뇌하수체 종양 제거술 시행 후 뒤늦게 발생한 횡문근 융해증과 동반된 중추성 열

장제혁,최규남,김일환,노은지,김윤정,유충헌,고정해,박봉수,김태균,권민정,이순희,박정현 인제대학교 2008 仁濟醫學 Vol.29 No.-

Body temperature is controlled by thermoregulatory center of the hypothalamus. We report a case of 24 years old man with central fever. He was subjected to a partial excision of pituitary tumor compressing optic chiasm four years ago. He has received hormonal therapy for panhypothyroidism after removal of pituitary tumor. And He received gamma knife operation for partially contrast-enhancing masses in suprasellar and both hypothalamic areas that is probably postoperatively remnant or recurrent tumor of pituitary adenoma. One year after gamma knife operation, he presented with a febrile syndrome of unknown origin including rhabdomyolysis. All usual investigations proved negative. We diagnosed him as central fever with rhabdomyolysis. He received medical ICU care with cooling bed, ice pack. And his symptom improved. Postoperative hyperthermia may result following resection of the pituitary tumor. When central fever is suspected taking note of past history, a quick recognition of course of fever can help reduce the using of unnecessary antibiotics and hospital stay.

컴퓨터 비젼시스템을 이용한 평면상에 있는 점위치 결정에 관한 연구

장완식,이규태,김재확 朝鮮大學校 機械技術硏究所 1998 機械技術硏究 Vol.1 No.1

비젼 시스템이 개발되기 시작한 것은 1973년에 PDP-10 컴퓨터를 이용한 물펌프 조립이 시각정보를 이용하여 Stanford 연구진에 의해 수행되었다. 그 이후, 비젼 시스템이나 비젼센서가 활용되는 예로는 용접, 운반, 조립, 측정 검사 등이 있으나, 지능로봇중의 한 분야로 로봇 비젼시스템을 생산현장에 적용하는 경우가 늘고 있다. 비젼을 사용하면 매니퓰레이터가 우주 공간이나 수중등 실제 공간에서 그 위치와 방향이 불확실하게 알려져 있을지라도 작업을 수행할 수 있다. 따라서, 로봇 비젼 시스템은 주로 대상물의 위치가 불규칙하거나 기구학적으로 위치결정을 하기 어려운 작업의 자동화에 적용이 널리 확대될 것으로 예상된다. (1)(2)(6)(7)(8) 로봇에 비젼을 적용할 때 실제 공간은 3차원인 반면에 비젼 정보는 2차원이기 때문에 카메라 좌표계와 매니퓰레이터나 실제 공간 좌표계를 일치시켜 주는 보정은 가장 중요한 요소중의 하나이다. 카메라 교체시나 카메라 위치 수정시에도 필히 보정을 다시 시켜줄 필요가 있다. 만약 보정이 정확하게 되어 있지 않으면 매니퓰레이터의 경우 올바른 제어를 하지 못할 우려가 있고, 또한 부적절한 보정계수 산출로 인한 목표점의 추정이 어긋나게 된다.(3) 이리하여 본 연구는 이러한 문제점을 해결하기 위하여 6개의 시각 매개변수를 이용한 새로운 비젼 시스템 모델을 제시하고, 2차원 평면 점위치 결정 실험을 통하여 제시한 비젼 모델의 적합성을 검증한다. 본 실험에서 사용되는 비젼 시스템은 두 대의 고정된 카메라를 작업공간에 설치하여 이용한다. 본 연구의 제한 조건은 평면상에 존재하는 알려지지 않은 물체의 위치 결정을 위해서는 그 물체 주위에 알려진 몇 개의 좌표값이 존재해야 한다는 것이고, 본 연구에서는 알려지지않은 점으로부터 위치가 알려진 점과의 거리에 대한 상관관계, 위치가 알려진 점의 개수에 대한 상관관계 및 결정된 물체 위치의 정확성을 실험을 통하여 검증하고자 한다. This paper presents the application of computer vision for the purpose of determining the position of the unknown point in the plane. The presented control method is to estimate the six view parameters representing the relationship between the image plane coordinates and the real physical coordinates. The estimation of six parameters is indispensable for transforming the 2-dimensional camera coordinates to the 3-dimensional spatial coordinates. Then, the position of unknown point is estimated based on the estimated parameters depending on the cameras. The suitability of this control scheme is demonstrated experimentally by determining position of the unknown point in the plane.

