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      • KCI등재후보

        노동과 인간의 미래 ―인간의미의 원천으로서 노동의 미래에 대한 신학적 전망

        이상은 ( Lee¸ Sangeun ) 서울신학대학교 기독교신학연구소 2020 神學과 宣敎 Vol.59 No.-

        본문은 기술혁명시대에 제기되고 있는 일과 인간의 관계에 대한 설명을 모색하고자 하고 있다. 본문은 첫째, ‘일’로부터의 방면이 본질적으로 목표가 될 수 있는 주제인가라는 질문을 제기하고자 한다. 둘째, ‘일’이 인간의 본질적 부분을 구성하는 주제이며, 변화된 환경 속에서도 이러한 주제에 대한 고찰이 주어져야 한다는 입장을 피력한다. 셋째, 미래시대를 위해 바람직한 기독교 노동관을 구성하기 위한 단상을 제공하고자 한다. 이러한 주제를 다루기 위해 본문은 특히 몰트만(J. Moltmann)과 볼프(M. Volf)가 전개했던 노동에 대한 단상을 중심으로 하는 신학적 대화를 전개해 나가고 있다. 본문은 기독교적 관점에서 노동은 어떻게 보아야 하는가에 대해 다루고 있다. 노동을 인간의 형벌로 보는 부정적 관점과 인간의 자기실현이라고 하는 차원에서 노동을 관찰하는 긍정적 관점 사이의 양가감정 사이에서 기독교적 노동관에 대해 고찰하고 있으며, 몰트만의 관점과 함께 역사적 고찰을 통해 이 문제를 다루고 있다. 본문은 또한 인간의 미래를 위해 노동개념 자체에 대한 고찰 속에 성서적, 신학적 노동관을 수립하고자 시도하고 있다. 하나님의 창조를 반영하는 것으로서의 노동, 산출과 안식을 포괄하는 관계적 개념으로서의 노동, 그리고 개인이 아니라 공동체를 지향하는 것으로서의 노동을 구현하면서 인간의 미래를 위한 노동개념을 구사해나가고자 하고 있다. 본래의 창조적 기쁨을 누리는 인간으로서의 호모 루덴스를 지향하는 노동개념을 생각하고자 하고 있으며, 인간상호간의 결핍과 보완을 통한 통전적 장을 지향하고자 하고 있다. This text deals with the relationship between human work and human being itself in the era of technological revolution. It raises at first a question whether it is proper to seek emancipation from the work, especially from a christian point of view. Second, it expresses the position that ‘work’ constitutes the essential part of human being and that consideration should be given to this subject, even in the changed environment. Third, it tries to provide a thought for constructing the concept for the Christian ethics of labour for the future age. In order to deal with this subject, this study is centering on the theological work of J. Moltmann and M. Volf. Based on it, this study examines how the Christian ethics could gives an answer to the question of labour, between the negative viewpoint of labor as a punishment for human being and the positive viewpoint of observing labor on the level of human self-achievement. Simultaneously, this text is also attempting to establish a biblical and theological work in consideration of the concept of labor itself for the future of mankind. It suggests that the concept of labour is to be understood in the light of God’s creation, and labour as a community-oriented performance. Furthermore, it considers the concept of homo ludens whether it could reflect on the concept of labour as creative joy and complement of human mutuality in the field of labour.

      • KCI등재

        Clinical Experiences of Amplitude-integrated Electroencephalographic Monitoring in Neonatal Intensive Care Unit

        ( Sangeun Lee ),( Sujin Choi ),( Yun Jeong Lee ),( Jisook Kim ),( Sook-hyun Park ),( Eun Joo Lee ) 대한주산의학회 2020 Perinatology Vol.31 No.4

