마비형 뇌성마비환자의 뇌파 및 임상양상

윤여훈,송홍기,김형철,이병철,이숙자 대한신경과학회 1996 대한신경과학회지 Vol.14 No.1

일부 大學敎授와 敎職員의 心血關係疾患 危險要因 및 健康行態에 關한 硏究

윤의성,천병철,박미숙,김순덕,염용태 고려대학교 의과대학 1997 고려대 의대 잡지 Vol.34 No.3

We reviewed the health screening record(1996) of a university to compare cardiovascular risk factors and major health behavior of teaching staffs with those of other staffs. The reviewed cardiovascular risk factors were body mass index (BMI), blood pressure (BP), total cholesterol (TCH) and fasting blood sugar (FBS). Smoking, drinking, exercise and diet habits were cheked as major risk factors. We defined the obesty (BMI>25), hypertension (systolic BP 140 or diastolic BP 90 mmHg), hypercholesterolemia (TCH 230mg/dl), and hyperglucosemia (FBS 110mg/dl) , drinking group (alcohol intake 3-4 times a week and over 1 bottle of soju a time), smoking group (smoking over 10 cigarettes a day), non-exercising group(do excercise below 3-4 times a week, and below 30 min a times), unbalanced diet group(do favor salty and spicy food or do favor flesh food). The 1,341(81.7%) of 1,640 staffs were screened in 1996, the teaching staffs were 614(69.3% of 886 teaching staffs) and other staffs (mainly clerks and administrators) were 737(97.7% of 754). 41 (6.7%) of teaching staffs were female and 166(22.4%) of the other staffs were. Among the teaching staffs, there were no below age 30 but 11.5% of them were over 60; in case of the other staffs 11.3% and 2.0% were in each age group. We divided the teaching staffs into medical staffs and non-medical staffs and compare the risk factors of each group. The total number of screened medical staffs were 92(36.2%) of 254, and non-medical staffs were 522 (82.6%) of 632. The results were follows; 1) The frequency of hypertension of each group were significantly different (7.2% in teaching staff, 11.8% in other staffs) after adjusting sex, age, smoking, drinking, exercise, and diet habits by multiple logistic regression (p<0.001). Hyperglucosemia were founded 10.5% and 12.4% in each staffs and the difference were significant after adjusting age, sex and health habits(p=0.005). Teaching staffs had more hypercholesterolemic persons than other staffs(24.3%, 16.3% in each staffs, p=0.019). Obesity frequency was not significantly different. 2) The number of drinking group were 114(18.6%), 208(28.3%) in each staffs, and this difference were significantly different (CMH=38.295, p=0.001). The number of smoker were 140(22.8%) and 274(37.2%) (CMH=58.109, p=0.001). The frequency of non-exercising group and the frequency of unbalanced diet group were not significantly different. 3) The frequency of obesity were 39.1% and 30.9% in each medical and non-medical staffs (CMH=4.414, p=0.036), but this difference remains non-significant after adjusting by the health habits. The frequency of hyperglucosemia of medical staffs (17.4%) were significantly higher than non-medical staffs (9.2%) after adjusting age, sex and the health habits (p=0.0005). Other risk factors were not significantly different. 4) Medical staffs had more smoker(29.4%) than non-medical staffs(21.5%) (CMH=6.401, p=0.011) and more non-exercising persons (27.2%) then non-medical staffs(11.1%) (CMH=12.446, p=0.001). Other health behaviors are not significantly different.

유지 투석중인 만성 신부전환자에서 허혈성 심질환의진단 지표로서의 심장트로닌-I의 유용성

신병철,강대웅,정지용,류봉관,서영욱,김정인,김범윤,김현리,정종훈 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.1

