地衣類의 脂質과 蛋白質 含量

徐信惠,李鴻善,崔璟姬,崔正渼 효성여자대학교 가정대학 학도호국단 1984 家政大論集 Vol.3 No.-

地衣類의 영양학적 가치를 조사하기 위하여 地衣類(지붕, 바위, 나무)와 석이의 總脂質 含量, 脂質 분포, 脂肪酸 조성, 蛋白質 含量을 측정하였다. 그 결과 총지질 함량은 100g당 석이는 3.47g, 바위에 地衣類는 3.40g, 지붕의 地衣類는 3.17g, 나무의 地衣類는 2.73g 이었고 TLC法에 의한 脂質의 분포는 석이와 地衣類 모두 cholesterol ester와 phospholipid 등이 있었고 나무 地衣類에는 TG 및 cholesterol의 흔적을 보였다. 지방산 조성은 대부분 C_12~C_18 fatty acid였고 그 중 C_18 : 1 C_18 : 2인 것이 50% 정도로 높게 나타났다. 나무의 地衣類에는 C_18 이상의 fatty acid도 상당량 분포되어 있었으며 C_20.4 fatty acid는 18.9%였다. 단백질 함량은 석이 6.60g, 地衣類는 8.22g이었다. To investigate the nutritional value of lichens, contents of total lipid, compositions of fatty acids, distributions of lipids and contents of total proteins in lichens (on the rock, roof and tree) and sogi were examined. The results were summarized as follow. The contents of total lipid in sogi, rock, roof, and tree lichens were 3.47±0.05%, 3.40±0.09%, 3.17±0.02%, 2.73±0.04% respectively. Lipids in all them were cholestrol ester and phospholidpid, and TG and cholesterol were existed only the lichen on the tree. Fatty acids were composed of that of carbon number 12-18; C_18:1 and C_18:2 were about 50%, Contents of total protein in sogi and lichen (roof) were 6.60% and 8.22% respectively.

과학영재교육 교사 교수방법 전문지식의 수준 분석

서혜애,박경희,박지은 이화여자대학교 교과교육연구소 2007 교과교육학연구 Vol.11 No.1

본 연구에서는 우리나라 과학영재교육을 담당하는 교사들의 과학영재교육 교수방법 전문지식의 수준을 조사하는 데 목적을 두었다. 2005년 기준 전국 16개 시·도 교육청 산하 영재학급 및 영재교육원에서 과학영재교육을 담당하는 교사 수는 총1,883명으로 조사되었다. 이 가운데 531명(28.2%)의 과학영재교육 교사는 ‘과학영재교육 교사 교수방법 전문지식 측정도구(서혜애·박경희, 2005)’에 응답하였으며, 응답한 교사의 교수방법 전문지식 수준은 최종학력, 연수이수여부, 학교급에 따라 차이가 있는 것으로 나타났다. ‘과학지식 및 과학교육학 지식’과 ‘영재교육학 지식’은 영재교육 연수 이수 유무와 관련 없이 교사의 성별 및 최종학력에 따라 차이를 보였으며, ‘과학영재교육과정 지식’은 교사가 어떤 영재교육 연수를 이수했는지, 어떤 학교급을 지도하고 있는 지에 따라 차이가 있는 것으로 나타났다. ‘교사 전문성 계발 지식’은 학교급, 성별에 따라 차이를 보였다. 연구결과에 근거하여 다음과 같이 과학영재교육의 질을 제고하는 방향을 제안하였다. 첫째, 효과적 과학영재교육교사 연수를 개발하기 위해서는, 연수기관은 연수 대상 교사의 학교급에 따라 연수프로그램의 교육내용을 달리하여 구성해야 할 것이다. 둘째, 과학영재교육 교사 임용정책에서는 최종학력 조건을 강화하고 교사 전문성 계발의 동기 수준을 고려하는 것이 바람직할 것이다. The research aims to investigate the status of teacher's professional knowledge level of teaching the gifted in science. As of 2005, there were 1,883 teachers who teach at gifted educational institutions affiliated with sixteen provincial offices of educations in Korea. Research subjects include 531 out of 1,883 teachers (28.2%) and they responded to the 'Science Teacher Scale of Professional Knowledge for Teaching the Gifted' (Seo & Park, 2005). It was found that there were significant differences in the levels of science teachers' professional knowledge for teaching the gifted in terms of highest degrees earned, school level, completion of inservice training programs of gifted education, etc. It was also found that ‘subject matter content knowledge in science and pedagogical content knowledge in science’ and ‘general pedagogical knowledge in gifted education’ varied along teachers' gender and highest degrees earned. ‘Science curriculum knowledge in gifted education’ were varied along completion of inservice teacher training programs and school levels. In conclusion, in order to raise the quality of gifted education, first, host institutions of inservice teacher training programs of gifted education are recommended to provide program contents in consideration with different schools levels of participating teachers. Second, policy makers may strengthen requirements of highest degrees earned for employing teachers in gifted education.

