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Yang, Hyeri,Kim, Da-eun,Jang, Won-Hee,An, Susun,Cho, Sun-A,Jung, Mi-Sook,Lee, Ji Eun,Yeo, Kyung-Wook,Koh, Sang Bum,Jeong, Tae-Cheon,Kang, Mi-Jeong,Chun, Young-Jin,Lee, Su-Hyon,Lim, Kyung-Min,Bae, Seun Pergamon 2017 Toxicology in vitro Vol.39 No.-
<P><B>Abstract</B></P> <P>Here, we report the results of a prevalidation trial for an <I>in vitro</I> eye irritation test (EIT) using the reconstructed human cornea-like epithelium, MCTT HCE™. The optimal cutoff to determine irritation in the prediction model was established at 35% with the receiver operation characteristics(ROC) curve for 126 substances. Within-lab(WL) and between-lab(BL) reproducibility was tested for 20 reference substances by 3 participating laboratories. Viability data described by mean±SD or ±1/2 difference between duplicate wells, and scatter plots, demonstrated the WL/BL consistency. WL/BL concordance with the binary decision, whether non-irritant or irritant was estimated to be 85–95% and 95%, respectively. WL/BL reproducibility of viability data was further supported by a strong correlation(ICC, <I>r</I> >0.9). WL/BL agreement of binary decisions was also examined by Fleiss' Kappa statistics, which showed a strong level of agreement (>0.78), nevertheless weaker than the reproducibility of the viability. The EIT with MCTT HCE™ exhibited a sensitivity of 82.2% (60/73), a specificity of 81.1% (43/53), and an accuracy of 81.8% (103/126) for 126 reference substances (for liquids; a sensitivity of 100% (47/47), a specificity of 70.6% (24/34), and an accuracy of 87.7% (71/81), and for solids, a sensitivity of 50% (13/26), a specificity of 100% (19/19), and an accuracy of 71.1% (32/45), suggesting that the accuracy is satisfactory but the sensitivity needs improvement, which shall be addressed through correcting the poor sensitivity for solid substances in future full validation trials.</P> <P><B>Highlights</B></P> <P> <UL> <LI> MCTT™ HCE EIT employing water-soluble formazan WST-1, demonstrated a performance comparable to other RhCEs. </LI> <LI> Within- and between-lab reproducibility for 3 labs with 20 chemicals were 85–95% and 95% respectively. </LI> <LI> Predictive capacity for 126 chemicals was sensitivity 82.2%, specificity 81.1% and accuracy 81.8% </LI> </UL> </P>
Mesoscopic Network를 이용한 딥페이크 감지 기법
이혜리 ( Hyeri Lee ),양희규 ( Huigyu Yang ),추현승 ( Hyunseung Choo ) 한국정보처리학회 2022 한국정보처리학회 학술대회논문집 Vol.29 No.1
소셜 미디어와 스마트폰의 대중화로 인해 디지털 이미지와 비디오를 만들어 내는 일이 매우 흔해졌다. 전통적인 이미지 포렌식 기술 압축 방법은 데이터를 손상시킨다는 점에서 비디오에 적용하기 부적절하다. 따라서 본 논문에서는 딥러닝과 MesoNet을 이용한 모델을 통해 참 혹은 거짓만 나타내는 기존의 결과 산출 방법에서 더 나아가 네가지의 분류 방법으로 딥페이크 감지 흐름을 살펴보고자 한다.
