다소성 골괴사

서유성,박형근,최형석,김연일,이병일 순천향의학연구소 2002 Journal of Soonchunhyang Medical Science Vol.8 No.2

In case of the occurrence of osteonecrosis at three or more anatomical location, it is defined as multifocal osteonecrosis, but still any king of study with references hasn't been reported in Korea. The patient who had admitted due to the pain in both knee joints, both hip joints and left ankle joint and we diagnosed as multifocal osteonecrosis by using bone scan and magnetic resonance imaging. To relieve right knee joint and left hip joint pain, we perfomed arthroplasty. Here we present one case report of multifocal osteonecrosis through analysis by patient's history and hematologic examination and provide a review of the literature.

고관절 전 치환 성형술 후 탈구에 관한 치험 및 연구

서유성,김동진,박종석,임수재,나수균,최창욱 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

Dislocation is one of the serious complications in total hip replacement arthroplasties. The purpose of this study is to evaluate the risk factors of dislocation, including age, sex, preoperative diagnosis and bilaterality, history of previous hip surgery, positioning of component, soft tissue tension, treatment after dislocation or redislocation. Authors reviewed 190 patients of total hip replacement arthroplasty, which were performed from Jan. 1990 to Dec. 1996. 15 cases developed dislocation after surgery. Incidence of dislocation was 7.89%(15 of 190 cases). Dislocation after revision was not happened(0 of 18 cases). Inclination of acetabular cup was average 37.5° (range: 31° - 43° ). Average anteversion of the acetabular component was 18.1" by Woo and Morrey method, 11.4° by Hassan method. They were normal range except 3 cases. Dislocation was not prevented even though inclination and anteversion of acetabular cup were within normal range. Soft tissue tension is determined by change of limb and femoral neck length. Average limb length difference was -0.2mm(range; -l0mm - +10mm) and average offset difference was +1.7mm(range;-4mm - +18mm). Revision must be accomplished as soon as possible when limb shortening happen by upward migration of the acetabular component. In conclusion, anteversion of acetabular cup may be most important factor in our cases, so cup position must be fixed in proper position during operation.

Prediction of aggressiveness in early-stage hepatocellular carcinoma for selection of surgical treatment

Suk-Won Suh,Kwang-Woong Lee,Jeong-Moo Lee,Tae You,Youngrok Choi,Nam-Joon Yi,Kyung-Suk Suh 대한외과학회 2013 대한외과학회 학술대회 초록집 Vol.2013 No.5

Prediction of aggressiveness in early-stage hepatocellular carcinoma for selection of surgical treatment

Suk-Won Suh,Kwang-Woong Lee,Jeong-Moo Lee,Tae You,YoungRok Choi,Nam-Joon Yi,Kyung-Suk Suh 한국간담췌외과학회 2013 한국간담췌외과학회 학술대회지 Vol.2013 No.4

Session H : Nucleic Acid Biochemistry : CONFORMATIONAL TRANSITION OF 28S rRNA BY BINDING OF ANTISENSE DEOXYOLIGONUCLEOTIDE

You Suk Suh,Doo Sik Kim 생화학분자생물학회(구 한국생화학분자생물학회) 1993 추계학술대회집 Vol.- No.-

C.V.D. 방법에 의한 Cd_0.78Zn_0.22 S박막 성장과 광전기적 특성연구

유상하,이상렬,홍광준,서상석,김혜숙,전승룡,윤은희,문종대 조선대학교 기초과학연구소 1993 自然科學硏究 Vol.16 No.1

We had grown Cd_0.78Zn_0.22S polycrystal thin films on slide substrate using chemical vapour deposition(CVD) method. We measured X-ray diffraction patterns in order to study Cd_0.78Zn_0.22S polycrystal structure. We studied its band gap using transmission curves and photocurrent and also analyzed photoluminescence using configurational coordinate model. We measured Hall effect·on this sample by Van der Pauw method and studied on carrier density and mobility depending on temperature.

n-CdS_(0.46)Se_(0.54)/p-Cu_92-x)S_(0.46)Se_(0.54) 이종접합 태양전지의 제작과 그 특성에 관한 연구

유상하,최승평,이상열,홍광준,서상석,김혜숙,전승룡,윤은희,문종대,신영진,정태수,신현길,김택성,유기수 全北大學校 基礎科學硏究所 1994 基礎科學 Vol.16 No.-

