‘숙명역사관’뮤지엄 아이덴티티 개선을 위한 마케팅, 디자인 전략 수립 -특별 기획전, 홍보, 기프트 샵을 중심으로-

박민지,박한빛,서예원,이진민,장미정,이성애 숙명여자대학교 산업디자인연구소 2017 숙명디자인학 연구 Vol.24 No.-

본 연구는 디자인과 마케팅이 이분법적으로 나누어질 수 없음을 인식하고, 디자인과 마케팅을 융합하여 스페이스 디자인 마케팅을 통한 뮤지엄아이덴티티를 구축하는 일련의 프로세스를 제안하는데 목적이 있다. 본 연구는 2017년 3월~6월 총 15주간 숙명여자대학교 환경디자인과 ‘브랜드·스페이스·마케팅’수업에 서 진행된 결과물로서 작업물을 정리하였다. 본 연구의 범위는 4개(物, 事, 人, 場)의 주제 중, 장소(場)를 중심으로 ‘숙명역사관’의 그래픽, 제품, 공간을 개발하는 브랜드 매뉴얼과 연관하여 한정한다. 이에 본 연구는 ‘숙명역사관’이 가지고 있는 역사적 컨텐츠와 가치를 통해 현재 상황과 문제점을 분석하였다. 그 결과 ‘숙명역사관’의 다양한 마케팅 전략을 제시하고 이에 따른 디자인 전략과 해결 방안을 통해 디자인과 마케팅의 융합을 꾀하였다. 아울러 SWOT 분석을 통해 로고, 명함부터 새로 기획하는 숙명역사관 기프트샵, 인테리어디자인, 디스플레이, 공간연출과 그 안의 제품디자인에 이르기까지 일관성과 통일성을 추구했다. 끝으로 본 연구는 뮤지엄아이덴티티 구축을 위한 창의적 디자인 프로세스를 고찰하며, 이를 바탕으로 개발 매뉴얼을 총체적으로 정리함에 있어서 뮤지엄 브랜딩의 기초 자료로 활용될 것으로 기대된다.

Reappraisal of the Immunogenicity and Safety of Three Hepatitis A Vaccines in Adolescents

Yoon, Seo Hee,Kim, Han Wool,Ahn, Jong Gyun,Kim, In Tae,Kim, Jong-Hyun,Kong, Kyoung Ae,Kim, Kyung-Hyo KOREAN ACADEMY OF MEDICAL SCIENCE 2016 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.31 No.1

<P>Although the overall incidence of hepatitis A in Korea has been decreasing, adolescents remain highly vulnerable to its outbreaks. This study was conducted to compare the immunogenicity and safety of three hepatitis A vaccines in Korean adolescents. Healthy anti-hepatitis A virus seronegative subjects aged 13 to 19 yr were randomized in three equal groups to receive two doses of Avaxim™, Epaxal®, or Havrix®, 6 to 12 months apart. Seroconversion rates one month after the first dose were 98%, 95%, and 93% for Avaxim™, Epaxal®, and Havrix®, respectively. Seroconversion rates reached 100% for all vaccine groups one month after the second dose. Anti-HAV geometric mean concentrations (GMCs) were 7,207.7 mIU/mL (95% CI, 6023.1-8684.7), 1,750.5 mIU/mL (95% CI, 1362.9-2248.3), and 1,953.5 mIU/mL (95% CI, 1459.4-2614.7) after two doses of Avaxim™, Epaxal®, and Havrix® respectively. Avaxim™ was significantly more immunogenic than Epaxal® and Havrix®, whereas there were no significant differences in antibody responses between Epaxal® and Havrix®. Local and systemic solicited adverse events (AEs) were mostly of mild-to-moderate intensity and resolved within 5 days. No serious AEs were reported. In conclusion, all three vaccines are highly immunogenic and well-tolerated in Korean adolescents. (Clinical Trial Registry NCT00483470)</P>

증례 : 혈액종양 ; 유방암의 반대측 재발로 오인된 스파르가눔증

한서애 ( Seo Ae Han ),강병욱 ( Byung Woog Kang ),채의수 ( Yee Soo Chae ),윤준석 ( Jun Seok Yoon ),서상경 ( Sang Kyung Seo ),박호용 ( Ho Young Park ),박지영 ( Ji Yeong Park ) 대한내과학회 2015 대한내과학회지 Vol.89 No.4

저자들은 수술 및 항암 화학 요법을 시행 받고 추적관찰중인 유방암 환자에서 유방암의 재발이 의심되었으나 절제생검을 시행하여 스파르가눔증으로 진단된 예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Sparganosis is a rare parasitic infection caused by plerocercoid tapeworm larvae of the genus Spirometra. While initially asymptomatic, the migrating larvae initially appear as subcutaneous nodules, which can be mistaken for cancer because all parts of the body can be affected, including the abdominal cavity, genitourinary tract, gastrointestinal tract, musculoskeletal system, central nervous system, and even the breasts. Therefore, we report here a case of sparganosis that was differentially diagnosed from recurrence of breast cancer. (Korean J Med 2015;89:470-473)

