Treatment of Radioactive Liquid Waste by the Forced-AirCirculation System

Tae-κuk Kim,IL Sik Kang,Jong-Sik Shon,Young-Gerl Ryu,Won-Hyuk Jang,Sang-Min Bae,Young-Yong Ji,Dae-Seok Hong,Kyung-Kil Kwak 한국방사성폐기물학회 2011 한국방사성폐기물학회 학술논문요약집 Vol.9 No.2

Artificial Neural Network for Modeling the Tensile Properties of Ferrite-Pearlite Steels: Relative Importance of Alloying Elements and Microstructural Factors

Tae‑Woon Hong,Sang‑In Lee,Jae‑Hyeok Shim,Myoung‑Gyu Lee,Joonho Lee,Byoungchul Hwang 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.10

An artificial neural network (ANN) model was developed to predict the tensile properties as a function of alloying elementand microstructural factor of ferrite-pearlite steels. The input parameters of the model were composed of alloying elements(Mn, Si, Al, Nb, Ti, and V) and microstructural factors (pearlite fraction, ferrite grain size, interlamellar spacing, and cementitethickness), while the output parameters of the model were yield strength and tensile strength. Although the ferrite-pearlitesteels have complex relationships among the alloying elements, microstructural factors, and tensile properties, the ANNmodel predictions were found to be more accurate with experimental results than the existing equation model. In the presentstudy the individual effect of input parameters on the tensile properties was quantitatively estimated with the help of theaverage index of the relative importance for alloying elements as well as microstructural factors. The ANN model attemptedfrom the metallurgical points of view is expected to be useful for designing new steels having required mechanical properties.

Cytokine and Tumor Environments

Jin Tae Hong1*, Ju Kyung Song, Sun Mi Kwon, Byung Woo Ahn, Youngsoo Kim, Sang Bae Han 충북대학교 동물의학연구소 2012 Journal of Biomedical and Translational Research Vol.13 No.1

Cytokines are known to function as regulatory molecules that can be produced by virtually every nucleated cell type in the body, including lymphocytes, monocytes/macrophages, epithelial cells, fibroblasts, and many others. Cytokines include lymphocyte-derived factors (lymphokines), monocyte-derived factors (monokines), hematopoietic factors (colony-stimulating factors), connective tissue/growth factors, and chemotactic chemokines. Cytokines released in response to infection can affect tumor development in different ways. When exposed to infectious agents, cytokines are secreted by sentinel cells, such as macrophages and dendritic cells. These cytokines include interleukin 1 (IL-1) and tumor necrosis factor-α, as well as others, such as IL-6, IL-12, and IL-18. When released in sufficient quantities, these molecules can cause inflammation. Chronic inflammation is highly associated with tumor initiation, promotion, and progression. In this article, we review the roles and mechanisms of cytokines in tumor development.

삼나무 (杉) 내한성 (耐寒性) 품종 선발에 관한 연구

홍성각,조태환,황증 ( Sung Gak Hong,Tae Hwan Cho,Jeung Hwang ) 한국산림과학회 1981 한국산림과학회지 Vol.51 No.1

This study was designed to know difference in degree of dehardening and rehardening respectively by artificial high and low temperature treatments among different clonal seedlings and seedlings from different seed sources of Cryptomeria japonica which have been grown under the cold areas in Japan and Korea. High temperature treatment was done with 15 to 20℃ under 100% relative humidity for one to nine days and low temperature treatment was carried with -7℃ for one to three days. Occasionaly, high temperature treatment was combined and followed by low temperature treatment. The ability of stem section to delay dehardening by high temperature treatment and/or to hasten rehardening by low temperature treatment was used as an indicator of adaptability under extreme temperature fluctuation in nature. Clones and seedlings from different seed sources which showed greater freezing resistance than others after artificial high and/or low temperature treatments were selected over two to three time periods: early winter, mid winter and early spring in 1977 to 1980. These were Seoul #7, and #9, Namboo #3, and #4, Sung-Kang #11, Chung-Sam #8 and Huek-Suk #9. These selected seedlings might have survival advantage to withstand early and late frost damage, especially the critical frost damage of the basal stem, since it was known to be induced by lowering freezing resistance of the basal part when exposed to the high temperature near the ground during the day. Large variation in freezing resistance and degree of dehardening and rehardening was found among clonal or seed sources and among individuals within a seed source, but was not related to the difference in climatic conditions where the parent trees was selected. These indicated the possibility of future breeding work for more cold resistant family of Cryptomeria japonica.

