Detection of pathogenic microorganisms using biosensor based on multi-walled carbon nanotubes dispersed in DNA solution

Nguyen Thi Thuy,Phuong Dinh Tam,Mai Anh Tuan,Anh-Tuan Le,Le Thi Tam,Vu Van Thu,Nguyen Van Hieu,Nguyen Duc Chien 한국물리학회 2012 Current Applied Physics Vol.12 No.6

The present paper introduces a facile and cost-effective route for the direct dispersion of multi-walled carbon nanotubes (MWCNTs) in DNA solution. Their application in detecting Escherichia coli O157:H7using DNA biosensorwas demonstrated. The dispersion state of theMWCNTswas characterized via UVeVis spectroscopy, transmission electron microscopy, and field emission scanning electron microscopy. The interaction between DNA sequence and the MWCNTs was investigated using Raman spectroscopy and Fourier transform infrared spectroscopy. As-obtainedMWCNT solutionwas used in the preparation of DNA sensor. Results revealed that the developed DNA sensor can detect a DNA target as low as 1 nM in a buffer solution. The sensitivity of the DNA sensor reached approximately 0.19 nM/mV. The effect of dispersion parameters, including pH values, DNA concentration, ion strength, and sonication time, on sensor response was also studied. TheDNA sensor can respondwell to 120 min of sonication time, a pH value of 9, and 20 mM of DNA sequence concentration. The results of the present study showed a potential application of the DNA sensor in the detection of Escherichia coli O157:H7.

Advanced Magnetic Materials Produced by Using Rapid Quenching Technology

Nguyen Hoang Nghi,Nguyen Van Dung,Trinh Thi Thanh Nga,Bui Thi Khanh Nhung,Mai Thanh Tung,Nguyen Huu Tinh,Hoang Nhat Hieu,Bui Xuan Chien,Nguyen Thi Hong Tam 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.52 No.6

Amorphous alloys produced by using a rapid quenching technique are considered to be a precursor for producing nanosized and multiphase structures by precipitation (the top-down method). By using this technique, several new magnetic materials with different magnetic properties based on different physical mechanisms have been manufactured and investigated. Three new magnetic materials, a nanocrystalline soft magnetic material, a soft-hard permanent magnet and a Me-3d granular alloy with a GMR effect, what were prepared under local conditions, are presented and discussed in the experimental point of view. Amorphous alloys produced by using a rapid quenching technique are considered to be a precursor for producing nanosized and multiphase structures by precipitation (the top-down method). By using this technique, several new magnetic materials with different magnetic properties based on different physical mechanisms have been manufactured and investigated. Three new magnetic materials, a nanocrystalline soft magnetic material, a soft-hard permanent magnet and a Me-3d granular alloy with a GMR effect, what were prepared under local conditions, are presented and discussed in the experimental point of view.

Anaplasma marginale and A. platys Characterized from Dairy and Indigenous Cattle and Dogs in Northern Vietnam

Nguyen Thi Hong Chien,Thi Lan Nguyen,Khanh Linh Bui,Tho Van Nguyen,Thanh Hoa Le 대한기생충학ㆍ열대의학회 2019 The Korean Journal of Parasitology Vol.57 No.1

Anaplasma marginale and A. platys were detected and characterized (16S rDNA sequence analysis) from dairy and indigenous cattle, and the latter in domestic dogs in Vietnam. A phylogenetic tree was inferred from 26 representative strains/species of Anaplasma spp. including 10 new sequences from Vietnam. Seven of our Vietnamese sequences fell into the clade of A. marginale and 3 into A. platys, with strong nodal support of 99 and 90%, respectively. Low genetic distances (0.2-0.4%) within each species supported the identification. Anaplasma platys is able to infect humans. Our discovery of this species in cattle and domestic dogs raises considerable concern about zoonotic transmission in Viet- nam. Further systematic investigations are needed to gain data for Anaplasma spp. and members of Anaplasmataceae in animal hosts, vectors and humans across Vietnam.

A facile thermal evaporation route for large-area synthesis of tin oxide nanowires: Characterizations and their use for liquid petroleum gas sensor

Nguyen Van Hieu,Le Thi Ngoc Loan,Nguyen Duc Khoang,Nguyen Tuan Minh,Do Thanh Viet,Do Cong Minh,Tran Trung,Nguyen Duc Chien 한국물리학회 2010 Current Applied Physics Vol.10 No.2

In this paper, a very simple procedure was presented for the reproducible synthesis of large-area SnO2nanowires (NWs) on a silicon substrate by evaporating Sn powders at temperatures of 700, 750, and 800 ℃. As-obtained SnO2 NWs were characterized by field emission scanning electron microscopy (FESEM),transmission electron microscopy (TEM), X-ray diffraction (XRD), and Raman spectroscopy. They revealed that the morphology of the NWs is affected by growth temperature and the SnO2 NWs are single-crystalline tetragonal. The band gap of the NWs is in the range of 4.2–4.3 eV as determined from UV/visible absorption. The NWs show stable photoluminescence with an emission peak centered at around 620 nm at room-temperature. The sensors fabricated from the SnO2 NWs synthesized at 700 ℃ exhibited good response to LPG (liquefied petroleum gas) at an operating temperature of 400 ℃.