Uncertain Association between Tenofovir and eGFR Reduction in Patients with Chronic Hepatitis B

( Kwang Il Seo ),( Byung Chul Yun ),( Sang Uk Lee ),( Byung Hoon Han ),( Eun Taek Park ),( Jin Wook Lee ),( Seo Ae Han ),( Dohyeong Lee ),( Sung Jun Kim ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

Aims: Tenofovir disoproxil fumarate (TDF) is known to be associated with nephrotoxicity in patients with human immunodeficiency virus (HIV). TDF is a potent antiviral agent to treat chronic hepatitis B (CHB) infections and the prescription has been increased rapidly in worldwide. Intermittently, nephrotoxicities due to TDF in CHB patients were reported in some cases. Therefore, we have been interested the real-life incidence of renal toxicity in CHB patients treated with TDF. Methods: From January 2012 to December 2014, medical records of patients who had been treated with TDF or entecavir (ETV) in Kosin University Gospel Hospital were reviewed retrospectively, focused on the estimated GFR (eGFR) reduction. Results: A total of 295 patients received TDF or ETV. Twenty-five patients treated for 30 days or less, and 45 patients without follow-up creatinine level were excluded. The following patients were also excluded : baseline eGFR < 60 (ml/min/1.73m2) patients (n = 9), polycystic kidney disease (n = 1), decreased eGFR due to aggravating factor (n = 17). Among 198 patients, 99 received TDF and 99 ETV. In 18 patients, eGFR was reduced by more than 30% compared to baseline. Half of them treated with TDF and the other half with ETV. Baseline eGFR (P=0.006) and age (P=0.015) were significantly correlated with eGFR reduction. The presence of LC (P=0.684), Non-selective beta blocker (P=0.309), type of antiviral agents (P=0.927), and BMI (p=0.965) were not associated with the eGFR reduction. Subgroup analysis of CKD stage 2 (60<eGFR<90) or older than 60 years did not show any significant association between antiviral agents and eGFR reduction. Conclusions: More than 30% reduction of eGFR was observed in 9% CHB patients receiving antiviral agents. Baseline eGFR and age were significantly correlated with eGFR reduction. There was no significant correlation between the type of antiviral agents (TDF of ETV) and the decrease in renal function.

Effects of Respiratory Muscle Activity in Stroke Patients after Feedback Breathing Exercise

Jong Man Han,Hyeon Ae Kim,Ja Pung Koo,Kyo Chul Seo 국제물리치료학회 2013 Journal of International Academy of Physical Ther Vol.4 No.2

The purpose of this study is to examine the effects of feedback breathing exercise on respiratory muscle activity. Thirty stroke patients were randomly and equally assigned to an experimental group and a control group. The experimental group received rehabilitation exercise treatment for 30 minutes and feedback respiratory exercise for 30 minutes and the control group received rehabilitation exercise treatment for 30 minutes and conducted motomed exercise for 30 minutes. All of them conducted exercises five times per week for four weeks. Respiratory muscles including the upper trapezius(UT), longissimus dorsi(LD), rectus abdominis(RA), external abdominal oblique(EAO) and, internal abdominal oblique(IAO) were measured using MP 150WSW prior to and after the experiment. Regarding pulmonary functions prior to and after the experiment, the experimental group showed significant differences in all sections but the control group did not show significant differences in any sections. As for in-between group differences after the experiment, there were significant differences in the UT, LD, RA, and IAO but no significant differences in the EAO. In conclusion, respiratory muscle activity was more effective for the experimental group than the control group. It is considered that feedback respiratory exercise may induce improvement in respiratory muscles in stroke patients through feedback breathing exercise.

신나는 과학놀이 마당 평가 연구

한재영,임혁,최원호,서혜애,조수민,전영석,현종오,류성철,김현빈 한국과학교육학회 2001 한국과학교육학회지 Vol.21 No.3

본 연구는 과학 실험활동을 중심으로 구성된 학교외 과학 행사를 평가하는 데 목적을 두고 있다. 1998년도 '신나는 과학 놀이마당'에 참석한 857명 중 무작위로 표집한 121명의 초· 중등 학생과 행사계획 및 진행을 담당한 72명의 지도 학생과 19명의 지도 교사를 대상으로 사전-사후 설문조사와 관찰을 통하여 프로그램의 평가 결과를 분석하였다. 프로그램에 대한 평가는 1) 행사목표의 달성수준, 2) 행사 구성/운영의 적합성, 3) 행사 진행과정의 효율성, 4) 행사의 사전 안내 및 참석 학생과 지도학생의 참석동기의 세부항목으로 구분하였다. 대부분의 참가학생, 지도학생, 지도교사는 프로그램의 전반에 걸쳐 높은 만족도를 보였다. 평가 결과에 따른 프로그램의 개선점은 참가학생들이 보다 더 적극적으로 참여하는 과학 활동을 제공하고, 탐구력을 더욱 강조하는 활동과 일상 생활과 관련되는 과학 내용을 더 많이 포함하도록 계획되어야 하는 점이다. 또한, 행사에 대한 사전 안내 및 광고를 보다 효율적으로 추진하여야 하며, 지도학생들의 참가학생에 대한 효율적인 학습-교수 전략을 개발하고 지도교사-지도학생간의 상호협력도 향상되어야 할 것이다. The study aimed to evaluate an activity-oriented extracurricular science program as informal science education through the assessment of opinions of student participants and lead-students and lead-teachers who organized the program. An 'Exciting Science Fair' was designed by science teachers and students and provided for 857 students for two days in early 1998. Students chose a course of science activities designed by different levels of student knowledge and interests. During their own science activity courses, the participating students were grouped as pair of two students and guided and facilitated by lead-students. A survey instrument was developed by researchers and asked respondents' opinions of 121 participating students, 72 lead-students, and 19 lead-teachers to the significance of program goals, degree of goal achievement, and program planning and management system before and after the program. It was found that most student participants, lead-students and lead-teachers satisfied with the efficiency of the program. However, it was recommended that the program should place more emphases on engaging student participants in science activities, strengthening scientific inquiry through activities, and increasing science content related to student daily life. It was also suggested that advertizement of the program be publicized in advance through media, an effect teaching-learning strategy for lead-students be developed, and collaboration among lead-students and lead-teachers be improved.

