Development of a Media DNA direct dPCR Method for Cytotoxicity Testing

Ah Leum Kim,Hye Ji Shin,Ji Youn Lee,Young-Kyung Bae 한국분석과학회 2023 학술대회논문집 Vol.2023 No.11

Bronchoscopic Ethanolamine Injection Therapy in Patients with Persistent Air Leak from Chest Tube Drainage

( Ah Leum Lim ),( Cheol Hong Kim ),( Yong Il Hwang ),( Chang Youl Lee ),( Jeong Hee Choi ),( Taerim Shin ),( Yong Bum Park ),( Seung Hun Jang ),( Sang Myeon Park ),( Dong Gyu Kim ),( Myung Goo Lee ),( 대한결핵 및 호흡기학회 2012 Tuberculosis and Respiratory Diseases Vol.72 No.5

Background: Chest tube drainage (CTD) is an indication for the treatment of pneumothorax, hemothroax and is used after a thoracic surgery. But, in the case of incomplete lung expansion, and/or persistent air leak from CTD, medical or surgical thoracoscopy or, if that is unavailable, limited thoracotomy, should be considered. We evaluate the efficacy of bronchoscopic injection of ethanolamine to control the persistent air leak in patients with CTD. Methods: Patients who had persistent or prolonged air leak from CTD were included, consecutively. We directly injected 1.0 mL solution of 5% ethanolamine oleate into a subsegmental or its distal bronchus, where it is a probable air leakage site, 1 to 21 times using an injection needle through a fiberoptic bronchoscope. Results: A total of 15 patients were enrolled; 14 cases of spontaneous pneumothorax [idiopathic 9, chronic obstructive pulmonary disease (COPD) 3, post-tuberculosis 2] and one case of empyema associated with broncho-pleural fistula. Of these, five were patients with persistent air leak from CTD, just after a surgical therapy, wedge resection with plication for blebs or bullae. With an ethanolamine injection therapy, 12 were successful but three (idiopathic, COPD and post-tuberculosis) failed, and were followed by a surgery (2 cases) or pleurodesis (1 case). Some adverse reactions, such as fever, chest pain and increased radiographic opacities occurred transiently, but resolved without any further events. With success, the time from the procedure to discharge was about 3 days (median). Conclusion: Bronchoscopic ethanolamine injection therapy may be partially useful in controlling air leakage, and reducing the hospital stay in patients with persistent air leak from CTD.

정비예정구역 해제지역 재생사업의 정비요소와 고령거주자의 사업 만족도 간의 영향관계 사례연구

김아름(Kim, Ah-Leum),구자훈(Koo, Ja-Hoon) 한국주거학회 2016 한국주거학회 논문집 Vol.27 No.5

The purpose of this study is to establish the determinants of satisfaction with the results of housing regeneration projects among their elderly residents, and to suggest the political implications. The survey included questionnaires about satisfaction levels with the projects’ physical and non-physical maintenance factors. The results were statistically analyzed by correlation analysis and PLS regression analysis. As a result of the study, firstly, the physical factors rather than nonphysical factors (such as home improvement and management support, community support, the economic foundations and professional support) were found to have a large effect on elderly residents’ satisfaction. Secondly, the non-physical factors, such as economic factors were analyzed among senior job offers that are both highly influential in the two regions Yonnam-dong and Bukgajwa-dong. Finally, electrical maintenance work, tree planting, a “Green” parking plan, or refuse the effect of visually larger landscape improvement, such as bins installed, maintenance of local factors that contribute to the greenery of the area were judged to be important.

SURF 기법을 활용한 위성 SAR 다중해상도 영상의 정합 및 기하보정

김아름 ( Ah Leum Kim ),송정환 ( Jung Hwan Song ),강서리 ( Seo Li Kang ),이우경 ( Woo Kyung Lee ) 대한원격탐사학회 2014 大韓遠隔探査學會誌 Vol.30 No.4

