일개 지역에서 b형 헤모필루스 인플루엔자 뇌수막염 예방접종을 하게 되는 경로

사은주,이동욱,성낙진,박기흠 東國大學校醫學硏究所 2007 東國醫學 Vol.14 No.1

We aimed to investigate people's recognition of immunization for Haemophilus influenza type b(Hib) meningitis, their knowledge of the vaccination as an option, the resources for parents, and the effective measures of promoting vaccination rate. From April 20th to May lOth, 2006, we assessed children who visited either a public health center or an university hospital for scheduled vaccination. We analyzed their general characteristics, vaccination rate for Hib, and resources for parents by using the self-written questionnaires. Furhermore, ingestigator rechecked the questionnaire by one-on-one interview. Among the collected self-written questionnaires, the adequately answered cases for the study were conducted by 95 parents from public health center group and 95 from university medical center group. 77 children (81.1%) received vaccination at public health center and 79 children (81.4%) at university medical center. 133 parents (69.3%) had the knowledge of Hib vaccination and as an optional injection, 52 parents (27.1%) knew about the vaccination but without the immunization awareness as an option, and 7 parents (3.6%) did not even know the Hib vaccination itself. Out of 156 children who underwent the vaccination, most parents of 87 (56%) obtained the resources on Hib vaccination from their baby check booklets. Despite the fact that the Hib immunization is an optional vaccine, almost all of people still seek for the Hib vaccination. The good use of baby check booklets would be a significant tool for immunization awareness. 5세이하 소아들의 보호자들이 b형 헤모필루스 인플루엔자 뇌수막염(이하 Hib) 예방접종에 관해 알고 있는지, 이 접종이 선별접종임을 알고 있는지, 또 어떤 경로로 접종하고 있는지를 조사하여 접종률을 올릴 수 있는 방안을 모색해 보고자 이 조사를 시행하였다. 이 연구는 2006년 4월 20일부터 5월 10일까지 서로 인접한 일개시의 보건소 및 대학병원에서 기본접종을 위해 내원한 15개월 이상의 소아들을 대상으로 조사하였다. 미리 구성한 자기기입식 설문지를 이용하여 일반적 특성, Hib 예방접종의 접종률 및 접종경로 등을 조사하였다. 이후에 조사자가 설문지 내용을 1:1 면담으로 다시 확인하였다. 그 결과 Hib 예방 접종을 시행한 경우는 보건소에서 조사한 95명 중 77명(81.1%),대학병원에서 조사한 97명 중 79명(81.4%)이었다. Hib 예방접종이 선별접종임을 아는 경우는 133명(69.3%)이었으며 Hib 예방접종은 알고 있지만 선별접종임을 모르는 경우가 52명(27.1%), Hib 예방접종 자체를 모르는 경우는 7명(3.6%)이었다. Hib 예방접종을 시행한 156명 중 Hib 예방접종을 알게 된 경위가 아기수첩을 보고 알게 된 사람이 87명(56%)으로 가장 많았다. Hib 예방접종이 선별접종임에도 불구하고 대다수에서 접종을 하고 있으며 아기수첩의 적절한 활용이 예방접종률을 높이는데 중요한 수단이 될 수 있다.

한국 수출제조기업의 마케팅역량이 수출성과에 미치는 영향 : 시장지향성과 인터넷 마케팅 효과를 중심으로

강낙중,송은주 국제무역학회 2003 국제무역연구 Vol.9 No.2

시장지향성과 성과와의 관계를 고찰한 문헌은 묵시적으로 시장지향성이 강한 기업이 그렇지 않은 기업에 비해 상대적으로 마케팅 역량이 뛰어날 것으로 전제하고 있다. 그러나 시장지향성과 성과와의 관계속에 내생변수로 존재하는 마케팅 역량을 고려한 연구는 국내에서 거의 전무한 실정이다. 이러한 사실에 착안하여 본 연구는 수출제조기업의 시장지향성이 수출성과에 미치는 영향을 분석함에 있어 마케팅 역량을 내생변수로 하는 모형을 검증하면서, 최근 새롭게 대두된 인터넷 마케팅과 기업규모의 영향을 고려한 연구모델을 설정하였다. 60개 한국 수출제조업체들을 대상으로 한 분석결과, 시장지향성은 마케팅 역량에 정의영향을 미치는 것으로 나타났으며 인터넷 마케팅은 이러한 관계를 강화시키는 것으로 나타났다. 한편 마케팅 역량은 수출성과에 정의 영향을 미치는 것으로 나타났으나 기업규모의 중재역할은 유의하지 않은 것으로 분석되었다. Despite the recognition of the importance of international operations for firms' survival and growth, almost no empirical research has been devoted to examining the relationships between market orientation and export performance. In addition, although firms have been rapidly integrating the internet into their marketing activities, no empirical research has focused on the potential mediating role of internet marketing on the consequences of market orientation. Also, although some research has related finns' distinctive marketing competencies to their strategic typology, none has attempted to relate marketing competencies to market orientation. Under these circumstances, this study construct a synthesized model of market orientation, marketing competence, and export performance, focusing on the mediating roles of internet marketing and firm size m these relationships. Then data for this study were collected from 60 export manufacturing finns in Korea and suitable statistical methodologies were employed for analysis.