승화방법에 의해 CdS_0.46Se_0.54 단결정을 성장하여 결정구조를 조사하고, Van der Pauw 방법으로 Hall effect를 측정하여 carrier density의 온도 의존성과 mobility의 온도 의존성을 조사하였다. 성장된 CdS_0.46Se_0.54 단결정을 치환반응하여 n-CdS_0.46Se_0.54/p-Cu_2-xS_0.46Se_0.54 이종접합 태양전지를 제작하였다. Spectral response, 전류-전압특성 및 전력변환 효율을 조사하여 그 결과로부터 개방전압은 0.48V, 단락 전류 밀도는 21mA/㎠, fill factor와 전력변환효율은 각각 0.75와 9.5%를 얻었다. CdS_0.46Se_0.54 single crystal was grown by a sublimation method. The crystal structure and the temperature dependence of carrier density and mobility of CdS_0.46Se_0.54 single crystal were studied. Heterojunction solar cells on n-CdS_0.46Se_0.54/p-Cu_2-xS_0.46Se_0.54 were fabricated by the substitution reaction. The spectral response, the J-U characteristics and the conversion efficiency of the n-CdS_0.46Se_0.54/p-Cu_2-xS_0.46Se_0.54 heterojunction solar cells were studied. The open-cricuit voltage, short-circuit density, fill factor and conversion efficiency of n-CdS_0.46Se_0.54/p-Cu_2-xS_0.46Se_0.54 heterojunction solar cells under 80mW/㎠ illumination were found to be 0.48V, 21mA/㎠, 0.75 and 9.5%, respectively.

Clinical and Radiologic Outcomes among Bipolar Hemiarthroplasty, Compression Hip Screw and Proximal Femur Nail Antirotation in Treating Comminuted Intertrochanteric Fractures

( You Sung Suh ),( Jae Hwi Nho ),( Seong Min Kim ),( Sijohn Hong ),( Hyung Suk Choi ),( Jong Seok Park ) 대한고관절학회 2015 Hip and Pelvis Vol.27 No.1

Purpose: In comminuted intertrochanteric fractures, various operative options have been introduced. The purpose of this study was to determine whether there were differences in clinical and radiologic outcomes among bipolar hemiarthroplasty (BH), compression hip screw (CHS) and proximal femur nail antirotation (PFNA) in treating comminuted intertrochanteric fractures (AO/OTA classification, A2 [22, 23]) Materials and Methods: We retrospectively evaluated total 150 patients (BH, 50; CHS, 50; PFNA, 50) who were operated due to intertrochanteric fractures from March 2010 to December 2012 and were older than 65 years at the time of surgery. We compared these three groups for radiologic and clinical outcomes at 12 months postoperatively, including Harris Hip Score, mobility (Koval stage), visual analogue scale and radiologic limb length discrepancy (shortening). Results: There was no statistical significance among three groups in clinical outcomes including Harris Hip Score, mobility (Koval stage), visual analogue scale. However, there was significant differences in radiologic limb discrepancy in plain radiographs at 12 months postoperatively (radiologic shortening: BH, 2.3 mm; CHS, 5.1 mm; PFNA, 3.0 mm; P=0.000). Conclusion: There were no clinical differences among BH, PFNA, and CHS in this study. However, notable limb length shortening could be originated during fracture healing in osteosynthesis, compared to arthroplasty (BH<PFNA<CHS).

출생직후 Capsaicin 투여가 제1차감각신경세포에 미치는 영향 : 조직계측학적 변화 및 유수축삭과 무수축삭의 분지율의 차이 Anatomical Changes and Disparity in Branching of Myelinated and Unmyelinated Axons

유병욱,서영석 고려대학교 의과대학 1985 고려대 의대 잡지 Vol.22 No.1

The present study is an analysis of dorsal root ganglion cells and their axons in both dorsal roots and peripheral nerves of L_(6) and S₁ segments in normal and capsaicin-pretreated adult rats. Capsaicin was injected subcutaneously on 2nd day of life. All rats were operated microsurgically to remove somatic and visceral motor nerve fibers from peripheral nerves, and fixed by transcardiac perfusion technique. The dorsal root ganglia were embedded in paraffin, cut serially, and all ganglion cells were counted by light microscopy. The dorsal roots and peripheral nerves were embedded in plastic mixture, and all myelinated and unmyelinated axons were counted by electron microscopy. The results obtained were summarized as followings. 1. In normal rats, the ganglion cell numbers were revealed wide individual differences in L_(6) and S₁ dorsal root ganglia, but not so wide, only less than 20%, when put together. 2. In capsaicin rats, the perished cells in dorsal root ganglia were 46% in average, and most of them were appeared to be small B cells. 3. In capsaicin rats, the decrease rates of axons in dorsal roots and peripheral nerves were almost same in L_(6) or S₁ segment, and the average decrease rate was 10% in myelinated axons, 58% in unmyelinated axons and 44% as a whole. 4. In normal rats, the branching rates were about same in doral root and periphera1 nerve in one segment, but not in different segments. The average rate (1.59) in L_(6) was lower than that (1.76) in S₁. 5. In capsaicin rats, the branching rates of preserved axons (1.67 in L_(6) and 1.87 in S₁) w x e higher than those in normal rats, and those of perished axons(1.49 in L_(6) and 1.63 in S₁) were lower than those in normal rats. 6. Thus, it is manifested that the neonatal capsaicin treatment causes the marked depletions of small B cells in dorsal root ganglia and of unmyelinated axons in dorsal roots and peripheral, i.e., the small ganglion cells give rise to the fine sensorry axons in dorsal roots and peripheral nerves. And, it is suggested that the branching rate of the fine unmyelinated axons is lower than that of large myelinated axons.

