公務員의 職務滿足度에 관한 小考 : 論山郡 18 個 郵遞局을 中心으로

배덕전 충남대학교 행정대학원 1984 行政硏究 Vol.3 No.-

국가지리정보체계와 환경정보의 통합방안 -환경부의 환경주제도 및 승인통계를 중심으로

조덕호,배민기 대구대학교 환경기술연구소 2005 미래환경기술 Vol.1 No.2

The goal of this study is to suggest the integration method of National Geographic Information System(NGIS) and the environmental theme map and attribute data in order to promote the utilization of geographic information system. In order to do that, this study reviews the characteristics of NGIS and environmental information. After that, it links two database using the administrative unit code. More specifically, this study focuses on the Gyeongbuk province and Gumi city because the volume of the national database is too big to handle it. The result of this study can be applied to any other database which has geographic codes. Ultimately, it can improve the reality of most of analysis using these database because this method can provide most of the database with the locational information

熟地黃의 效能 중 補血作用에 대한 文獻的 硏究

鄭德震,徐榮培 대전대학교 한의학연구소 2001 혜화의학회지 Vol.9 No.2

1.《Graphical Materia Medica》 is first book that writes about Rehmanniae Radix Preparat. 《Shen nong's herbal》 is only written about Rehmanniae Radix. 2.After the 《Decoction Materia Medica》, orintal dortors use Rehmanniae Radix's effect is removing heat from the blood and Rehmanniae Radix's effect is enriching the blood. 3.Rehmanniae Radix Preparat is kinds of durgs for enriching the blood, because Rehmanniae Radix Preparat's effect do nourishing yin and supplementing blood. Therefore, Rehmanniae Radix Preparat is uesd simple recipe or Rehmanniae Radix Preparat is used with another herbs that shows so good effect of hematogenous functions at laboratory work. 4.Bone marrow is doing hematogenesis. That has relation to Rehmanniae Radix Preparat's effect is replenishing bone marrow, it's channel tropisms are liver·kidney channels. 5.Rehmanniae Radix Preparat's guide component is 5-HMF, but effective component has relation with hematogenesis is mannitol of saccharides. And we need more reserch about Rehmanniae Radix Preparat.

인슐린 세포사멸 억제활성과 FAK/p130 Cas 신호전달과의 관계

박덕배 제주대학교 생명과학연구소 2003 제주생명과학연구 Vol.6 No.1

The focal adhesion kinase (pp125FAK) is a nonreceptor tyrosine kinase involved in integrin-mediated signal transduction pathway which includes the activation of' the Ras/mitogen-activated protein (MAP) kinase cascade. Tyrosine phosphorylation of FAK is essential to its activity, as interference with FAK phosphorylation results in apoptotic death in various cellular systems. Insulin receptor has the ability to suppress apoptotic death mediated by growth factor withrawal using signal pathways which is dependent on protein farnesylation. In the present study, we investigated the impact of FAK tyrosine phosphorylation in two responses of insulin: (1) Ras/MAP kinase activation, and (2) Prevention of apoptosis. To this purpose, we examined whethei@ insulin can mudulate FAK activity together with p130Cas, which is a downstream component of FAK signaling. It was also investigated whether insulin can protect cells from apoptosis in CHO IR/△SOS cells. lacking the intrinsic function of mSOS1-Ras activation. Unexpectedly, insulin decreased the degree of tyrosine phosphorylation of FAK as well as pl30Cas where it protected cells from apoptosis both in wild (CHO-IR) and mSOS-Ras-deficient (CHO-IR/△SOS) cells. These results suggest that neither the Ras activity nor FAK activity play role in antlapoptotic protection by insulin. We also tested the ability of other survival factor (DPI) or death factor (TNF-α) to affect insulin's function to dephosphorylate p130Cas or to protect cells from apoptosis. Neither of them could affect tyrosine phosphorylation of p130Cas without regards to their antiapoptotic- and proapoptotic activities, respectively. Taken together, it is suggested that FAK/p130Cas signaling does not play any significant role(s) in insulin's antiapoptotic protection.

