상대농도와 질량농도 측정법에 의한 기중 분진농도의 비교

정광호,성수원,안규동 가톨릭대학산업의학센타 산업의학연구소 1983 韓國의 産業醫學 Vol.22 No.1

This experiment was carried out to investigate the correlation of accuracy among five kinds of instruments which determined an airborne dust at the various locations of same type work. The results obtained were as follows; 1. Digital dust indicator-P type (DDI-P) instrument for determination of relative concentration was found not having significant variations when it was used without corrective coefficient to the quantitative concentration at the places with a few airborne dust in office and laboratory room. 2. Generally, there were the high correlations between determination values resulted by Digital dust indicator(DDI) and Piezobalance(PB). However, the correlation of two instruments to a filter weighing method was insignificant in the same type work. After determining several times (at least 5 times and over), it was desirable to fix the corrective-coefficient. 3. When the size of the particles of airborne dust was large or its concentration was high in suspended airborne dust, the determination values of High volume air sampler-Respirable(HVS(R)) were 2-4 times higher than that of Low volume air sampler-Respirable(LVS(R)). 4. The emyloyment of corrective coefficient for determination values of DDI and PB was not appropriate to HVS(R) comparing with LVS(R) because of the significant changeable differences. In addition, the determination instruments for relative concentration was not appropriate to using by itself at a manufactruing process. There were also problems about sampling time and evaluation when it was determined the total airborne dust with the open face type holder.

간 낭종을 동반한 성인 다낭신 환자에서 간 낭종의 감염 1예

정규성,서정철,주기산,김원식,임영국,정종훈,문철웅 朝鮮大學校 附設 醫學硏究所 1993 The Medical Journal of Chosun University Vol.18 No.1

Adult polycystic kidney disease(APKD) usually accompanies with renal and extrarenal manifestations and liver cysts are present in aproximately 30% of patients with APKD. Kidney cysts often accompany with hemorrhage, rupture, infection, however, liver cysts are usually asymptomatic and do not impair liver function. Rare complication of liver cysts in patient with APKD include portal hypertension with bleeding esophageal varices and hepatic failure with encephalopathy. But, in APKD patient, infection of liver cysts without infection of renal cysts is extremely rare. We report a case of infected liver cyst in a patient with APKD who has complained generalized abdominal pain and high fever which was confirmed by ultrasound and aspiration. The patient was treated successfully with repeated aspiration and systemic antibiotics.

Prednisolone 에 의한 장티푸스 抗菌治療의 지연

鄭喜泳,鄭圭源,金在亨,徐廷和,宋貞燮 대한감염학회 1976 감염 Vol.8 No.1

For the purpose of shortening of febrile period of typhoid fever, prednisolone was administered with bacteriocidal antibiotics though corticosteroid had not been used routinely for its possible side effects on typhoid fever. The authors suspected beneficial effects of corticosteroid because the action of bacteriocidal antibiotics was different from the action of bacteriostatic effects of chloramphenicol which was used in the last 30 years. The result was quite different from expectation and the febrile period of the patients was prolonged in all of the cases as shown in figures. Corticosteroid must not be used in typhoid fever so far as it is possible because delay of antibiotic effect than other known side effect. The possible mechanism of the longer intracellular parasitism of Salmonella typhi due to corticosteroid for the prolongation of fever was discussed.

새로운 축합시약을 이용한 아미드 합성법

鄭起源,蔡奎允,李英行 圓光大學校 1993 論文集 Vol.27 No.2

새로운 축합시약인 (3-nitropyridyl) dialkyl phosphate (3a,3b)를 2-hydroxy-3-nitropyridine (1), dialkyl chlorophosphate (2a,2b) 그리고 triethylamine을 dichloromethane 용액중에서 1시간동안 상온에서 반응시켜 쉽게 얻을 수 있었다. 축합시약인 3a와 3b는 온화한 반응 조건에서 아미드와 디펩티드를 합성하는데 있어서 유용한 시약임을 알 수 있었다. A new coupling reagents,(3-nitropyridyl) diallkyl phosphate (3a,3b), were readily prepared by the reaction of 2-hydroxy-3-nitropyridine (1), dialkyl chlorophosphate (2a,2b), and triethylamine in dichloromethane at room temperature for 1h. The coupling reagents, 3a and 3b, were found to be very useful for the preparation of amides and dipeptides under mild conditions.

