폐 CCA 방부처리 목재의 친환경적 소각 및 재활용

최용석,김규혁 고려대학교 2009 생명자원연구 Vol.17 No.-

Multiple cardiac metastases from a nonfunctioning pancreatic endocrine tumor

( Yong Hyeok Choi ),( Hye-suk Han ),( Sung-nam Lim ),( Sang Yeub Lee ),( Ji Hae Koo ),( Ok Jun Lee ),( Ki Hyeong Lee ),( Seung Taik Kim ) 대한내과학회 2011 대한내과학회 추계학술대회 Vol.2011 No.-

Multiple cardiac metastases from a nonfunctioning pancreatic endocrine tumor

( Yong Hyeok Choi ),( Hye Suk Han ),( Sung Nam Lim ),( Sang Yeub Lee ),( Ji Hae Koo ),( Ok Jun Lee ),( Ki Hyeong Lee ),( Seung Taik Kim ) 대한내과학회 2011 대한내과학회 추계학술대회 Vol.2011 No.1

Introduction: Pancreatic endocrine tumors (PETs) are uncommon neoplasm and the most common metastatic site is liver. However, intrathoracic metastasis of PET is very rare. The authors report a case of nonfunctioning PET with multiple cardiac metastases. Case report: A 56-year-old man presented with progressively worsening palpable abdominal mass. Computed tomography (CT) scan of abdomen revealed relatively well marginated inhomogeneous low attenuation masses in the head and tail of pancreas. CT scan of chest and transthoracic echocardiography showed multiple, enhancing masses in left pericardium. A needle biopsy was performed on the masses in the tail of pancreas and left ventricular apical pericardium; histologic examination revealed PET by morphology on H&E and by immunohistochemical staining which was positive for synaptophysin, chromogranin, and CD 56. Conclusion: This is the first report of PET with multiple cardiac metastases of previously undescribed metastatic sites. Although it is very rare, PET has the potential to metastasize to heart or pericardium, and for patients with PETs who present with new cardiac symptoms or signs, the clinician should be alert for the possibility of cardiac metastases.

Seasonal distribution of airborne pollen in Ulsan, Korea in 2009-2010

Choi, Seung-Hyeok,Jung, In-Yong,Kim, Dong-Yeop,Kim, Yang-Ho,Lee, Ji-Ho,Oh, In-Bo,Choi, Kee-Ryong The Ecological Society of Korea 2011 Journal of Ecology and Environment Vol.34 No.4

To determine the peak dispersal times of allergenic pollen grains in Ulsan, Korea, we performed continuous airborne pollen counts at three stations (Sts. A, B, and C) in Ulsan from August 2009 to November 2010. Pollen grains were sampled using a Durham sampler. Two peak pollen dispersal seasons were observed per year. The peak seasons generally coincided with the flowering period of anemophilous trees: Taxodiaceae (February), Alnus (March), Cupressaceae (April), Quercus, and Pinus (May), and with the flowering phase of herbs from August to November, e.g., Humulus, Artemisia, Gramineae, and Ambrosia from August through September. The highest concentration of airborne pollen was from Pinus (68%), followed by Quercus (15%), Alnus (6%), and Humulus (2%); whereas very low pollen concentrations were from Taxodiaceae, Cupressaceae, Artemisia, Gramineae, and Ambrosia (${\leq}$ 1% of the annual total airborne pollen concentration). Our findings indicate that Alnus and Humulus pollen are major allergens whereas those of Pinus and Quercus are minor allergens. The concentration of Alnus pollen grains at St. C was over five times that at Sts. A and B. This finding implies that individuals living at or near St. C are exposed to high concentrations of Alnus pollen before and after March, which is the flowering period of the alder tree. From August to September, individuals living at or near St. B are exposed to high concentrations of Humulus pollen. Our study suggests that Alnus pollen may be the major aeroallergen causing pollinosis in the spring at St. C and Humulus pollen may be the major aeroallergen in autumn at St. B.

