경부도상 피판을 이용한 구강내 결손부의 재건

양동규,신상훈,서종천,이성근,김종렬 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.3

Various cutaneous as well as myocutaneous flaps have been designed for the reconstruction of tissue defects caused by the excision of oral cancer. Among these flaps, cervical island skin flap have been introduced by Farr et al and more have developed by Tashiro et al. This flap has many advantages. The flap minimizes donor size by use of cervical operation wound, flap size available is adequate for most oral defects and the procedure is relatively simple and time saving. However, this flap is not applicable in patients where there are large tissue defects and metastasis is suspected. We used this flap for it's rapid simple, and effective, primary closure of oral defects after cancer ablation and we have found this flap very useful for the reconstruction of relatively small oral defects.

석곡광산(石谷鑛山) 부근의 지질과 광화작용(鑛化作用)에 대하여

梁承榮,李倫鐘 慶北大學校 師範大學 1972 敎育硏究誌 Vol.14 No.-

The Seokgok Mine area, which is located in Dong-myun, Jungseon-gun, Kangwon-do, is composed of Pungchon limestone formation, Hwajeol formation, Dongjeom quartzite formation, Dumudong formation and Magdong limestone formation in ascending order, which are included in the so-called Great limestone Series, Cambro-Ordovician in age. The ore deposit is developed partially along the fracture in the Pungchon limestone formation. And its origin is considered as a filling replaced type. The shape of the ore body is very irregular and in which remains the non-replaced limestone relicts. Ore minerals are mainly galena, sphalerite, pyrite and chalcopyrite, which are associated with small amount of other sulfide minerals.

In vitro propagation of Coleus forskohlii, an important medicinal plant

Yang,Deok-hun,Jeon,Manju-Meluttu-George,Jong-Seong 한국자원식물학회 2003 Plant Resources Vol.6 No.2

For mass multiplication of an important medicinal plant Coleus forskohlii, a procedure for the high frequency regeneration of Coleus forskohlii has been developed using leaf explants via callus culture. Callus formation occurred in MS medium supplemented with 1-2 mg/L each of NAA and BAP. A large number of shoots were formed on MS + 1 mg/L BAP from 50-60 days old greenish calli. Rooting of healthy shoots occurred on 0.1-0.4 mg/L NAA. The protocol described could be useful in future for genetic manipulation of this plant species.

TOOL LIFE를 고려한 다기능 기계의 SCHEDULING에 관한 연구

양성민,이종문 慶星大學校 1993 論文集 Vol.14 No.2

Scheduling is very important problem in managing any system in anywhere. In recent years Factory Automation is accomplished by accepting the multi-functional machines. So obtaining the optimal scheduling solution is very difficult. and if the considering factors are increased, the optimal scheduling is more difficult. So in this study proposes the convenient heurisic algoritm considered machine utilization, mean flow time of each product and tool life of each machine.

고상-기상 반응에 의한 질화 알루미늄 휘스커 합성

강종봉,양성구,이성우,정승화 慶南大學校 附設 工業技術硏究所 2003 硏究論文集 Vol.21 No.2

질화알루미늄 휘스커 합성을 위하여, Al원으로는 Al_2O_3, Al(OH)_3, AlOOH를 사용하였고, 환원제로는 카본블랙, 기상반응을 유도하기 위하여 AlF_3, NH_4F, CaF_2를 사용하여 고순도 질소분위기에서 실험을 행하였다. 또한 액상반응 시 미세구조상의 변화를 확인하기 위하여 금속 알루미늄을 첨가하여 실험을 행하였다. 질화알루미늄의 생성과 침상형 휘스커상의 형상은 1600℃의 온도에서 가장 잘 나타났으며 열처리 온도의 상승은 오히려 휘스커상의 형성을 방해하고 있음을 보여주었다. 침상형 휘스커의 합성에 가장 큰 영향을 주는 것은 기상반응을 일으키는 AlF_3 첨가이며, AlF_3 첨가량이 증가함에 따라 침상형 휘스커상의 증가를 확인할 수 있었다. 액상 반응을 위한 금속 알루미늄 첨가는 전체의 15 wt%까지는 침상형 휘스커가 증가하였으나 15 wt%이상으로 첨가하는 경우 오히려 침상형 휘스커가 감소하는 것으로 나타났다. To synthesize aluminium nitride whisker, Al_2O_3, Al(OH)_3, and AlOOH were used for aluminium element. Experiment was done under the high purity nitrogen atmosphere with carbon black as deoxidation agent and AlF_3, NH_4F and CaF as gas phase reactants. Metallic aluminium was used for liquid phase reaction in which microstructural change occured. The AlN with whiskered Phase was formed at 1600℃ and the increase of temperature inhibited the formation of whiskered phase. AlF_3 was the main factor for the formation of needle-shaped whiskers, and the amount of whisker increased with AlF_3 contents. The amount of needle-shaped AlN whiskers increased with the addition of metallic aluminium up to 15 wt% but decreased with aluminium of above 15 wt%.

