90년대 교단학문작품에 나타난 교사성 분석

정한성,정회욱 木浦大學校 敎育硏究所 2002 교육연구 Vol.15 No.-

이 연구의 목적은 90년대 교단문학에 나타난 긍정적인 교사상과 부정적인 교사상을 알아보기 위한 것이다. 교단 문단작품에 나타난 교사상을 분석하기 위하여 1990년에서 2000년 사이의 시, 소설, 수필집, 교단문집 등의 장르에 나타난 교사상을 수집하였다. 분석결과 교단문학에 나타난 긍정적인 교사는 학습기술이 뛰어나고, 학생들의 입장을 이해하고, 특기적성을 신장시켜주고, 사랑과 봉사정신을 가지고 있고, 학생들에게 공정한 대우를 해주고, 유모가 뛰어나고, 젊고 발랄하고, 친절하고 따뜻하고, 부지런히 연구하는 행동적 특성을 보여주는 교사였다. 아울러 부정적인 교사상은 다음과 같았다. 체벌하는 교사, 촌지에 의미를 부여하는 교사, 학생을 이해하지 못하고 편애하거나 편견을 갖는 교사, 모범을 보이지 않는 교사, 정의감이 없는 교사, 학생을 믿지 않는 교사 등이다. The purpose of this study is to know about behavioral characteristic of good and bad teachers described in 'Teacher Literature' in the 1990s. To achieve this purpose, the researchers collected data from poems, novels, essays, magazines. The results of the study are that good teachers have the behavioral characteristics as followings : skillful in teaching, seek to understand students, seek to find and develop students' talents, treat students fairly, good sense of humor, cheerful, friendly and warm-hearted, scholastic etc. And bad teachers have the behavioral characteristics as followings : punish students physically, harsh and cold to students, discriminate students, injustice to students, mistrustful etc.

강원도 사북-고한 지역의 석탄광 폐석에 대한 물리적, 역학적 특성 연구

임한욱,정윤영,목진호,김종훈,김재동,신동오 강원대학교 석재복합신소재제품연구센터 1996 석재연 논문집 Vol.1 No.-

석탄광 폐석의 건설용 골재로서 활용 가능성을 검토하기 위하여 폐석의 주요 구성암석인 사암, 사질혈암, 혈암, 탄질혈암을 대상으로 기초물성실험, 역학적 실험 및 골재원 특성 실험을 실시하였다. 시험결과치의 평균값을 기준으로 할 때 사암, 사질혈암, 혈암은 골재로서 활용이 가능하나, 실험치의 분산도가 심하여 활용가능 폐석과 불가능한 폐석이 혼재되 있음을 확인하였다. 반면에 탄질혈암은 골재원 특성이 가능하나 강도등 물성에서는 사용이 곤란한 것으로 판단되었다. 따라서 앞으로 폐석중 활용가능한 사암, 사질혈암 및 혈암을 효율적으로 분급하는 방안과 금번에 실시하지 못한 골재의 알카리 반응시험 등이 추가로 보완되었으면 한다. An experimental program was undertaken to test rock wastes from coal mines, for use as a new source of aggregate. Physical and mechanical properties, required for aggregate materials, of major constituents of rock wastes including sandstones, sandy shales, shales, and coal shales, were measured in the laboratory. Test results showed that the sandstones, sandy shales and shales tested in this study might possibly be used for construction aggregates, the highly scattered test data indicated considerable proportion of unusable rocks. In case of coal shales, the aggregate characteristics were generally adoptable but some physical properties such as rock strength were lower than required. In conclusion, it is suggested that an effective procedure for sorting the rock wastes, and additional tests such as alkali-aggregate reaction should be supplemented.

