VP-16으로 성공적으로 치료된 위 Kaposi 육종 1예

양웅석,송근암,조몽,이재승,송철수,김형욱,김영민,이수봉,김태오,이성훈 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.4

The skin is an uncommon site of distant metastasis from any internal malignancy, and the incidence of metastatic skin lesions as the first symptom of disease is only 0.8% in patients with all systemic malignancies. Furthermore, cutaneous metastasis from adenocarcinoma of the stomach has been found to be extremely rare. A 35-year-old female patient was admitted due to multiple cutaneous nodules in her chest, abdomen, and back. A gastroendoscopic examination and biopsy was made according to the results of skin pathologic findings. Stomach and skin biopsy results revealed a signet ring cell type of adenocarcinoma. A case of gastric adenocarcinoma in which metastatic skin nodules appeared as the first sign of disease, is here in reported with a review of related literature.

A comparison of survival outcome of open, total laparoscopic and laparoscopy-assisted vaginal radical hysterectomy in patients with early cervical cancer of stage IB2

( Sul Lee ),( Hyung Joon Yoon ),( Eun Hye Jeon ),( Juseok Yang ),( Yong Jung Song ),( Hyun Jin Roh ),( Sang Hun Lee ),( Byung Su Kwon ),( Ki Hyung Kim ),( Dong Soo Suh ) 대한산부인과학회 2019 대한산부인과학회 학술대회 Vol.105 No.-

Objective: The aim of this study is to evaluate oncologic outcomes of total abdominal radical hysterectomy (TARH), total laparoscopic radical hysterectomy (TLRH) and laparoscopic-assisted radical vaginal hysterectomy (LARVH) in early cervical cancer patients (stage IB2-3, tumor size≥2cm), analyzing the risk factors that may affect the clinical results. Methods: A total of 756 patients underwent radical hysterectomy between 2000 and 2019 from three university hospitals (Pusan National University Hospital, Yang-san Pusan National University Hospital, Ulsan University Hospital) were enrolled. Among them, 172 patients with stage IB2-3 were analyzed retrospectively. Results: Seventy-seven patients were treated with TARH, and 95 were managed via minimally invasive surgery (MIS), consisting of 35 with TLRH and 60 with LARVH. TARH group had better disease five-year disease free survival (DFS) and overall survival (OS) compared with MIS group (86.4% vs. 73.4 for DFS and 91.7 vs. 82.2 for OS), but not statistically significant in both (p=0.058 for DFS and p=0.119 for OS). When TARH and the LARVH group were compared, both five-year DFS and OS were not significant different (86.4 vs 82.2%; p=0.288 for DFS and 91.7 vs 84.4%; p=0.206 for OS). However, when TARH and the TLRH group were compared, TLRH group had significantly worse five-year DFS than TARH (86.4 vs 54.5%; p=0.008), but five-year OS was not significant different (91.7 vs 77.5%; p=0.127). Multivariate analysis showed that LN metastasis and TLRH surgical approaches were an independent prognostic factor for DFS in IB2-3 cervical cancers. Conclusion: Our findings provided the evidence that TLRH surgical approach was associated with worse DFS in IB2-3 cervical cancers but that of LARVH was not. Such results may have important implications of colpotomy method for MIS in cervical cancer.

Bortezomib과 Dexamthasone으로 치료한 골수외 형질세포종 4예

백종현,이은영,장리라,손창배,신은경,서정아,이지숙,이호섭,이상민,신성훈,김양수 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

Despite the use of aggressive local and systemic treatment including autologous stem cell transplantation in multiple myeloma, extramedullary recurrences are common and the prognosis of these patients is poor. Many novel drugs such as thalidomide, lenalidomide and bortezomib improve the response of treatment of multiple myeloma, but some reports failed to describe thalidomide has effect in extramedullary plasmacytoma. Recent data report on the successful treatment plasmacytomas with bortezomib in patients with advanced multiple myeloma. We treated 4 relapsed or refractory extramedullary plasmacytomas with bortezomib at our institution. We recognized all these extramedullary plasmacytomas decreased and showed more than partial response. This report lends support to the efficacy of bortezomib in the treatment of plasmacytoma and describes the safe use of bortezomib. Responses may, however, be of short duration. Therefore, despite our limited experience, we propose that bortezomib may be considered a therapeutic option for such patients who have risk of radiation therapy

