열간 단조용 금형강 SKD61의 열처리에 따르는 기계적 성질의 변화

이찬규,최영선,윤재홍,조대현,신희권 國立 昌原大學校 産業技術硏究所 1997 産技硏論文集 Vol.11 No.-

The best heat treatment conditions for improving mechanical properties was invastigated about effecting of solution treatment and tempering temperature in various condition of SKD61. The mechanical property of SKD61 has been studied by tensile, hardness and sharphy test, and observation microstructure.

부모 효율성 훈련의 효과 고찰

李羲伸 서강정보대학 1995 論文集 Vol.14 No.-

The purpose of this study was to investigate the effect of P.E.T. The effect of P.E.T. have been evaluated in separate research studies, copies of which are on file in the research library of Effectiveness Training Incorporated. The quality of these studies varies considerably with respect to the kinds of instruments used,the size of samples employed,the degree to which other variables are controlled,and the statistical techniques chosen by the experimenters. Nevertheless, all of them found changes that were statistically significant. The specific findings from these studies are briefly stated in the following section. Changes in the parents after P.E.T. 1. Parents showed increased confidence in themselves in the role of parent. 2. Parents showed increased acceptance of their children. 3. Parents showed increased trust in their children. 4. Parents showed increased understanding of their children's behavior. 5. Parents showed on increase in democratic attitudes and a decrease in authoritarian attitudes practices. 6. Parents showed improvement in overall parental attitudes and child rearing behaviors. 7. Parents showed improvement in their self-esteem. 8. Parents showed a reduction in the number of problems with their children. 9. Parents showed a reduction in anxiety. 10. Parents showed an increase in the use of progressive educational practices. 11. Parents improved their scores on tests of empathy, understanding, positive regard, congruence, and acceptance. 12. Mothers and fathers made equal gains in overall positive parental attitudes. 13. Parents showed more willingness to accept children's right to hold beliefs different from parent's. 14. Parents and their children showed no significant decrease in "interpersonal distance". Changes in the children of P.E.T. Parents 1. Children who participated with their parents in P.E.T. showed a progressive increase in the level of moral reasoning on Kohlberg's Scale. 2. Children of P.E.T. parents designated as underachievers gained an average of one full grade point in school. 3. Children of P.E.T. parents perceived them as having increased their acceptance of them as persons. 4. Children of P.E.T. parents showed a decrease in inappropriate and disruptive behaviors. 5. Children of P.E.T. parents showed increase in self-esteem.

사춘기전 치주염 치료시 공제영상 측정법 이용에 대한 증례보고

최신규,이광희 大韓小兒齒科學會 1993 大韓小兒齒科學會誌 Vol.20 No.2

Subtraction technique has increased detectability of small osseous changes compared with conventional radiograph. We used subtraction technique in analysis and evaluation of the bone density change before and after the treatment of prepubertal periodontitis in an eleven-year-old female patient. The patient was examined clinically, hematologically and radiologically. Clinical examination showed periodontal abscess in maxillary right second premolar and first molar area and gingival swelling in maxillary left premolar area. The result of hematological analysis was within normal limit. Radiological examination showed vertical bone resorption at maxillary right first premolar and first molar and also periapical lesion at maxillary right premolar. The patient was treated by subgingival curettage, endodontic treatment and reconstructive osseous surgery. Hydroxyapatite was filled in mesial and distal area of maxillary right first premolar and mesial area of maxillary first molar. In radiographic view at 6 months after operation, normal bony trabecular pattern was observed in the defect area which was embedded by HA. Apical lesion disappeared and lamina dura has a normal pattern. Daily mechanical removal of plaque by patient was emphasized for the success of treatment. This study revealed that the subtraction technique increased the accuracy of radiograph reading in the treatment of periodontitis.

하악지시상분할절단술에서 자가수혈의 이용시 혈액학적변화에 관한 연구

김신헌,윤형기,박진혁,김우형,이희철,Park, Jin-Bae 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.4