Shaphylococcus enterotoxin B와 lipopolysaccharide를 작용시킨 사람 섬유아 세포에서 생성된 Transforming Growth Factor-β₁의 정량적 분석

이성근,김광혁,김욱규,김종렬,정인교,양동규 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.2

TGF-β1 is a potent chemotactic factor for inflammatory cells and fibroblasts. It also stimulates the celluar source and components of extracellular matrix and the production of proteinase inhibitors. Collectively, these biologic activities lead to the accumulation and stabilization of the nascent matrix, which is vital to infection control. The objective of this study is to investigate production of TGF-β in vitro fibroblast culture in the presence of Staphylococcus enterotoxin B(SEB) and/or lipopolysaccharide(LPS) and to elucidate the role of TGF-β1 which may be responsible for infection control. The fibroblasts were originated from gingiva and facial dermis in 26 year-old male patient. In the presence of LPS(0.01㎍, 0.1㎍, 1.0㎍), SEB(0.01㎍, 0.l㎍, 1.0㎍) respectively, cells(5×103ml) were cultivated in vitro. At 1, 3, and 5 days after incubation, cells were counted. Also, cells(2.5×105ml) were cultivated in EMEM with LPS(0.01, 0.1 and 1.0㎍), SEB(0.01, 0.1 and 1.0㎍) respectively and LPS(0.1㎍) and SEB (0.1㎍) in combination for 24,48, and 72 hours respectively. Culture supernatants were harvested at 1, 2, and 3 days after incubation period and triplicate culture supernatants were pooled and TGF-β1 was assayed in duplicate. The results were as follows. 1.In gingival fibroblast induced with SEB and LPS respectively or in combination, the suppression of cell Proliferation occurred very significantly since 3 days after incubation, compared with the control and the production of TGF-β1 occurred very significantly at 1 day after incubation, compared with the control. 2.In facial dermal fibroblast induced with SEB and LPS respectively or in combination. the suppression of cell proliferation occurred very significantly at 1 day after incubation, compared with the control. In SEB exposure, the production of TGF-β1 was decreased very significantly at 1 day after incubation, compared with the control. However, in LPS, SEB and LPS exposure, the production of TGF-β1 was increased very significantly at 1 day after incubation, compared with the control. In conclusion, the concentration of bacterial toxins and the incubation period correlated with cell proliferation and production of TGF-β1 very significantly. The gingival and facial dermal fibroblasts have different phenotype each other The orchestrated understanding of fibroblast proliferation and TGF-β1 production play an important part in host defense against the bacterial Infection and may prevent tissue necrosis such as necrotizing fasciitis and life-threatening syndrome such as multiple organ failure.

인슐린 비의존형 당뇨병 환자에서 혈장 Endothelin-1농도의 변화

신양수,조희충,김원식,국기용,김용화,정종훈,문철웅,배학연,양성훈 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.2

Endothelin(ET) is a 21-residue peptide originally isolated from the cultured porcine endothelial cells. There are at least three genes for endothelin:endothelin-1(ET-1), endothelin-2(ET-2), and endothelin-3(ET-3). Endothelins are present in various human biological fluids including plasma, urine, breast milk, and saliva and have been found elevated plasma ET concentrations in patients with diabetes mellitus, Patients undergoing maintenance hemodialysis due to chronic renal failure, patients with acute myocardial infarction, and patients with subarachnoid hemorrhage. Endothelial cell damage is suspected to occur in diabetic patients and may be one important cause of angiopathy, a major complication in diabetes mellitus. The elevation of ET in diabetic patients may be a marker of, and further exacerbate, their vascular disease. We measured the levels of ET-1 in plasma of 50 patients with non-insulin dependent diabetes mellitus(NIDDM) and 25 normal subjects by radioimmunoassay. The plasma ET-1 concentration (mean±S.D.) in NIDDM was 6.461 A2.510 f㏖/ ㎖, and was significantly higher than in normal subjects (4.567±1.155f㏖/㎖) (P<0.05). The plasma ET-1 concentration (mean±S.D.) in diabetic retinopathy group( 7.15±2.454 f㏖/ml) was significantly elevated than those in otherwise uncomplicated groups (5.348±2.390 f㏖/㎖)(P<0.01). The correlation between any clinical parameters and plasma ET-1 levels in NIDDM was not significant, In conclusion, this study suggest that the elevated levels of ET-1 in diabetic patients may be play a important role in the pathogenesis of diabetic complications.

