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( Ki Min Sohn ),( Kwan Ho Jeong ),( Joo Hyun Lee ),( Jung Eun Kim ),( Hoon Kang ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2
Background: Frequency electrical stimulation is clinically being used in variable skin therapeutic conditions such as skin rejuvenation and hair disorder. There have been several clinical studies demonstrating the positive effect of electrical stimuli on hair regrowth. However, its exact mechanism is yet to be clarified. Objectives: The objective of this study is to investigate effects of different electrical parameter settings on hair growth by revealing the changes of dermal papilla cell in vitro and at microscopic level in animal tissue. Methods: Cultured dermal papilla cells (DPCs) and dorsal skin of rabbit were electrically stimulated with different parameter settings at alternating-current to find the optimal condition for hair growth. Cell viability and proliferation were measured by MTT. In addition, Ki67, proliferation marker, expression was measured by immunofluorescence. Hair growth-related gene expression in DPCs and the skin of rabbit were measured by RT-PCR. Results: At certain electrical settings, DPCs responded well and their proliferation was successfully induced. Wnt/β -catenin, Ki67, p-ERK and p-AKT expressions in DPCs increased at certain frequency settings. Dermal thickness and hair related genes (PDGF, VEGF, SOX9 and KGF) expressions in the skin of rabbit also significantly increased. Conclusion: These data suggest that electrical stimulations at certain electrical settings, may give more effective therapeutic outcomes for hair growth.
강호영,김영진,변근주,이기성 연세대학교 산업기술연구소 1988 논문집 Vol.20 No.1
An assessment of cumulative damage of plain concrete subjected to random loading is studied in this paper. Random loading of Beta distribution, which is governed by the mean and standard deviation of peak stresses working on concrete, is applied and the influence of the random loading on the fatigue of plain concrete is analyzed. The relationship among mean of peak stresses, its standard deviaton and fatigue life, the relation between fatigue life and changes in strain, and the one between fatigue life and modified Palmgren-Miner hypothesis are investigated for the random compressive loading on concrete cylinder specimens. From these relationships, a model which may be used to estimate the cumulative damage of concrete structure subjected to random loading of Beta distribution is proposed.
급냉 제강슬래그를 잔골재로 사용한 차폐콘크리트의 공학적 특성에 관한 실험적 연구
강기웅,조성현,정원섭,권기주,김진만,김무한 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)
The steel slag, a by~product which is produced during the manufacture of steel by refining pig iron, is mainly used as road materials after aging it. It is necessary to age steel slag for long time in air because the reaction with water and free-CaO in steel slag could make the expansion of volume. This problem prevents steel slag from being used as aggregate for concrete. However, steel slag used in this study was controled by a air-jet method which rapidly cools substance melted at a high temperature. The rapid-chilling method prevents from generation of free-CaO in steel slag. The rapid-chilled steel slag is similar to be spherical shape and has the heavier specific gravity than natural aggregate. Therefore, it could be used to manufacture radiation shielding concrete as fine aggregate. This paper investigated the engineering properties of radiation shielding concrete when using rapid-chilled steel slag as fine aggregate. As results of this study, the increase of use of rapid-chilled steel slag decreased the desirable water content of concrete but developed the rate of radiation shielding of concrete. The strength of concrete using it is similar to that of concrete using river sand.
한약 탕제분획의 항 Herpes simplex virus 활성에 관한 연구
강봉주,고병섭,양기상,박갑주 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1
Herpes simplex viruses(HSV) are one of the most common infectious virus of man. Though chemotherapies and antiviotics against HSV have been developed in many countries, but anti-HSV agents were not satisfactory to mankind by their toxic reaction and side effects. In order to search for anti-HSV agents from Korean traditional prescriptions, we extended the number of specimens. Both methanol extract and boiling water extract of the Korean traditional prescriptions were screened to detect anti-HSV activities by MTT assay. Korean traditional prescriptions showing anti-HSV activities as methanol extracts were Paekyo˘psan, Chesu˘pwilyu˘ngtang, Yongdamsangantang, and prescription 11. Four methanol extracts showing anti- HSV activities were fractionated by hexane and their efficacies were tested. Hexane fractionations of Paekyo˘psan, Chesu˘pwilyu˘ngtang, and prescription 11 showed in anti-HSV in tissue culture and their selectivity indexes (SI) were 19.50, 3.32 and 42.90, respectively. Methanol fractionation of Paekyo˘psan showed anti-HSV activities and its SI was 1.40. Especially Paekyo˘psan showed anti-HSV activities both haxane and methanol fractionation.
孫基洙,金榮柱,姜昞燮,李壬洙 慶北大學校 1989 論文集 Vol.48 No.-
Depending on structure and electronic resonances the second-order non-linear susceptibility Χ^(2) is usually measured by second-harmonic generation. The macroscopic non-linear optical susceptibility Χ^(2) for a system of partially oriented molecules is written as the ensemble average of molecular hyperpolarizability tensor β. The orientational distribution of these molecules is described by a probability function expanded in Wigner matrices. It confirmed that Χ^(2) has seven non-vanishing conponents for a rotationally invariant system. For a molecule with C_2υ we compared average orientation angle of sum-frequency generation with of SHG, determined elements β_zzz β_xzx of the dominant molecular tensor components and caculated average orientation angle.
권경주,정성애,심기남,정정화,강석형,송도경,전승정,김혜인 이화여자대학교 의과학연구소 2012 EMJ (Ewha medical journal) Vol.35 No.1
Until recently, colorectal polyps were classified predominantly as hyperplastic or adenomatous. While adenomatous polyps are well-characterized precursor lesions of adenocarcinomas, hyperplastic polyps have been considered as benign lesion. However, some hyperplastic polyps with serrated morphology of the crypts have been recognized to have distinctive features and these polyps were termed ‘serrated adenomas’. Recent data show that sessile serrated adenomas (SSA) might be the precursors of serrated colonic cancers, underlining the necessity of identifying them. SSA is approximately 3% of all polyps, commonly appears as flat or sessile and yellowish due to mucus production. In the pathogenesis of SSA, progression to high grade dysplasia or early invasive carcinoma may be associated with serrated neoplasia pathway different from adenoma-carcinoma sequence. We report a case with a colon polyp diagnosed as sessile serrated adenoma with high grade dysplasia after endoscopic submucosal dissection.
W-CDMA를 이용한 PCS 기지국용 RF 송신부의 설계 및 구현
진년강,백주기 단국대학교 1999 論文集 Vol.34 No.-
In this study, the wideband CDMA transmitter for PCS is designed and implemented. As a modulation method, the CC-OQPSK implemented as the ASIC and this modulation method has better spectral and power efficiency than conventional QPSK system because it has constant envelope characteristics. In the intermediate frequency stage using double-conversion scheme, good hamonics rejection characterisitics and gain of 20 ㏈ were obtained. The output power of two-stage RF amplifier is +21.14 ㏈m in 1.9㎓ band. It has been confirmed that the electrical characterisitics of the transmitter which is implemented in the paper satisfy with the specification of wideband CDMA transmitter that has been set to be the design standard of PCS.