클로자핀이 치료 저항 정신분열병 환자의 삶의 질에 미치는 영향

서경란,이강욱,이소희 국립서울정신병원 2000 臨床硏究論文集 Vol.2000 No.-

구강 편평세포암종에서 E-cadherin 및 β-catenin 발현의 변화 : Correlation with Histologic Features and p53 Expression

서진건,권창석,박진배,윤혜경,김우형,이희철 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.4

Objective : Altered expression of cell adheion molecules is associated with biologic behavior of tumor. The aim of this study is to evaluate the expression pattern of E-cadherin, β-catenin and p53 protein according to histologic grade and invasion pattern of squamous cell carcinoma of the oral cavity and the relationship between E-cadherin, β-catenin and p53 protein expression. Methods and Material : The materials were fifty seven cses of squamous cell carcinoma, and clinicl parameers such as age, sex, tumor location, stage and recurrence were recorded. Histologic review was done based on histologic grade and invasion pattern(nodular vs infiltrative). Immunohistochemical stains for E-cadherin and β-ca tenin were interpreted based on staining pattern as los of membranous expression and cytoplasmic expression and p53 protein expression was defined as positive if more than 10% of nuclei were reactive. Statistical analysis between E-cadherin, β-catenin and p53 protein expressions and histologic grade and invasion pattern and the relationship between E-cdherin, β-catenin and p53 protein expressions were perfomed. Results : There wa positive correlation between higher histologic grade and infiltrative pattern. Loss of membranous expression and cytoplasmic expression of E-cadherin were noted in 33.3% and 57.9%, respectively, and loss of membranous expression of E-cadherin showed increaing tendency in poorly differentiated carcinomas, however, there was no significant difference of cytoplasmic expression rate of E-cadherin according to histoogic grade. Altered expression of E-cadherin was more frequent in poorly differentiated carcinomas. Loss of membranous expression and cytoplasmic expression of E-cadherin were more frequent in carinomas with infiltrative pattern than in carcinomas with nodular pattern, but their diferences were not significant, Loss of membranous expression and cytoplasmic expression of β-catenin were observed in 19.3% and 80.7%, respectively. Loss of membranous expression of β-catenin howed no positive correlation according to histologic grade and invasion pattern, but cytoplasmic expression rate of β-catenin was higher in poorly differentiated carcinomas and in carcinomas with infiltrative pettern. p53 protein expression rate was 45.6%, and showed invreasing tendency in poorly differentiated carcinomas, but no significant relationship with invasion pattern. There was an inverse relationship of loss of membranous expression and cytoplasmic expression of E-cadherin and β-catenin. Altered expression of E-cadherin was related to cytoplasmic expression of β-catenin, however, there were no significant relationship between altered expressions of E-cadherin and β-catenin and p53 protein expression. Conclusion : In squamous cell carcinomas of the oral cavity, altered expression of E-cadherin and β-catenin was more frequent in poorly differentiated carcinomas and in carcinomas with infiltrative pattern and there was positive correlation betwween altered expression of E-cadherin and β-catenin. These findings suggest that altered expressions of E-cadherin and β-catenin may have a role in the development of squamous cell carcinomas with aggressive biologic behavior. but altered explosions of E-cadherin and β-catenin. These findings suggest that altered expressions of E-cdherin and β-catenin my have a role in the development of squmaous cell carcinomas with aggressive biologic behavior. But altered expression of E-cadherin and β-catenin might not be related to p53 protein expression. Further study on genetic mutation related to altered expression of E-cadherin and β-catenin will be needed