저빈도 반복성 경두개 자기자극이 정상인의 시각적 단기 기억에 미치는 영향

오해정,김원,이경욱,박원명,전태연,한진희,채정호 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.5

Objectives : Repetitive transcranial magnetic stimulation (rTMS) is a novel, noninvasive method of brain stimulation. Since conventional rTMS does not cause seizure, marked advantage over electroconvulsive therapy (ECT), rTMS can be used easily and widely. Once the effects of rTMS on cognitive function are elucidated, its application will be further extended. However, the effects of rTMS on cognitive function have not been well examined. This study aimed to evaluate the effect of low frequencyr TMS on visual short term memory. Methods : Forty normal healthy volunteers were randomly assigned to rTMS (n=20) or sham (n=20) groups. The rTMS group were again randomly divided into left prefrontal (n=10) and right prefrontal (n=10) groups. For each group rTMS was given at 1 Hz for 20 minutes with 100% of motor threshold. As a cognitive task, Corsi Block Tapping Test (CORSI) in the computerized Vienna Test System, which can assess visual short term memory, was performed before, during, and after the rTMS. Results : No significant difference was found in the visual short term memories between the rTMS and the sham groups before, during, or after 1 Hz rTMS, nor between the left and right prefrontal rTMS groups. Conclusion : This study demonstrates that rTMS, contrary to ECT, has no adverse visual short term memory effect when used as the standard treatment paradigm. Therefore, rTMS could be a new and safe treatment method in various neuropsychiathc fields without any interference of cognitive function.

Multiple myeloma 환자에서 Bortezomib치료 후 발생한 마비성 장폐색증 1례

김준영,이원식,손창학,박성길,진한영,박석주,조영완,정은욱,강명주,박정하,주영돈 인제대학교 2006 仁濟醫學 Vol.27 No.-

Bortezomib is the first clinically available proteasome inhibitor that is clinically effective in the treatment of multiple myeloma. A proteasome inhibitor acts through multiple mechanisms to arrest tumor growth, tumor spread, and angiogenesis. The main adverse effects of bortezomib are gastrointestinal symptoms, cytopenia, fatigue, and peripheral neuropathy. To date, severe paralytic ileus has not been reported as a toxic effect of bortezomib treatment in multiple myeloma. Bortezomib is a novel agent that has only been used clinically for 30 months, so a need exists to further evaluate its toxicity. We report a case of grade Ⅲ (NCI CTCAE v3.0) or grade Ⅳ(SWOG toxicity criteria) paralytic ileus in a 65-year-old man with relapsed multiple myeloma who underwent one cycle of single-agent bortezomib treatment scheduled in a 21-day cycle (1.3 mg/㎥ as a single i.v. bolus on days 1, 4, 8, and 11).

마우스 종양발생에서 Nitric Oxide의 역할에 관한 연구 Ⅲ : Helicobacter pylori에 의해 유발된 마우스 위암에서 염증매개인자의 역할 The role of inducible nitric oxide synthase and cyclooxygenase-2 in H. Pylori-associated gastric carcinogenesis

남기택,오상연,조현무,이국경,강진석,제정환,최미나,한상욱,김대용,장동덕,양기화,안병우 식품의약품안전청 2001 식품의약품안전청 연보 Vol.5 No.-

