Characteristics of Korean ginseng varieties of Gumpoong, Sunun, Sunpoong, Sunone, Cheongsun, and Sunhyang

Jang-Ho Lee,Joon-Soo Lee,Woo-Saeng Kwon,Je-Yong Kang,Dong-Yun Lee,Jun-Gyo In,Yun-Soo Kim,Jiho Seo,In-Ho Baeg,Il-Moo Chang,Keith Grainger 고려인삼학회 2015 Journal of Ginseng Research Vol.39 No.2

Background: Ginseng (Panax ginseng Meyer) is an important medicinal herbs in Asia. However, ginsengvarieties are less developed. Method: To developed ginseng varieties, a pure line selection method was applied in this study. Results: Gumpoong was testing of 4-yr-old specimens in 2002, the proportions of the below-groundroots that were rusty colored for Gumpoong was 1.29 in Daejeon and 1.45 in Eumseong, whereas theproportions for its yellow berry variant were 2.60 and 2.45 in the two regions, respectively. Thus theGumpoong was resistant to root rust. Sunpoong has a high yielding property. Its average root weight is70.6 g for 6-yr-old roots. Its yield is 2.9 kg/1.62m2 and the rate of heaven- and earth-grade product is20.9%, which is very high compared to 9.4% for Yunpoong. Sunone is resistance to root rot and thesurvival rate of 4-yr-old roots was 44.4% in 1997, whereas that of the violet-stem variant landrace was21.7%. Sunhyang has content of arginyl-fructosyl-glucose (AFG), which produces the unique scent of redginseng, is 95.1 mmol/g and greater than the 30.8 mmol/g of Chunpoong in 6-yr-old plants. Sunun andCheongsun are being nurtured to protect genetic resources. Conclusion: Developed ginsneg varieties will be used as the basis for the protection of genetic resourcesand breeding. Jang-Ho Lee

작업관련성 수근관증후근 감시체계

정우철,권호장,하미나,노상철,권범선,현정근,이성재,이종민,권정이,김준성,백남종,이호,이경우,이삼규 大韓産業醫學會 2004 대한직업환경의학회지 Vol.16 No.1

목적: 작업관련 근골격계질환은 중요한 직업관련성 질환 중의 하나이고 작업관련 수근관증후군은 이러한 작업관련 근골격계질환 중에서도 많은 부분을 차지한다. 이 연구는 작업관련 수근관증후군의 역학적 특성에 대해 알아보고자 수행되었다. 방법: 본 연구에서는 '수근관증후군 감시체계'를 통해 2000년 6월부터 2003년 2월까지 보고 된 672례의 수근관증후군 사례를 분석하였다. 직업력이 확인된 314명을 대상으로는 직업 및 작업내용에 따라 작업관련성 수근관증후군의 비율이 어떻게 달라지는지를 분석함으로써 수근관증후군 위험요인을 조사하였다. 결과: 직업력이 확인된 314명의 환자 중 작업 관련성이 의심되는 사람은 228명 (72.6%) 이었다. 직업별로는 '단순노무종사자', '농림어업숙련자', '서비스종사자' 등에서 작업관련 수근관증후군의 비율이 여성에서 유의하게 높게 나타났으나 연령, 비만도 지수, 과거병력 등에 따른 차이는 관찰되지 않았다. 주관적 증상 중에 '손을 많이 사용한 후 심해진다'와 '손을 털면 덜해진다'라는 항목을 작업관련성 수근관증후군 환자에서 더 많이 호소하였고 다른 증상은 별다른 차이를 보이지 않았다. 작업관련성 수근관증후군 환자가 비교적 많이 노출되는 작업은 '지나치게 손을 뻗쳐서 하는 일', '손을 불편한자세로 유지하는 일' 등이었다. 결론: 전체 수근관증후군 중 작업관련성이 있다는 비율이 매우 높은 것을 확인할 수 있었다. 수근관증후군 감시체계가 작업관련성 수근관증후군의 여러 특성을 밝히는데 매우 효과적인 것으로 나타났으나 현재까지는 중재 대상을 구체적으로 특정하기에는 한계가 있다. Objectives: Carpal tunnel syndrome (CTS) is one of the most important work related musculo-skeletal diseases in Korea. However, there are few epidemiologic studies on the work-related CTS (WR-CTS). This study aimed to investigate the epidemiologic characteristics of WR-CTS in Korea. Methods: Data obtained from the "CTS Surveillance System". Physician case-reports in the surveillance were used to document patterns of WR-CTS by age, gender, occupation, sign, symptom, working history. Results: Six hundred and seventy-two cases of WR-CTS were ascertained of which 3 14 with complete information on occupational history were analyzed. It has been estimated that as many as 72% of' all CTS cases are work-related. The highest proportion of WR-CTS was observed in 'elementary occupation workers', followed by 'skilled agricultural, forestry and fishery worker'. The distributions of WR-CTS cases were similar with respect to age, obesity, and past medical history. The proportion of WR-CTS was higher in females. There was no significant difference in physical examination findings between WR-CTS and non WR-CTS cases. Repetitive work and the inappropriate hand posture seemed to be the risks for WR-CTS. Conclusion: WR-CTS is a significant public health problem. The CTS surveillance system is quite useful to elucidate the characteristics of WR-CTS, but it remains of limited use in targeting specific industries and occupations for intervention.