Objective : s we has known risk of acquired immunodeficiency disease due to trans-fusion, we recognize the importance of autologous blood transfusion. Since 1990, the use of autologous blood transfusion was increased in Korea. The use of autologous blood transfusion in orthognathic surgery is common. The purpose of this research is to determine, in patients undergoing sagittal split ramus osteotomy, clinical predictive cri??eria for preoperative autologous blood donation and to propose guidelines to increase the efficiency of it. Methods and Material : This article reviewed one hundred two patient who had received bilateral sagittal split ramus osteotomy with autologous blood donation in oral and maxillofacial surgery, Paik hospital, Pusan, from January 1995 to December 1999. Hemoglobin & hematocrit change was evaluated pre- and postoperatively, and erythropoiesis, relationship between procedure time and blood loss was evaluated. Results : 1. Mean age of male patient was 23.1 years and that of female patient 22.5 years. Mean body weight was 73.7㎏ in male and 49.4㎏ in female. 2. Preoperative autologous blood donation unit was mean 1.9 unit(1unit=320㎖), and transfused unit was mean 1.3 unit. 3. Three of 102 patients had positive reaction for hapatitis B virus, but no complication were occurred. 4. The interval from initial donation of autologous blood to surgery was 19 days, and from last donation to surgery was 11 days. 5. Mean hemoglobin levels in predonation period were 15.1 g/㎗ in male and 12.7g/㎗ in female. Hemoglobin and hamatocrit levels decreased by 1.0g/㎗ and 3.2% in male and 1.1g/㎗ and 3.3% in female, respectively, after collection of 1 unit of autologous blood, and decreased by 1.8 g/㎗ and 6.4% in male and 1.9 g/㎗ and 6.9% in female after collection of 2 units. 6. Preoperative erythropoiesis from first donation to surgery showed no statistically significant difference between male and female patients. 7. Estimated blood volume(EBV) ranged from 4,100㎖ to 5,800㎖ in male and from 2,600㎖ to 3,600㎖ in female. Mean estimated blood loss(EBL) was 640㎖, and up to 32% of EBV. 8. All 25 patients with more than 20% loss of EBV were trnasfused intraoperatively, and 18 of 24 patient with 16-20% loss, 16 of 30 patient with l1~15% loss, 7 of 20 patient with less than 10% loss were transfused. Transfusion requirement was increased parallel to EBV. Conclusion : It seems that the proper unit of autologous blood donation is 1.3 unit, and autologous blood transfusion is a safe method in elective surgery that predicted large blood loss. In the future, if transfused blood was controlled based on hypotensive anesthesia, preoperative hemoglobin and hemotocrit level, the proper level of autologous blood transfusion will be accomplished.

진행성 위암환자에서 Capecitabine/Cisplatin 치료군과 Fluorouracil/Cisplatin 치료군 간의 삶의 질 비교

유희원,신은정,이광자,한현주,손인자 韓國病院藥師會 2004 병원약사회지 Vol.21 No.1

The improvement of medical treatment and anticancer drug has led a complete recovery and prolonged survival time of cancer patients. And recent study of cancer has included evaluation of quality of life. This study was performed to evaluate quality of life between Capecitabine/Cisplatin arm and Fluorouracil/Cisplatin arm. This study was performed in the Seoul National University Hospital from August to October 2003. A total of 8 AGC patients on adjuvant chemotherapy successfully completed this study. Method of study is questionnairing by EORTC QLQ-C30, cancer specific questionnaire. The questionnaire consists of Functional, Symptom, Global health quality of life scale. Patients eligible for this study had histologically confirmed stage III or IV AGC. Patients were to be between 18 and 60 years old, and have performance status of 1. Patients were ineligible if they had a history of 6 months prior or concomitant chemotherapy, radiotherapy. Statistically significant differences favoring the Fluorouracil/Cisplatin arm was noted in the physical scale. In addition, patients in the Fluorouracil/Cisplatin arm reported an improvement in physical functioning after one cycle chemotherapy.

동결 건조기의 최적 운전 기법

裵信徹,李近熙 단국대학교 1993 論文集 Vol.27 No.-

The problem of operating a freeze dryer to obtain a fixed final moisture content in minimum time is formulated as an optimal control problem. The energy radated from the heat plate, and total pressure in drying chamber are considered as control variables. Constraints are placed on the system state variables by the scorch point of the dried product and the melting point of the frozen interface. The optimum control policy at the beginning of the run, when neither of the two temperature constraints is active, has been establishen through a theoritical analysis under pseudo-steady state assumptions. For certain cases the nature of the overall optimum control policy has been found. The numerical solution of the steady and nonsteady state problem indicates that if a control policy is optimum for the steady state problem, then this control policy is also optimum for the nonsteady state problem.