평생건강교실 프로그램이 노년기 여성들의 건강관련체력과 혈중지질에 미치는 영향

장경태,이규성,안종철,김문희,이미화,오재근 韓國體育大學校 1998 論文集 Vol.21 No.-

The purpose of this study were to investigate the effects of participation of health program on health related physical fitness and blood lipids in olderwomen. The subjects participated in this study were 52 older who were participated physical activity program in Korean National University of Physical Education. The analysis of this study utilized one way ANOVA design. The results of the study were as follows : 1. According to taking the treatment periods(0, 6, 12), body composition, hand grip, sit and reach, sit up, and 3200m walking were no significant difference. 3. According to taking the treatment periods(0, 6, 12), TC, TG, LDL-C, HDL-C and VLDL-C were a significant difference in p<.001 levels.

퍼지신경회로망을 이용한 로봇 매니퓰레이터의 힘 제어

양태규,장기훈 목원대학교 자연과학연구소 2000 自然科學 硏究論文集 Vol.9 No.1

본 논문에서는 퍼지신경회로망 제어기를 이용하여 미지의 환경에서 로봇 매니퓰레이터의 접촉 힘 제어기를 제안하였다. 환경에 접촉 또는 힘을 가하고 있는 로봇 매니퓰레이터는 인간의 생각하는 방식과 유사한 제어를 위해 퍼지 제어기를 사용하고, 그 때 원하는 접촉 힘을 얻기 위하여 소속함수와 규칙들을 적용하고 신경회로망으로 모델링 하였다. 이는 환경과 접촉하고 있는 로봇 매니퓰레이터의 불확실성과 비선형성을 극복하기 위한 것으로써, 제어기의 입력 신호로 로봇 매니퓰레이터의 위치와 힘 오차를 사용하였다. 시뮬레이션을 통하여 제안된 퍼지신경회로망 제어기의 타당성을 입증하였다.

급성백혈병의 화학요법에서 조혈간세포 보충요법

이규보,배선근,손상균,이재태,이건수,이경혜,서장수 경북대학교 병원 1997 경북대학교병원의학연구소논문집 Vol.1 No.1

1. 목적 급성백혈병의 화학요법에 있어서 관해유도 요법시에 보다 더 강력한 항암화학요법을 시행하고 골수억제의 회복을 위하여 말초혈액에서 채취한 조혈모세포의 투여로 그 효과를 증대시키고자 시도하였다. 2. 방법 관해유도 화학요법후에 골수억제시기로부터 회복단계로서 백혈구감소증이 호전도면서 단핵세포가 증가될 때에 말초혈액에서 조혈간세포(stem cell)로 인정되고 있는 CD34+세포의 함유량이 1% 이상되는 시기를 찾아내고 그 때부터 평균 4차례의 단핵구를 분리채집을 하여 -74。C에 냉동보관하였다가 제2차 화학요법후에 해동시켜서 정맥주입하였다. 3. 결과 대상 급성백혈병환자는 6명에 23회의 조혈간세포를 함유한 단핵구 채집을 시행하였고 유효한 단핵구의 채집은 4례에서 가능하였고 2례에서는 유효한 채집이 못되었다. 채집효율은 39.0-74.5%로서 평균 49.8%였다. 채집 후에 혈액학적 변화는 혈색소의 약간 감소 (평균 1.34g/dl)와 혈소판의 감소 (평균20.25%)를 나타내었다. 해동 단핵구를 투여할시에 일과성인 불쾌감, 기침, 흉부압박감, 호흡곤란 등이 있었다. 4. 결론 자가골수이식에서 자기말초혈액조혈간세포이식으로 관심이 이행되는 현시점에 자가조혈간세포를 채집하여 수혈하는 기술이 확립되는 기초를 이루었다고 본다. 이번 대상들은 재발된 금성백혈병들에 시행하였으나, 향후에는 초발시에 제일차 관해유도 화학요법 과정에 시도해야할 것으로 생각한다. Object: Peripheral blood stem cells(PBSC) were collected after remission induction chemotherapy and reinfused after intensified chemotherapy in order to increase the chemotherapeutic efficacy. Method: Collection of mononuclear cells (MNC) was started when CD34+ cells above 1% and WBC above 1,000/ul with mononuclear cell percentage above 30%, the collection procedures were done 2-6 time in each patient of total 6 cases. The collected MNCs were stored in - 750C and reinfused after thawing in the water bath at 370C Results: Twenty three collection procedures from the 6 cases of acute leukemia had made effective MNC collection in 4 cases and mean collection efficiency was 49.8%(from 39.0% to 74.5%). Hematological changes after the procedure were mean reduction of hemoglobin 1.34g/dl and mean 20.25% of decreased platelet count. There were noticed transient symptoms of discomfort, coughing, chest tightness and dyspnea in association with the infusion of stored cells. Conclusion: The basic process for the peripheral blood stem cell transplantation (PBSCT) was accomplished with this supportive care for the consolidation chemotherapy of acute leukemia. Effective PBSCT would be warrented with more qualified process and high does chemotherapy. (Korean J Blood Transfus 6(2) : 41~47,1995)