21가지 장미꽃 품종의 페놀성 화합물 함량 및 항산화 활성

조연재(Yeon Jae Jo),서정현(Jeong Hyun Seo),홍채영(Chae Young Hong),김성태(Seung Tae Kim),최은경(Ehn-Kyoung Choi),김윤배(Yun-Bae Kim),이준수(Junsoo Lee),정헌상(Heon Sang Jeong) 한국식품영양과학회 2021 한국식품영양과학회지 Vol.50 No.4

본 연구는 21품종의 장미꽃에 대한 식품 및 화장품 원료로 사용 가능성을 살펴보기 위해 페놀성 화합물과 항산화 활성을 평가하였다. 총 폴리페놀, 총 플라보노이드 및 타닌 함량은 러버샤이 품종에서 각각 379.70 mg GAE/extract g, 50.10 mg CE/extract g 및 339.44 mg TAE/extract g으로 높게 나타났으며, 칠백리 품종에서 각각 107.25 mg GAE/extract g, 9.46 mg CE/extract g 및 36.31 mg TAE/extract g으로 낮았다. 페놀산 함량은 총 폴리페놀 함량과 유사한 결과를 보였으며, 러버샤이 품종에서 27.40 mg/extract g으로 높았다. 안토시아닌은 대부분 cyanidin-3,5-diglucoside로 확인되었으며 총 안토시아닌 함량은 유니나 품종에서 8.80 mg/extract g으로 가장 높았다. ABTS 및 DPPH 라디칼 소거 활성은 각각 428.10 및 419.59 mg AAE/extract g로 러버샤이 품종에서 가장 높았으며, 항산화 활성과 페놀 화합물의 함량과 높은 양의 상관관계를 보였다. 이러한 결과는 러버샤이와 같은 항산화 활성이 뛰어난 품종들이 관상 목적뿐만 아니라 높은 기능성을 가진 식품 및 화장품의 원료로 사용 가능성이 있다고 판단된다. This study evaluated the functional components and antioxidant activities of 21 different rose flower extracts, to confirm their value as a food and cosmetics ingredient. The highest values of total polyphenol, flavonoid and tannin contents (379.70±1.64 mg GAE/extract g, 50.10±0.76 mg CE/extract g, and 339.44±1.20 mg TAE/extract g, respectively) were obtained in Lover Shy. The proanthocyanidin content ranged from 61.88 mg CE/extract g in the Unina cultivar to 5.34±0.13 mg CE/extract g in the Aileen cultivar. The phenolic acid content obtained was highest in the Lover Shy cultivar (27.40±0.26 mg/extract g), whereas highest levels of anthocyanin (8.83±0.03 mg/extract g) were obtained in the Unina cultivar. High ABTS and DPPH radical scavenging activities were determined in the Lover Shy cultivar (428.10±0.29 and 419.59±3.12 mg AAE/extract g, respectively). Taken together, these results indicate that the antioxidant activity and functional components of Lover Shy cultivar are superior, and this extract can potentially be applied as a food and cosmetic ingredient.

Vaccination and Complementary and Alternative Medicine in Patients with Inflammatory Bowel Disease

( Sung Bae Kim ),( Soo Jung Park ),( Sook Hee Chung ),( Kyu Yeon Hahn ),( Do Chang Moon ),( Sung Pil Hong ),( Jae Hee Cheon ),( Tae Il Kim ),( Won Ho Kim ) 대한장연구학회 2014 Intestinal Research Vol.12 No.2

Background/Aims: Vaccinations in patients with inflammatory bowel disease (IBD) are recommended to prevent infectiousdiseases. However, there are few reports of vaccination in IBD patients in Korea. The frequency of complementary and alternativemedicine (CAM) use is high despite its uncertain effectiveness. This study aimed to identify the rates of vaccination anduse of CAM in patients with IBD. Methods: A total of 219 patients attended an education session for IBD patients held at SeveranceHospital on March 23, 2013. We conducted a survey on vaccination and CAM use in IBD patients; 120 patients completedthe questionnaire. Results: The influenza vaccination rate was 44.2% and pneumococcal vaccination rate was 4.2%. Thirtyone(66%) patients were aware of the importance of vaccination. The vaccination rate was higher in patients who were awareof the importance of vaccination compared with that in patients who were unaware of the importance of vaccination (70.1%vs. 41.7%, P =0.004). The rate of CAM use was 30.0%. The most commonly used CAMs were oral products: vitamins (33.3%),red ginseng (25.0%), and probiotics (19.4%). Conclusions: Awareness of the importance of vaccination and actual vaccinationrates were low in IBD patients. Despite insufficient evidence on the effectiveness of CAMs in IBD patients, many patients usedCAMs. We believe that repeated education and promotion of vaccination are important. Further large-scale studies to investigatethe efficacy and safety of CAMs are warranted in patients with IBD. (Intest Res 2014;12:124-130)

Polydeoxyribonucleotides Improve Diabetic Wound Healing in Mouse Animal Model for Experimental Validation