고등학교 지구과학 실험·실습 요목 비교 분석

정원우,이윤종,기우항,김영호,양승영,강용희,안병호,임성규,윤일희,김중욱,윤성효,강동진 경북대학교 과학교육연구소 1997 科學敎育硏究誌 Vol.21 No.-

The purpose of this study is to investigate the status of the experimental and practical education in high school earth. The present status and reasonable management of the experimental and practical education in high school earth science have been grasped from the questionaires. To do this, eighty eight earth science teachers in Korea are administered questionaires. The frequency of the experimental and practical items in the seven kind of earth science text books were investigated. The problems and the reasonable management for experimental and practical education were proposed in this paper.

Interleukin-2가 Mouse간의 인산염분해효소의 활성에 미치는 영향

이규식,김원규,정호삼,강성섭 한양대학교 의과대학 1989 한양의대 학술지 Vol.9 No.1

In recent years, interleukin-2, a lymphokine produced by antigen or mitogenstimulated lymphocytes, has been intensively with the development of immunooncology and chemoimmunotherapy of the malignant tumor. Interleukin-2 mediates antitumor effect by stimulating the proliferation of helperand cytotoxic T cells, augmenting the cytolytic activities of cytotoxic T-lymphocytes and differentiating T-lymphocytes into a lymphokine-activated killer cell in vivo. Thus interleukin-2 induces the therapeutic effects on various sarcoma and carcinoma and regresses the pulmonary, hepatic and peritoneal metastases of various tumors. Although interleukin-2 is very effective for the treatment of various malignancy, it develops many side effects including fever, chill, malaise, mental confusion, diarrhea, vomiting and oliguria and causes pulmonary, hepatic and renal toxicities. Especially interleukin-2 results in increase of capillary permeability with weight gain, pulmonary edema, and ascites. In this experiment, the author studied the effect of interleukin-2 on the mouse liver, histochemically observing the changes in the activities of alkaline phosphatase, acid phosphatase and adenosine triphosphatase. Male mice, DDY strain, weighing 20gm, were used as experimental animals. The experimental animals were sacrificed at 3, 6, 12, 24 and 48 hours after intraperitoneal administration of two milions unit of interleukin-2 per kilogram of body weight. The specimens obtained from the liver were fixed in 10% neutral buffered formalin solution for 24 hours at 4℃ and sliced at 16㎛ thickness in a frozen cryostat. The activities of alkaline phosphatase and acid phosphatase were observed by the Gomori's method and the activity of adenosine triphosphatase was observed by the Wachstein and Meisel's method for histochemical study. The results obtained were as follows. 1. The acid phosphatase activity was strong positive at 12 hours and 24 hours groups in the central and portal zones of the liver lobules, but weak positive and moderate positive at 48 hours group in the central and portal zones of the liver lobules, respectively. 2. The alkaline phosphatase activity was weak positive at 6 hours and 12 hours groups and moderate positive at 48 hours group in the central and portal zone of the liver lobules. 3. The adenosine triphosphatase activity was trace positive in the central zone and weak positive in the portal zone of the liver lobules at 6 hours group but moderate positive at 48 hours group in the central and portal zones of the liver lobules. Consequently, it is suggested that interleukin-2 induce degenerative changes of the hepatocytes of the mouse, but it is recovered with time.