합성펩타이드를 이용한 영양배엽세포-특이 가토 다클론 항혈청의 제작

이희섭,오재민,김정중,문형배,김원신,이황희 원광대학교 생명공학연구소 1995 생명공학연구소보 Vol.3 No.1

Within the last few years, a different approach to generating protein-reactive antibodies has been developed that has several advantages over conventional immunization. This involves synthesizing short peptide sequences, coupling them to immunogenic carrier molecules, and immunizing animals with the conjugates. 3βHSD(3β-hydroxy-5-ene steroid dehydrogenase; EC 1.1.1.145) is the enzyme of the plasma membrane of human trophoblast and it's cDNA sequence was identified by Nickon et al(Molecular cloning and expression of human trophoblast antigen FDO161G and its identification as 3β-hydroxy-5-ene steroid dehydrogenase. J Reprod Fert 1991;149;156). For the production of trophoblast-specific antibody, we synthesized three oligopeptides that are epitope sites chosen from cDNA sequence of 3βHSD. Oligopetides were coupled with KLH(keyhole limpet hemocyanin) under 25% glutaraldehyde. The trophoblast-specific rabbit polyclonal antisera was produced by conventional methods. This antisera reacts with a 43kDa protein in human placental lysate by Western blotting analysis and The syncytiotrophoblasts and cytotrophoblasts from villi are stained positively with this antisera by immunohistochemistry. Villous trophoblasts were cultured in methionine-free media for 1 hour and [^(35)S]-Methionine for 24 hours. Media and cell lysate were immunoprecipitated with this antisera and 12% SDS-PAGE was performed. In fluorography, bend was not noted in media and 43kDa band was noted in medis and 43kDa band was noted in lysate. It was concluded that anti-3βHSD antibody produced by synthetic peptide was specific to trophoblasts and 3βHSD was membrane-bound protein of trophoblasts.

生長調節物質의 處理가 고추의 着果 및 果實特性에 미치는 影響

金永信,呂承淑,李禧珠,李政明 경희대학교 부설 식량자원개발연구소 1991 硏究論文集 Vol.12 No.-

A series of experiments were conducted to investigate the effect of some growth regulator treatment on the fruit set and fruit growth in a male sterile inbred line of hot pepper(Capsicum annuum ) which normally bears bean-sized tiny fruits only. Major results can be summarized as follows. 1. In the first experiment, which was consisted of Tomtlane treatments alone or in combination with gibberellic acid, fruit growth was not significantly influenced by any of the treatments. Only the hand-pollinated flowers with viable pollens from other fertile plants gave rise to significantly larger fruits suggesting that competition for nutrients within a plant may reduce the effectiveness of the chemicals treated. 2. 2, 4-D treatment, dipping the flowers in l00ppm solution, was found to be the most effective in inducing parthenocarpic fruit enlargement as compared to other chemicals in the second experiment. 3. In the 3rd experiment, which included all the treatments tested in the first and second experiments, 2,4-D treatment was found to be the most effective followed closely by Tomatotone (p-CPA) treatment. 4. Addition of gibberellic acid to Tomatotone appeared to increase the effectiviness of Tomatotone treatment. Addition of gibberellic acid to NAA or Tomatlane failed to show any significant additive effect. 5. Highly significant postitive correlation was found between the fruit fresh weight and the fresh weight of the placentae tissue thus suggesting the important role of placentae tissue in enlargement of fertilized fruits.

GC 및 GC/MS에 의한 생체시료중 Methidation의 분석법에 관한 연구

이종숙,이재신,최동기,양희진,한백희,구기서 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

정맥내 통증자가조절법을 이용한 Nalbuphine-Ketorolac과 Butorphanol-Ketorolac의 술후 진통효과 비교

윤석화,이원형,손수창,신용섭,김윤희,양신영 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

This study aimed to compare analgegic efficacy, satisfaction score and side effect of nalbuphine-ketorolac and butorphanol-ketorolac by using intravenous patient controlled analgesia(IV-PCA) for postoperative anlgesia following a gastrectomy for stomach cancer. Ninety patients who had undergone gastrectomy for stomach cancer under general anesthesia were randomly divided into two groups. Each group recieived nalbuphine 50mg with ketorolac 150mg(Group 1, n=45) and butorphanol 5mg with ketorolac 150mg(Group 2, n=45) by using IV-PCA during postoperative 48hrs. Assessments for pain with numerical rating scale(NRS), and side effects were evaluated at 2hr, 6hr, 12hr, 24hr, 36hr and 48hr after the operation. There were no significant difference in NRS for pain during rest, but Group 2 requested significantly greater amount of supplementary diclofenac during first 24 hours. Side effects were higher Group 1 in pruritus, nausea and vomiting and Group 2 in sedation, nausea and vomiting. This study suggests that adding ketorolac with intravenous nalbuphine or butrophanol in using an intravenous PCA can decrease analgesics requirement and improve analgesic property without the major morbidity like respiratory depression, but needs for the careful observation and treatment on the side effects like nausea. vomiting, pruritis and sedation...