feficotorfer fyf☞ri(Hp)가 위암파 관련이 있다는 역학적인 증거는 많이 있지만 이에 대한 정확한 기전에 대해선 밝혀져 있지 않고 있으며 실험동물 모델도 적절하지 못한 것으로 알려져있다. 본 실험에서는 위암의 원인으로 알려져 있는 f, fyforf'(Hp)를 이용하여 마우스에서 위암 모델을 확립하고 만성염증과정 중에 생성되는 리0와 COX-2 등의 발현이 위암발생에 미치는 명향을 통하여 예방과 치료를 위한 점근을 시도하고자 하였다. 마우스를 7군으로 나누어서 1, 2, 3, 4군의 등물은 MNU를 증류수에 200ppm 농도로 음수병득 이용하띤 10주간 격주로 투여하였으며 MHU 음술 투여 1주 휴씩 후 배양한 f. fyrofi 를 약 109cru/rfll 로 맞춰 한 마리당 0.1ml 씩 이틀 간격으로 세 번에 걸쳐 하룻방 금식시킨 1, 2, 3, 5, 6, 7군기 마우스의 위장에 투입하떴다. 균 투입을 마친 후 다응 날부터 2군쏙 6군은 iNOS 억제제인 aminoguanidine(AG)을 음수병으로 툰여하였으며 3군과 7군은 COX-2 척제제인 nimesulide(NSD)를 투여하였다. 위의 종양발생양상을 샅최보면 bfNU와 Hp만을 투여한 1 관 ; (hfNU +Hp), 2군 : iNO을 inhibitor 투여군(MNU+HP+AG'1. 3군 ;CO딘-2 Inilibitor 투여군(MNU누Hp누 NSD), 4군 ,MNlf 단독투여군, 5군 ;Hp 단독투여춘, 6군 ; 러p 단독에 AG투여군, 7군 , Hp 단독에 NSD투여군의 종양발샐을은 각각 쁜.Bff(l1/16), 70.6%f12/ti), 했.9ff(7/18), 10%(1/10), Off(O/IS)0%(O/S), 0%(O/5)의 발쟁율을 보여 iNOS 억제제인 AC은 좁양발생을 억계하지 못하였으며, COX-2억제제인 NSD 는 종양발생을 유의적으로 감소시켰다. 콩양발생개수에서는 2.62±0.36, 1.41츠0.14, 0.44 르0.12, 0.10±0.10을 보여 AC와 NSD에서 유의성 있게 발생개수를 줄였다. Hp 단독투여에 의해즌는 종양발생이 나타나지 않았으며 HP+AG, Hp+ IfSD 추여군에콕 시험증료 시점에 약물에 의해 Hp의 제균효과가 있는지의 여부를 확인끓기 위하여 PCR을 이용하여 확인한 결과 모두 양성인 것으로 나타나 Hp의 제균효과에 의한 촐양발생 억제가 일어나지는 않았다. 위의 결과로 볼 때 Hp는 위암발생을 촉진하는 것으로 나타났고 딘p 감염시 매개되는 염증인자를 억제하였을 때 종양발생을 억제하는 것으로 위암 발생에서 염증매개인자는 종양을 촉진하는 것으로 나타났으며 it,705 억제제쓱 COX-』 억제제의 위알 예밭효과fl는 효과적일 것으로 사료된다 In spite of a large volume of epidemiological evidence indicating significant relationship between H. pylori infection and gastric adenocarcinoma, a doubt still exists on an elevated risk of stomach cancer by H. pylori infection due to lack of direct evidence of their exact mechanistic link. It is, therefore, essential to have an appropriate animal model for detailed analysis of the role of H. pylori played in gastric carcinogenesis. There is a wealth of evidence to support that over production of inducible nitric oxide synthase(iNOS) and cyclooxygenase-2(COX-2) is involved in the pathogensis of various cancer in both rodents and humans. The aim of this study was to establish a mouse model for H. pylori-associated gastric carcinogenesis and to identify the role of inducible nitric oxide synthase(iNOS) and cyclooxygenase-2(COX-2) played during the gastric carcinogenesis in mice. Eighty-three specific pathogen free, six-week-old male C57BL/6 mice were randomly divided into seven groups. Animals of the group 1, 2, 3, 4 were given MNU in their drinking water at the concentration of 200 p.p.m. for total five cycles of one-week regimen with one-week pause. After completion of MNU administration, they were given autoclaved distilled water for one weeks, and groups 1, 2, 3, 5, 6, 7 were inoculated with H. pylori. After completion of H. pylori. inoculation, groups 2 and 6 were given aminoguanidine in their drinking water at concentration of 1000p.p.m. and animals of group 3 and 7 were given the diet containing 200 ppm nimesulide at 12 weeks of age. All animals were killed at 50 weeks of age. The incidences of the glandular stomach tumors in the group 1, 2, 3 and 4 were 87.5%(14/16), 76.4%(13/17), 44.4(8/18), 10.0%(1/10), respectively and the tumor incidence of group 3(MNU→Hp+nimesulide) was significantly lower than those of group 1(MNU→Hp) at the value of P<0.01. The average numbers of tumors of group 2(MNU→Hp+AG : 1.41±0.24) and group 3(MNU→Hp+nimesulide : 0.44±0.12) were significantly lower than those of group 1(MNU→Hp : 2.62±0.36) at the value of P<0.05. Therefore, overproduced iNOS and COX-2 plays an important role in mice gastric carcinogenesis. We concluded iNOS and COX-2 inhibitor have good effects on gastric carcinogenesis.

