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혈액종양 환자의 중심정맥 카테터에 대한 헤파린 관류와 생리식염수 관류의 효과 비교
문초희,연보라,김현진,은방희,배영이 병원간호사회 2006 임상간호연구 Vol.11 No.2
Purpose: The purpose of this study was to compare the efficacy of heparin flushing and normal saline flushing in maintaining patency of central venous catheters(CVCs), and to investigate relative risk factors of CVCs' occlusion. Method: A total of 159 patients who had been inserted with CVCs were included in the department of hemato-oncology of S hospital. The heparin group consisted of 74 patients with 10u/ml diluted heparin flushing from 23 November 2004 to 15 January 2005, and the normal saline group consisted of 85 patients with 0.9% normal saline flushing from 19 January to 31 March of 2005. Result: The heparin group was significantly different from the normal saline group in CVCs' occlusion. The normal saline group offered a much longer survival duration of CVCs' patency than the heparin group. Potential bleeding signs (PT, aPTT) had no significant differences. In multivariate analysis, 0.9% normal saline (hazard ratio 0.50), chemo port (hazard ratio 3.38), and no administration of TPN (hazard ratio 0.25) were the significant factors for occlusion of CVCs. Conclusion: For maintaining the patency of CVCs, 0.9% normal saline flushing are expected to be effective in reducing drug incompatibilities, lessening the bleeding tendency and improving cost effectiveness .
김은혜,최보문,유태열,백인호 大韓神經精神醫學會 1988 신경정신의학 Vol.27 No.4
Three cases of rapid cycling affective disorders were examined from a clinical perspective. We presented several different etiologies to the rapid cycling pattern in these patients. It was revealed that the rapid mood swings were due to natural expression of the affective disorder, tricyclic induced, lithium induced, and a combination of the aforementioned etiologies. Brief reviews on factors considered to induce rapid cycling, its etiopathogensis, clinical features and treatment strategies were also presented.
최보문,김종은 大韓神經精神醫學會 1990 신경정신의학 Vol.29 No.4
Since the reports on the effect of stimulants in controlling motor restlessness, inattention and distractibility, efforts have been made to elucidate the mechanism of action of the stimulants, and pathophysiology of the attention deficit hyperactivity disorder. This review has attempted to summarize biological findings on attention deficit hyperactivity disorder, from the fields of neuropharmacology and neuroanatomy. Most of the studies demonstrated that catecholamine function and its modulation are very probably involved at some level in the pathogenesis and treatment of this disorder. Reports on several neuroanatomical lesions also have implications for the catelcholamine hypothesis of the disorder. Further studies focusing on the response to stimulants and physiological studies using brain imaging technology will provide more comprehensive model of the pathophysiology of the attention deficit hyperactivity disorder.
구성태,송문영,강정묵,김용명,박보라,이은석,홍정아,김경식,손인철 한국전통의학연구소 2003 한국전통의학지 Vol.13 No.1
Literally, the mean of Tae-gye is highest brook. And on the basis of the acupuncture theory, Tae-gye point is the Soo earth point and source point of the Kidney Channel as well. In addition, Tae-gye point is one of the Yang-Returning Nine points. We were trying to study bibliographically on the Tae-gye point because Tae-gye point can be used very broadly across the symptoms in the theoretical aspect described above. As a results, we found out that according to the classical books of acupuncture, Tae-gye point is entering point of the Meridian Water as a source point and can be used at both Kidney-Sufficient Syndrom and Kidney-Deficient Syndrom. And Tae-gye can be applied to the disease of kidney or bladder that is urogenital symtoms, Also, Tae-gye is an useful option of tooth-ache, asthma, indigestion, constipation, edema etc whose cause is related with decrease of Kidney ki.
항정신병약물을 처음으로 사용하는 초발 정신증 환자에서 나타나는 체중 및 대사성 지표의 변화 : 후향적 연구
김우진,심주철,공보금,강제욱,문정준,김정은,김민걸,박민경,김성진,김현정,정도운 대한생물치료정신의학회 2011 생물치료정신의학 Vol.17 No.2
Objectives:This study was to identify weight & metabolic changes in first-episode psychotic patients with antipsychotics use and investigate the differences of weight & metabolic changes between first-episode psychotic patients and controls with antipsychotics use. Method:In this retrospective study, twenty eight first-episode psychotic patients and twenty eight controls with schizophrenia, schizoaffective or bipolar disorder defined by DSM-IV criteria were included. Information about demographic and clinical characteristics of the subjects was gathered from the medical records. Also body weight, sBP, dBP, fasting glucose, lipid profile and WBC count were evaluated before and after antipsychotics use. Rogistic regression was conducted to assess factors associated with weight gain. Results:First-episode psychotic patients showed more weight and BMI changes than controls after antipsychotics use, and these changes continue over 12 months. On the other hand, there were no significant factors associated with weight gain. Conclusion:The results of present study suggest that antispychotics is one of the major causes inducing weight gain of psychotic patients and antipsychotics-induced weight gain is more vulnerable to drug-naive first-episode psychotic patients.
문보경 ( Bo Kyung Moon ),김은아 ( Eun Ah Kim ),박미성 ( Mi Sung Park ),이동곤 ( Dong Kon Lee ),이미선 ( Mi Sun Lee ),최보라 ( Bo Ra Choi ) 중앙대학교 생활문화산업연구소 [ 구-생활과학연구소] 2007 생활과학논집 Vol.26 No.-
The purpose of this study was to make nutritious cookies with black rice powder and investigate the effects of the black rice powder on the quality of cookies. Black rice powder was added in the paste for the cookies discriminating the ratio of substitution; 0%, 20%, 40%, 60% of wheat flour. For analyzing quality characteristics density and pH of the paste, spread factors and texture of cookies were measured. The density and pH of the paste with black rice powders were higher than those of control group and gumminess and brittleness of cookies with black rice powder were lower than control group. In the sensory evaluation, cookies with black rice powder showed significantly higher scores in texture than control group and the one added 60% black rice powder showed the highest score. In colors, aroma, flavors and overall acceptability, cookies with black rice powder showed significantly higher scores than control group.
태내의 대기 중 휘발성유기화합물질 노출과 영유아시기 신경인지행동발달의 관련성연구 : 모자환경보건센터 (MOCEH)의 임산부 및 영유아 코호트연구
장문희(Moon-Hee Chang),하은희(Eun-Hee Ha),박혜숙(Hyesook Park),하미나(Mina Ha),김양호(Yangho Kim),홍윤철(Yun-Chul Hong),김붕년(Boong-Nnyun Kim),이보은(Bo-Eun Lee),서주희(Ju-Hee Seo),김병미(Byung-Mi Kim),박은교(Eun-kyo Park) 한국환경독성학회 2011 한국독성학회 심포지움 및 학술발표회 Vol.2011 No.10