Economic Growth, Financial Development, Transportation Capacity, and Environmental Degradation: Empirical Evidence from Vietnam

Van Chien NGUYEN,Duc Binh VU,Thi Hoang Yen NGUYEN,Cong Do PHAM,Tuyet Ngan HUYNH 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.4

In recent years, there has been a substantial theoretical and empirical study on the role that financial market development has significantly played in promoting economic growth and development in the world. The development of an economy requires the financial industry to be developed. In the context of rapid economic development, global warming has become a serious problem with issues such as rising average temperatures, climate change, rising sea level, and increasing carbon dioxide emissions. This study aims to examine the influence of economic growth, financial development, transportation capacity, and environmental degradation. Using time-series data from 1986 to 2019 and environmental degradation being measured by CO2 emissions, the study employs a quantity of ample unit root tests, the structural break unit root tests, Autoregressive Distributed Lag (ARDL), and cointegration bounds test. The results show that there is a significant long-term cointegration among study variables. Empirical findings also indicate that an increase in per capita GDP and financial development worsens environmental quality whereas transportation capacity and foreign investment can improve environmental quality.

Impact of Exchange Rate Shocks, Inward FDI and Import on Export Performance: A Cointegration Analysis

NGUYEN, Van Chien,DO, Thi Tuyet Korea Distribution Science Association 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.4

The study aims to examine the effects of inward every presence of foreign investment, import, and real exchange rate shocks on export performance in Vietnam. This study employs a time-series sample dataset in the period of 2009 - 2018. All data are collected from the General Statistics Office of Ministry of Planning and Investment in Vietnam, World Development Indicator and Ministry of Finance, State Bank of Vietnam. This study employs the Augmented Dickey-Fuller test and the vector error correction model with the analysis of cointegration. The results demonstrate that a higher value of import significantly accelerates export performance in the short run, but insignificantly generates in the long run. When the volume of registered foreign investment goes up, the export performance will predominantly decrease in the both short run and long run. Historically, countries worldwide are more likely to devaluate their currencies in order to support export performance. According to the study, the exchange rate volatility has an effect on the external trade in the long run but no effect in the short run. Finally, Vietnam's export performance converges on its long-run equilibrium by roughly 6.3% with the speed adjustment via a combination of import, every presence of foreign investment, and real exchange rate fluctuations.

Targeted and controlled drug deliveryl system loading artersunate for effective chemotherapy on CD44 overxpressing cancer cells

( Tuan Hiep Tran ),( Tuan Duc Nguyen ),( Han Van Nguyen ),( Hanh Thuy Nguyen ),( Jong Oh Kim ),( Chul Soon Yong ),( Chien Ngoc Nguyen ) 영남대학교 약품개발연구소 2016 영남대학교 약품개발연구소 연구업적집 Vol.26 No.-

Polyro.t-lactic-co-glycolic acid) (PLGA) nanoparticles with negative surface charge were reversed to positive by cationic surfactant-DDAB before being coated with an anionic polymer, hyaluronic acid, to improve their site-specific intracellular delivery against CD44 receptor overexpressing cancer cells. Incorporating artesunate (ART)-a promising anticancer drug into PLGA/HA nanoparticles, is expected not only to overcome its poor aqueous solubility and stability but also enhance the activities. The obtained particles were characterized by dynamic light scattering, zeta potential measurements, and transmission electron microscopy (TEM). Cancer cell internalization of the NPs was evaluated by flow cytometry and cytotoxicity of the NPs was tested by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide assay. PLGA/HA nanoparticles showed greater extent of cellular uptake to SCC-7 and MCF-7 cells, indicating their affinity with CD44 receptor-mediated endocytosis. Almost 60 % of ART was released into the outer media after 48 h. In vitro fluorescence sorting demonstrated that PLGA/HA had highly efficient targeting and accumulation into CD44 receptor overexpression cells. The significant reduction in cell viability as well as greater induction of apoptosis suggested a potential in anticancer therapy of ART loaded PLGA/HA.

Compressive Sensing Recovery of Natural Images Using Smooth Residual Error Regularization

Chien Van Trinh,Khanh Quoc Dinh,Viet Anh Nguyen,Younghyeon Park(박영현),Byeungwoo Jeon(전병우) 대한전자공학회 2014 전자공학회논문지 Vol.51 No.6