患者에서 分離된 포도구균이 分泌하는 β-lactamase의 性狀에 關한 硏究

朴粧緖,朴鼎圭,崔大卿 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.1

This study was carried out for the purpose of investigating the β-lactamase producing rates using acidimetric assay and disc method. Also, the author evaluated the drug resistance of ,β-lactamase producing staphylocci isolated from 34 patients in Chungnam National University Hospital and 25 medical students in Chungnam National University by antibiotic susceptibility test. The author sconducted the survey from January to June 1985. The results obtained were as follows: 1. Out of the 34 specimens from patients, Staphylococcus aureus isolated from pus and throat were 58.8% and 17.6%, respectively. 2. The β-lactamase producing rates of staphylococci isolated from patients and control groups using acidimetric assay after 1 year were 88. 2% and 84. 0%, respectively. 3. In the disc method and acidimetric assay, the (β-lactamase producing rates of staphylococci isolated from patients and control groups were 91.2%, 88.2% and 88.0%, 84. 0%, respectively. 4. The rates of resistance for penicillin among p-lactamase producing strains of staphylococci isolated from patients and control groups were 91.2% and 60.0%, respectively. 5. Out of the β-lactamase producing staphylococci isolated from patients and control groups, 88. 2% and 56. 0% were resistant to penicillin but sensitive to cephalothin.

일부 도시지역 노인들의 우울과 일상생활능력에 관련된 요인

박원규,이태용,정용준,오장균,이동배,조영채 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

This study was performed to provide the basic data and related factors available for the assessment of the degree of ADL and depression among older persons, manifesting their physical and psychological status. The subjects included the old people aged more than 65 years old who reside in urban areas. The interviews were delivered to 693 individuals in Taejon metropolitan city during the two-month period from June to July, 2000, and Zung Self-Rating Depression Scale and IADL developed by Older American Resources and Services of Duke medical college, were employed for the assessment of depression and IADL, respectively. The collected data were statistically processed by SPSSWIN(ver 10.0) and led to the following results. The degree of depression among 635 subjects showed that 26.6% had mild depression, 8.2% moderate and 0.6% severe while 64.6% were normal. In terms of IADL, 6.9% had impossible IADL when not aided by others, 37.0% needed some help, 56.0% possible IADL, and the higher depression scores, the significantly higher IADL scores. Based on general characteristics, depression scores were significantly higher in the female group, the older, the lower educated, the ones without cohabitants, without a spouse, without making expenses of living on their own, and IADL scores were lower, meaning the lower capability for performing daily activities, in the male group, the older, the higher educated, the group without a spouse, without making expenses of living on their own. Based on daily activities and psychological characteristics, depression scores were higher in the group who don't go out, who don't have recreational or friendly gatherings, who aren't satisfied with the lives of the past or present, who have a sense of isolation, and who don't have the will to live, and IADL scores were lower in the group who don't go out, who don't have recreational or friendly gatherings, who aren't satisfied with the lives of the past or present, who have a sense of isolation. and who don't have the will to live. Multiple regression analysis revealed that the explanatory variable having effects on depression symptoms included, with the explanatory power of 57.5%, the confidence in life, the degree of education, the subjective index of health, the sense of isolation, the exercise, the degree of IADL, the gender, the level of satisfaction with life, whether they eat breakfast or not, the concern about life, the smoking, the going out, the presence of spouse or not. The explanatory variables having effects, with the explanatory power of 28.9%, on IADL scores included the degree of depression symptoms, the age, the presence of friends or not, the frequency of outgoing, the level of education, the degree of obesity, the confidence in life, the level of satisfaction with life, the drinking or not. The study results showed that the higher depression scores had a tendency to be associated with the decreased capabilities of performing daily activities, and that the factors related to depression and/or IADL, included the confidence in life, the level of education, and the level of satisfaction with life. However, the more detailed and decisive results on the factors related to depression and IADL of the older persons are considered to require continuing efforts and comparisons among a variety of the older population.

