약물치료에 가역적 회복을 보인 갈색세포종에 동반된 확장성 심근증 1례

홍숙경,최현,이승철,천경일,김영철,한재룡,김미숙,정경태,박순창 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.2

Cone-beam CT를 이용한 제II급 부정교합 아동의 상기도 형태에 관한 3차원적 연구

홍지숙,김대성,오경민,김윤지,이규홍,박양호 대한치과교정학회 2010 대한치과교정학회지 Vol.40 No.3

Objective: The aim of this study was to evaluate the volumes and areas of the upper airways in children with Class II malocclusion, using three dimensional cone-beam computed tomography (CBCT) and to compare the volumetric and cross-sectional measurements and cephalometric variables to investigate possible relationships between the upper airway and facial morphology. Methods: CBCT scans were obtained from 37 subjects (17 boys and 20 girls; average age, 11.02 years). The upper airway volumes and areas were measured, and compared with cephalometric variables. Results: The area of the PNS-posterior plane (SPP) was significantly smaller in the Class II malocclusion group (p < 0.05). Also, the volumetric and cross-sectional measurements were lower in Class II than in Class I malocclusion groups, although the differences were not significant between the two groups (p > 0.05). The Class II malocclusion group showed significantly smaller values of PFH, mandibular body length, pog to N perp and showed larger values of FMA, ANB, and facial convexity than the Class I malocclusion group. The volume of the upper airway in front of PNS point (WN) showed negative correlation with ANB (p < 0.05). Conclusions: The Class II malocclusion group had a narrower upper airway associated with a decreased posterior facial height and a divergent growth pattern than the Class I malocclusion group. 성장기 아동의 상기도 협착은 두개안면 성장에 영향을 미칠 수 있다. 본 연구는 3차원 cone-beam computed tomography (CBCT)를 이용하여 제II급 부정교합 아동의 상기도 부피 및 단면적 계측치와 측모두부계측치를 비교하여 상기도와 안면 형태와의 연관성을 알아보고자 하였다. 37명의 아동(남자 17명, 여자 20명, 평균 연령 11.02세)의 CBCT를 촬영하였다. 연구 결과, 상기도의 PNS-posterior plane에서의 단면적(S_(PP))은 제II급 부정교합군에서 유의하게 작았다 (p < 0.05). 상기도 부피 계측치는 제II급 부정교합군에서 제I급 부정교합군보다 작았으나, 두 군 간 통계적으로 유의한 차이는 없었다. 제II급 부정교합군은 후안모고경(PFH), mandibular body length (p < 0.05), Pog to N perp (p < 0.01)에서 제I급 부정교합군보다 유의하게 작은 값을 보였고, FMA (p < 0.05), ANB, facial convexity (p < 0.01)는 유의하게 큰 값을 보였다. 제II급 부정교합군의 PNS 전방의 상기도 부피(W_(N))는 ANB difference 각도와 음의 상관관계를 보였다 (p < 0.05). 제II급 부정교합 아동은 상대적으로 좁은 상기도 부피를 가지며 이에 따른 감소된 후안모고경(PFH)과 하악골의 divergent한 안면 성장 양상을 보였다.

대구지방의 위암에 대한 병리조직학적 연구

홍석재,이태숙,최원희,이경철 영남대학교 의과대학 1985 Yeungnam University Journal of Medicine Vol.2 No.1