HBV : There is Good Correlation between HBsAg and HBV DNA Irrespective of Lamivudine Resistance

( Yong Hoon Choi ),( Jeong Han Kim* ),( Hong Seok Choi ),( Yong Hwang ),( Young Baek Kim ),( Jun Jae Kim ),( Hee Won Moon ),( Soon Young Ko ),( Won Hyeok Choe ),( So Young Kwon ) 대한간학회 2013 춘·추계 학술대회 (KASL) Vol.2013 No.1

Background: It is well known that HBsAg level shows good correlation with HBV DNA level in chronic hepatitis B (CHB) patients. However, there is limited data about correlation between HBsAg level and HBV DNA level in lamivudine (LMV) resistant CHB patients. Methods: Treatment naive CHB patients and LMV resistant CHB patients were included for analysis. Pearson`s correlation coeffi cient between pretreatment HBsAg level and HBV DNA level was calculated. In LMV resistant group, baseline HBsAg level and HBV DNA level before rescue therapy were used. Results: Total forty-eight patients in treatment naive group (Group A) and fifty patients in LMV resistant group (Group B) were enrolled. Male patients were 43 (77.1%) in Group A and 28 (56.0%) in Group B. HBeAg positive patients were 23 (47.9%) in Group A and 29 (58.0%) in Group B. Mean HBsAg was 3.3 log10 IU/mL in Group A and 3.7 log10 IU/mL in Group B. Mean HBV DNA was 5.4 log10 IU/mL in Group A and 6.9 log10 IU/mL in Group B. HBsAg level and HBV DNA level showed good correlation in Group A (r=0.0471, P=0.002), and also in Group B (r=0.531, P<0.001). In HBeAg positive patients, these correlations were also good in both Group A (r=0.530, P=0.019) and Group B (r=0.454, P-0.013). In HBeAg negative patients, correlation was good only in Group B (r=0.498, P=0.022) but not in Group A (r=0.393, P=0.087). Conclusions: Correlation between HBsAg level and HBV DNA level is good in both treatment naive CHB patients and LMV resistant CHB patients. We can assume that LMV resistance does not affect HBsAg secretion. Further investigation about correlation of HBsAg and HBV DNA during treatment is warranted.

Differentially expressed genes in two CCA-tolerant fungi exposed to copper or arsenic

( Yong Seok Choi ),( Yong Il Kim ),( Min Ji Kim ),( Jae Jin Kim ),( Gyu Hyeok Kim ) 韓國木材工學會 2010 한국목재공학회 학술발표논문집 Vol.2010 No.-

녹차 가공 농가 실태 조사

이용호(Yong-Ho Lee) · 최재혁(Jae-Hyeok Choi) · 오주성(Ju-Sung Oh) · 손길만(Gil-Man Shon) 한국차학회 2006 한국차학회지 Vol.12 No.2

This study was conducted to find out conditions of green tea processing and the ways to improve managerial condition. In order to carry out this study we looked into 51 farms producing processed green tea(32 farms in 4 myeons, south Gyeongsang province, 2002, and 19 farms in 2 myeons, 2003). The results of survey are summarized as follows: In green tea processing years, the number of farms with less than 10 years was 27 farms (52.9%), and one farm had more than 30 years. Average yield per farm of processed green tea products was 798 kg/year. The invest cost on facilities and equipment ranged from 4,120 thousand won to 38,400 thousand won. Average point in diagnostic evaluation was 59.7 (48.5 to 75.0). It also showed that 26.4% of the farms were unsuitable for green tea planting. Also it indicated that high investment cost in facilities was one of the problems in green tea processing. Therefore small-size processing facilities or cooperative automated processing facilities were suggested. The main problems in marketing were lack of advertising and dealers, and the sudden drop in price. To improve green tea sales, e-com-merce, opening new markets and advertising were suggested. The income rate of farm with the green tea tree-growing area of 0.7ha was 60.3% which was highest rate.