의과대학생의 자연최면경험과 최면유도점수의 상관관계

이정태,최윤정,전양환,성양숙,박원명,김광수,유태열 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.5

목 적 : 저자들은 자연최면경험과 최면감수성간의 관계를 알아보기 위하여 자연최면점수와 최면유도 척도로 얻은 최면유도점수 및 유도점수와의 관계를 알아보고, MBTI(Myers-Briggs Type Inventory)의 성격유형과 이들의 상호관련성을 알아보려고 하였다. 방 법 : 가톨릭대학교 의과대학에 재학중인 63명의 의대생들을 대상으로 하여 자연최면경험에 대한 설문지와 MBTI를 작성하게 하고 최면유도척도로 최면을 유도하면서 최면유도점수와 유도점수를 얻었다. 결 과 : 1) 자연최면점수와 유도점수 사이에서 양의 상관관계가 있었고, 최면유도점수와 유도점수 사이에도 양의 상관관계가 있었다. 2) 자연최면점수와 최면유도점수 사이에서는 통계적으로 유의한 상관관계가 없었다. 3) MBTI의 각 성격유형들은 최면유도점수와 유도점수 사이에서 양의 상관관계가 있는 것으로 나타났다. 4) 외향형과 사고형의 성격유형은 자연최면점수와 최면유도점수에서 각각 양의 상관관계가 있었고, 자연최면점수와 유도점수 사이에서도 양의 상관관계가 있었다. 5) 직관형과 판단형은 자연최면점수와 유도점수 사이에서 각각 양의 상관관계를 보였다. 결 론 : 자연최면점수는 유도점수와 상관관계가 있었다. MBTI의 외향형과 사고형에서는 자연최면경험이 많을수록 최면유도가 잘 된다는 것을 시사하였다. Objective : We attempted to investigate the relation between naturally occurring hypnotic experiences and hypnotizability. We examined the correlations among hypnotic induction profile scores, natural hypnotic scores, induction scores and MBTI personality types. Methods : Sixty-three medical students completed NHQ(natural hypnotic questionnaire) developed from a list of naturally occuring hypnotic-like experiences and MBTI(Myers-Briggs Type Inventory). HIP(Hypnotic Induction Profile) was also administered to all the subjects. HIP score and IND(induction score) were obtained. Results : 1) The NHS(natural hypnotic score) was significantly correlated with IND in all the subjects. The IND also showed significant correlation with HIP score. 2) There was no significant correlation between NHS and HIP scores. 3) HIP scores were positively correlated with induction scores in all types of MBTI. 4) Natural hypnotic scores were positively correlated with HIP scores and induction scores in introvert and thinking types. 5) There were positive correlations between natural hypnotic scores and induction scores in intuition and judgment types. Conclusion : The natural hypnotic scores were correlated with induction scores. It is suggested that the more the naturally-occurring hypnotic experience is experienced, the better the hypnotic induction is induced in introvert and thinking types of MBTI personality types.

제방안전에 미치는 식생의 영향에 관한 이론적 검토

양수룡,이춘석 진주산업대학교 건설기술연구소 1998 건설기술연구소보 Vol.1 No.-

하도내에는 많은 종류의 식생이 분포하며, 이들의 기능은 지금까지 대단히 부정적인 요소로 판단되었다. 즉 홍수시 홍수단면의 감소뿐 아니라 국부세굴에 의한 제방붕괴 등을 유발하는 것으로 알려져 있다. 반면 최근의 경향은 하천내의 식생이 하천이라는 자연생태계를 보호하고, 친수공간을 제공하며 나아가 하천제방의 안정에도 상당한 도움을 주는 것으로 알려져 있다. 이는 하천제방에 위치한 나무의 경우 단단한 뿌리조직의 발달로 인하여 홍수시 소류력에 대한 저항력을 증가시키며, 제방사면의 밀도를 증가시키기 때문인 것으로 밝혀져 있다. There are many kind of trees and grasses in natural stream. Vegetation(trees) is negative effects on prevention flood and structure - bank, bridge. Vegetation in stream channel reduces the cross-section and hydraulic conductivity of channel and the flow velocity is enlarged and local scouring by tree is occured and destroyed the bank. or other structure in stream. But in recently research, the effect of tree is more positive. The tree near the channel provides shadow in water and prohibites the rising water temperature and provides more comfortable habitat to fish and the tree on the bank makes the soil density high and provides the resistance to scouring.