대구지방의 위암에 대한 병리조직학적 연구의 목적으로 대구 일원의 의료기관에서 수집한 위내시경 표본과 위절제수술 표본에 의해 위암으로 확진된 350예 및 130예의 조직학적 유형과 연령 분포는 다음과 같다. 1. 위내시경 표본 350예 중 선암이 344예(98.3%)로서 대부분을 차지하였으며 편평상피암과 미분화암은 불과 6예(1.7%) 뿐이었다. 선암 중에서는 tubular type가 215예(61.4%)로서 가장 많았고, 다음이 signet-ring cell type으로 92예(26.3%)이었다. 연령 분포는 50세대가 가장 많이 발생하여 120예(34.3%), 다음이 60세대로 81예(23.1%), 40세대가 76예(21.7%), 70세대가 33예(9.4%), 30세대가 32예(9.1%), 20세대가 8예(2.3%) 등의 순위였다. 2. 위절제수술 표본 130예중 가장 많은 조직학적 유형은 역시 선암으로 127예(97.7%)였고, 만성소화성 위궤양에서 발생한 것이 3예 있었다. 선암 중에서는 tubular type이 86예(66.2%)로 제일 많았고 다음이 signet-ring cell type였다. 연령분포는 50세대에서 50예(38.5%)로 가장 많이 발생하였고, 다음 60세대가 36예(17.7%), 40세대가 21예(16.2%), 30세대가 11예(8.5%), 70세대가 6예(4.6%), 그리고 10세대에서 1예(0.8%)있었다. For evaluation on the histopathologic studies, and age sex distribution of the gastric carcinomas in the Taegu Area, the gastrectomized and gastoroscopic biopsy materials were collected at the Department of Pathology, College of Medicine, Yeungnam University, and the analyzed results were as follows: 1. In total of 350 cases of gastroscopic biopsy materials adenocarcinomas are 344 cases (98.3%), squamous cell carcinomas and undifferentiated carcinomas are only 6 cases (1.7%). In adenocarcinomas the most of all are tubular type, 215 cases(61.4%). In age distribution the highest is the 50th age group, and 120 cases (34.3%), the next, 60th, 81 cases (23.1%), 40th, 76 cases (21.7%), respectively. 2. In total of 130 cases of gastrectomized materials adenocarcinomas are 127 cases (97.7%), and are the highest incidence, the next, carcinomas originated from chronic peptic ulcer of the stomach, and are 3 cases (2.3%). In adenocarcinomas the highest are tubular type, 86 cases (66.2%), the next, signet-ring cell type, 20 cases (15.4%). The highest age incidence of the age group is 50th, and the next, 60th, 40th, 30th, 70th and 10th age group, respectively.

不正咬合類型에 따른 齒軸傾斜度에 關한 頭部放射線計測學的 硏究

洪性德,車敬石 대한치과교정학회 1991 대한치과교정학회지 Vol.21 No.3

This research was performed to find out the adaptation patterns of maxillary and mandibular posterior teeth to the changes in relationships of vertical skeletal components, which constitute the skeletofacial complex. For this research, 61 adult malocclusion patients were chosen as subjects according to the Hellman's dental age with normally ranged FMN-A-B angle. These subjects were divided into 4 groups in maxilla and 3 groups in mandible according to mesiodistal inclinations of teeth. Following results were obtained after studying the relationships of the vertical skeletal components between each group. 1. Inspite of the fact that the FMN-A-B angle was within a normal range, the degree of mesiodistal inclinations of maxillary and mandibular posterior teeth showed differences in relation to the anteroposterior relationships of maxilla and mandible. In case where the FMN-A-B angle was large, the mesial inclinations of maxillary posterior teeth showed more increase from the posterior to the anterior, whereas in mandible it showed overall decrease. 2. The degrees of mesial inclinations of mandibular posterior teeth were increased when the angulations of lower facial height, occlusal plane angle and mandibular plane angle were greater. 3. The patterns of mesial inclinations of maxillary posterior teeth were varied according to the angulation of lower facial height. If relatively large, it showed more increase from the posterior to the anterior and it was decreased nearly consistent when the angulation was small. 4. The degrees of mesial inclinations of maxillary posterior teeth were decreased as the lower facial height, palatal plane angle, occlusal plane angle and the mandibular plane angle became greater.

