원위 대퇴골의 고립성 골연골종에서 발생한 속발성 연골 육종 1례 보고

정필현,황장수,강석,김용민,오형호,채동주,김종필 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

연골육종은 비교적 서서히 자라며 늦게 전이하는 악성 연골 종양으로 알려져 있다. 골 연골종에서 발생한 속발성 연골육종은 발생빈도는 드물며 타부위로의 전이가 적고 악성도가 낮은 경우가 많아 적합한 수술적 치료로서 좋은 예후를 보이는 것으로 보고되고 있다. 본 동국대학교 정형외과학 교실에서는 우측 대퇴골 원위부 골간단부에 생긴 고립성 골 연골종에서 이차적으로 발생한 연골육종을 치험한 바 문헌고찰과 함께 보고하는 바이다. A case of Secondary Chondrosarcoma Arising from Solitary Osteochondroma of the Distal Femur Department of Orthopaedic Surgery, College of Medicine, DongGuk University Phil Hyun Chung M.D., Jung Su Hwang M.D., Suk Kang M.D., Yang Mln Kim M.D., Hyung Ho Oh M.D., Dong Ju Chae M.D., Jong Pil Kim M.D. Chondrpsarcoma is a malignant cartilage-forming tumor that grows slowly and metastasis of this tumor occurs in late stage. Secondary chondrosarcomas arising from a solitary osteocartilaginous exostosis are rare and those have a better prognosis than other chondrosarcomas, and they rarely metastasize. We present our experience with a case of secondary chondrpsarcoma arising in solitary osteochondroma of distal metaphysis of right femur with clinical details.

폐도자기로부터 제조된 재활용 소지의 소결특성

황규홍,한현근,김상우,이종국 조선대학교 생산기술연구소 2007 生産技術硏究 Vol.29 No.1

As increasing the porcelain as a home ware, the amount of waste porcelain is increased in factory or at home every year. It is very important to recycle the waste porcelain from environmental and economic point if views. Recycling of porcelain body to batch composition can be reduced the manufacturing cost of porcelain by production of raw materials and dropping of sintering temperature about 150~200℃. In this study, we prepared porcelain ceramics by mixing recycled waste ceramic raw materials and normal ceramic raw materials. The waste ceramic raw materials were recycled by crushing and ball milling waste porcelain bodies. The recycled ceramic raw materials after milling have a mean particle size about 22-40 ㎛ with irregular shape and narrow particle size distribution. Shrinkage and sintered density of compacts from recycled ceramic batch composition increased with increasing sintering temperatures, however the sintered density was independent on the amount of the recycled ceramic raw materials. The batch composition containing 30% of recycled ceramic raw materials showed the highest sintered density. Sintered density was decreased over the temperature of 1200℃ due to the creation of cracks on surface and in bulk. It may be concluded that sintering temperature can be reduced in the processing of porcelain body by adding of recycled ceramic raw matehals to normal batch composition.

Shelf Life Extension of the Cultured Wild Ginseng Pretreated with Sterilizer and Antimicrobial Mixture

황종현 忠州大學校 2009 한국교통대학교 논문집 Vol.44 No.-

Physicochemical and microbial changes were investigated for the shelf‐life extension of tissue cultured wild ginseng (TC‐wild ginseng) during storage using glass bottle and polyethylene (PE)‐pouch package at various temperature. The harvested TC‐wild ginseng showed greatly changes of pH , reducing sugar and moisture contents during storage at 20 and 30℃. However, the changes of them at 10℃ were not so great. Especially, the reducing sugar contents of them showed a slightly changes in bottle package, but showed a greatly differences in PE‐pouch package during storage at 20 and 30℃. pH, reducing sugar and amino nitrogen contents also increased with increasing storage time. In PE‐pouch package, The browning index “a/b” increased 0.131 to 0.441, 0.472 and 0.498 at 10, 20 and 30℃ after 14 days, respectively. The deterioration of TC‐wild ginseng is generally associated with browning and changes of components. Consequently, The treatments with antimicrobial agents were carried out and assessed the storage stabilities at 10℃ because of great changes in pH, reducing sugar and amino nitrogen contents at 20 and 30℃. The treatment like blanching or antimicrobial agents were carried out for the purpose of microbial inhibition during storage. Comparing with browning index of TC‐wild ginseng and that of TC‐wild ginseng treated with CAMICA‐SD, browning index of the former and latter were 0.404 and 0.300 on 14th day at 10℃, respectively. Also, microbial growth between TC‐wild ginseng and TC‐wild ginseng treated with antimicrobial agents were investigated during storage at 10℃. After treatment of antimicrobial agent, total viable cell numbers of TC‐wild ginseng were remarkably retarded than that of non‐treated TC‐wild ginseng.