        Objective: The purpose of this study was to analyze the clinical experience of amplitude-integrated electroencephalogram (aEEG) in the neonatal intensive care unit (NICU) and to evaluate the usefulness of the aEEG and to determine whether an EEG could help to identify high risk infants with later epilepsy. Methods: Clinical data of 200 newborn infants admitted to the NICU and monitored with aEEG were reviewed retrospectively. A single- or two-channel aEEG (electrode placement P3-P4 for single, C3-C4 and P3-P4 for two) was recorded continuously by using gold cups. Background activity was assessed based on voltage and pattern recognition methods. To assess for differences in later epilepsy among infants with abnormal versus normal results, chi-square test was employed with odd ratio. Results: Overall, 200 newborn infants were included. About half showed abnormal findings on aEEG monitoring with 34.5% abnormal background activity, 30.0% abnormal cyclicity, and 30.0% with seizures. The odd ratio for an abnormal trace on aEEG to predict later epilepsy was 7.9 (95% confidence interval; 2.8-22.0; P<0.001). Conclusion: aEEG monitoring is useful for cerebral monitoring in NICU. aEEG monitoring enabled to assess the cerebral integrity of infants by measuring background activities and detecting seizures and help to identify high-risk infant for later epilepsy.

      • Elevated Red Blood Cell Distribution Width as a Simple Prognostic Factor in Patients with Symptomatic Multiple Myeloma

        Lee, Hyewon,Kong, Sun-Young,Sohn, Ji Yeon,Shim, Hyoeun,Youn, Hye Sun,Lee, Sangeun,Kim, Hyun Ju,Eom, Hyeon-Seok Hindawi Publishing Corporation 2014 BioMed research international Vol.2014 No.-

        <P>Red blood cell distribution width (RDW) is a parameter reported in complete blood cell count tests, and has been reported as an inflammatory biomarker. Multiple myeloma (MM) is known to be associated with inflammatory microenvironments. However, the importance of RDW has been seldom studied in MM. For this study, 146 symptomatic myeloma patients with available RDW at diagnosis were retrospectively reviewed, and their characteristics were compared between two groups, those with high (>14.5%) and normal (≤14.5%) RDW. RDW was correlated to hemoglobin, MM stage, <I><I>β</I></I>2-microglobulin, M-protein, bone marrow plasma cells, and cellularity (<I>P</I> < 0.001). During induction, overall response rates of the two groups were similar (<I>P</I> = 0.195); however, complete response rate was higher in the normal-RDW group than it was in the high-RDW group (<I>P</I> = 0.005). With a median follow-up of 47 months, the normal-RDW group showed better progression-free survival (PFS) (24.2 versus 17.0 months, <I>P</I> = 0.029) compared to the high-RDW group. Overall survival was not different according to the RDW level (<I>P</I> = 0.236). In multivariate analysis, elevated RDW at diagnosis was a poor prognostic factor for PFS (HR 3.21, 95% CI 1.24–8.32) after adjustment with other myeloma-related prognostic factors. RDW would be a simple and immediately available biomarker of symptomatic MM, reflecting the systemic inflammation.</P>

      • KCI등재

        Estimating magnitude of suspended sediment transport in ungauged east coastal zone

        Lee, Sangeun,Kang, Sanghyeok 한국수자원학회 2018 한국수자원학회논문집 Vol.51 No.2

        토사유출에 대한 자료는 극히 제한되어 있으며 이에 대한 관측지점 또한 대하천에 국한되어 있다. 더욱이 대하천 하류의 해안부근 유사량 자료는 전무한 실정이다. 본 연구는 지속적인 토사유입으로 인하여 그 면적이 줄어들고 있는 동해안의 석호인 유역면적 8.2km²의 향호를 대상으로 토사량 유출량을 계산하여 유호성을 검증하였다. 그 결과 향호로 유입되는 비유사량은 약 280 t/km²/yr 이었으며 유사전달률은 약 0.78이었다. 본 접근방법은 현재 육역화가 대부분 진행되어 있는 동해안 석호의 토사유입 과정을 유추하는데 유효한 자료가 될 것으로 기대한다. Coastal sediment archives are used as indicators of changes on shore sediment production and fluvial sediment transport, but rivers crossing coastal plains may not be efficient conveyors of sediment to the coast. In some case there is a net loss of sediment in lower coastal plain reaches, so that sediment input from an upstream exceeds the sediment yield (SY) at the river mouth. The main source of sediment in coastal area is the load from land. In Korea, data on suspended SY are limited owing to a lack of logistic support for systematic sediment sampling activities. This paper presents an integrated approach to estimate SY for ungauged coastal basins, using a soil erosion model and a sediment delivery ratio (SDR) model. For applying the SDR model, a basin specific parameter was validated on the basis of field data. The proposed relationships may be considered useful for predicting suspended SY in ungauged basins that have geologic, climatic and hydrologic conditions similar to the study area.