위성 SAR 영상의 활용이 증가하면서 영상의 해석 및 융합을 위한 정밀 기하보정에 대한 필요성이 높아지고 있다. 특히 광역감시 목적으로 활용되기 위해 서로 다른 해상도를 갖는 SAR 영상간 정보융합도 활발해지고 있다. 일반적으로 SAR 영상의 기하보정은 위성의 궤도 및 자세정보를 활용하여 수행할 수 있지만 SAR 센서의 궤도 및 시스템 오차, 대상지형 특성에 의한 왜곡으로 인해 추가적인 보정이 필요하게 된다. SAR 영상을 통한 변화탐지나 타 영상과의 융합에 적용하기 위해서는 기하 오차 보정이 반드시 선행되어야 한다. 이를 위해 다수의 지상 기준점을 선정하고 이를 포함하는 기준 영상과 비교하여 원본 영상에서 대응점을 찾는 방식으로 정밀 기하보정을 수행할 수 있다. Speeded Up Robust Feature (SURF) 기법은 쉽고 빠르게 영상의 기준점을 찾을 수 있지만 상대적으로 해상도가 낮고 스펙클 잡음에 영향을 받는 SAR 영상에서는 활용하기가 어렵다고 알려져 있다. 본 논문에서는 SURF 기법을 위성 SAR 영상에 적용할 때 발생할 수 있는 오차를 추출하고 영상 특성에 따른 성능 변화를 분석하였다. SURF 알고리즘의 적용이 가능한 입력 변수의 적정 범위를 제시하고 그에 따른 영상 정합의 오차를 분석하여 중저해상도의 위성 SAR 영상에 대해서도 SURF 기법을 통한 기하 보정 및 영상 정합이 적용될 수 있음을 검증하였다. As applications of spaceborne SAR imagery are extended, there are increased demands for accurate registrations for better understanding and fusion of radar images. It becomes common to adopt multi-resolution SAR images to apply for wide area reconnaissance. Geometric correction of the SAR images can be performed by using satellite orbit and attitude information. However, the inherent errors of the SAR sensor`s attitude and ground geographical data tend to cause geometric errors in the produced SAR image. These errors should be corrected when the SAR images are applied for multi-temporal analysis, change detection applications and image fusion with other sensor images. The undesirable ground registration errors can be corrected with respect to the true ground control points in order to produce complete SAR products. Speeded Up Robust Feature (SURF) technique is an efficient algorithm to extract ground control points from images but is considered to be inappropriate to apply to SAR images due to high speckle noises. In this paper, an attempt is made to apply SURF algorithm to SAR images for image registration and fusion. Matched points are extracted with respect to the varying parameters of Hessian and SURF matching thresholds, and the performance is analyzed by measuring the imaging matching accuracies. A number of performance measures concerning image registration are suggested to validate the use of SURF for spaceborne SAR images. Various simulations methodologies are suggested the validate the use of SURF for the geometric correction and image registrations and it is shown that a good choice of input parameters to the SURF algorithm should be made to apply for the spaceborne SAR images of moderate resolutions.

Bronchoscopic Ethanolamine Injection Therapy in Patients with Persistent Air Leak from Chest Tube Drainage

Lim, Ah-Leum,Kim, Cheol-Hong,Hwang, Yong-Il,Lee, Chang-Youl,Choi, Jeong-Hee,Shin, Tae-Rim,Park, Yong-Bum,Jang, Seung-Hun,Park, Sang-Myeon,Kim, Dong-Gyu,Lee, Myung-Goo,Hyun, In-Gyu,Jung, Ki-Suck,Shin, The Korean Academy of Tuberculosis and Respiratory 2012 Tuberculosis and Respiratory Diseases Vol.72 No.5

Background: Chest tube drainage (CTD) is an indication for the treatment of pneumothorax, hemothroax and is used after a thoracic surgery. But, in the case of incomplete lung expansion, and/or persistent air leak from CTD, medical or surgical thoracoscopy or, if that is unavailable, limited thoracotomy, should be considered. We evaluate the efficacy of bronchoscopic injection of ethanolamine to control the persistent air leak in patients with CTD. Methods: Patients who had persistent or prolonged air leak from CTD were included, consecutively. We directly injected 1.0 mL solution of 5% ethanolamine oleate into a subsegmental or its distal bronchus, where it is a probable air leakage site, 1 to 21 times using an injection needle through a fiberoptic bronchoscope. Results: A total of 15 patients were enrolled; 14 cases of spontaneous pneumothorax [idiopathic 9, chronic obstructive pulmonary disease (COPD) 3, post-tuberculosis 2] and one case of empyema associated with broncho-pleural fistula. Of these, five were patients with persistent air leak from CTD, just after a surgical therapy, wedge resection with plication for blebs or bullae. With an ethanolamine injection therapy, 12 were successful but three (idiopathic, COPD and post-tuberculosis) failed, and were followed by a surgery (2 cases) or pleurodesis (1 case). Some adverse reactions, such as fever, chest pain and increased radiographic opacities occurred transiently, but resolved without any further events. With success, the time from the procedure to discharge was about 3 days (median). Conclusion: Bronchoscopic ethanolamine injection therapy may be partially useful in controlling air leakage, and reducing the hospital stay in patients with persistent air leak from CTD.

