Mendelian Inheritance In Man Database. The protein-protein interaction network of chronic myelocytic leukemia contained 638 nodes, 1830 edges and perhaps 5 molecular complexes. Among them, complex 1 is involved in pathways that are related to cytokine secretion, cytokine-receptor binding, cytokine receptor signaling, while complex 3 is related to biological behavior of tumors which can provide the bioinformatic foundation for further understanding the mechanisms of chronic myelocytic leukemia.