異功散의 免疫增强效果에 관한 實驗的 硏究

안규석,이경태,장성구,정지창,노영수 世明대학교 한의학연구소 1999 韓醫學硏究所 論文集 Vol.2 No.-

This experimental study was carried out to evaluate the immunomodulatory effects of Ekong-san. To evaluate the immunomodulatory effects of Ekong-san, delayed type hypersensitivity, hemagglutinin and hemolysin titers for hymoral immune response, rosette forming cells for cell-mediated immune response, natural killer cell activity, proliferation of lymphocyte, productivity of Interleukin-2, and carbon clearance were measured with methotrexate treated mice. The results were summarized as follows; 1.The influence of the treatment on hemagglutinin and hemolysin titers, rosette forming cells, the proliferation of lymphocyte, and productivity of Interleukin-2 was dose-dependent and the results showed a significant difference when compared to control group. This implies that the humoral immune response was activated. 2.The natural killer cell activity was significantly increased in both sample groups as compared to the control group when the effector cell:target cell ratios were 100:1 and 0:1. However when the ratio was 10:1, there was no significant difference with the control group. 3.Carbon clearance, the proliferration effect of phagocytes was significantly increased sample group as compared to the control group. According to the results, Ekong-san has the immuno-activity. We could suggest that Ekong-san is able to be applied to the anti-cancer treatment and prevention.

석탄폐석을 이용한 폴리머 콘크리트의 물리 역학적 특성

연규석,최동순,장태연,주명기 강원대학교 석재복합신소재제품연구센터 석재연 논문집 Vol.1 No.-

최근의 급속한 경제성장과 건설물량의 증가로 인한 수요가 급격히 증대되고 있으나, 양질의 콘크리트용 골재 부족현상을 초래하고 있어 골재의 양적인 문제와 함께 질적인 문제의 해결이 건설재료 분야의 중요한 당면과제로 제기되고 있다. 따라서 본 연구에서는 강원도 탄광지역에 다량으로 산재되어 있는 석탄폐석을 콘크리트용 골재로서 활용하여 고강도이며 내구성이 우수한 폴리머 콘크리트를 제조하고 이에 대한 물리·역학적 특성을 실험적으로 구명하여 공장제품 재료로서의 이용을 위한 기초자료로서 제공코저 한다. Lately, rapid expansion of construction industry and following increment of demand for concrete in the construction created shortage of aggregates in the nation. Supplement of god quality aggregate is an immediate issue for the construction industry to solve. Therefore, this study evaluated a possibility of using coal mine waste collected from Kwangwon-do region as a source of aggregate in manufacturing polymer concretes which have high strength and high durability. First, aggregates were obtained by crushing coal mine waste and polymer concrete was manufactured using these aggregate. Mechanical property test results for the polymer concrete showed that the coal mine waste aggregates were acceptable to use as a replacement of the aggregate in polymer concrete manufacture.