달 탐사 위성의 통신 링크 분석

김아름(Kim Ah Leum),이상민(Lee Sang Min),이우경(Lee Woo Kyung) 한국통신학회 2009 한국통신학회 학술대회논문집 Vol.2009 No.6

Bronchoscopic injection of absolute ethanol in patients with persistent air Leak from chest tube drainage

( Ah Leum Lim ),( Cheol Hong Kim ),( In Gyu Hyun ) 대한내과학회 2011 대한내과학회 추계학술대회 Vol.2011 No.-

Bronchoscopic injection of absolute ethanol in patients with persistent air leak from chest tube drainage

( Ah Leum Lim ),( Cheol Hong Kim ),( In Gyu Hyun ) 대한내과학회 2011 대한내과학회 추계학술대회 Vol.2011 No.1

Background: Chest tube drainage (CTD) has indicated for the treatment of pneumothorax, hemothroax and after thoracic surgery. But, in the case of incomplete lung expansion and/or persistent air leak from CTD, medical or surgical thoracoscopy or, if that is unavailable, limited thoracotomy should be considered. We evaluate the efficacy of bronchoscopic injection of absolute ethanolamine to control persistent air leak in patients with CTD. Methods: Patients who had persistent or prolonged air leak from CTD were included consecutively. We directly injected 1.0 ml aliquots of ethanolamine into a subsegmental or its distal bronchus where is probably air leakage site, 1 to 20 times using injection needle through a fiberoptic bronchoscope. Results: 15 patients (all men) were enrolled. There were 14 spontaneous pneumothorax (5 idiopathic, 6 chronic obstructive pulmonary disease (COPD) and 3 post-tuberculosis) and 1 empyema associated with broncho-pleural fistula in the study. Of 14 patients with ethanolamine injection therapies, five had previous surgical therapy, wedge resection for bullae, but the others didn`t have. Twelve were successfully treated by an ethanolamine injection therapy alone. But three (idiopathic, COPD and post-tuberculosis) were failed and followed by a surgery (2 cases) or pleurodesis (1 case). Minor complications such as fever, chest pain and transient pneumonic infiltrations occurred after the therapy. With successful, the time to discharge was about 3 days (median). Conclusions: Bronchoscopic ethanolamine injection therapy may be partially useful in controlling air leakage and reducing the hospital stay in patients with CTD.

High mobility group box-1 and inflammatory cytokines in follicular fluid of patient with Endometriosis

( Minkyoung Kim ),( Jae Hoon Lee ),( Jung Mi Yoon ),( Ah Leum Kim ),( Seok Kyo Seo ),( Sihyun Cho ),( Young Sik Choi ),( Byung Seok Lee ),( Bo Hyon Yun ) 대한산부인과학회 2016 대한산부인과학회 학술대회 Vol.102 No.-

목적: The aim of the study was to examine the inflammatory status of follicular fluid in endometriosis by detecting High mobility group box-1 (HMGB-1) and inflammatory cytokines, which reflect the milieu of oocyte that may play a role for infertility. 방법: Total 60 patients who had received in vitro fertilization and embryo transfer (IVF-ET) from March, 2013 to March, 2016 were included: 30 patients who had endometriosis as case group, 30 participants without endometriosis as the control. Follicular fluid (FF) was obtained from a dominant follicle during oocyte retrieval and stored at -70°C. Level of HMGB-1 was measured with ELISA, as well as inflammatory cytokines including Interleukin (IL)-1β, IL-6, IL-8, and tumor-necrosis factor (TNF)-α. 결과: Level of HMGB-1 was significantly higher in FF samples from the endometriosis group compared to the controls. IL-6, IL-8, and TNF-α levels were significantly higher in the endometriosis group compared to those in the control. There were significant positive correlations among the four inflammatory cytokines. The levels of the inflammatory cytokines positively correlated with the levels of HMGB-1 in the FF samples. TNF-α levels were negatively correlated with the cumulative embryo score per embryo. Logistic regression analysis revealed that the number of high-quality embryos was an independent factor predicting clinical pregnancy. 결론: This study showed that HMGB-1 and inflammatory cytokines may play an important role through NF-kB pathway, in inflammatory cascade affecting oocyte milieu.

주민참여형 주거지 재생사업에 대한 고령거주자의 사업 만족도 결정요소 연구 - 연남동 사업지구를 대상으로 -

김아름,구자훈,Kim, Ah-Leum,Koo, Ja-Hoo 한국주거학회 2014 한국주거학회 논문집 Vol.25 No.5

The purpose of this study is to estimate the determinants of Elderly Residental Satisfaction on the residential environment improving projects and suggest the political implications. The survey include questionnaires about the satisfaction level on the project physical and non-physical maintenance factors. The results were statistically analyzed by Correlation Analysis and Regression Analysis. As the result of the study, firstly, it shows that 'traffic and improve pedestrian environment' and 'improved parking environment' factors that are important to the satisfaction of the elderly residents of a high impact on the business component a physical maintenance. Secondly, it shows that 'home improvement and management support' and 'economic foundation' factors that are important to the satisfaction of the elderly residents of a high impact on the business component a non-physical maintenance. The results of analysis on the determinants of Elderly Residental Satisfaction on the residential environment improving projects of Yonnam project may be important foundation for future strategies for improvement.