800m 달리기 後 血壓 및 心博數의 變化와 回復에 관한 硏究 : Concerning Overweight, Normal, and Underweight Students In a Girls' Middle School 女子中學校 肥滿, 正常, 低體重學生을 中心으로

원충희,曺圭勇 公州大學校스포츠科學硏究所 1999 스포츠科學硏究所論文集 Vol.- No.13

The purpose of this study is to observe the recovery of blood pressure and heartbeat rate of overweight, normal, and underweight students after they run 800m race and apply the results to class. To serve this aim, the blood pressure and the heartbeat rate in the normal situation without exercising, immediately, 5, 10, and 15 minutes after 800m race were comparatively analyzed. The subjects were 36 girl students from K-Middle School and they were taken out at random and measured both in the classroom and on the playground. For the athletic load quantity, the blood pressure and heartbeat rate were measured after 800m race without any special training. The data were statistically computerized in the method of SPSS/PC Program and the differences of blood pressure and heartbeat rate in the three groups were verified in the method of a one-way ANOVA. The results obtained from the analysis were as follows. 1. In normal situation, the blood pressure of the overweight students showed 119/71.08㎜Hg, the normal students 118.00/70.08㎜Hg, the underweight students 118.83/74.00㎜Hg, and the heartbeat rate of the overweight students showed 78.17/min., the normal students 79.17/min., the underweight students 77.25/min. As a result, the systolic blood pressure of the overweight students and the normal students were nearly the same, however the underweight students showed a bit lower. The heartbeat rates of three groups were almost the same. 2. Immediately after 800m race, the systolic blood pressure of the overweight students was the highest and that of the normal students was the lowest and there was a little difference between the overweight students and the other two groups, and the diastolic blood pressure was higher than that at resting in all the three groups. And the heartbeat rate showed almost twice the usual. 3. In 5 minutes after 800m race, the systolic blood pressure of the normal students recovered rapidly, the underweight students by 72.62% and the overweight students by 54.14%. The diastolic blood pressure of the underweight students dropped much, and the normality of the other two groups approached that of the resting time. The heartbeat rate of all the groups recovered nearly to that of the resting time. 4. In 10 minutes after 800m race, the systolic blood pressure of the underweight students became completely normal and the overweight students recovered by 67.31%, and the diastolic blood pressure of all the groups recovered normally, The heartbeat rate became normal in order of the underweight, normal, overweight student group. 5. In 15 minutes after 800m race, the systolic blood pressure of overweight students recovered by 81.32%, and the diastolic blood pressure of all the groups showed lower than that at resting. The change of the heartbeat rate became normal in order of the underweight, normal, overweight student group.

多重 處理를 利用한 工程 制御用 그래픽 콘솔 시스템의 設計

鄭南奎,張殷永,金元厚 한국항공대학교 1990 論文集 Vol.28 No.-

본 논문에서는 공정처리에 있어 시스템의 각종 기능 제어 및 감시에 사용되는 그래픽콘솔 시스템을 설계한다. 이때 UNIX 운영체제하에서 동적인 데이타의 입출력을 전담하는 프로세스를 두어 다른 기능을 수행하는 프로세스와 서로 동시에 수행할 수 있도록 다중처리 방식을 채틱함으로써, 공정상의 동적데이타가 손실되지 않도록 한다. 프로세스들은 각각 Configurator, Supervisor, I/O Interface로 구분하여 설계하며, 특히 I/O Interface를 모의동작시키는 Simulator를 두어, 구성된 그래픽 콘솔시스템을 모의 시험하므로써 경제적이고 범용성을 지니는 공정제어용 사용자 인터페이스임을 확인한다. In this thesis, a Graphic Console System is designed for monitoring and controlling the operation of process system. To prevent data loss, the Graphic Console System has multitasking structure under the UNIX-OS environment. The system consists of four major tasks;Configurator, Supervisor, I/O Interface, Simulator. We confirmed that the designed system is economical and universal interface state with the Simulator.