Background : Coronary disease is highly prevalent in patient with end stage renal disease (ESRD) and account for much of their observed morbidity and mortality. Troponin-I consistently maintains a high sensitivity and specificity and is most sensitive marker for ischemic heart disease (IHD). Method : We examed 49 hernodialyzed patients (22 male, 27 female) without evidence of acute coronary syndrome (ACS) for 6 months. Biochemical markers were measured in serial predialysis blood samples. For analysis, we used two cardio-specific assays for troponin-T (cTnT) as well as for troponin-I (cTnI) and compared the results with CK-MB (reference value ≤ 4.0 ng/mL) concentration. Results : Myocardial ischemia was observed in 47% (23/49) of patients. cTnT level above 0.1 ng/mL. and cTnI level above 0.5 ng/mL, were observed in 22% (11/49) and 20% (10/49) of patients respectively. cTnI revealed significantly higher positive rate in patients with myocardial ischemia than the patients without myocardial ischemia (43 % vs 30%) (p<0.05). cTnT and CK-MB revealed no difference in positive rate between the patients with and without myocardial ischemia (cTnT : 30% vs 15% and CK-MB : 30% vs 19%). The sensitivity and specificity of cTnI to myocardial ischemia were higher than those of cTnT and CK-MB (sensitivity 43% vs 30% and 30%. specificity 100% vs 85% and 81%). Conclusion: Both cTnT and cTnI are useful in ruling out myocardial injury in chronic renal failure patients. But. cTnI is a more sensitivity and excellent specificity of ischemic heart disease than cTnT and CK-MB in hemodialyzed patients. In patients with ischemic heart disease, the presences of DM and advanced age were higher than those in patients without ischemic heart disease (p<0.05). Among the baseline characteristics old age, elevated LDH and diabeties were significant more frequent in the patients with elevation of cardiac troponin-I (p>0.5 ng/mL) than those with cardiac troponin-I (p<0.5 ng/mL), p=0.038, p=0.049, and p=0.045, respectively. Our results suggest that these cTnI is the potential diagnostic marker for the prediction of IHD in ESRD patients.

승모판 대치술후에 발생한 좌심실유출로 폐색 1예

김도연,조홍근,정익모,박시훈,박성훈,신길자,정병철 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.1

T1 강조 영상에서 선조체 고신호강도를 보이는 당뇨 환자에서의 편측무도증

정승철,이병철,김상윤,배재천,황성희,도화범,박종호 대한신경과학회 1997 대한신경과학회지 Vol.15 No.1

장방형내 저온 단일 수평 원관 주위의 동결현상에 관한 실험적 연구

정현철,윤재원,장원택,전승배,이동석,김병철 朝鮮大學校 機械技術硏究所 2007 機械技術硏究 Vol.10 No.1

An experimental study on water in a rectangular cavity with a horizontal cooling tube was carried out to investigate the flow character and thermal behavior in the system. Each experiment was performed with variation of initial temperature and cooling tube temperature. When the cooling tube temperature was -4℃, the supercooling phenomenon was observed regardless of the initial water temperature. And the case of cooling tube temperature was -6℃ with initial temperature was below 4℃, the supercooling phenomenon was also observedin the large region of the test section. When the cooling tube temperature was -10℃, the local region of supercooling phenomenon was observed during the freezing process. And the higher initial temperature was, the higher supercooling degree and the less difference of the ice thickness between upward and downward was observed. It is shown that by controllingthe supercooling phenomena and the cooling tube temperature, it would lead to an increase efficiency of ice making.

수직 냉각면이 있는 정방형내 성층유체의 열적거동에 관한 실험적 연구

정현철,윤재원,장원택,전승배,이동석,김병철 朝鮮大學校 機械技術硏究所 2007 機械技術硏究 Vol.10 No.1

This study was investigated by experimentals on the thermal behavior of stratified fluids in the square cavity with the vertical cooling surface by variation of initial temperature and cooling surface temperature and concluded as follows: 1. When the cooling surface temperature of the square cavity was -4℃. the supercooling phenomena was occurred every times regardless initial temperature of fluids and when -6℃ freezing was begun with out supercooling phenomena. 2. The higher the initial temperature was, the longer supercooling phenomena duration was, and the longer the supercooling phnomena was, the higher the temperature of the upper fluids was. 3. When the supercooling phenomena of water was occurred, the rate of temperature decrease of silicon oil was higher and when there was no supercooling phenomena, it was almost same the rate of temperature decrease.