不正咬合類型에 따른 齒軸傾斜度에 關한 頭部放射線計測學的 硏究

洪性德,車敬石 단국대학교 치의학연구소 1991 논문집 Vol.3 No.-

This research was performed to find out the adaptation patterns of maxillary and mandibular posterior teeth to the changes in relationships of vertical skeletal components, which constitute the skeletofacial complex. For this research, 61 adult malocclusion patients were chosen as subjects according to the Hellman's dental age with normally ranged FMN-A-B angle. These subjects were divided into 4 groups in maxilla and 3 groups in mandible according to mesiodistal inclinations of teeth. Following results were obtained after studying the relationships of the vertical skeletal components between each group. 1. Inspite of the fact that the FMN-A-B angle was within a normal range, the degree of mesiodistal inclinations of maxillary and mandibular posterior teeth showed differences in relation to the anteroposterior relationships of maxilla and mandible. In case where the FMN-A-B angle was large, the mesial inclinations of maxillary posterior teeth showed more increase from the posterior to the anterior, whereas in mandible it showed overall decrease. 2. The degrees of mesial inclinations of mandibular posterior teeth were increased when the angulations of lower facial height, occlusal plane angle and mandibular plane angle were greater. 3. The patterns of mesial inclinations of maxillary posterior teeth were varied according to the angulation of lower facial height. If relatively large, it showed more increase from the posterior to the anterior and it was decreased nearly consistent when the angulation was small. 4. The degrees of mesial inclinations of maxillary posterior teeth were decreased as the lower facial height, palatal plane angle, occlusal plane angle and the mandibular plane angle became greater.

자돈에 있어 게르마늄 용질액의 급여가 성장 및 혈액학적 변화에 미치는 영향

홍종욱,권오석,민병준,조진호,진영걸,손경승,강종옥,김인호 한국국제농업개발학회 2004 韓國國際農業開發學會誌 Vol.16 No.4

본 연구의 목적은 이산화게르마늄을 함유한 게르마늄 용질액을 자돈에 급여하였을 때 성장 및 혈액학적 변화에 미치는 영향을 조사하기 위하여 실시하였다. 3원 교잡종 자돈 60두 (평균체중 11.22±0.10㎏)를 공시하였다. 시험설계는 옥수수-대두박 위주의 대조구(CON)와, 대조구 사료내 게르마늄 용질액을 0.5 ppm 첨가한 구(GC0.5) 및 대조구 사료내 게르마늄 용질액을 1.0 ppm 첨가한 구(GC1.0)로 3개 처리를 하였다. 0-10일간 사양시험기간동안, 일당증체량에 있어서 GC0.5 처리구가 약간 높게 평가되었다(quadratic effect, P<0.02). 그러나 전체 시험기간동안, 일당증체량, 일당사료섭취량 및 사료효율에 있어서 처리구간에 유의적인 차이는 보이지 않았다. 영양소 소화율에 있어서는 GC0.5 처리구가 조회분(linear effect, P<0.01; quadratic effect, P<0.04), 칼슘(linear effect, P<0.01; quadratic effect, P<0.01), 인 (linear effect, P<0.02; quadratic effect, P<0.04) 소화율이 유의적으로 높게 평가되었다. 혈액내 neutrophil 농도에 있어서는 게르마늄 용질액의 첨가 수준이 증가함에 따라 유의적으로 증가하는 경향을 나타내었다(quadratic effect, P<0.02). 결론적으로, 자돈 사료내 게르마늄 용질액의 급여가 성장 및 혈액학적 수치에는 영향을 미치지 못하는 것으로 사료된다. This study was conducted to investigate the effects of dietary germanium colloid on the growth performance and hematological values in nursery pigs. Sixty pigs (11.22(0.10 ㎏ average initial body weight) were used in a 20 d growth assay. Dietary treatments included 1) CON (basal diet), 2) GC0.5 (basal diet+0.5 ppm germanium colloid) and 3) GC1.0 (basal diet+1.0 ppm germanium colloid). For d 0 to 10, pigs fed GC0.5 diet grew faster than pigs fed CON and GC1.0 diets (Quadratic effect, P<0.02). However, through the entire experimental period, no statistical differences were found for aver-age daily gain, average daily feed intake and gain/feed. Apparent digestibilities of crude ash (Linear effect, P<0.01; Quadratic effect, P<0.04), calcium (Linear effect, P<0.01; Quadratic effect, P<0.01) and phosphorus (Linear effect, P<0.02; Quadratic effect, P<0.04) in pigs fed GC0.5 diet were greater than for pigs fed CON and GC1.0. Neutrophil concentration in blood increased as the concentration of germanium colloid in the diets was increased with significant difference (Quadratic effect, P<0.02). In conclusion, growth performance and hematological values were not influenced by dietary germanium colloid.