Ultra-precision turning and interferometric testing process for KAONICS optical parts

Han Jeong-Yeol,Yuk In-Soo,Lee Sungho,Kim Sug-Whan,Han In-Woo,Cha Sang-Mok,Jin Ho,Park Soojong,Nam Uk-Won,Kim Geon-Hee,Yang Ho-Soon 한국우주과학회 2005 한국우주과학회보 Vol.14 No.1

Editorial : Train-of-Four monitoring: overestimation

( Jeong Uk Han ) 대한마취과학회 2011 Korean Journal of Anesthesiology Vol.60 No.5

Comparison of clinical characteristics between never-smokers and ever-smokers in female lung cancer patents: Evaluation of Korean Central Cancer Registry Data

( Jeong Uk Lim ),( Chan Kwon Park ),( Solji Han ),( Chang Min Choi ),( Chi Young Jung ),( Deog Gon Cho ),( Jae Hyun Jeon ),( Jeong Eun Lee ),( Jin Seok Ahn ),( Yeongdae Kim ),( Yoo-duk Choi ),( Yang-g 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.-

Purpose: The aim of this study was to compare clinical characteristics and prognosis between never and ever-smokers in female patients with lung cancer using nationwide registry in Korea. Materials and Methods: The Korean Association for Lung Cancer developed a registry in cooperation with the Korean Central Cancer Registry, and surveyed about 10% of lung cancer cases. For this first survey of cases diagnosed in 2014, cases were selected through a systematic sampling method. Results: Total of 2,621 lung cancer patients were surveyed and 744 female lung cancer patients were selected. After excluding 8 patients without data on smoking history, 736 patients were evaluated in this study. Among them, 644 (87.5%) were never-smokers, and 92 (12.5%) were ever-smokers. Median survival was compared between the two groups: median survival was not reached for the never smoker group, while it was 14.9 months for the ever-smoker group (P<0.001). During the study period, there were 635 non-small cell lung cancer (NSCLC), and 52 small cell lung cancer (SCLC). Among 635 NSCLC patients, 569 patients were never-smokers and 66 patients were ever-smokers. The ever smoker NSCLC group had significantly lower proportion of stage I patients and EGFR mutation when compared to the never-smokers (27.3% vs 41.7%, P=0.004, and 34.2% vs 50.3%, P=0.001, respectively). Among 469 patients with NSCLC, epidermal growth factor receptor (EGFR) mutation group (n=230) had higher proportion of clinical stage I (40.4% vs 29.1%, P=0.03), and patients who received targeted therapy as 1st line treatment (30.7% vs 1.8%, P<0.001) than wild-type group (n=239). From multivariable analysis for survival in 269 stage IV NSCLC patients, receiving only supportive care, and EGFR wild-type were significant predictors for shorter survival. Conclusion: From this nationwide cancer registry data, majority of female lung cancer patients were never-smokers, and showed different clinical characteristics and prognosis compared to ever-smoker patients.

Editorial : The success of periclavicular brachial plexus block

( Jeong Uk Han ) 대한마취과학회 2010 Korean Journal of Anesthesiology Vol.58 No.3

Preliminary design of optical and opto-mechanical part for receiving telescope of Satellite Laser Ranging system

Han jeong-Yeol,Jang Jeong-Gyun,Han Inwoo,Mihn Byeong-Hee,Lim Hyung-Chul,Park Jong-Uk 한국우주과학회 2005 한국우주과학회보 Vol.14 No.2