무수혈 환자에서 시행한 인공관절 치환술의 혈역학적 분석

서유성(You-Sung Suh),최형석(Hyung-Suk Choi),원성훈(Sung-Hun Won),김명회(Myoung-Hoe Kim),천동일(Dong-Il Chun),노재휘(Jae-Hwi Nho) 대한정형외과학회 2010 대한정형외과학회지 Vol.45 No.6

목적: 무수혈 환자군을 대상으로 인공관절 치환술 시행함에 있어 수혈 대체 요법을 적용하고 혈역학적 변화를 분석하여 그 결과를 알아보고자 하였다. 대상 및 방법 : 인공슬관절 치환술 및 인공고관절 치환술을 시행 받은 48명의 환자 57예를 대상으로 하였다. 수술 당시 평균 연령은 70.9세 였다. 총 57예 중 인공 슬관절 치환술 15예, 인공 고관절 치환술은 42예에서 시행하였다. 술 전 혈색소 수치가 10g/dL 이상인 경우 재조합 에리스로포에틴 2,000 단위를 일주일, 경구철분제 일주일을 투여하였고 혈색소 수치가 10g/dL 이하인 경우 재조합 에리스로포에틴 4000단위를 일주일, 경구철분제나 베노페롬을 일주일 투여하였다. 술 중에는 술 전 혈색소치에 상관없이 자가수혈, 혈장증량제, 국소지혈제를 사용하였으며, 술 후에는 재조합 에리스로포에틴 4,000 단위, 베노페롬을 일주일 투여하였다. 결과: 내원 시 평균 혈색소 수치가 10g/dl 이상인 환자군은 수술 후 7일째 평균 혈색소 수치가 10.7g/dl로 평균 1.85g/dl의 감소율을 보였고, 내원 시 평균 혈색소 수치가 10g/dl 이하인 환자군은 수술 후 7일째 평균 혈색소 수치가 9.18g/dl이었다. 인공 슬관절 치환술을 시행한 환자군은 내원 시 혈색소 수치가 12.8g/dl에서 수술 후 7일째 혈색소 수치가 10.96g/dl, 인공 고관절 치환술을 시행한 환자군은 내원시 혈색소 수치가 13.4g/dl에서 수술 후 7일째 혈색소 수치가 11.8g/dl, 재치환술을 시행한 환자군은 내원 시 혈색소 수치가 13.8g/dl에서 수술 후 7일째 혈색소 수치가 12.75g/dl였다. 결론: 무수혈 환자에서 정형외과적 인공관절 치환술시 적절한 수혈대체 요법의 정립이 필요하며 저자들은 적극적인 수혈 대체 요법의 적용을 통해 혈역학적 관점에서 좋은 결과를 얻었다. Purpose: To analyze the hemodynamic changes in patients who underwent total joint arthroplasty and received alternative treatment to blood transfusion. Materials and Methods: Fifty-seven cases in 48 patients who received total knee and hip arthroplasty between 1998 September and 2008 February were enrolled. The mean age at the point of surgery was 709 years. The types of joint arthroplasty included 15 cases of total knee arthroplsty and 42 cases of total hip arthroplasy. Alternatives to blood transfusion entailed administration of 2,000 units of recombinant EPO and oral iron supplement for 1 week in patients with preoperative hemoglobin level higher than 10 g/dl, and 4,000 units of recombinant EPO with oral iron supplement or venoferrum for 1 week in patients with preoperative hemoglobin level lower than 10 g/dl. Intra-operatively, autotransfusion, plasma expander, topical hemostatic agents were used irrespective of the preoperative hemoglobin level. Postoperatively, 4,000 unit of recombinant EPO and venoferrum were administered for one week. Results: Patients with mean hemoglobin level higher than 10 g/dl exhibited mean hemoglobin level of 10.7 g/dl (a mean 1.85 g/dl decrease) 7 days after the operation. Patients with mean hemoglobin level lower than 10 g/dl exhibited increased mean hemoglobin level of 9.18 g/dl (a mean 0.38 g/dl decrease) 7 days after the operation Patients who underwent total knee arthroplasty exhibited reduction of hemoglobin from 12.8 g/dl to 10.96 g/dl (a mean decrease of 14 g/dl) 7 days after the operation Patients who underwent total hip arthroplasty exhibited a change of hemoglobin from 13.4 g/dl to 11.8 g/dl (a mean decrease of 1.84 g/dl) 7 days after the operation. Patients who underwent revision arhtroplasty exhibited a change of hemoglobin from 13.8 g/dl to 12.75 g/dl (a mean decrease of 1.05 g/dl) 7days after the operation. Conclusion: In patients who refuse blood transfusion, there is a need to establish an adequate alternative blood management plan for surgery, such as total joint arthroplasty. We obtained good results with the hemodynamic protocol adapted for the perioperative period.