標識放鳥에 依한 韓國産 철새 集團의 季節的 分布와 그의 生態(Ⅰ)

元炳旿,禹漢貞,咸奎晃,田美子,尹茂夫 慶熙大學校 1967 論文集 Vol.5 No.-

實驗材料로 토기, 마우스 및 가물치를 使用하여서 致死至近量의 物理的 環境要因 (溫度, 重力, 電擊, 電離放射線 및 非電離放射線), 化學的 環境要因(無機이온) 및 生物學的 環境要因(媒質의 渗透壓)等에 依한 處理가 血液蛋白質의 電氣泳動像을 비롯하여 赤血球, 白血球, 헤마토크리트比, 血色素量, 赤血球脆弱性, 肝臟器官의 組織像 그리고 肝臟 및 腎臟器官重量等에 미치는 效果를 硏究調査하였다. 前記 致死至近量의 環境要因의 處理로 一般的으로 蛋白質代謝, 血液像, 肝臟器官의 組織像 및 肝臟器官重量等에 顯著한 變化를 招來함을 알 수 있었다. 總血淸蛋白質量의 顯著한 變化 및 알부민―굴로부린比의 變化等은 血液內의 渗透效果의 變化를 招來함을 示唆하여 준다. 血淸電氣泳動像의 變化는 前記 環境要因에 依한 處理로 因하여 蛋白質代謝의 異常 卽 肝臟機能의 異常을 招來함을 알 수 있다. 以上의 結果로 미루어 보아 致死至近量이 內的 및 外的의 物理的, 化學的및 生物學的 環境要因에 依한 處理로 因하여 血液蛋白質, 血液像 및 肝臟器官 等의 異常은 生體에 큰 損傷을 가져오며 아울러 生體의 生理的平衡에 有意性的인 變化를 招來한다고 思料된다. Seasonal distribution and ecology of migrant bird populations were studied by mist-netting and banding primarily in the ares of Kyunggido, Korea during 1963-1966. 1. From 6 June to 25 June 1963, 99 birds of 3 species and 3 July 1964 to 31 December 1966, a total of 123, 242 birds of 124 species were banded in Korea. 196 (144 Returns) recoveries of 22 species have been reported in Korea (outside of banding sites) and 7 recoveries of 5 species from abroad. 2. At Taenung, N.E. Seoul, Korea, 11623 birds of the Pied Wagtail and 9,013 birds of the House Swallow were banded in pear orchards. a. Both Wagtail and Swallow are summer resident Wagtail arrives Korea in the beginning of March and Swallows in early April and these gregarious species gather at night into large flocks to roost while juveniles maintain their post-breeding roosts in pear orchard from June to October until the time of Autumn migration. b. Both Wagtaill and Swallow maintain their roosts in the same site but they exhibit different roosting behavior. c. The time at which the Wagtails and Swallows arrive and leave the roost in relation to sunset varies with length of day, weather, however, light intensity mat remain the same. d. The Wagtail gathers around the feeding ground more than 20 kilometers from the roosting site. e. Some Wagtails and Swallows banded the previous year returned and roosted in the orchard. The fact that they repeatedly roost in the same areas suggest that after breeding some birds remain in the Orchard and some of them migrate southward. 3. During July 1964-October 1966, 78, 170 birds of 12 Emberiza species were banded primarily in Kyunggi-do. Emberiza rutila, Emberiza spodocephala, Emberiza tristrami and Emberiza aureola ornata are the dominant fall and spring migrants. In fall they prefer soy-bean, corn and especially millet fields while in spring they are mostly seen on wheat and barley fields. Emberiza rustica is the most abundant species during late fall and winter and they prefer open fields with bushes. Emberiza rutila migrates through Korea in May and from the beginning of August until the and of October. The sex ratio is 100 females to 155 males (11674 ♀, 17761 ♂). More males were caught than females each month except in September when more females were caught. Emberiza spodocephala migrates through Korea from the middle of April through the middle of May and from the meddle of September through October. Emberiza tristrami migrates southward through Korea the first half of May and during October. The sex ratio is 100 female to 140 males(392 ♀, 551 ♂). Emberiza aureola oruata megrates through Korea during May nd from early August until the end of October. Emberiza rustica migrates southward but some of them winter in Korea. The wintering period is from the early October until the end of April. The sex ratio is 100 females to 191 mules (13,450 ♀, 25,687 ♂). Emberiza yessoensis continentals migrates to Korea around the middle of October. Some of them wander in Korea while some of them migrate southward. The wandering period is from the middle of October to the meddle of February. Emberiza cioidos is a permanent resident and breeds in great number in Korea. However, they migrate southward in large flocks during winter and northward during spring. The sex ratio is 100 females to 159 males (497 ♀, 792 ♂). Emberiza e. elegans is a resident and breeds in fairly small number in Korea. but they migrate southward in large flocks around the end of October and northward around April. The sex ratio is 100 females to 280 males(462 ♀, 962 ♂). Emberiza f. fucata is a summer resident, arrives to Korea the middle of April and most of them migrate southward in September. Emberiza chrysophtys migrates southward through Korea in May and from September to October. Emberiza pusilla is a not uncommon transient during spring and autumn and some of it wanders during winter in Korea. Emberiza leucocephala leucocephala Known as a straggler based on the sex specimens but a rare winter visitor. It migrates southward through Korea and some of it wanders around the end of January to the middle of March. 