제조업 근로자들의 혈청 Perfluorooctanoic Acid (PFOA) 농도와 생활습관 및 직업적 관련요인

장상환,이채관,김대환,김권복,안진홍,김휘동,이창희,김정호,이종태 大韓産業醫學會 2008 대한직업환경의학회지 Vol.20 No.3

목적: PFOA에 노출이 가능한 제조업 근로자들을 대상으로 혈청 PFOA농도를 조사하고 생활습관, 직업적 요인, 간기능 및 혈청 지질과의 관련성을 연구하고자 하였다. 방법: 2007년 8월부터 12월까지 부산지역 1개 대학병원 산업의학과에서 건강진단을 받은 PFOA노출 가능성이 있는 제조업 사업장 근로자 남자 203명과 여자112명의 총315명을 대상으로 하였다. 생활습관 및 직업적 요인을 설문조사 하였고, 혈청 PFOA 농도를 LC-MS/MS로 분석하였으며, 간기능 및 혈청 지질 검사를 실시하였다. 결과: 혈청 PFOA 농도의 평균은 전체가 8.0 ng/mL이었으며, 남자가 9.0 ng/mL, 여자가 6.3 ng/mL로 남자가 여자보다 통계적으로 유의하게 높았다(p<0.001). 다중회귀분석을 시행한 결과 성, 연령, 체질량지수, 총 콜레스테롤 등이 유의하게 나타났으며, 성별로는 남성에서, 연령이 많을 수록, 총 콜레스테롤이 높을 수록, 체질량지수가 낮을 수록 혈청 PFOA의 농도가 통계적으로 유의하게 높았다. 로지스틱 회귀분석을 실시하여 성과 연령을 보정한 교차비를 산출한 결과, 섬유제품 염색, 정리 및 마무리 가공업(OR 6.16)이 통계적으로 유의하게 높았고, 주형 및 금형 제조업(OR 4.84), 선박 구성부분품 제조업 (OR 3.87), 플라스틱 합성피혁 제조업 (OR 10.05) 등이 상대적으로 높았다. 결론: 제조업 근로자들의 혈청 PFOA 농도는 성, 연령 및 총 콜레스테를 등과 관련성이 있었고, 업종별로는 섬유제품 염색, 정리 및 마무리 가공업에서 높은 것으로 조사되었다. 이러한 결과는 PFOA의 인체 위해성을 조사하기 위한 기초자료로 활용가치가 있을 것이다. Objectives: The objective of this study was to determine serum perfluorooctanoic acid (PFOA) concentrations and to investigate the relationship of lifestyle, health status and work-related factors among workers at manufacturing companies with possible occupational exposure to PFOA. Methods: The study subjects were 315 workers (male 203, female 112) of manufacturing companies with possible exposure to PFOA from August to December, 2007. A questionnaire was administered to investigate lifestyle and work-related factors. Serum PFOA concentrations were analyzed by LC-MS/MS, and liver function and total cholesterol were also tested. Results: Serum PFOA concentrations ranged from 1.0 to 40.9 ng/mL (mean 8.0 ng/mL). Serum PFOA concentrations increased with age. Male workers had higher PFOA concentration than female workers (male 9.0 ng/mL; female 6.3 ng/mL). According to stepwise multiple regression analysis, factors significantly associated with PFOA concentration were male, being older, higher total cholesterol, and lower body mass index. Adjusted for age and gender by logistic regression, dyeing and finishing textiles had significantly higher odds ratio (OR) of 6.16, and moulding patterns, moulds and industrial patterns (OR=4.84), sections for ships (OR=3.87), and plastics synthetic leather (OR=1O.05) had marginally significantly high odds ratios. Conclusions: This study demonstrated the factors affecting serum PFOA concentration of workers at manufacturing companies. Further study is needed to ensure the effect of occupational exposure on serum PFOA concentration.

소아 조갑진균증에서 Itraconazole 주기요법의 치료효과

권경술,이재봉,진현우,오창근,장호선,임재영 대한의진균학회 2003 대한의진균학회지 Vol.8 No.4

황사의 건강영향

권호장,조수헌 대한의사협회 2004 대한의사협회지 Vol.47 No.5

VDT 작업자의 작업관련성 근골격계장애 : 일반 대조군과의 비교연구 Comparison with control groups

권호장,김돈규 단국대학교 1998 論文集 Vol.33 No.-

A cross-sectional study was conducted to assess the prevalence of the work-related musculoskeletal disorders(WRMSD) among employees using video display terminals. The study included 113 female telecommunication employees from three companies and control groups of housewives and office ladies. Information on demographics, individual factors were obtained by self-administered questionnaire. Cases of WRMSD were defined as one or more symptoms(e.g. pain, aching, stiffness, burning, numbness, or tingling) in one of the four upper extremity joint area(nect, shoulder, elbow, hand/wrist) which lasted more than 1 weeks or occurred at least once a month within the past year. Shoulder symptoms(71.7%) were the most frequently reported during the current week, followed by neck(68.1%), hand and wrist(60.2), and elbow symptoms(31.9%) in VDT operators. But in housewives and office ladies, the symptom prevalence was much lower than VDT operators for each location. Neck symptoms were correlated with the level of education and shoulder symptoms were correlated with the location of office. This results suggest of high prevalence of musculoskeletal disorders of the upper extremities among VDT workers.