동북아시아 다자안보협력체 구축 방안

박홍석,이현경 동아대학교 동아시아연구원 2006 동아시아 : 비교와 전망 Vol.5 No.-

본 논문은 동북아시아 다자안보협력체 구축 방안을 제시하는 데 그 목적을 두고 있다. 이를 구체화하기 위해 동북아시아와 한반도 지역에서의 미 · 일 · 중 · 러의 각축을 살펴보고. 동북아시아 다자안보협력체 창설에 대한 관련국들의 입장과 그 형성 방안을 제시한다. 아시아 태평양의 전 지역을 비교해 볼 때 동북아시아 지역의 다자협력 구도는 아직 미미한 상태다. 미 · 일 · 중 · 러 및 남한은 동북아시아의 평화와 안점을 위해 다자안보협력체의 창설 필요성에 공감하고 있으나 이 기구 창설을 위한 강한 의지를 보이고 있 지 않다. 그런데다 이 지역은 역내 국가들간 힘의 분포, 군비경쟁, 공통의 안보이익 부재, 각기 다른 안보적위협인석, 지역분쟁 및 영토분쟁 상존, 정치군사적 이해가 상충되어 있다. 더군다나 역사 · 정치 · 문화적 전통 등에 대한 공통성이 부재하고 상이한 문화 와 가치관이 존재한다. 그래서동북아시아 지역에 유럽형의 다자안보협력체를 형성하기가 쉽지 않다. 하지만 이 지역에 다자안 보협 력체가 구성되면 영전의 구도를 허물고 분쟁예방, 위기관리 갈등해소, 비군사적 안보위협 대처에 기여할 것이다. 동북아시아 다자안보협력체 구축이 현 단계에선 어렵다하더라도 역내 국가들이 CSCAP,ARF, NEACD 등 비정부간 안보협의체와 공동보조를 취하고 대화의 장을 넓혀 나간다면 다자안보협력체 창설을 위한 기반을 마련할 것이다. 이러한 토대 위에 역내 국가 들이 경제 · 환경·과학·기술 등 비정치군사적 사항에 효과적으로 대응함으로써 불안정성과 불확실성을 감소시키고 상호 신뢰를 구축 해 나간다면 동북아시아 다자안보협력체는 구축될 것이다. 그것은 동북아시아 평화체제를 구축하는 사전 단계이며, 세력균형의 틀 내에서 지역의 평화와 안점을 추구할 수 있다.

Quality of care in inflammatory bowel disease in Asia: the results of a multinational web-based survey in the 2nd Asian Organization of Crohn`s and Colitis (AOCC) meeting in Seoul

( Hye Kyung Song ),( Kang-moon Lee ),( Sung-ae Jung ),( Sung Noh Hong ),( Dong Soo Han ),( Suk-kyun Yang ) 대한장연구학회 2016 Intestinal Research Vol.14 No.3

Background/Aims: The quality of care in inflammatory bowel disease (IBD) has not been systematically estimated. The aim of this study was to investigate the current status of quality of IBD care in Asian countries. Methods: A questionnaire-based survey was conducted between March 2014 and May 2014. The questionnaire was adopted from “An adult inflammatory bowel disease physician performance measure set” developed by the American Gastroenterological Association. If the respondent executed the performance measure in more than 70% of patients, the measure was regarded as well performed. Results: A total of 353 medical doctors from Asia completed the survey (116 from Korea, 114 from China, 88 from Japan, 17 from Taiwan, 8 from Hong-Kong, 4 from India, 3 from Singapore, and 1 each from the Philippines, Malaysia and Indonesia). The delivery of performance measures, however, varied among countries. The documentation of IBD and tuberculosis screening before anti-tumor necrosis factor therapy were consistently performed well, while pneumococcal immunization and prophylaxis of venous thromboembolisms in hospitalized patients were performed less frequently in all countries. Physician awareness was positively associated with the delivery of performance measures. Variations were also noted in reasons for non-performance or low performance of quality measures, and the two primary reasons cited were consideration of the measure to be unimportant and lack of time. Conclusions: The delivery of performance measures varies among physicians in Asian countries, and reflects variations in the quality of care among the countries. This variation should be recognized to improve the quality of care in Asian countries.