유방암의 뇌하수체 전이에 의한 양안 시력소실 1 예

최낙원,안명주,김재민,박동우,박용욱 한양대학교 의과대학 2000 한양의대 학술지 Vol.20 No.1

Pituitary gland metastasis is a rare clinical diagnosis, usually made in the setting of known primary systemic cancer with widespread metastasis to other organs. But visual loss as a presenting symptom of metastasis to the pituitary gland is unusal. We report here a case of 45-year-old woman who had been diagnosed as having metastatic breast cancer involving bone and liver 2 years ago, and received high dose chemotherapy with peripheral blood stem cell transplantation, developed sudden bilateral complete visual loss. At initial presentation, the patient had no light perception and no pupillary response to light in both eyes, but without evidence of panhypopituitarism, or diabetes insipidus. Brain MRI showed a large enhanced mass invasion to the cavernous sinus and extension to the suprasella portion without dura or base-of-skull metastasis. Pathologic examination showed metastatic breast cancer. Despite the transsphenoidal decompression surgery of metastatic tumor, the visual loss was not improved.

地盤 掘鑿時의 地盤앵커에 의한 近接 構造物의 沈下 抑制 效果

강낙안,공영주,주인곤,임종철 釜山大學校生産技術硏究所 1996 生産技術硏究所論文集 Vol.50 No.-

지하구조물의 건설을 위한 깊은 굴착으로 인해 근접구조물에 많은 피해가 발생하고 있다. 피해를 일으키는 주된 원인은 흙막이 벽체의 수평변위에 의한 지반침하와 지하수위 저하나 진동등에 의한 압밀, 다짐 발생에 따른 지반침하 등이다. 지금까지 대부분의 연구는 현장계측을 이용하였으므로, 벽체의 변위와 지반침하에 영향을 미치는 많은 인자들 각각의 영향을 밝히기는 대단히 어려웠다. 본 연구에서는 실내 모형실험을 통하여 최종 굴착시의 주동파괴면 안쪽에 놓여있는 구조물의 침하를 최소화할 수 있는 지반앵커(1단, 2단)의 위치 및 간격을 결정하였다. 실험결과, 앵커 1단 설치, 앵커 2단 설치의 경우가 모두 앵커 깊이 비=0.4∼0.5일 때, 근접구조물의 침하가 최소가 되었다. 또, 지반 굴착시의 지반변형을 관찰하여 위의 사실을 확인하고, 지반 파괴면의 위치 및 형상을 구하였다. The structure is often deformed and damaged by deep excavation. This deformation and damage are mainly made by ground settlement(consolidation, compaction) owing to groundwater drop or vibration etc. and lateral movement of retaining wall. Then, most studies about deformation of ground have done by using results of site measurement, so it was very difficult to find each effect of many factors separately. The purpose of this study is to decide the location and interval of ground anchor( lst, 2nd ground anchor) to be able to minimize the settlement of adjacent structure located inside the active failure surface by model test at laboratory. As results of this model test, it was known that the depth ration of anchor to minimize the settlement of near-by structure was 0.4∼0.5, and by the observation of ground deformation during excavation, the direction and magnitude of displacement and the failure line could be known.