      • SCIESCOPUSKCI등재

        Serum immunoglobulin E (IgE) levels and dietary intake of Korean infants and young children with atopic dermatitis

        Sangeun Lee,Kangmo Ahn,Hee Young Paik,Sang-Jin Chung 대한지역사회영양학회 2012 Nutrition Research and Practice Vol.6 No.5

        Atopic dermatitis (AD) has become a serious epidemic in Korean children. We aimed to investigate the association between vitamin C, E and other nutrients, and serum total IgE/specific IgE levels in children with AD. A total of 119 children (0-24 mo) diagnosed with AD were recruited for this cross-sectional study from a medical center in Seoul. A 24 h recall was used to assess dietary intakes. Serum total and six food-allergen specific IgE levels were measured by CAP-FEIA. Serum vitamin E was also measured but only in 25 out of the total 119 participants. Multiple linear regression analysis was performed to estimate the coefficients between serum IgE levels and dietary intake as well as serum vitamin E. Serum vitamin E levels showed a significantly inverse association with serum total IgE and all specific IgE levels (P < 0.05). Fat intake was inversely related with specific-IgEs for egg whites, milk, buck wheat, soy, and peanuts (P < 0.05). Positive associations were found between carbohydrate (CHO) intake and total IgE and specific IgEs to egg whites, milk, soy, and peanuts (P < 0.05). Vitamin C, E and n-3/n-6 fatty acids were not related with serum total IgE and specific IgE levels except for the association between buck wheat and vitamin E. In addition, there were no significant differences between males and females in dietary intake and serum IgE levels by student’s t-test. Although dietary vitamin E showed no association with serum IgE levels, serum vitamin E drew a significant inverse relationship with serum IgE levels. The evidence seems to suggest that vitamin E may possibly lower total and specific-IgEs in children with AD, and that it is important to maintain a relatively high serum vitamin E level in children with AD.

      • Fusion protein of retinol-binding protein and albumin domain III reduces liver fibrosis

        Lee, Hongsik,Jeong, Hyeyeun,Park, Sangeun,Yoo, Wonbaek,Choi, Soyoung,Choi, Kyungmin,Lee, Min-Goo,Lee, Mihwa,Cha, DaeRyong,Kim, Young-Sik,Han, Jeeyoung,Kim, Wonkon,Park, Sun-Hwa,Oh, Junseo BlackWell Publishing Ltd 2015 EMBO molecular medicine Vol.7 No.6

        <P>Activated hepatic stellate cells (HSCs) play a key role in liver fibrosis, and inactivating HSCs has been considered a promising therapeutic approach. We previously showed that albumin and its derivative designed for stellate cell-targeting, retinol-binding protein–albumin domain III fusion protein (referred to as R-III), inactivate cultured HSCs. Here, we investigated the mechanism of action of albumin/R-III in HSCs and examined the anti-fibrotic potential of R-III <I>in vivo</I>. R-III treatment and albumin expression downregulated retinoic acid (RA) signaling which was involved in HSC activation. RA receptor agonist and retinaldehyde dehydrogenase overexpression abolished the anti-fibrotic effect of R-III and albumin, respectively. R-III uptake into cultured HSCs was significantly decreased by siRNA-STRA6, and injected R-III was localized predominantly in HSCs in liver. Importantly, R-III administration reduced CCl<SUB>4</SUB>- and bile duct ligation-induced liver fibrosis. R-III also exhibited a preventive effect against CCl<SUB>4</SUB>-inducd liver fibrosis. These findings suggest that the anti-fibrotic effect of albumin/R-III is, at least in part, mediated by downregulation of RA signaling and that R-III is a good candidate as a novel anti-fibrotic drug.</P>