인슐린 비의존형 당뇨병 환자에서 당뇨병성 신증의 지표로서 혈청과 요Ⅳ형 collagen의 의의

장태종,최병진,반금진,노영호,김소연,조민구,이권전,김윤권 대한신장학회 1996 대한신장학회잡지 Vol.15 No.4

신경행동학적 증상 설문지의 타당도 및 신뢰도에 관한 연구

권호장,조수헌,임현술 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.1

유기용제 폭로에 의한 신경행동학적 장애를 선별 검사 할 수 있도록 고안된 설문지의 타당도와 신뢰도를 검정할 목적으로 유기용제를 사용하는 페인트 제조공장과 유기용제를 전혀 사용하지 않는 코일제조 공장의 근로자를 대상으로 2차에 걸쳐 설문조사를 실시하여 다음과 같은 결과를 얻었다. 1. 유기용제 폭로 근로자들이 비폭로 근로자들에 비해 증상총점의 평균이 통계적으로 유의하게 높았으며 이 결과는 나이, 근무기간, 교육연한, 음주, 흡연 등의 교란 요인을 통제하고도 유지되었다. 2. 신뢰도를 보기 위하여 페인트제조공장 근로자를 대상으로 2개월 간격으로 시행한 검사-재검사에서 문항별 kappa값은 0.15-0.69의 범위안에 있었으며 0,4이상으로 비교적 일치도가 높은 문항은 31문항 중 16문항이었다. 3. 검사문항간에 내적 일치도를 보기 위하여 Cronbach Alpha계수를 구한 결과 분포를 표준화하기 이전에는 0.85, 분포를 표준화한 이후에는 0.86의 값을 보였다. 이상의 결과를 볼 때 본 연구에 사용된 설문지는 유기용제 폭로로 인한 신경행동학적 장애를 비교적 잘 반영하고 있으며 신뢰도도 비교적 높은 것으로 판단되었다. There are many studies on the neurobehavioral symptoms due to organic solvent exposure using questionnaire. However there is little published evidence on validity and reliability of the questionnaire on the neurobehavioral symptoms. In present study, the authors tested the validity and reliability of our questionnaire, which was designed for screening neurobehavioral disturbance in organic solvent exposer. Questionnaire was administered to the workers of one paint manufacturing plant and one coil manufacturing plant. In order to evaluate validity of the questionnaire, the average questionnaire scores of two plants were compared. The average score of paint manufacturing plant were higher than that of coil manufacturing plant and the difference was statistically significant. After adjustment of age, duration of employment, education, smoking history and alcohol consumption, significance was maintained. Test-retest reliability was evaluated by kappa statistics. More than 50% of question items showed values of kappa above 0.4. Cronbach coefficient alpha which reflects internal consistency of the questionnaire was 0.86. Overall the data showed that validity and reliability of the questionnaire were generally acceptable.

수용성 키틴이 백서 창상치유에 미치는 영향

강장석,조용남,정상훈,유 결,임진수,권 호,조용우,고석원 大韓成形外科學會 2001 Archives of Plastic Surgery Vol.28 No.1

VDT 업무가 근골격계장애에 미치는 영향

권호장,하미나,김돈규,백남종,조수헌,한태륜 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.4

As use of the visual display terminal(VDT) is becoming more generalized as a result of office automation, the so-called 'VDT syndrome' which is often observed with the workers using VDT has emerged as a serious occupational health problem. However, few comparative study with control group using not only subjective symptom but also physical examination has been conducted. We have conducted a study comparing prevalence rated of musculoskeletal disorder between 113 VDT operators of a telecommunication company and the control groups of housewives and office ladies through a review of subjective symptoms as well as physical examination by physiatrist to understand the magnitude of problem and relative risk of VDT worker. The symptom rates of upper extremity disability in VDT operators were higher than those of controls especially in neck and shoulder area. Fifty-four(47.8%) of 113 VDT operators met our case definition of upper extremity disorder by subjective symptom and physical examination. Myofascial pain syndrome of neck and shoulder muscles were the most common(46.9%). The odd ratio of using VDT operation for developing myofascial pain syndrome in the neck or shoulder area were 2.52(compared to controls of office ladies) and 2.64(compared to controls of housewives). Other anatomical lesion such as elbow, hand and wrist shows slight higher prevalence rates of musculoskeletal disorder than control groups but not statistically significant.