A Fungus-Inducible Pepper Carboxylesterase Exhibits Antifungal Activity by Decomposing the Outer Layer of Fungal Cell Walls

Seo, Hyo-Hyoun,Park, Ae Ran,Lee, Hyun-Hwa,Park, Sangkyu,Han, Yun-Jeong,Hoang, Quyen T. N.,Choi, Gyung Ja,Kim, Jin-Cheol,Kim, Young Soon,Kim, Jeong-Il APS Press 2018 Molecular plant-microbe interactions Vol.31 No.5

Nrf2-mediated induction of detoxifying enzymes by alantolactone present in Inula helenium

Seo, Ji Yeon,Lim, Soon Sung,Kim, Ju Ryoung,Lim, Ji-Sun,Ha, Young Ran,Lee, In Ae,Kim, Eun Ji,Park, Jung Han Yoon,Kim, Jong-Sang John Wiley Sons, Ltd. 2008 Phytotherapy research Vol.22 No.11

<P>Our previous study showed that a methanol extract of Inula helenium had the potential to induce detoxifying enzymes such as quinone reductase (QR) and glutathione S-transferase (GST) activity. In this study the methanol extract was further fractionated using silica gel chromatography and vacuum liquid chromatography, to yield pure compounds alantolactone and isoalantolactone as QR inducers. Alantolactone caused a dose-dependent induction of antioxidant enzymes including QR, GST, &ggr;-glutamylcysteine synthase, glutathione reductase, and heme oxygenase 1 in hepa1c1c7 mouse hepatoma cells. The compound increased the luciferase activity of HepG2-C8 cells, transfectants carrying antioxidant response element (ARE)-luciferase gene, in a dose-dependent manner, suggesting ARE-mediated transcriptional activation of antioxidant enzymes. Alantolactone also stimulated the nuclear accumulation of Nrf2 that was inhibited by phosphatidylinositol 3-kinase (PI3K) inhibitors. In conclusion, alantolactone appears to induce detoxifying enzymes via activation of PI3K and JNK signaling pathways, leading to translocation of Nrf2, and subsequent interaction between Nrf2 and ARE in the encoding genes. Copyright © 2008 John Wiley & Sons, Ltd.</P>

Complete genome sequence and comparative genome analysis of Streptococcus parauberis KCTC11980

Seo, Jung Soo,Kwon, Mun Gyeong,Hwang, Jee Youn,Jung, Sung Hee,Han, Hyun Ja,Kim, Myoung Sug,Do, Jeong-Wan,Park, Myoung Ae,Kim, Dong-Wook,Cho, Wang Sik,Lee, Kyungho Springer-Verlag 2015 Genes & Genomics Vol.37 No.11

Averaged head phantoms from magnetic resonance images of Korean children and young adults

Han, Miran,Lee, Ae-Kyoung,Choi, Hyung-Do,Jung, Yong Wook,Park, Jin Seo IOP 2018 Physics in medicine & biology Vol.63 No.3

<P>Increased use of mobile phones raises concerns about the health risks of electromagnetic radiation. Phantom heads are routinely used for radiofrequency dosimetry simulations, and the purpose of this study was to construct averaged phantom heads for children and young adults. Using magnetic resonance images (MRI), sectioned cadaver images, and a hybrid approach, we initially built template phantoms representing 6-, 9-, 12-, 15-year-old children and young adults. Our subsequent approach revised the template phantoms using 29 averaged items that were identified by averaging the MRI data from 500 children and young adults. In females, the brain size and cranium thickness peaked in the early teens and then decreased. This is contrary to what was observed in males, where brain size and cranium thicknesses either plateaued or grew continuously. The overall shape of brains was spherical in children and became ellipsoidal by adulthood. In this study, we devised a method to build averaged phantom heads by constructing surface and voxel models. The surface model could be used for phantom manipulation, whereas the voxel model could be used for compliance test of specific absorption rate (SAR) for users of mobile phones or other electronic devices.</P>