4. Noteworthy records of 21 species observed by the authors and some new species in Korea are given, each with notes on banding and collection records-See text for each species. Observations were made on the feeding habits of nestlings of ten species, Lanius tigrinus, Butorides striatus amurensis, Fhnberiza f. fucata, Motazilla alba leucopsis, Oriolus chinensis diffusns. Accipiter nisus nisosimilis, Mierascelis amaurotis henssent. Garrulus glandarins brandtii, Accipiter solecnsis and Cyanopica eyamts Koreensis. The investigation was made in Kwangnung experimental forest, Kyunggido and the nearby open field by using collar method. Accipiter nisus nisosimiles, Microscelis amaurotis hensoni, Garrulus glandarius brandtii and Cyanopiea cyanus Koreenses are permanent residents and the other six species are common summer residents. The following is the food that these nestlings consumed. 1. Lanius tigrinus The food they consumed was animal matter Composes of; insect larvae-41.5%, insect adults-49.4%, spiders-7.69%, frogs-1.53%. The cicada, Gampsocleis ussuricnsis made up 33.8% of the insect larvae. The cricket, Platyplenra kacmpferi made up 35.4% of the adult insects. Only one species of spiders, Clubiona jucunda was seen, 7.69% of the food. 2. Butorides striatus amurensis The food was animal matters composed of; small freshwater fishes-18.57%, Ranidae-45.71%, others-5.71%. Twenty percent of the small freshwater fishes was Zacco platypus while Hemibarbus logirostris made up 14.28%. Among Amphibians, Rana n. nigromaculata included 22.8%. 3. Emberiza f. fucata The food was amimal matter; insect larvae-63.3%, adult insects-25.64%, others-12.78%, Since 48.1% of the food items was larvae of Pieris rapae, it is most useful for agriculture. 4. Motacilla alba larcopsis The food during their nestling period was animal matter compsed of; insect larvae-30.5%, adult insects-55.4%, spiders-13.9%. The commonest insect larvae were Odonata indet.-22.2%. The commonest adult insects were Syrphidae indet.-16.6%. Of the spiders Lyecsa sp. made up 12.1% and Lycosa astrigera-2.8%. 5. Oriolus chinensis diffusus The food was animal matter composed of; insect larvae-62.36%, adult insects-20.17%, others017.42%. It should be noted that from the initial time of its feeding until leaving it consumed Dendrolimus spectabilis, a noxious forest insect which made up 45.08% of the diet. Thus it is very useful birds eliminating noxious forest insects. 6. Accipiter nisus nisosimilis The food was animal matter composed of; small passerine birds-87.5%, Ranidac-12.05%. It consumed such forest birds as Paridae. 7. Microscelis amauretis hensani The food was primarily insect adults-79.65%, Mollusca-12.15%, vegetable matter-4.05%, insect larvae-2.70%. Araneina-1.35%. Homoptera was 43.35% of adult insects. 8. Garrulus glaudarins brandtii The food during its nestling pcriod was solely animal matter; insect larvae-38.80%, adult insects-28.90%, Araneina-24.87%, adult Amphibia-15.49%. Right afrer hatehing and until leaving its nest, Dendrolimus spectabilis-35.08%, Arancina-24.87%, Clubiona jueunda-6.43% were fed. Therefor 73.48% of the total food was noxious forestry insects. 9. Accipiter soloensis The food during the whole feeding period was primarily Rana n. nigroma-culata 89.09%, but small quantity of Platypleura Kaempferi 8.26%, was also fed. 10. Cyanopica cyanus koreensis The food was composed of; insect larvae-6.11%, adult insects-60.55%, Hyla arborea japonica 12.22%, vegetable matter-1.11%. Gampsocleis ussuriensis-23.39%, Platypleura knempferi-15.55%, and Hyla arborea japoniea-12.22% were the prefered food supplied during the whole feeding period.