좌심실비후 환자에서 베타차단제의 급중단이 임상증상 및 좌심기능에 미치는 영향

황종현,김영태,배용학,임현주,조용근,채성철,전재은,박의현 慶北大學校 醫科大學 1997 慶北醫大誌 Vol.38 No.1

목적 : 베타 차단제와 칼슘 길항제의 장기투여로 안정상태에 있는 비후형 심근증이나 고혈압성좌심실비후 환자에서 이들 약제를 갑자기 중단하였을 때 혈역학, 심기능 및 임상상에 미치는 영향을 알아보기 위하여 본 연구를 시행하였다. 대상 및 방법 : 경북대학교 병원 순환기내과에서 통원치료중인 비후형 심근중 환자 5명과 심한좌심실비후를 동반한 고혈압 환자 6명(남자 6명, 여자 5명)을 대상으로 장기투여 중이던 베타 차단제와 칼슘 길항제를 최소 5일 중단한 후 임상증상, 혈압 및 심박수의 변동, 그리고 투약중지 전후에 도플러 심초음파도를 기록하여 좌심실내경, 벽두께, 좌심실근량, 구혈율 및 승모판혈류속도곡선의 변화를 관찰하였다. 결과 : 1) 약물치료 중단 후, 베타차단제의 경우 9명 중 6명에서, 그리고 칼슘길항제 및 디소피라미드를 복용하던 각 1명, 도합 7명의 환자에서 심계항진, 호흡곤란의 악화, 흉통이 관찰되었고, 심계항진을 호소한 1예에서는 심방세동이 재발되었다. 2) 혈압, 심박수, 확장말기 및 수축말기 좌심실내경, 심실중격 및 심실후벽 두께, 좌심실근량 및 구혈을 모두는 치료약물 중단 전후에 다소 변화하였으나 유의하지 않았다. 3) E파 최고속도와 E파 시간속도적분은 약물투여 중단 전후에 유의한 변화는 없었으나, A파 최고속도와 A파 시간속도적분은 중단 후에 각각 유의하게 증가하였으며(both P<0.01), E/A 최고속도비와 E/A 시간속도적분비는 각각 유의하게 감소하였다(both P<0.01). 한편, E파 감속시간, 등용이완시간 그리고 A-Ar 간격[A파의 최고점에서 A reversal(Ar)파의 최저점간의 시간] 모두는 중단 후 유의한 변화가 없었다. 1 결론 : 비후형 심근증 이나 고혈압성 좌심실비후 환자에서 장기투여중이던 베타 차단제와 칼슘길항제를 일시적으로 중단하였을 때 임상중상의 악화와 더불어 확장기 기능의 변화를 초래하였다. 따라서 약물치료로 비록 임상적으로 안정상태에 있더라도 치료를 갑자기 중단할 때는 주의해야 할 것으로 생각된다. Objectives : This study was done to evaluate the changes in clinical findings, hemodynamics and cardiac function after abrupt withdrawal of longterm beta-blockers and/or calcium channel blockers in hemodynamically stable patients with hypertrophic cardiomyopathy and left ventricular(LV) hypertrophy associated with hypertension. Methods : Eleven patients with hypertrophic cardiomyopathy(n=5) and LV hypertrophy associated with hypertension(n=6) were studied. Symptom assessment, blood pressure, electrocardiography and echocardiography including pulsed Doppler examination were obtained before and at least 5 days after abrupt cessation of beta-blockers and calcium antagonists. Results : 1) Deterioration in symptoms(i.e. palpitation, aggravation of dyspnea and chest pain) was observed in seven patients after abrupt withdrawal. 2) There were no significant changes in blood pressure, heart rate, end-systolic and end-diastolic LV dimensions, interventricular septal thickness, LV posterior wall thickness, LV mass, and ejection fraction before and after drug withdrawal. 3) Doppler time intervals and E wave peak-velocity and time velocity integral(TVI) were not significantly changed before and after drug withdrawal. But A wave peak-velocity and TVI after abrupt withdrawal were significantly increased(both p<0.01), and E/A peak-velocity ratio and TVI ratio were significantly decreased(both p<0.01). Conclusions : These findings suggest that temporary omission of beta blockers and calcium channel blockers develops deterioration in symptoms and LV diastolic dysfunction in hypertrophic cardiomyopathy and LV hypertrophy associated with hypertension. Physicians should avoid abrupt withdrawal of longterm beta blockers in LV hypertrophy.