3개 대학병원의 주 진단 코딩사례 평가

서순원,김광환,부유경,서진숙,서정돈,윤석준,이영성,이무식,정희웅 한국의료QA학회 2002 한국의료질향상학회지 Vol.9 No.1

Background : Coding of principal diagnosis is essential component for producing reliable health statistics. We performed this study to evaluate the current practice of principal diagnoses determination and coding, and to give some basic data to improve coding of principal diagnosis. Method : Nineteen medical record administrators(MRAs) of 3 university hospitals participated in coding principal Dx. From August 1, 2001 to August 31, 2001. From each hospital, 10 medical records of patients with high frequency disease were selected randomly. Each 10 medical records were grouped into three(A,B,C). Then, these 30 medical records were given to each MRAs for coding. At the same time questionnaire was given to each of them. Questions were to prove how they decide and code the principal diagnosis among many current diagnoses ; how they decide and code the principal diagnosis when day see irrelevant diagnosis recorded as the principal diagnosis in medical record, when only tentative diagnoses were recorded without final diagnosis, and when different diagnoses were recorded in different sheets of same record. Agreement of coding among 3 hospitals were compared and survey results were analysed with SAS 6.12. Results : Agreement of coding was found in medical records 5-6 of each 10 medical records. Causes of disagreement were as follows. Difference of clinician’s opinion from each hospital; mixed use of guideline from KCD-3 and guideline from DRG; difference in 4th digit classification according to the absence of pathology report in the medical record; difference of abbreviations among hospitals. 57.9% of decided principal diagnosis after consulting to KCD-3 guideline. When there were difficulties in determining the principal diagnosis, 42.1% of MRAs decided principal diagnosis after discussion with the physician, 26.3% after discussion with fellow MRAs. Conclusion : There were differences in coding among hospitals. To minimize the difference, we suggest the development of disease-specific guidelines for coding in addition to the current general guideline such as KCD-3. To do this, Coding Clinic which can produce guidelines is needed.

문주란과 아프리카문주란의 핵형분석

徐奉甫,李慶熙,金允景 慶北大學校 1992 論文集 Vol.52 No.-

The karyotypic analyses of Crinum asiaticum var. japonicum and C moorei var. album were carried out using conventional staining and Giemsa C-banding techniques, and distribution of B-chromosome was investigated. Chromosome compositions were diploid of 2n=22 in both species, of which five pairs including sat-chromosomes were submetacentrics, five pairs metacentrics and one pair subtelocentrics in C. asiaticum var. japonicum, but five pairs including sat-chromosomes were submetacentrics and the rest six pairs metacentrics in C. moorei var. album. Chromosome length was in a range of 5.6±0.4μm and 17.5±1.4 ㎛ in C. asiaticum var. japonicum, and 6.7±0.6㎛ and 15.8±4.7㎛ in C. moorei var. album. Consequently a little more variation in chromosome length was observed in C. asiaticum var. japonicum. Giemsa C-banding distribution of two species was very low, and thick C-bands were observed only near secondary constriction part of chromosome g. But there was a little difference in appearence of minor C-bands between two species, and this considered to be a characteristic of both species. B-chromosomes were observed only in C. asiaticum in a number of one to seven. But distinguishable morphological differences according to the different B-chromosome number were not observed.

간접부착술식시 치면과 레진 베이스의 간격 및 접착제에 따른 결합강도

서미영,박병주,경희문,황현식 전남대학교 치의학연구소 2001 구강과학 Vol.13 No.3

The purpose of this study was to evaluate the feasibility of the combined use of paste resin with sealant as an adhesive of the indirect bonding. The resin bases made of lighcured resin were bonded to the bovine incisors at a distance of 0.0, 0.2 or 0.4mm using the sealant only or the mixture of sealant and paste resin. Bond strength of each group was measured using universal testing machine. The results were as follows: 1. The bond strength was reduced in both groups as the distance between enamel surface and resin base increased. 2. The bond strength showed no statistical difference between two groups in case the distance between enamel surface and resin base was 0.0mm. 3. In case the distance between enamel surface and resin base was 0.2 or 0.4mm, the sealant with paste resin group showed significantly higher bond strength than the sealant only group. The results of the present study indicate that the use of paste resin with sealant may be desirable as an adhesive in indirect bonding, particularly in case a gap is suspected between enamel surface and resin base.

