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      • 특집 - 건축시공·공법·신소재 : 건식공법 조립식 단열판넬

        강성섭 대한건축학회 1990 建築 Vol.34 No.3

        동신특강(주)은 1982년에 우레탄 연속저압발포라인을 개설하고 1985년에는 증가하는 수요량의 해결 및 제품의 질적향상을 위하여 연속고압발포라인을 증설하여 현재 연간 200만m 의 생산능력을 지니고 있다. 본 원고에서 필자는 건식공법 자재조립식 단열파넬인 우레탄 통계 샌드위치 파넬을 생산, 시공 및 설계하는 기업으로서의 당사의 소개와 함께 단열파넬의 선두주자라는 자부심으로 당사의 공볍 자재 및 신소재에 대하여 가능한한 객관적 설명으로 건식공법 자재 조립식 단열파넬에 대한 현위상을 파악하는데 건축관련업계 및 건축인에게 작으나마 보탬이 됐으면 하는 바람이다.

      • Interleukin-2가 Mouse간의 인산염분해효소의 활성에 미치는 영향

        이규식,김원규,정호삼,강성섭 한양대학교 의과대학 1989 한양의대 학술지 Vol.9 No.1

        In recent years, interleukin-2, a lymphokine produced by antigen or mitogenstimulated lymphocytes, has been intensively with the development of immunooncology and chemoimmunotherapy of the malignant tumor. Interleukin-2 mediates antitumor effect by stimulating the proliferation of helperand cytotoxic T cells, augmenting the cytolytic activities of cytotoxic T-lymphocytes and differentiating T-lymphocytes into a lymphokine-activated killer cell in vivo. Thus interleukin-2 induces the therapeutic effects on various sarcoma and carcinoma and regresses the pulmonary, hepatic and peritoneal metastases of various tumors. Although interleukin-2 is very effective for the treatment of various malignancy, it develops many side effects including fever, chill, malaise, mental confusion, diarrhea, vomiting and oliguria and causes pulmonary, hepatic and renal toxicities. Especially interleukin-2 results in increase of capillary permeability with weight gain, pulmonary edema, and ascites. In this experiment, the author studied the effect of interleukin-2 on the mouse liver, histochemically observing the changes in the activities of alkaline phosphatase, acid phosphatase and adenosine triphosphatase. Male mice, DDY strain, weighing 20gm, were used as experimental animals. The experimental animals were sacrificed at 3, 6, 12, 24 and 48 hours after intraperitoneal administration of two milions unit of interleukin-2 per kilogram of body weight. The specimens obtained from the liver were fixed in 10% neutral buffered formalin solution for 24 hours at 4℃ and sliced at 16㎛ thickness in a frozen cryostat. The activities of alkaline phosphatase and acid phosphatase were observed by the Gomori's method and the activity of adenosine triphosphatase was observed by the Wachstein and Meisel's method for histochemical study. The results obtained were as follows. 1. The acid phosphatase activity was strong positive at 12 hours and 24 hours groups in the central and portal zones of the liver lobules, but weak positive and moderate positive at 48 hours group in the central and portal zones of the liver lobules, respectively. 2. The alkaline phosphatase activity was weak positive at 6 hours and 12 hours groups and moderate positive at 48 hours group in the central and portal zone of the liver lobules. 3. The adenosine triphosphatase activity was trace positive in the central zone and weak positive in the portal zone of the liver lobules at 6 hours group but moderate positive at 48 hours group in the central and portal zones of the liver lobules. Consequently, it is suggested that interleukin-2 induce degenerative changes of the hepatocytes of the mouse, but it is recovered with time.

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      • 過法 10年間 本 李鼻咽喉科에서 시행한 組織生檢 553例에 관한 統計的 考察

        咸泰英,趙賢熙,李鮮亨,강성섭,盧永洙,田丙勳 인제대학교 1982 仁濟醫學 Vol.3 No.3

        仁製醫科大學부속 서울 白病院 개원 이래 1981年 6月까지 約 10年間 耳鼻咽喉科에서 施行한 生檢에 대한 統計的 분석을 文獻的 考察과 아울러 보고함. A statistical analysis of 553 cases of diagnostic biopsy which were performed at our clinic during past 10 years was carried out. Following resells were obtained; 1) Among 33503 new out-patients during past 10 years, 553 cases of biopsy were performed. Male was 367 cases(66.4%) and female was 186 cases(33.6%). 2) Histopathological findings were reported as non-specific inflammation in 139 cases(25.1%), non-neoplastic benign tumor in 161 cases(29.1%), malignant tumor in 124 eases(22.4%), true benign tumor in 90 cases(16.3%), specific inflammation in 10cases(1.8%) and rebiopsy was requested in 29 cases(5.2%). 3) Malignant tumor was revealed more frequently in older patients over 5th decade, but benign tumor was found relatively in younger group. 4) The male to female ratio was 3 : 2 far true benign tumor and 4 : 1 for malignant tumor. 5) The most common location of true benign tumor was the oral cavity(43.3%), and then the larynx(35.5%), the nose and paranasal sinus(11.1%), the pharynx(3.3%) in order. In malignant tumor, the most common location was the oral cavity with the incidence of 33.1% and the larynx(31.5%), nose and paranasal sinus(23.4%), the pharynx(10.5%) in order. 6) The most frequent histopathological type of true benign tumor was papilloma with the incidence of 62.6% and then mixed tumor(14.4%), hemangioma(7.7%), fibroma(5.5%) in order. A case of soft palate myxoma in our series was one of the rarest forms of benign tumor. 7) The most common histopathological type of malignant tumor was squamous cell carcinoma with the incidence of 66.1% and then malignant lymphoma(8.9%), adenocarcinoma(4.0%), lymphoepithelioma(2.4%) in order and two cases of chondrosarcoma in PNS were found.

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