팽대부 선근종의 임상적, 병리학적, 면역조직화학염색의 특징

최용혁 ( Yong Hyeok Choi ),김미진 ( Mi Jin Kim ),한정호 ( Joung Ho Han ),윤순만 ( Soon Man Yoon ),채희복 ( Hee Bok Chae ),윤세진 ( Sei Jin Youn ),강민호 ( Min Ho Kang ),성노현 ( Rohyun Sung ),최재운 ( Jae Woon Choi ),박선미 ( Seon 대한소화기학회 2013 대한소화기학회지 Vol.62 No.6

Background/Aims: Ampullary adenomyoma is a benign lesion whose malignant potential has yet to be confirmed. Despite its benign nature, adenomyoma is frequently misdiagnosed as a carcinoma or adenoma and is overtreated by extensive surgery. This study was performed to analyze the clinical, pathological, and immunohistochemical features of adenomyomas in the ampulla of Vater. Methods: Nine cases of adenomyoma in the ampulla of Vater, diagnosed in Chungbuk National University Hospital between 2008 and 2011, were enrolled in this study. We reviewed the clinical data on the symptoms, laboratory data, and radiologic findings of the abdominal computed tomography and endoscopic retrograde cholangiopancreatography. For pathological analysis, all the slides were reviewed by one pathologist, and immunohistochemical stainings with antibodies against cytokeratin 7 (CK7), cytokeratin 20 (CK20), α-smooth muscle actin (α-SMA), and Ki-67 antigen were performed. Results: All the cases were CK7 positive and CK20 negative. A strong cytoplasmic expression of α-SMA was confirmed in all cases. The Ki-67 index was less than 1% in eight cases and 5% in one case. Four cases underwent endoscopic papillectomy, and one case received surgical ampullectomy during colorectal cancer surgery. Five cases that underwent endoscopic or surgical treatment remained symptom-free for three years. Four cases that were closely observed with repeated endoscopic examinations exhibited no interval changes in the papillary lesions. Conclusions: Endoscopic biopsy and immunohistochemistry can aid in the diagnosis of ampullary adenomyomas. Endoscopic papillectomy or surgical ampullectomy is adequate for the treatment of symptomatic ampullary adenomyomas. (Korean J Gastroenterol 2013;62:352-358)

환상투열 절제술의 임상적 고찰

최용민(Yong Min Choi),노성혁(Seong Hyeok Noh),정희환(Hee Hwan Chung),이종민(Jong Min Lee),김용욱(Yong Yook Kim),이선(Sun Lee),김영진(Young Jin Kim),이지성(Jee Sung Lee),황병철(Byung Chul Whang),박찬용(Chan Yong Park),최유덕(Yu Duk C 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.2