고혜리(Hyeri Ko),양은경(Eunkyung Yang) 한국콘텐츠학회 2017 한국콘텐츠학회논문지 Vol.17 No.8
본 연구는 한국 사회에서 ‘남성 아이돌 그룹’의 여성혐오 논란과 이를 둘러싼 팬덤 내부/외부의 담론을 고찰함으로써 한국 사회에서 여성들이 겪고 있는 내적 갈등과 외적 대립의 과정을 확인하고자 했다. 연구결과, 방탄소년단 팬덤으로 대표되는 여성들이 팬덤 외부의 문제 제기로 인해 여성혐오에 대한 자신의 인식에 대해 성찰한 것, 그리고 스타에 대한 비난을 원천 봉쇄하고 비판 자체를 터부시하던 기존 팬덤의 성격에서 벗어난 것은 방탄소년단 여성혐오 논란에서 얻어낸 긍정적 의의라고 볼 수 있다. 그러나 유동적이고 모호한 기준 아래 팬덤을 페미니즘에 방해가 되는 존재로 규정하고 이들의 의견을 억압하고 폄하하는 과정이 수반 되었다고 볼 수 있다. 여성혐오 논쟁에서 여성들이 자기혐오와 갈등의 과정 끝에 숨어버리거나, 자신의 의견과 취향을 사회로부터 용인 받지 못하거나, 페미니즘 자체에 대한 불편한 감정을 가지며, 또 다른 혐오의 재생산으로 이어질 수 있는 가능성들에 주의를 기울일 필요가 있다. This research examines the impact of Korean boy group’s misogyny issue leading to internal conflicts among female fans and external division. As a result of research, BTS’s fans who are mostly female reflected their identities by problem posed by external stakeholders on this issue. In the past, most fandoms tried to protect themselves from criticism but this case shows a positive significance since they broke out from stereotypical cases. Under the vague and flexible standard, fandom can be considered the obstructing factor for Feminism which suppress and denounce Feminists’ idea. It is important to pay attention to possibilities of females hide at the end of the conflict process, being unaccepted by the society for their opinions and tendencies, have uncomfortable emotion against Feminism itself, or Feminism leading to another type of aversion.
Hamelo Shewangzaw,Yang Jihye,Song Hyeri,Oh Seungjae,Lee Hanju 한국물리학회 2022 새물리 Vol.72 No.12
With the advancement in technology, forgers further improve their methods to create more accurate forgeries. Although various techniques have been used to detect forged banknotes, the use of microwave spectrum in detecting forged banknotes is a relatively new research area. In this study, we investigated the application of microwave energy in detecting forgeries on banknotes. The proposed method was based on the thermoelastic optical indicator microscopy technique, which visualized the distribution of microwave near-fields. The Korean banknotes of 1000 won, 5000 won, and 10,000 won, and their corresponding scanned samples were selected, and the distribution of microwave near-field was measured. Our results showed a strong distribution of the microwave magnetic near-field on the hologram at 12 GHz for 5000 won and 10,000 won, and the field distribution of the corresponding scans was different. On the other hand, the microwave near-field distribution of the 1000 won and its scan showed a similar distribution.
Analysis of Statistical Methods Currently used in Toxicology Journals
Jihye Na,Hyeri Yang,SeungJin Bae,Kyung-Min Lim 한국독성학회 2014 Toxicological Research Vol.30 No.3
Statistical methods are frequently used in toxicology, yet it is not clear whether the methods employed by the studies are used consistently and conducted based on sound statistical grounds. The purpose of this paper is to describe statistical methods used in top toxicology journals. More specifically, we sampled 30 papers published in 2014 from Toxicology and Applied Pharmacology, Archives of Toxicology, and Toxicological Science and described methodologies used to provide descriptive and inferential statistics. One hundred thirteen endpoints were observed in those 30 papers, and most studies had sample size less than 10, with the median and the mode being 6 and 3 & 6, respectively. Mean (105/113, 93%) was dominantly used to measure central tendency, and standard error of the mean (64/113, 57%) and standard deviation (39/113, 34%) were used to measure dispersion, while few studies provide justifications regarding why the methods being selected. Inferential statistics were frequently conducted (93/113, 82%), with one-way ANOVA being most popular (52/93, 56%), yet few studies conducted either normality or equal variance test. These results suggest that more consistent and appropriate use of statistical method is necessary which may enhance the role of toxicology in public health.