중학생의 그래프 능력과 논리적 사고력 및 과학 탐구 능력의 관계

김태선,배덕진,김범기 한국과학교육학회 2002 한국과학교육학회지 Vol.22 No.4

본 연구의 목적은 그래프를 작성하고 해석할 수 있는 중학생의 능력을 알아보고, 그래프 능력과 논리적 사고력 및 과학 탐구 능력의 관련성을 분석하여 효과적인 수업전략과 교사의 교수 행동에 대한 시사점을 얻는 데 있다. 중학생 481명을 대상으로 그래프 능력검사지를 이용하여 중학생의 그래프 능력을 알아보고, 논리적 사고력 검사지와 과학 탐구 능력 검사지를 이용하여 그래프 능력과 논리적 사고력 및 과학 탐구 능력의 상관관계를 조사하였다. 그래프 능력과 논리적 사고력 및 과학 탐구 능력의 상관관계를 조사한 결과, 변인 통제 논리와 비례 논리가 그래프 능력과 관련이 깊은 것으로 나타났다. 그리고 그래프 능력은 논리적 사고력 및 과학 탐구 능력과 대부분 유의한 정적 상관을 보이지만, 통계적으로 상관은 낮았다. 이러한 연구 결과에 비추어볼 때, 앞으로 과학 교사는 중학생의 그래프 능력을 향상시키기 위해 그래프의 중요성을 인식하고, 학생들이 그래프를 작성하고 해석할 수 있는 능력과 변인 통제 논리, 비례 논리 등 논리적 사고력을 향상시킬 수 있도록 체계적인 노력과 효과적인 수업전략이 필요하다고 본다. The purpose of this study was to investigate the relationships of graphing abilities to logical thinking and science process skills of middle school students. The subjects for this study were selected 481 students form four middle schools for TOGS(the Test of Graphing in Science), GALT(Group Assessment of Logical Thinking) and TIPSⅡ(Test of integrated Process Skills). This study shows that the correlation coefficient between abilities of students to construct/interpret graphs and the logical thinking was 0.45, and the correlation coefficient between abilities to construct/interpret graphs and science process skills are 0.32. As a result, abilities of students to construct and interpret graphs are more correlate the logical thinking than science process skills.

설치류 뇌에서 c-Fos를 이용하여 삼투조절과 관련된 신경회로의 규명

이영기,박덕배,장가용 제주대학교 생명과학연구소 2000 제주생명과학연구 Vol.3 No.-

본 연구는 생쥐의 중추신경계통에서 고장액에 반응하여 c-Fos에 대한 면역양성을 나타내는 지역을 규명하고자 수행하였다. c-Fos의 발현은 면역조직화적으로 검출하고 신경세포의 활성화에 대한 표식자로 이용하였다. 고장액은 생쥐 뇌의 supraoptic nuclus, median preoptic nucleus organum vasculosum lamina terminalis, sufornical organ, locus coeluleus, nucleus of solitary tract, ventrolateral medulla, parabrachial nucleus 등에서 발현되었다. 특히 retrochiasmatic area의 배쪽 부분에서 많은 c-Fos면역양성의 세포가 관철되었으며, 시상하부의 paraventricular nucleus나 두뇌의 area postrema에서는 c-Fos면역양성세포가 거의 관철되지 않았는데 이들 지역들은 흰쥐에서는 다수의 c-Fos면역양성 세포가 나타나는 지역이다. 이상의 결과들은 생쥐에서 고장액이에 의해 c-Fos면역양성 세포가 나타나는 지역은 흰쥐에서와는 일부 상이한 결과를 보여주는 것으로 나타났다. Experiments were carried out on adult mouse to investigate the regional localization of the cells inducing c-Fos immunoreactivity in central nervous system in response to hypertonic saline(HS). c-Fos induction, detected immunohistochemically, was regarded as a marker for neuronal activation. Intraperitoneal injection of HS resulted in dense c-Fos-like immunoreactivity (FLI) in several forebrain and brainstem area. These areas include the supraoptic nucleus(SON), median preoptic nucleus (MnPO), organum vasculosum lamina terminalis(OVLT), subfornical organ(SFO), locus coeruleus(LC), nucleus of solitary tract(NTS), ventrolateral medulla(VLM), and parabrachial nucleus(PBN). In particular, the ventral region of retrochiasmatic area showed numerous and very intensely labeled FLI cells. No FLI or few FLI cells were, however, detected in the hypothalamic paraventricular nucleus (PVN) and the area postrema(AP) respectively, the regions which revealed very intensive FLI in rat after HS treatment. These data suggest that FLI induced in response to osmotic stimuli in the mouse brawn has a different regional distribution from that of rat brain.