장생도라지의 약리작용

성낙주,서종권 경상대학교 농업자원이용연구소 1998 심포지엄 자료집 Vol.1998 No.1

도라지 (길경, Platycodon grandiflorum A. DC)는 예부터 천식, 기관지염 등에 효능이 인정되어 약용 및 식용으로 널리 이용되어 왔다. 장생 도라지에 대한 연구로 식이성 고혈압 흰쥐에 도라지 분말을 각 5%와 10% 함유한 식이를 3주간 급이하였을 때 혈청과 간장의 지질 농도가 현저하게 감소하였으며, 5%의 도라지 분말 함유 식이의 급이시 도라지를 급이하지 않은 군에 비하여 혈청과 간장의 총콜레스테롤과 중성지질의 농도가 현저하게 감소하였고, alloxan minihydrate를 체중 kg당 15 mg의 농도로 3주간 복강내 주사하여 당뇨를 유발시킨 흰쥐에 6년근과 22년근 도라지 추출물의 급이시 혈당 및 혈청과 간장의 지질 개선에 효과가 있었고, 또한 항암효과에 관한 연구로는 도라지 추출물을 B16-F1 mouse melanoma 세포에 처리해 laminin의 결합력을 실험한 결과 0.125 mg/ml 이상의 농도에서는 100%저해능을 보였으며, mice에 있어서 고형암의 무게를 61.5% 감소시켰으며 sacoma-180 ascites에 대한 생존일수 연장율이 128%에 달하는 것으로 관찰되었다. 도라지의 에탄올 추출물을 극성을 달리한 용매로 분획하여 각 획분의 항균성을 실험한 결과 23년근 도라지의 부탄올획분의 M. luteus에 대한 초소저해농도는 3년근에 비하여 28배나 더 낮은 값을 보였으며, 이를 실리카겔 칼럼 그로마트그래피와 HPLC를 이용하여 에틸아세테이트획분의 항균물질을 분리·정제한 결과 데틸아세테이트획분보다 S. epidermidis에 대해 2∼3배 더 강한 항균력이 관찰되었고 23년근 도라지의 주요 항균물질을 동정한 결과 giycerol linolate임이 확인되었다. The root of Platycodon grandiflorum (p.g.) A. DC (Platicodi radix) has been prescribed frequently for cough and bronchitis as an expectorant in a traditional oriental medicine, and used as a food. Diet-induced hyperlipidenic rats were fed diets containing 5% and 10% p.g (twenty-three years). powder for 3 weeks, the p.g. feeding markedly decreased both serum and liver lipid concentrationds in hyperlipidemic rats. Especially, 5% p.g. diet significantly decreased the concentrations of total cholesteril and triglycerides in serum and liver as compared with those of thr hyperlipidemic control group. The effects of the feeding p.g. (6 or 22 years) extract on the blood glucose, lipids in the serum and liver of alloxan induced hyperglycemic rats (S.D. strain, ♂), alloxan monohydrate 15㎎/㎏ B.W./day, I.P. injection for 3 weeks. concentrations of blood glucose were significantly higher in the allozan administration groups than those in the control group. When p.g. extracts treated in vitro with B16-F1 mouse melanoma cell lines, it showed 100% laminin-binding inhibitory activities at the concentration over 0.125 mg/ml in vivo test it showed 61.5% reduction of the solid tumor weight transplanted in mice and exhibited anticancer activity of 128% ILS against sarcoma-180 ascites. The ethanol extract of p.g. was fractionated by various solvents with different polarities, and the antibacterial activities of each fraction were tested. The minimal inhibitory concentration (MIC) values of each graction of Platycodi radix (twenty-three years) ethanol extract was lower than that of Platycodi radiz (three years) ehanol extract. the MIC value of Platycodi radix(twenty-three years) butanol fraction against M. luteus was 28 times lower than that of Platycodi radiz (three years) butanol fraction. The antibacterial compound was isolated and purified from the ethylacetate fraction by silica gel column chromatography and HPLC, and exhibited 2 to 3 times more antibacterial activity against S. epidermidis than ethylacetate fraction. The major antibacterial compound of Platycodi radix (twenty-three years) was identified to be a glycerol linolate.

人間化敎育을 위한 敎授-學習

柳珞柱 광주대학교 1987 광주개방대학 논문집 Vol.4 No.-

The Humanization Education is never the epochal task which we emphasize on only in our current society. If we look back upon the past education history, we can point out the real case that ancient thinkers in the west had emphasis on the harmonious development of both bodies and spirits. In order to normalize the education, it is necessary to utilize the various learning ways we can build up the higher intelligence through the human relationship between teacher and student, student and student, such as Inquiry Learning, Creative Learning, Non-Directive Learning, Problem solving Learning, Reflextive thinking Learning. And we have to change the view of evaluation like giving marks, deciding the rank into stuent's self-achivement, success of lesson, so that we could get the materials to plan the next lesson. I conclude that the concept of Humanization Education and the improved ways of education evaluation make the school education more valuable and meaningful.