압축센싱은 성긴 (sparse) 신호에 대해 Nyquist rate 미만의 샘플링으로도 신호 획득이 가능하다는 것을 수학적으로 증명한 새로운 개념이다. 그동안 영상분야 압축센싱을 위한 수많은 복원 알고리즘들이 제안되어 왔으나, 낮은 측정률 하에서는 복원 화질 측면에서 아직 개선할 점이 많다. 일례로, 자연 영상의 압축센싱 복원 화질 향상을 위해, 영상과 관련한 사전 정보들로부터 정규화 식을 도출하여 복원에 적용해 볼 수 있을 것이다. 따라서, 본 논문에서는 Dantzig selector 및 평활 필터(가우시안필터 및 nonlocal 평균 필터)기반의 평활 잔차 오류 정규화 방법을 제안한다. 또한, 복원 영상의 객체 및 배경에서 발생하는 edge 정보를 우수하게 보전하는 것으로 알려진 Total variation 기반 최소화 알고리즘에 적용하여 복원 영상의 화질을 향상시키는 방법을 제안한다. 제안하는 구조는 잔차신호의 평활화를 활용한다는 측면에서 새로운 압축센싱 복원 방식이라고 할 수 있다. 실험 결과, 제안방법은 기존 방법들에 비해 객관적 및 주관적 화질 측면에서 더 높은 성능 향상을 보여주었으며, 특히 기존 Bayesian 압축센싱 복원 방식과 비교 시 최대 9.14 dB 성능이 향상되었다. Compressive Sensing (CS) is a new signal acquisition paradigm which enables sampling under Nyquist rate for a special kind of signal called sparse signal. There are plenty of CS recovery methods but their performance are still challenging, especially at a low sub-rate. For CS recovery of natural images, regularizations exploiting some prior information can be used in order to enhance CS performance. In this context, this paper addresses improving quality of reconstructed natural images based on Dantzig selector and smooth filters (i.e., Gaussian filter and nonlocal means filter) to generate a new regularization called smooth residual error regularization. Moreover, total variation has been proved for its success in preserving edge objects and boundary of reconstructed images. Therefore, effectiveness of the proposed regularization is verified by experimenting it using augmented Lagrangian total variation minimization. This framework is considered as a new CS recovery seeking smoothness in residual images. Experimental results demonstrate significant improvement of the proposed framework over some other CS recoveries both in subjective and objective qualities. In the best case, our algorithm gains up to 9.14 dB compared with the CS recovery using Bayesian framework.

Persistence of vaccine-induced antibodies to A/H5N1 at 30 months and 36 months after vaccination in Vietnam

Chien Vien Chinh,Viet Phu Quoc,Loc Huynh Tan,Duoc Nguyen Van,Thai Pham Quang,Be Le Van 한국역학회 2021 Epidemiology and Health Vol.43 No.-

OBJECTIVES: An A/H5N1 vaccine (IVACFLU-A/H5N1) was accepted for use in Vietnam; however, antibody persistence after vaccination has not been well characterized. We examined post-vaccination antibody persistence and related risk factors in individuals enrolled in the phase II IVACFLU-A/ H5N1 vaccine trial in Ninh Hoa, Vietnam, who received a 15-μg dose (2 injections 21 days apart). METHODS: We used a longitudinal study design to follow 86 participants, without a control group. The participants tested as anti-A/H5N1 immunoglobulin G seronegative at baseline and received both doses of the vaccine. Blood was drawn at 30 months and 36 months after the complete vaccination to assess antibody status. Antibody persistence status was compared by demographic characteristics and exposure risk factors using univariate logistic regression. RESULTS: In total, 84.9% and 52.3% of the population showed persistence of at least 1/10 of the A/H5N1 antibodies at 30 months and 36 months after IVACFLU-A/H5N1 vaccination, respectively. The odds of antibody persistence were higher in older people, but lower in people who had experienced flu-like symptoms in the past 18 months or between 2 visits. We recorded no differences between A/H5N1 antibody persistence and exposure risk factors, including having a poultry farm, coming into contact with poultry, and slaughtering and processing poultry. CONCLUSIONS: This study demonstrated noteworthy antibody persistence, indicated by the seroconversion rate and geometric mean titer at 30 months and 36 months after the IVACFLU-A/H5N1 vaccine. Further studies should investigate older people and those who experienced flu-like symptoms to determine a suitable time for a booster shot.

An efficient location-based pilot assignment in Cell-Free Massive MIMO

Nguyen Tien Hoa,Phan Lam Tung,Van Chien Trinh 한국통신학회 2023 ICT Express Vol.9 No.5

Cell-free Massive multiple-input multiple-output can offer many degrees of freedom for the high data rate and coverage probability. This network topology is one of the cutting-edge technologies potentially applied for next-generation wireless communications. In the canonical structure, however, each access point needs to accurately estimate the channel state information for the signal detection in the uplink and the precoding design in the downlink. Due to the finite lengths of coherence intervals, pilot contamination is one of the bottlenecks, reducing the data throughput of each user. We propose an efficient pilot assignment scheme called location-based pilot assignment (LPA) to overcome this limitation. It takes full advantage of the number of orthogonal pilot signals into account. The proposed algorithm divides the coverage area into smaller areas based on the number of users, where each area uses a subset of the pilot signals. Numerical results show that the proposed pilot assignment, LPA, offers good spectral efficiency to every users in the network with a tolerable computational complexity.