( Tae-rin Kwon ),( Sung Won Han ),( Jong Hwan Kim ),( Byung Chul Lee ),( Jae Min Kim ),( Ji Yeon Hong ),( Beom Joon Kim ) 대한피부과학회 2019 Annals of Dermatology Vol.31 No.4

Background: Wound healing mechanisms is believed to have effects similar to wound healing disorders in diabetic patients, including abnormal inflammatory cells, angiogenesis disorders, and reduced collagen synthesis. Therefore, reestablishment of structural and promoted angiogenesis could be beneficial to promote wound healing process. Objective: Therefore, we investigated whether the polydeoxyribonucleotide (PDRN) that was self-production in Korea, could be useful as an intradermal injection for promoting wound healing. Also, we validate for wound healing effect of PDRN using healing-impaired (db/db) mice. Methods: In this study, we confirmed the effects of PDRN by creating wound models in in vitro and in vivo model. Using an in vitro wound healing assay, we observed that PDRN stimulated closure of wounded monolayers of human fibroblast cells. PDRN (8.25 mg/ml) or phosphate-buffered saline (0.9% NaCl) was injected once daily into the dermis adjacent to the wound for 12 days after skin injury. Results: Time course observations revealed that mice treated with PDRN showed accelerated wound closure and epidermal and dermal regeneration, enhanced angiogenesis. The wound area and depth decreased at 3, 6, 9, and 12 days after skin injury. Histological evaluation showed an increase of vascular endothelial growth factor, CD31, and collagen fibers in the PDRN group compared with the control group, indicating that PDRN was effective in the treatment of delayed wound healing caused by diabetes. Conclusion: This study suggests that our PDRN has a wound healing effect in transgenic animal models with cells and diabetes through angiogenesis. (Ann Dermatol 31(4) 403∼413, 2019)

Comparison between Single-phase Flow Model and Two-phase Flow Model : Containment Pool Flow and Transport of Debris

Tae Hyub Hong(홍태협),Sang Won Lee(이상원),Hyeong Taek Kim(김형택) 대한기계학회 2010 대한기계학회 춘추학술대회 Vol.2010 No.11

In the present study, a Computational Fluid Dynamics (CFD) analysis of the coolant flow in the containment pool is carried out and debris transportation is evaluated using the Lagrangian particle tracking method. The containment pool flow is simulated as a single-phase model and a two-phase model. In the single-phase model, the boundary representing a free surface is set to be a slip boundary condition. The two phase model uses Volume of Fluid (VOF) method. The transport of debris is calculated after achieving a steady state in the simulation of each model. The simulation results show that flow patterns are similar in both models, and the velocity magnitude calculated from the VOF model is less than that calculated from the single-phase model, in general.

[Poster] Adequate management of pulmonary metastases of colorectal cancers in terms of prognostic parameters : a retrospective analysis of 405 patients during 20 years

Tae Young Jang,Dong Kwan Kim,Seung Il Park,Yong Sik Yoon,Chan Wook Kim,Seok-Byeong Lim,Chang Sik Yu,Yong Sang Hong,Tae Won Kim,Jin Cheon Kim 대한외과학회 2011 대한외과학회 학술대회 초록집 Vol.2011 No.11

Increased Bone Mineral Density after Abstinence in Male Patients with Alcohol Dependence

Tae-Hong Song,Joo-Cheol Shim,Do-Un Jung,Jung-Joon Moon,Dong Wook Jeon,Sung Jin Kim,Minkyung Oh 대한정신약물학회 2018 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.16 No.3

Objective: This study aimed to compare the bone mineral density of male patients with alcohol dependence with that in healthy controls and to assess changes in bone density after abstinence. Methods: Forty-four inpatients with confirmed the Diagnostic and Statistical Manual of Mental Disorders, fourth edition diagnosis of alcohol abuse and 42 controls were recruited. Bone density was determined with dual-energy X-ray absorptiometry in the lumbar spine as well as in the femoral neck, trochanter, and Ward’s triangle regions of the proximal right femur. Results: There were no significant differences in age and body mass index between patients with alcohol dependence and healthy controls. In the alcohol dependence group, osteopenia and osteoporosis were found in 54.5% and 34.1% of the patients, respectively, whereas in the control group, the corresponding values were 45.2% and 11.9% (p=0.001). Although the actual bone density in the femur and the corresponding T-scores were significantly lower in the alcohol dependence group, no significant differences were found in the lumbar spine. In both groups, body mass index showed a significant correlation with bone mineral density in all areas. After 3 to 4 years of abstinence, bone density significantly increased in the lumbar and femur. Conclusion: We conclude that bone mineral density in patients with alcohol dependence was significantly lower than that in healthy controls, and the rates of osteopenia and osteoporosis are higher. Importantly, abstinence from alcohol increases bone density.