상시계측자료의 관리를 위한 테이터베이스의 원형 설계

황진하,박종희,조대현 충북대학교 건설기술연구소 2003 建設技術論文集 Vol.22 No.2

Prototype design of the database for ambient measurement data management is presented in this paper. To express the associated data generated during the whole process of ambient measurement efficiently, requirement/task analysis for database management system are peformed. And then to define and organize objects and schema for data model, conceptual and logical design are performed, which convert data model into logical schema. This prototype database is constructed by using via the object-relational data modelling approach.

두가지 혈류 유발방법에 의한 새로운 심폐소생술(이중 혈류 유발 심폐소생술)장치의 개발

황성오,김현,조준휘,오범진,임종천,최경훈,윤정한,이승환,김영식,이강현,이윤선 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.2

Background: There have been many efforts to augment blood flow during cardiopulmonary resuscitation. These efforts have focused on maximizing the effect of cardiac pump or thoracic pump alone. However, considering that the heart is the biggest blood reservoir and increase of intrathoracic pressure can generate blood flow, simultaneous exploitation of both mechanisms may have synergistic effect. We hypothesized that simultaneous chest constriction in addition to sternal compression by standard CPR may have additive hemodynamic effects by preventing deformation of the chest and increase of intrathoracic pressure. Methods and results: we built a new mechanical device to perform compression and thoracic constriction simultaneously. The device consists of two main elements. Piston in the center is to depress the sternum. Strap is to constrict the thorax circumferentially. Strap is attached to both sides of the piston. When the piston is pushed down, it depresses the sternum and pulls on the thoracic strap. To determine strap width to produce optimal hemodynamic effect, we measured hemodynamic parameters with variable widths of strap in two dogs after induction of ventricular fibrillation. Result of the experiment showed that 10cm wide strap was determined to be most effective. We also determined optimal depth of compression to produce maximal hemodynamic effect with animal experiments using two dogs. Animal experiments showed that the highest aortic pressure could be generated when the stemum was depressed to 5 cm. Cardiopulmonary resusciation using a new device could generate higher systolic aortic pressure, coronary perfusion pressure and end-tidal carbon dioxide tension in comparison with standard cardiopulmonary resuscitation in a pilot animal study using two dogs. Conclusion: New cardiopulmonary resuscitation method using a mechanical device designed by us could perform sternal compression and simultaneous thoracic constriction, and generate better hemodynamic effects than standard cardiopulmonary resuscitation in pilot animal experiments.

신기능성 물질 탐색을 위한 침엽수잎의 특수성분 분석에 관한 연구 (Ⅰ) : 펙틴, 탄닌, 테르페노이드의 분석 Analysis of Pectin, Tannin and Terpenoids