세침 흡입 생검으로 진단된 간의 혈관근지방종 1 예

이경아,유은실,민영일,김해련,심기남,정훈용,양석균,홍원선,박의련,이문규 대한소화기학회 1999 대한소화기학회지 Vol.33 No.6

Hepatic angiomyolipoma is a rare benign tumor of the liver composed of blood vessel, smooth muscle cells, fat and myelocomponent. The preoperative diagnosed of the lesion is important because of its therapeutic implications. Radiologic findings are not specific because the composed elements are variable in proportion and distribution. Thus, the findings at computed tomography, ultrasono graphy and magnetic resonance imaging may be only suggestive and its definitive diagnosed requires histologic confirmation. We experienced a case of hepatic angiomyolipoma in patient with chronic hepatitis diagnosed preoperatively by fine-needle aspiraton biopsy under ultrasound guidance. To our knowledge, this is the first case of hepatic angiomyolipoma diagnosed preoperatively in Korea. We report it with review of literatures.

한국산 긴몰개(Squalidus gracilis majime, Cyprinidae)의 난발생

박경서,홍영표,문운기,최신석,안광국 한국육수학회 2005 생태와 환경 Vol.38 No.1

한국산 긴몰개 (Squalidus gracilis majimae)의 난발생 과정을 연구하기 위하여, 긴몰개의 친어와 생태적 조사는 충청남도 보령시에 위치한 보령댐과 웅천천에서 실시하였다. 자연 산란에 의해 수정된 난과 배 발생의 형태학적 설명은 다음과 같이 요약된다. 수정란의 형태는 둥글고, 점착성이 있으며 투명하였고, 수정란의 평균직경은 2.9±0.3 ㎜ (n = 30)였고, 유구가 존재하지 않았으며, 수정란의 발생은 수온 26±1.5℃에서 관찰되었다. 수정 후 20분에 배반이 형성되었으며,48분 뒤 2세포로 나뉘어졌고, 포배기는 수정 후 5시간 40분에 나타났으며, 낭배기는 수정 후 6시간 55분에 관찰되었다. 배체의 형성은 수정 후 12시간 58분부터 시작되었고, 안포와 9개의 체절이 수정 후 17시간 05분에 발견되었다. 수정 후 23시간 30분에 이포가 생겼으며, 25~26개의 체절과 함께 안포안의 렌즈가 수정 후 32시간 35분에 발견되었다. 수정 후 37시간 27분에 뇌의 분화와 함께 배체가 꿈틀거리기 시작했으며, 심장박동과 안포내의 흑색소포가 수정 후 44시간 46분에 발견되었다. 수정 후 50시간 36분 가슴지느러미의 형성과 함께 몸 부분의 흑색소포가 형성되는 것을 끝으로하여 수정 후 57시간 49분에 수정란은 부화되었다. 이때 갓 부화된 자어는 전장이 3.3±0.2 ㎜(n= 120)이었다. 본 연구 결과는 최근 수질오염 및 종 다양성 감소가 시급한 상황에서 종 및 개체군 보존에 기여할 것으로 사료된다. This study was conducted, based on the field survey and laboratory observations, to elucidate egg developmental processes and their characteristics of the Korean slender gudgeon, Squalidus gracilis majimae. For the experiments, the mature adults were collected at the Woongcheon-Cheon Stream and Boreung Reservoir located in Boreung City, Chungnam Province and eggs were obtained from the natural spawning area. Morphological characteristics of the egg and embryonic development were su㎜arized as follows: The shape of the fertilized egg was spherical, adhesive and transparent. The fertilized egg was 2.9±0.3 ㎜ (n = 30) in mean diameter under water temperature of 26 ± 1.5℃, light white in color and had no oil droplets. After 20 minutes from the time of fertilization, a blastodisc was formed and divided into two cells at 48 minutes after fertilization. The blastular stage occurred at 5 hours 40 minutes after fertilization and the gastrular stage was detected at 8 hours 41 minutes after fertilization. The beginning of embryo formation was observed at 12 hours 58 minutes after fertilization and optic vesicles and 9 somites were discovered at 17 hours 05 minutes after fertilization. Differentiation of brains and embryo wiggling were observed at 37 hours 27 minutes after fertilization. Heart beating and the formation of melanophores in optic vesicles were detected at 44 hours 46 minutes after fertilization. The formation of pectoral fins and melanophores in the body were discovered at 50 hours 36 minutes after fertilization. Hatching occurred at 57 hours 49 minutes after fertilization. The newly hatched larvae were 3.3 ±0.2 ㎜ (n = 120) in total length. We believe that these results may contribute the species and population conservations under the situation of accelerated water pollution and the decreases of its diversity.