      • KCI등재

        Curriculum Reform for the Development of Key Competencies in Korean Middle Schools

        Sangeun Lee(이상은) 학습자중심교과교육학회 2019 학습자중심교과교육연구 Vol.19 No.22

        이 글의 목적은 국내 중학교에서의 핵심역량 개발을 위한 교육과정 개혁 동향을 분석하는 데 있다. 이를 위한 연구 문제는 다음 세 가지이다. 첫째, ‘의도된 교육과정’의 측면에서, 핵심역량 개발을 위해 국가 교육과정 수준에서 설계된 국내 중학교 교육과정의 특징은 무엇인가? 둘째, ‘실행된 교육과정’의 측면에서, 이와 같은 교육과정 개혁으로 인해 교실 수준에서 교사들이 겪는 변화와 도전과제는 무엇인가? 셋째, ‘경험된 교육과정’의 측면에서, 학생들은 새로운 교육과정 변화와 자신들의 핵심역량 발달 정도에 대해 어떻게 인식하는가? 첫 번째와 두 번째 연구 문제를 살펴보기 위해서는 문서 분석 방법을 활용하였고, 세 번째 연구 문제를 살펴보기 위해서는 중학생들을 대상으로 한 설문조사 결과를 활용하였다. 연구 결과, 최근 국내에서 이루어지는 중학교의 핵심역량 개발을 위한 교육과정 개혁은 먼저의도된 교육과정의 측면에서 간학문적 접근의 확대, 학습량 감축, 학생들의 과목 선택권 확 대 등의 특징을 보였다. 다음으로, 실행된 교육과정의 측면에서 수업은 학생 참여형 활동이 강조되고, 평가는 학생들의 성장 과정에 초점을 둔 과정 평가와 수행 평가의 형태가 확대되었다. 이러한 변화는 교사들 간의 학습 공동체를 활성화하며, 나아가 교사들에게 학교 밖 지역사회와의 협력을 요구하였다. 그럼에도 불구하고 교사들은 실행 과정에서 업무량 증가, 관련 자료 부족 등과 관련하여 어려움과 불만을 나타냈다. 마지막으로, 경험된 교육과정의 측면에서 핵심역량 함양을 위한 교육과정 변화를 경험한 학생들이 그렇지 않은 학생들에 비해 학교 교육과정에 대한 만족도 및 자신의 핵심역량 발달 정도에 관해 긍정적인 응답을 하였다. 그러나 이와 동시에 학생 및 학부모들의 학력 저하에 대한 우려도 공존하고 있었다. 결론 부분에서는 이러한 국내 핵심역량 개발을 위한 교육과정 변화가 ‘21세기 진보주의 교육의 부활’이라는 특징을 나타낸다는 점을 논의하였다. The topic of “key competencies” has received increasing attention worldwide within the discourse on curriculum reform. Recently, in South Korea, a new form of curriculum for students’ development of key competencies through revised national curriculum and a new educational policy, “Free Semester Program” has been adopted. The purpose of this study is to examine the recent trends of curriculum reform for students’ key competencies in Korean middle schools. To analyze them, the present study used the conceptual framework of curriculum expression, which distinguishes between the intended curriculum, the implemented curriculum, and the experienced curriculum. This study addressed the following research questions. (1) What are the characteristics of the “intended curriculum” designed to develop students’ key competencies in Korean middle schools? (2) What are the changes and challenges faced by teachers in aspect of “implemented curriculum” intended to pursue key competencies? (3)What are the students’ perception on the new curriculum and their development of key competencies in terms of “experienced curriculum?” To deal with this research questions, this study conducted document analysis and reanalyzed data from a survey questionnaire to middle school students in South Korea.

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