황병호,이현종,강하영,유순희,조재현,조국란 江原大學校 森林科學硏究所 1997 Journal of Forest Science Vol.13 No.-

요 약 주요 소나무류잎의 특수성분을 분석하여 시판되고 있는 솔잎 가공식품의 기초데이터를 제공함과 동시에 임산화학 분야의 학문적 기초데이터를 축적하기 위하여 실시한 결과, 펙틴은 잣나무가 가장 높게 분석되었으며, 탄닌은 잣나무가 높게 분석되었고, 소나무와 해송은 유사하였다. 테르페노이드 성분중 α-pinene은 소나무와 잣나무에서, β-pinene은 리기다와 해송에서 높게 분석되었으며, 희귀성분으로는 잣나무에서 sabinene과 citronellol, 리기다에서는 α-pinene oxide 등이 분석되었다. 특히 소나무일체 다량 존재하는 성분은 α-pinene, β-caryophyllene, β-phellandrene, Δ3-carene, phytol 등 이었다. 향기성분의 주체인 α-pinene, limonene, bornylacetate들이 소나무와 잣나무에서 보다 많이 분석된 것으로 보아 삼림욕의 상쾌한 내용의 주체성분이라고 생각된다. ABSTRACT Pectin and tannin analysis were carried out to inverstigate any available components from Pinus densiflora, koraiensis, P. thunbergii and P. rigida. To analyze terpenoid components, the essential oils were extracted with steam distillation method from four kinds of pine needles. The essential oil was analyzed by GC and GC-MS spectroscopy.The results were summarized as follows: Pectin content was highest in P. koraiensis with 0.40%, and tannin content was highest in P koraiensis with 1.05. Major components of P. densiflora needles were α-pinene, β-caryophyllene, Δ3-carene and phytol. α-Pinene, Δ3-carene, β-caryophyllene, germacrene D, and camphene were found major components n P. koraiensis. Major components of P. thunbergii needles were β-pinene, α-pinene, β-caryophyllene and germacrene D. β-Pinene, α-pinene, humulene oxide and α-elemene were major components in P. rigida. Sabinene and citronellol were infrequent components in P. Koraiensis, and α-pinene oxide was present only in P. rigida. α-Pinene, limonene, and bornylacetate well known as the mail components of green air bath were found in P. densiflora and P. koraiensis.

高度産業社會에서의 都市와 農村의 連繫性 强化方案

黃明水,李顯鍾 단국대학교 산업연구소 1980 산업연구 Vol.2 No.-

Kawasaki병의 임상적 고찰

황종원,허재원,정현기 고신대학교 의학부 1997 高神大學校 醫學部 論文集 Vol.12 No.1-2

Purpose : This study was designed for clinical manifestations, laboratory findings, onset of coronary artery lesion and disease process after the high dose IVGG therapy in Kawasaki disease. Methods : Fourty-four cases with Kawasaki disease who were diagnosed and treated at the Department of Pediatrics, Kosin University Hospital from January 1993 to April 1996,were investigated for their clinical manifestations and laboratory findings, and cardiac complications. Results : (1) In age distribution, the most prevalent age group was under the age of 4(81.9%) and the mean age was 2.71±1.8 years old. (2) Boys were more prevalent than girls, as a ratio of 2.1: 1. (3) Principal clinical features were high fever developed in 100% and lasted for 6.9±3.8 days, polymorphous exanthem in 84.1%, conjunctival injection in 93.2%, oral cavity lesion in 90.9 %, cervical lymphadenopathy in 59 %, indurative edema of hands and feet in 63.6 %, desquamation in 59%. (4) Main laboratory findings were anemia 22.7 %, leukocytosis 93.2 %, thrombocytosis 81.8 %, increased ESR 93.2 %, positive CRP 100%, increased SGOT 19 %, increased SGPT 30.9 %, pyuria 57.8%, proteinuria 7.9 %, microscopic hematuria 7.9 %, and abnormalities of EKG 18.1 %. (5) Abnormal findings of the heart were found in 40.9 % by echocardiogram, the abnormality of coronary artery were present in 15.9 % (which were coronary artery aneurysm 9.1 % and coronary artery dilatation 6.8% 1, pericardial effusion 11.3% and moderate degree of mitral and tricuspid regurgitation 13.6 % . (6) 3 cases of coronary artery aneurysm were occurred in the IVGG 400mg/kg/day for 5 days group, 1 case of coronary artery aneurysm and 3 cases of coronary artery dilatation were found in the IVGG lg/kg/day for 2 days group. (7) The follow-up echocardiogram, 2 months later of IVGG administration, the result were as follows : ① Among 2 cases of mild coronary artery aneurysm, one was disappeared and the other was not followed. ② 2 cases of giant coronary artery aneurysm were not improved. ③ All cases of coronary artery dilatation and pericardial effusion were disappered. ④ Among 6 cases of moderate degree mitral and tricuspid regurgitation, 5 cases were improved and other 1 case was improved from grade 3/4 to grade 2/4. Conclusions : We concluded that early combination therapy with high dose IVGG and aspirin is effective for prevention of coronary artery aneurysm development and for treatment of acute inflammation in Kawasaki disease.

전기 화상 환자의 수술 전 평가,고압손상과 저압손상 비교

황정원,이정기,전영태,강종만,오용석,노규정,김현철 대한정맥마취학회 2004 정맥마취 Vol.8 No.1