현행 중학교 과학 실험·실습교육에 대한 교사들의 견해와 개선방안

이윤종,기우항,김영호,정원우,양승영,강용희,안병호,임성규,윤일희,김중욱,강동진 경북대학교 과학교육연구소 1996 科學敎育硏究誌 Vol.20 No.-

The status of facilities, management of the experiment, practices, and Science education teaching method in middle school have been investigated. The present status and reasonable management of middle school science education have been grasped from the questionaires. The results are as follows : The reasonable management for expeiments and practices of science education were scanty in the middle school around the urban and rural schools owing to the shortage of facilities and equipments, crowded class, excessive classes, work for teachers, excessive contents of present textbook and insufficience of administrative support etc. The current teaching method of middle school science has emphasized knowledge. This fact does not satisfy the objective of learning due to lack of teaching method. Desirable directions for the improvement of present status of middle school science education were proposed in this paper.

강모단 하방에 용수철이 부착된 칫솔의 치태 제거 효과에 관한 임상적 연구

조성훈,양규호,오종석 전남대학교 치과대학 2000 전남치대논문집 Vol.12 No.1

Oral examinations were conducted before the experiment started. The students were given common toothbrushes (control group) or spring-attached toothbrushes (experimental group) and instructed to brush their teeth by scrubbing method. Measurement of plaque index and count of salivary bacteria were done at 0, 1, 3, and 5 weeks. 1. Mean plaque index was significantly reduced at week 1 compared with at week 0 in both groups. (P<0.05) 2. Mean plaque index was significantly reduced at week 3 compared with at week 1 in the experimental group. (P<0.05) 3. Mean plaque index was significantly reduced at week 5 compared with at week 3 in the experimental group. (P<0.05) 4. There were no significant differences of mean plaque index among week 1, week 3, and week 5 in control group. (P>0.05) 5. The number of salivary bacteria was slightly reduced during the experiment, however there was no statistical significance. (P>0.05) To reduce the plaque effectively, the use of spring-attached toothbrush should be recommended, and adequeate instruction for children is needed.

흡연에 의한 급성 호산구성 폐렴 2예

박종빈,김학렬,주현준,유태양,신성남,신정현,송정섭,황기은,김소영,양세훈,정은택 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

최근 흡연을 시작한 젊은 성언에서 급성 호산구성 폐렴의 발생에 대한 증례가 보고되고 있다. 급성 호산구성 폐렴은 대개 발열을 동반하기 때문에 초기에는 감염성 폐렴으로 잘못 진단, 치료되는 경우가 많다. 아직 정확한 병태 생리 및 조직학적 소견은 밝혀져 있지 않지만 병력 청취 및 임상 양상, 방사선 소견의 관찰을 통해 급성 호산구성 폐렴을 의심하고, 진단을 위해 기관지 폐포 세척액 검사를 시행한다면 좀 더 쉽게 진단 내릴 수 있을 것이다. 본 저자들은 최근 처음 시작한 흡연에 의해 발생한 급성 호산구성 폐렴을 진단하고, 스테로이드를 투여하여 성공적으로 치료한 환자 2예를 경험하였기에 이를 문헌 고찰과 함께 보고하는 바이다. Acute eosinophilic pneumonia(AEP) is characterized by acute febrile respiratory illness associated with diffuse pulmonary infiltration and pulmonary eosinophilia. The specific etiology for acute eosinophilic pneumonia is elusive. By some investigators, cigarette smoking is suggested as a causative substance which can cause AEP. In recent, the authors experienced two cases of AEP following cigarette smoking. Both cases had characteristic features including age around 20 years, new onset smoking before occurance of AEP, diffuse infiltration on chest radiography, pulmonary eosinophilia based on bronchoalveolar lavage and acute improvement after steroid therapy. These clinical features are resemble with previous smoking induced AEP case reports. Base on these clinical features, cigarette smoking associated AEP could be diagnosed more easily.