Interleukin-2가 Mouse 자궁선상피세포의 미세구조에 미치는 영향

황규성,김원규,이규식,정호삼 한양대학교 의과대학 1990 한양의대 학술지 Vol.10 No.1

It is well known that the endometrium of uterus changes histologically during the estrous cycle in rodents. Interleukin-2, a kind of lymphokine produced by the T lymphocyte activated by antigen or mitogen, induces antitumor effect by stimulating the proliferation of helper and cytotoxic T lymphocytes, augmenting the cytolytic activities of the cytotoxic T lymphocyte and differentiating a precursor cell into a lymphokine-activated killer cel in vivo. Although interleukin-2 suppresses the metastasis of the malignant tumor into the adjacent organs and the tumor itself, it develops many side effects including fever, chills and decreased hepatic functions. Interleukin-2 also causes increase of capillary permeability with weight gain, pulmonary edema and ascites. In this experiment, the author studied the effect of interleukin-2 on the mouse uterine glandular cells, observing electron microscopically the changes in cytoplasmic organelles of uterine glandular epithelial cells in mice. Totals of 20 healthy female mice, DDY strain, weighing about 20 gm and exhibiting normal estrous cycle, were used as experimental animals were injected with 2 million units of interleukin-2 diluted in 0.2ml distilled water per kg of body weight and with 0.2ml of normal saline per kg of body weight in the control group for 5 days. And animals were sacrificed at 5th day after administration of interleukin-2. The specimens obtained from te corpus uteri were pre-fixed in 2% glutaradehyde-2.5% paraformaldehyde buffered in Millonig's phosphate solution (pH 7.2) and post-fixed in the 1% osmium tetroxide. After dehydration the specimens were embedded in Epon 812. Ultrathin sections, 600-800A in thickness, were made and double stained with uranyl acetate and lead citrate. And these preparations were observed with the electron microscope. The results obtained were as follows. 1. Microvilli were reduced and microfilaments in microvilli were degenerated. 2. The pronounced dilatation, sacculation and fragmentation of the cisternae of rough endoplasmic reticulum was associated with detachment of the membrane-bound ribosomes. 3. The formation of secondary lysosomes such as autophagic vacuoies and multivesicular bodies were observed. 4. Cristae of the some mitochondria were arranged irregularly and dissociated. Consequently, the results obtained in the present study suggest that interleukin-2 appears to be cytotoxic to the uterine glandular cells of the mouse and induces the degenerative changes of the uterine glandular cells.