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Clinical and Histopathological Analysis of 66 Cases with Cardiac Myxoma
Zheng, Jian-Jie,Geng, Xi-Gang,Wang, Hai-Chen,Yan, Yang,Wang, Hong-Yan Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3
Background and Purpose: Cardiac myxoma is a major primary heart tumor which often causes unexpected symptoms or sudden death. This present study was designed to investigate its clinical pathological features and biological behavior. Methods: A retrospective analysis of the clinical pathologic and immunohistochemical features of 66 cases with cardiac myxoma was conducted. Results: In 66 patients with cardiac myxoma, 61 cases had involvement of the left atrium, one case in both the right ventricular and left atria. The female: male ratio was 2.7:1. Patients had symptoms of blood flow obstruction and systemic alterations with performance of arterial embolization. Tumors were spherical, lobulated or irregular in shape, and soft and brittle. Immunohistochemical markers of vimentin and CD34 in tumor cells were positive. Conclusion: Cardiac myxoma always exists in the left atrium and is more common in women, with diverse clinical manifestations and pathomorphism. Although proliferative activity and the recurrence rate are low, in addition to thorough surgical resection, strengthened review is important for young patients.
Interconnected hollow carbon nanospheres for stable lithium metal anodes
Zheng, Guangyuan,Lee, Seok Woo,Liang, Zheng,Lee, Hyun-Wook,Yan, Kai,Yao, Hongbin,Wang, Haotian,Li, Weiyang,Chu, Steven,Cui, Yi Nature Publishing Group, a division of Macmillan P 2014 Nature nanotechnology Vol.9 No.8
For future applications in portable electronics, electric vehicles and grid storage, batteries with higher energy storage density than existing lithium ion batteries need to be developed. Recent efforts in this direction have focused on high-capacity electrode materials such as lithium metal, silicon and tin as anodes, and sulphur and oxygen as cathodes. Lithium metal would be the optimal choice as an anode material, because it has the highest specific capacity (3,860 mAh g<SUP>–1</SUP>) and the lowest anode potential of all. However, the lithium anode forms dendritic and mossy metal deposits, leading to serious safety concerns and low Coulombic efficiency during charge/discharge cycles. Although advanced characterization techniques have helped shed light on the lithium growth process, effective strategies to improve lithium metal anode cycling remain elusive. Here, we show that coating the lithium metal anode with a monolayer of interconnected amorphous hollow carbon nanospheres helps isolate the lithium metal depositions and facilitates the formation of a stable solid electrolyte interphase. We show that lithium dendrites do not form up to a practical current density of 1 mA cm<SUP>–2</SUP>. The Coulombic efficiency improves to ∼99% for more than 150 cycles. This is significantly better than the bare unmodified samples, which usually show rapid Coulombic efficiency decay in fewer than 100 cycles. Our results indicate that nanoscale interfacial engineering could be a promising strategy to tackle the intrinsic problems of lithium metal anodes.
Balance Control for the First-order Inverted Pendulum Based on the Advantage Actor-critic Algorithm
Yan Zheng,Xutong Li,Long Xu 제어·로봇·시스템학회 2020 International Journal of Control, Automation, and Vol.18 No.12
In this paper, a control algorithm based on Advantage Actor-Critic for the classical inverted pendulum system has been proposed. To enrich the observed states which are used to control, a CNN feature-based state is proposed. The direct control and the indirect control algorithms are introduced to address different control situations, such as the situation which only physical states like angle, velocity, etc. provided or the situation which only the indirect states provided like images, etc. A comparison experiment between the direct control and the indirect control algorithms based on the Advantage Actor-Critic has been evaluated. Besides, the comparison experiment with the Deep Q-Network algorithm has been performed. The experiment results show that the proposed method achieves comparable performance with the PID control algorithm and better than the Deep Q-Network based algorithm.
Aeromicrobium halotolerans sp. nov., isolated from desert soil sample
Yan, Zheng-Fei,Lin, Pei,Chu, Xiao,Kook, MooChang,Li, Chang-Tian,Yi, Tae-Hoo Springer-Verlag 2016 Archives of microbiology Vol.198 No.5
<P>A Gram-positive, aerobic, and non-motile, rod-shaped actinomycete strain, designated YIM Y47(T), was isolated from soils collected from Turpan desert, China, and subjected to a polyphasic taxonomic study. Phylogenetic analysis indicated that strain YIM Y47(T) belonged to the genus Aeromicrobium. YIM Y47(T) shared highest 16S rRNA gene sequence similarities with Aeromicrobium massiliense JC14(T) (96.47 %). Growth occurs at 20-45 A degrees C (optimum at 30 A degrees C), pH 6.0-8.0 (optimum at pH 7.0), and salinities of 0-7.0 % NaCl (optimum at 4.0 %). The strain YIM Y47(T) exhibits chemotaxonomic features with menaquinone-7 (MK-7) as the predominant quinone, C-16:0, C-18:1 omega 9c and 10-methyl C-18:0 (> 10 %) as major fatty acids. The cell-wall peptidoglycan of strain YIM Y47(T) contained ll-diaminopimelic acid as the diagnostic diamino acid. The polar lipids were found to consist of diphosphatidylglycerol, phosphatidylglycerol, phosphatidylinositol, and unknown phospholipids. The G+C content of the genomic DNA of strain YIM Y47(T) was found to be 44.7 mol%. On the basis of phylogenetic analyses and phenotypic data, it is proposed that strain YIM Y47(T) should be classified as representing a novel species of the genus Aeromicrobium, with the name Aeromicrobium halotolerans sp. nov. The type strain is YIM Y47(T) (=KCTC 39113(T)=CGMCC 1.15063(T)=DSM 29939(T)=JCM 30627(T)).</P>
Zheng-Fei Yan,Jian Guo,Feng-Hua Tian,Xin-Xin Mao,Yu Li,Chang-Tian Li 한국생물공학회 2015 Biotechnology and Bioprocess Engineering Vol.20 No.4
Schisandra chinensis has been used as traditional medicine. The structures of isolate active compounds (schisandrin B, deoxyschisandrin, schisandrin C) from S. chinensis were characterized by physical and spectroscopic analyses. Active compounds were tested for their potential to act as anti-melanogenesis or skin-whitening agents by their abilities to inhibit tyrosinase activity in the cell-free mushroom tyrosinase assay and cellular tyrosinase derived from B16 melanoma cells. The tyrosinase inhibitory activity was correlated to the inhibition of melanin productions in α-MSH-stimulated and unstimulated B16 cells. Cellular tyrosinase kinetics were analyzed and showed by Lineweaver- Burk plot. Schisandrin B was minimally cytotoxic (cell viability: 88.99% at 0.75 μM) and the IC50 value for suppression of mushroom tyrosinase activity was estimated as 0.6 μM. Zymography analysis demonstrated schisandrin B’s concentration-dependent effects and the kinetic analysis indicated schisandrin B’s noncompetitive-inhibitory action.