불평형을 고려한 절삭력 모델에 관한 연구

양완석,이수훈 한국공작기계학회 2001 한국생산제조학회지 Vol.10 No.1

This paper is on a new cutting force model which includes the force caused by unbalance. The cutting forces under the different additional masses are measured with the spindle speed changed. The model is justified through correlation between simulation and experimental result.

우묵사스레피(Eurya emarginata)의 플라보노이드 화합물의 분리 및 동정

양홍철,박수영,강희경,이남호 제주대학교 생명과학연구소 2001 제주생명과학연구 Vol.4 No.-

The extracts of Eurya emarginata showed inhibitory effect on the growth of HL-60 leukemia cells. So, 80% methanol(MeOH) extract of its leaves was partitioned to hexane, ethyl acetate, n-butanol and residual water fractions. The ethyl acetate fraction, which showed desirable activities, was further purified using SiO2 column chromatography(CC) followed by reverse phase silica gel CC, then another normal CC to give fraction 4-1-8 as a pure compound. The compound 4-1-8 was analyzed by NMR spectrometry using 1H, 13C, DEPT, HMQC and HMBC spectra, and finally proved to be well-known flavono glycoside, Quercitrin.

豚內 副産物의 特性과 加工利用에 關한 硏究 : Ⅱ. 加熱處理가 物理的 性質과 嗜好에 미치는 영향

양철영,이상건,윤정의,허윤행,채수규,노완섭 서울保健大學 1989 論文集 Vol.9 No.1

자연적 재현을 위한 가변 닻점을 이용한 색역 사상

이채수,박양우 경운대학교 산업기술연구소 2000 産業技術硏究論文誌 Vol.3 No.1(B)

In this paper, new gamut-mapping algorithm (GMA) that utilizes variable anchor points (center of gravity on the luminance axis) is proposed. The proposed algorithm increases luminance range, which is reduced from conventional gamut mapping toward an anchor point. In this process, this algorithm utilizes multiple anchor point with constant slopes to both reduce a sudden color change on the gamut boundary of the printer and to maintain a uniform color change during the mapping process. Accordingly, the proposed algorithm can reproduce high quality images with low-cost color devices.

여성 요실금에서 Kontinence™와 Compact Elite™의 치료효과 비교

양상국,정상원,오미희,노용수,김홍섭,우응제,박승훈,이수열 건국대학교 의과학연구소 1999 건국의과학학술지 Vol.9 No.-

Biofeedback and pelvic floor electrical stimulation are new modalities that have been advocated for the treatment of female urinary incontinence. The aim of this study was to compare prospectively the therapeutic effect of Kontinence™(HMT Co., Korea) with Compact Elite™(ECL Co., France) in female urinary incontinence. All patients were evaluated with a complete history, physical examination, urinalysis, urine culture and urodynamic study. Eighteen patients were treated with Compact Elite™, and thirteen patients with Kontinence™. Enrolled patients had completed 8 office sessions consisting of biofeedback and intravaginal electrical stimulation according to the program of each machines. Overall treatment response was graded by patients on a scale of complete cure to aggravation. At two weeks after last session, overall improvement rate was 78% in Compact Elite™group and 92% in Kontinence™group(p>0.05). Overall patients' acceptability during treatment course was greater than 80% in both machines(p>0.05). There were no unexpected clinical findings during Kontinence™ treatment. After Kontinence™treatment, there were no laboratory changes including electrocardiography, complete blood count, liver function profile, and chest PA. These results showed that the biofeedback and electrical stimulation with Kontinence™was safe and moderately effective for female urinary incontinence comparable to Compact Elite™. However, long-term results of a larger patients are needed to ensure the therapeutic effect of Kontinence™.