목적: 연구는 환상투열 절제술후 경계부위 침윤이 자궁경부상피내종양 및 자궁경부 미세침윤암의 치료에 미치는 영향과 경계부위 침윤에 영향을 주는 요인들에 대해 알아보고자 하였다. 방법: 1997년 3월 1일부터 1998년 9월 30일까지 가천의과대학 부속길병원에서 환상투열 절제술을 시행받은 160명의 환자를 대상으로 후향적인 분석이 시행되어졌다. 경계부위 침윤에 영향을 주는 요인들에 대하여 분석하였다. 결과: 결과는 다음과 같다. 1. 최종적으로 127명이 자궁경부상피내종양(CIN)으로, 30명이 자궁경부 미세침윤암으로, 3명이 자궁경부 만성염증으로 진단되어졌다. 2. 경계부위 침윤이 없었던 경우는 81%이었고, 침윤이 있었던 경우는 19%이었다. 3. 경계부위 침윤이 없었던 129례중에서 잔류병소가 발견된 경우는 한 례도 없었으며, 경계부위 침윤이 있었던 31례중 9례에서 잔류병소가 발견되었으며, 전체적으로 잔류율은 6.2%이었다. 4. 자궁경부 상피내종양에서 경계부위 침윤이 있었던 19례중 3례에서 잔류병소가 발견되었고 경계부위 침윤이 없었던 경우에는 잔류병소가 발견되지 않아 잔류율은 2.6%이었다. 5. 경계부위 침윤에 영향을 주는 요인들이 위와 같은 방법으로 분석되어져 조직병리소견의 정도, 선침범, 폐경, 질확대경 검사에 대한 적정성 여부가 경계부위 침윤에 유의하게 영향을 주었으나 분만방법과 HPV감염은 유의하게 영향을 주지 못하였다. 결론 : 환상투열 절제술은 자궁경부 상피내종양의 치료에서 경계부위 침윤이 있더라도 낮은 잔류율 때문에 추적관찰이 이루어지면 불필요한 전자궁 적출술을 줄일 수 있는 충분한 방법이며, 미세침윤암의 치료에서 경계부위 침윤이 없고 림프-혈관계 침윤이 없을 때 추적관찰이 이루어지면 효과적인 방법이 될 수 있다. Objective: To evaluate how resection margin involvement after LLETZ affect treatment of CIN and microinvasive cervical cancer, and several factors affecting the resection margin involvement. Method: Retrospective analysis was performed in 160 patients that underwent LLETZ at Gachon Medical College, Gil Medical Center from March, 1997 to September , 1998. The several factors affecting the resection margin involvement were analyzed. Result: The following results were obtained. 1. 127 patients were diagnosized finally with CIN, 30 patients with microinvasive SCC and 3 patients with chronic inflammation. 2. The rate of the negative resection margin involvement was 81% and that of the positive was 19%. 3. No case among 129 cases with the negative resection margin had residual lesion, but 9 cases among 31 cases with the positive resection margin had residual lesion. As a whole, the rate of residual lesion was 6.2%. 4. In CIN, 3 cases of 19 cases with the positive resection margin had residual lesion, but none with the negative resection margin had. 5. The degree of histopathology, glandular involvement, menopause, colposcopic evaluation were correlated with the resection margin involvement but delivery mode and HPV infection not correlated. Conclusion: LLETZ is a enough method to reduce unnecessary hysterectomy in the treatment of CIN, if followed up, in spite of the positive resection margin because of low rate of lesidual lesion, and is a effective method in the treatment of microinvasive cervical cancer when the case with negative resection margin and no lymphovascular invasion was followed up.

S-345 Castleman``s disease in intrapulmonary lymph node presenting as solitary pulmonary nodule

( Seung Hyeok Choi ),( Seung Yong Park ),( Yeong Hun Choe ),( So Ri Kim ),( Yong Chul Lee ),( Heung Bum Lee ),( Seoung Ju Park ) 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1

Castleman's disease is an uncommon lymphoproliferative disorder which can occur wherever lymph nodes are presens. Castleman's disease in the chest develops usually in mediastinal or hilar lymph node. A 53-year-old woman was admitted to our hospital for further evaluation of a pulmonary nodule detected incidentally in health check up.Computer tomography demonstrated that this nodule was 27×25mm, well-defined in the right upper lobe. On MRI of chest MRI, which was performed to further diagnosis, the nodule was located on perihilar area of the right upper lobe and showed high signal intensity in T2 weight imaging and rapid and strong enhancement in dynamic contrast image, suspected to be a sclerosing hemangioma. We performed right upper lobectomy with lymph node dissection and the pathologic examination revealed that the pulmonary nodule was Castleman's disease arising from an intrapulmonary lymph node. We here report a rare case of Castleman's diseas in intrapulmonary lymph node presenting as solitary pulmonary nodule, suggesting that Castleman's disease should be considered in patinet with a nodule in perihiarl area.