마분말과 천마분말이 흰쥐의 간, 뇌 및 신장의 지질성분 변화에 미치는 영향

박필숙,성낙주,박미연 동아시아식생활학회 1999 동아시아식생활학회지 Vol.9 No.2

The present study tested to recommend optimum level of Gastrodia rhizoma and effect on the compositional changes of the lipids in Sprague Dawley rats which were fed control diet adding 5, 10, 15% Dioscorea batatas powder and 5, 10, 15% Gastrodia rbizoma powder for 3 weeks, respectively, The contents of moisture, ash, fat, protein and carbohydrate in dried Gastrodia rbizoma were 5.9, 2.7, 2.1, 0.9 and 88.4%(w/w) respectively. Concentrations of total cholesterol and free cholesterol in liver were the lowest in the 10% Gastrodia rbizoma group. Concentrations of triglyceride and phospholipid in liver were lower in the 10 and 15% Gastrodia rhizoma groups than in the other groups. Concentrations of total cholesterol, free cholesterol, triglyceride and phospholipid in brain were significantly lower in the group 6, 7 compared to the other groups. Concentrations of triglyceride and phospholipid in kidney were slightly lower in the Gastrodia rhizoma groups than those in the Dioscorea batatas groups.

천마분말이 고콜레스테롤혈증 흰쥐 혈청의 지질성분에 미치는 영향

박미연,성낙주,신정애,이수정,박필숙 동아시아식생활학회 1998 동아시아식생활학회지 Vol.8 No.1

This study was designed to investigate the optimum recommendation level on Gastrodia rhizoma and the effects on the improvement of the lipids in the dietary hypercholesterolemic rats. Experimental diets mixed with 5% Dioscorea batatas(Group 2), 10% Dioscorea batatas(Group 3), 15% Dioscorea batatas(Group 4), 5% Gastrodia rhizoma(Group 5), 10% Gastrodia rhizoma (Group 6) and 15% Gastrodia rhizoma(Group 7) were administered to the male rats of the Sprague Dawley for 3 weeks. Concentration of total cholesterol in serum was lower in the Gastrodia rhizoma groups than in the other groups, especially total cholesterol concentration of 10% Gastrodia rhizoma(Group 6) was the lowest in the Gastrodia rhizoma groups. Concentration of HDL-cholesterol in serum was higher in the 10% Gastrodia rhizoma and 15% Gastrodia rhizoma than in the other groups. Concentrations of cholesterylester, LDL, LDL-cholesterol in serum were the lowest in the 10% Gastrodia rhizoma. Concentration of glucose and activity of GPT in serum were the lowest in the 10% Gastrodia rhizoma group. The activity of GOT in serum was lower in the 10% Gastrodia rhizoma group and 15% Gastrodia rhizoma group than in the other groups. Therefore, we consider that there are effects on the improvement of the lipids in the Gastrodia rhizoma and the optimum recommendation quantity of Gastrodia rhizoma is 10% to quantity of food composition.

폴리에스테르 모르타르용 충전재로서 금속광산 폐광미의 활용 연구

윤성진,최낙운,문경주,소양섭 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

The purpose of this study is to examine the basic properties of polyester mortars using fine tailing(FT) as a filler. The FT is obtained by centrifugal separation of tailing(TA), and checked for basic properties of shape, particle size distribution, chemical composition, resin absorption. Polyester mortars with FT and ground calcium carbonate(GC) are tested for working life, flexural and compressive strengths. The test results showed that FT has much the same properties as GC in the shape, size and resin absorption. The working life of the polyester mortars is lengthen with an increase in the filter/binder ratio. The polyester mortars with a filter/binder ratio of 1.0 have the maximum flexural and compressive strengths.

꽃새우 乾製品의 맛成分 : 1. 유리아미노酸의 變化 1. Changes of Free Amino Acids in Trachypenaeus curvirostris During Sun Drying

李惠淑,金奉玉,成洛珠,鄭承鏞 진주여자전문대학 1981 論文集 Vol.3 No.-

Changes of free amino acids a s taste compounds during sun drying of shrimp Trachypenaeus curvirostris, were analyzed by amino acid autoanalyzer. Glycine, arginine, proline and alanine were dominant amino acids in fresh extracts, having 44.8%( 6109.9㎎%, on dry base), 21.9% (2989.3㎎%), 10.4% (1418.3㎎%)and 5.9% (805.1㎎%) of the total amino acids, respect-ively. Free amino acids were not changed in composition during sun drying of shrimp. Glycine, arginine, proline and alanine were dominant in both fresh extracts and dried products. In dried extracts,.such amino acids as glycine, arginine, proline and alanine were 44.7% (4162.3㎎%, on dry base), 24.1% (2244.61119 %), 11.7% (1090.l㎎%)and 5.3% (495.8㎎%) of the total amino acids, respectively. It is believed that glycicne, arginine, proline and alanine may play an important role as taste compounds in sun dried shrimp.