정신과 입원환자의 공격행동 특성

전태연,권용실,도규영,장계호 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.3

저자들은 1994년 1월 1일부터 1995년 6월 31일까지 가톨릭대학교 의과대학 의정부성모병원 정신과에 입원했던 환자들 중세서 공격행동을 보인 환자(공격군) 72명과 공격행동이 없었던 환자(비공격군) 215명의 임상적 특성에 관한 조사를 하여 다음과 같은 결과를 얻었다. 1) 공격행동을 보인 환자는 72명으로 전체 조사 환자의 25.1%이었다. 2) 성별, 연령, 종교, 결혼 상태와 정신과 질환의 가족력 등에 따른 공격행동의 발생비율의 차이는 유의하지 않았다. 3) 교육 정도와 직업에 따른 공격군의 비육에 유의한 차이가 있었다(p<.05). 4) 진단별로는 공격군에서 조증, 기질성 정신장애, 정신분열증의 빈도가 높았으나 진단에 따른 의미 있는 차이는 없었다. 5) 공격행동의 기왕력은 공격군에서 더 많았고 비공격군과 비교시 의미 있는 차이를 보였으며(p<.001), 입원 형태는 공격군에서 타의 입원의 빈도가 유의하게 높았다(p<.005). 7) 입원시 정신병리는 초조-흥분과 적대감-의심에서 공격군의 빈도가 높았으며 정신병리에 따른 의미 있는 차이를 보였다(p<.001). 8) 총 재원 일수는 공격군에서 평균 59.3일이었고 비공격군이 평균 38.4일로 유의한 차이를 보였다(p<.001). 9) 공격행동의 유형은 말로한 경우가 가장 많았고 물건을 대상으로한 행동, 타인을 대상으로 하는 행동의 순으로 나타났다. 10) 공격행동 직전 행동 특징은 활동증가, 시끄러움, 욕설, 분노, 적대적이었던 경우가 가장 많았다. 11) 공격행동은 정오에서 오후 6시 사이, 휴식시간에 가장 많이 나타났다. 12) 입원 후 1주일 이내에 공격행동의 62.3%가 나타났다. 13) 총공격 점수에 의미 있게 영향을 주었던 변인들로는 종교(p<.05), 교육 정도(p<.05), 직업(p<.05), 입원형태(p<.005), 진단(p<.001), 입원시 정신 병리(p<.001), 공격행동의 기왕력(p<.001) 등으로 나타났다. To evaluate the characteristics of violent behavior of psychiatric inpatients the authors reviewed clinical records of psychiatric patients who had admitted at UiJong Bu St. Mary's Hospital from January 1994 to June 1995. We divided the 287 subjects into violent and nonviolent group according to the presence of violent behaviors in psychiatric ward. We assessed demographic variables, clinical characteristics and violent behaviors using Overt Aggression Scale and compared these variables of violent group with nonviolent group. The results were as follows : 1) The number of violent patients was 72(25.1% of the total). 2) In terms of demographic variables, the differences between two groups in education and occupation were significant(p<.05). 3) In psychiatric diagnoses, violent group were more likely to have mania, schizophrenia and organic mental disorder in sequence but there were no differences between violent and nonviolent group. 4) The history of violent behavior was greater in violent group(p<.001) and the mode of admission was significantly different between two groups(p<.005). 5) In cluster of psychopathology on admission, more frequently found clusters of psychopathology in violent group were agitation-excitement and hostile- suspiciousness and there were significant differences between two groups(p<.001). 6) The length of stay in violent group(59.3 days)was significantly longer than nonviolent group(38.4 days)(p<.001). 7) The types of violent behavior were verbal aggression, physical aggression against objects and physical aggression against other people in frequency sequence. 8) The most frequent type of behavioral clue before violent behavior was hyperactive, loud, verbally abusive, angry, hostile(68.1%). 9) Most of violent behaviors were presented between midday and 6 pm. in resting time. 10) 62.3% of total violent behaviors were occurred within first week following admission. 11) The variables which showed significant effects on total aggression score were religion, educational status, occupation, mode of admission, psychiatric diagnosis, psychopathology on admission and history of violent behavior before admission. In summary, these results showed similar trends compared to previous studies on characteristics of psychiatric inpatients. And we found that more important predictors of violent behavior in practice were likely to be history of violent behavior, psychopathology on admission and behavioral cue before violent behavior.