양윤모 ( Yunmo Yang ),오다연 ( Dayeon Oh ),김대현 ( Daehyun Kim ),이대희 ( Daehee Lee ),길기범 ( Gibeom Kil ),조윤해 ( Yoonhae Cho ),이혜리 ( Hyeri Lee ),천세억 ( Seok Cheon ),채민희 ( Minhee Chae ) 한국환경분석학회 2018 환경분석과 독성보건 Vol.21 No.3
To evaluate the overall level of pollution in surface sediments of weir-constructed sections in the Geum River, samples were collected at nine sites four times during the period from 2015 to 2016 (a total of 36 samples). Particle size distribution, organic matter, nutrients, and heavy metals were analyzed. The surface sediments were composed mainly of sand, and the sediment types were S (sand), zS (silty sand), and sZ (sandy silt). The concentrations of IL, T-N, and T-P were lower than the values of the class IV sediment pollution evaluation level (National Institute of Environmental Research standards). The results showed that the research sites were not severely or apparently not polluted by organic matter and nutrients. The pollution assessment and ecological risk of heavy metals were evaluated using various geochemical assessment indices (I<sub>geo</sub>, EF, mPEL<sub>k</sub>Q, and PLI). Our results indicate that there was anthropogenic pollution in the study area, moderately polluted especially by Cd and Zn.
Analysis of Statistical Methods Currently used in Toxicology Journals
Na, Jihye,Yang, Hyeri,Bae, SeungJin,Lim, Kyung-Min Korean Society of ToxicologyKorea Environmental Mu 2014 Toxicological Research Vol.30 No.3
Statistical methods are frequently used in toxicology, yet it is not clear whether the methods employed by the studies are used consistently and conducted based on sound statistical grounds. The purpose of this paper is to describe statistical methods used in top toxicology journals. More specifically, we sampled 30 papers published in 2014 from Toxicology and Applied Pharmacology, Archives of Toxicology, and Toxicological Science and described methodologies used to provide descriptive and inferential statistics. One hundred thirteen endpoints were observed in those 30 papers, and most studies had sample size less than 10, with the median and the mode being 6 and 3 & 6, respectively. Mean (105/113, 93%) was dominantly used to measure central tendency, and standard error of the mean (64/113, 57%) and standard deviation (39/113, 34%) were used to measure dispersion, while few studies provide justifications regarding why the methods being selected. Inferential statistics were frequently conducted (93/113, 82%), with one-way ANOVA being most popular (52/93, 56%), yet few studies conducted either normality or equal variance test. These results suggest that more consistent and appropriate use of statistical method is necessary which may enhance the role of toxicology in public health.
중심정맥관과 관련하여 미숙아에서 발생한 심장압전 2례 보고
양세령 ( Se Ryung Yang ),신훈범 ( Hoon Bum Shin ),이나미 ( Na Mi Lee ),이대용 ( Dae Yong Yi ),김혜리 ( Hyery Kim ),윤신원 ( Sin Weon Yun ),채수안 ( Soo Ahn Chae ),임인석 ( In Seok Lim ),최응상 ( Eung Sang Choi ) 대한주산의학회 2015 Perinatology Vol.26 No.3
Although central catheter-related complications are frequently reported and are inevitable in the neonatal care unit, the incidence of pericardiac tamponade is low but may be fatal. Index of suspicion, prompt diagnosis, and urgent pericardiocentesis are crucial for lifesaving. We encountered two premature cases of central venous catheter-related pericardial tamponade. The first case was a 4-day-old male premature infant (gestational age [GA], 33+5 weeks; birth weight [BW], 1,864 g), and the second case was a 4-day-old female premature infant (GA, 28+6 week; BW, 1,050 g). Each infant had an indwelling central venous catheter since birth and at the third day of hospitalization. The conditions of the babies suddenly deteriorated, but both babies were successfully resuscitated with urgent echocardiography and prompt pericardiocentesis.