FET형 CO₂센서의 제조 및 감응특성

이은숙,이영철,정지영,윤종훈,김창수,손병기,이흥락 경북대학교 센서기술연구소 1995 센서技術學術大會論文集 Vol.6 No.1

A FET type micro CO_(2) sensor based on a Severinghaus type arrangement has been prepared and its response characteristics were examined. The sensor was fabricated by formation of hydrogel layer containing bicarbonate/chloride ions on the PH-ISFET and the Ag/AgCl reference electrode prepared by the thermal evaporation and chemical chloridation methods. And then gas-permeable membrane was dip-coated on the hydrogel layer of the sensor. Gas-permeable membranes were fabricated with silicon rubber and polyurethane dissolved in toluene and THF, respectively. The CO_(2) sensor with the silicon rubber membrane showed better sensitivity and lower detection limit than the CO_(2) sensor with the polyurethane membrane for dissolved CO_(2). The sensor with silicon rubber membrane at optimal conditions showed a good response: linear range of 1.60X10^(-4) ~ 4.40X10^(-2) M CO_(2), sensitivity of 57.30 mV/decade, and detection limit of 7.50x10^(-4) M.

피질하 혈관성 치매 환자에서 협착성 뇌혈관 병변의 의의 : 자기공명 혈관조영술과 양전자방출단층촬영을 이용한 연구 MR Angiography and ^(18)FDG-PET Study

유경호,이병철,마효일,김윤중,정지향,나덕렬,강연욱 대한치매학회 2004 Dementia and Neurocognitive Disorders Vol.3 No.1

Background and Objective:Subcortical vascular dementia (SVD) incorporates small vessel disease as the primary vascular etiology, represents in MRI by lacunar infarct and deep white matter lesions. In clinical practice, a number of SVD patients present with various vascular risk factors for large artery disease (LAD) i.e., old age, hypertension, and diabetes. However the current diagnostic criteria for SVD did not include angiographic findings as a key feature. Therefore we tried to find out the frequency of large artery disease in SVD and to elucidate whether the presence of LAD affects clinico-radiological manifestations of SVD. Methods:Thirty three patients fulfilling 'Research criteria for SVD' by Erkinjuntti from 17 study centers were recruited. Of these 33 patients, 21 who underwent comprehensive neuropsychological test battery, MRI ^(18)FDG-PET, and MR angiography were classified into two subgroups according to the patterns of MRI abnormality:white matter dominant (WM) type (n=5) and multiple lacunar (LC) type (n=16). Clinical and neuropsychological profile and ^(18)FDG-PET findings of 21 SVD patients with and without LAD were compared. Results: Twelve (57%) of 21 SVD patients had mild stenotic lesions in intracranial large arteries:4 in middle cerebral artery, 8 in posterior cerebral artery, and 4 in vertebrobasilarj artery. There were no differences in vascular risk factors, characteristics of cognitive dysfunctions, and ^(18)FDG-PET findings between SVD with and without LAD. Conclusions:Our results showed that the presence of mild degree of large artery stenosis did not affect the clinical., neuropsychological profile and cerebral metabolism in PET. Therefore, the current 'Research criteria for SVaD' by Erkinjuntti could be used to diagnose SVD as a homogenous clinical group regardless of angiographic abnormalities.

만성 활동성 간염에 있어서 Ursodeoxycholic acid의 치료효과

김성록,안병철,윤영미,탁원영,곽규식,최용환,정준모 慶北大學校 醫科大學 1991 慶北醫大誌 Vol.32 No.4

The purpose of this study is to evaluate the clinical and biochemical effects of SGD-F^(R)(UDCA, Vitamin B_1, Vitamin B_2 complex) in chronic active hepatitis. Observed cases were given orally after each meal(three times a day) for 4 weeks. The results were as follows: 1. Among subjective symptoms, improvement rate showed in easy fatigability 86.7%, anorexia 68.0%, indigestion 80.0%, nausea and vomiting 72.7%, RUQ pain 83.3%. 2. Biochemical parameters such as SGOT, SGPT, showed to be improved significantly after the 4 weeks treatment.(p<0.01) 3. There was no specific side effect during the study period in all cases. In conclusion, SGD-F^(R) capsule may be safe and effective for chronic active hepatitis.