최대 운동후 면역 기능의 반응

최용어,박덕배 韓國體育大學校 1998 論文集 Vol.21 No.-

This study rearches how graded maximal exercise has an effect on the university handball atheletes group and the general individuals group before exercise, after exercise and in the recovering two hours through cellic immunoreaction. Graded maximal excercise has been done by means of treadmill, applying Bruce protocol which was practised by male university students to see what difference there is between the athelete group and general individual group. The following is the results of comparing and analyzing the immunoreaction of the drawn blood before exercise, after exercise and in recovering two hours. 1. When graded maximal exercise is done, total white blood cells increase more after exercise for both the athlete group and the general individual group. And they are inclined to increase continously in the recovering two hours. Statistically there is no meaningful difference between them. 2. When graded maximal exercise is done, neutrophils increase more after exercise than before exercise for both the athlete group and the individual group. And they are inclined to increase continously in the recovering two hours. Statistically there is no meaningful difference between them. 3. When graded maximal exercise is done, lymphocytes increase more after exercise for both the athletes group and the general individuals group. For the athletes group, lymphocytes increase continously in the recovering two hours. But for the general individuals group, lymphocytes are inclined to come to stability as usual. Statistically there is no meaning difference between them. 4. When graded maximal exercise is done, monocytes increase more after exercise than before exercise. And they continue to increase in the recovering two hours for the athletes group. Monocytes decrease after exercise, but they are inclined to increase in the recovering two hours. Statistically there is no meaningful difference between them. 5. When graded maximal exercise is done, natural killer cells increase more after exercise than before exercise. And they continue increasing in the recovering two hours for both the athletes group and the general individuals group. Statistically there is no meaningful difference between them. All the above results being considered, the graded maximal exercise make immune cells change a lot. It is suggested that especially lymphcytes and natural killer cells can be a factor which enforces human body immunity function.

다시마 푸코이단추출물과 지질대사의 연관성

강금석,남천석,김인덕,권륜희,이동찬,허예영,하배진 신라대학교 자연과학연구소 2007 自然科學論文集 Vol.16 No.-

The effects of Laminaria japonica fucoidan extract (LJFE) on the biochemical parameters of lipid-related function were investigated in liver and serum of CCl_(4)-treated rats. LJFE of 100 mg/kg concentration was intraperitoneally administered into rats at dose of 1.5 ml/kg for 14 days. On the day 15, 3.3 ml/kg of CCl_(4) dissolved in olive oil (1:1) was injected 12 hours before anesthetization. We examined the lipid-related functions and enzyme activitys by measuring the levels of total cholesterol (TC), triglyceride (TG), alkaline phosphatase (ALP) and lactate dehydrogenase (LDH) in serum. The results showed that CCl_(4) treatment increased the high values of TG, LDH and ALP decreased the low values of TC but LJFE pretreatment decreased the high values of TG, LDH and ALP to the low values, increased the TC. It was suggested that LJFE can be used as the potential candidate for the lipid-metabolism natural supplement.

노인틀니 보험급여를 위한 건강보험재정추계연구

권호근,김영남,정기호,송근배,박덕영 대한구강보건학회 2003 大韓口腔保健學會誌 Vol.27 No.3

The purpose of this study is to estimate the National Health Insurance budget needed for the Korean elderly's denture service coverage. For more exact estimating the budget, denture need and demand were calculated by using 2000 National Oral Health Survey data. The results were summarized as follows ; 1. Over 65 years old, full denture and partial denture need per arch were each 8.5% and 16.8%. And over 70 years old, those were each 11.3% and 17.8%. 2. Over 65 years old, full denture and partial denture demand per arch were each 22.8% and 21.2%. And over 70 years old, those were each 27.%% and 21.1%. 3. Based on the denture need, the health insurance budget needed in the first operative year was about 955.4 billion won, over 65 years old and about 644.2 billion won, over 70 years old. 4. Based on the denture demand(wear), the health insurance budget needed in the first operative year was about 207.5 billion won, over 65 years old and was about 151.6 billion won, over 70 years old. If health insurance policy of elderly's denture service coverage is performed, actual denture wear rate is going to increase, and the budget needed is also increasing. Because current National Health Insurance budget status is poor, it is difficult to execute health insurance coverage for elderly's denture service. Therefore we suggest that health insurance coverage for preventive service is to be considered in order to reducing denture need in the long term view.

한국전자제조기업에서의 경쟁전략, 경쟁우선순위의 전략적 적합성에 관한 실증연구

김승범,이상천,장덕신,배성문 한국생산성학회 2004 生産性論集 Vol.18 No.3

This study tries to examine the strategic fit of competitive strategies and competitive priorities in domestic electronic firms' manufacturing strategy. The strategic fit is accepted as a major factor in explaining the difference of firms' productivity performances. To set up strategic fit model, the previous research on manufacturing strategy model has been examined thoroughly. Based on proposed model composed of competition environments, core competences(competitive advantage and value chain), competitive strategies and competitive priorities, stepwise multiple regression was used as exploratory method to find significant types of internal strategic fit. The test results show that core competences(especially competitive advantage) have more impacts on competitive strategy than competition environments. In addition, there exist the significant types of strategic fit between competitive strategies and priorities. That is, differentiation strategy takes delivery priority and focusing takes flexibility.