보건소 건강증진사업 수행과정의 질 평가

서영준,정애숙,박태선,김주경,박남수,이희원 韓國保健敎育.健康增進學會 2003 보건교육건강증진학회지 Vol.20 No.1

This study purports to assess the process quality of health promotion programs at public health centers. The sample used in this study consisted of 242 public health centers in South Korea. Data was collected with self-administered questionnaires between September. 3rd to September. 23rd in 2002. The 95 returned questionnaires were analyzed by SPSS 11.0 version. The major findings are as follows; There is a need to improve (1) a procedure for reviewing and analyzing strategic planning, (2) the quality of the staff in charge of program management, (3) the function of planning and training for monitoring and evaluation, (4) the ability of program managers in advising and consulting with clients, and (5) a procedure for organizing resources and information. In conclusion, in order to improve the process quality of health promotion programs at public health centers, integrated support from various institutions such as public health centers, community, regional and national health authorities and administrative departments is required.

비만을 동반한 위암 환자에서 두 병을 같이 수술 치료한 경험(증례)

최경현,윤기영,문형환,신연명,서경원,안수미,송윤미,석정희,정경연,이은하 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.3

Obesity is growing problem in Korea. We had a case of bariatric surgery during gastric cancer operation. Patient was 29 year old Korean lady with early gastric cancer located in the lesser curvature side of the middle 1/3 of the stomach. Her body weight was 89 kg, height 163 cm, and thus body mass index was 33.5 kg/m2. Preoperative blood pressure was 130/90 mmHg, hemoglobin 12.9 g/dL, total lymphocyte count 3,280/mL, serum albumin 4.3 g/dL, CEA 1.1 ng/mL, CA 19-9 9.1 ng/mL, and alpha fetoprotein 2 ng/mL. Another associated disease was right thyroid follicular neoplasm. The chest X-ray was normal. After IM injection of 2,500 units of heparin 30 minutes before the induction of general anesthesia, she received curative subtotal gastrectomy and Roux en Y gastrojejunostomy when a malabsorption loop of 120 cm jejunum was incorporated between the Treitz ligament and the end to side jejuno-jejunostmy site at May 29th 2006. Her postoperative course was uneventful except a minor wound seroma and the elevations of serum amylase(up to 4 folds) and lipase(up to 2 folds). She lost her body weight 9 kg in 5th, 21 kg in 7th, and 27 kg in 10th postoperative months to became 61.5 kg. On follow up exams in July 2008, she gained 4 kg to overcome her weakness and fatigue. From the above result, the incorporation of a malabsorption loop during reconstruction phase of gastric cancer operation was a good option for obese gastric cancer patients especially in cases of early gastric cancer.

자연계열 글쓰기 교육의 이론과 실제

서경희 이화어문학회 2008 이화어문논집 Vol.26 No.-

본고는 자연계열 전공생들을 대상으로 하는 글쓰기 수업의 현 단계를 점검하고, 이를 바탕으로 자연계열 글쓰기 교육에서 수강생들과 공유할 수 있는 문제와 실제 수업에서 활용할 수 있는 사례들을 조사하여, 제시하는 것을 목적으로 한다. 자연계열 전공생을 대상으로 하는 글쓰기 수업에서, 전문화되고 특화된 전공 영역의 문제의식과 글쓰기 형식, 표현 방식 등을 타 영역과 공유할 수 있는 방안을 모색하고 이를 실습함으로써 전공 영역을 뛰어넘는 의사소통의 능력을 갖출 수 있도록 모형을 제시한다. 이러한 글쓰기 교육은 자연계열 전공 수강자들의 글쓰기, 말하기 등의 의사 전달 능력을 함양하는 것에서 더 나아가, 타 영역과 공유할 수 있는 표현 방식을 훈련하여 제반 학문과 소통하는 데에 기여하고자 한다. The purpose of this thesis is to check the present stage of writing class that students who major in natural sciences take. It is also to examine and to show the problems that the students recognize in writing class and the examples that can be used in the class. Writing class for students who major in natural sciences will give them a chance to find ways to share a critical mind for their major, the form of writing and ways of expression with other provinces. This class gives an example to have them improve their communication capacity beyond their major. This writing education aims at helping communication between specialized studies by practicing ways of expression that are shared with other provinces as well as improving writing and speaking skill of the students who major in natural sciences.