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RISS 인기검색어
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- 저자 : 서종천 (검색결과 7 건)
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김태규,정기돈,신상훈,김성길,이성근,박상준,서종천 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.3
We performed costochondral grafting in mmandibular reconstruction including condyle replacement in 5 patients which have 4 cases of ameloblastoma, 1 case of resorption of left condyle due to osteomyelitis. We harvested the 6 th costochondral cartilage of unaffected side. No specific complications were appeared with unexpected fracture of costochondral junction and infection of operation site, These patients show 30-45mm at month opening, near normal of affected side, near normal or normal of unaffected side at lateral excursion. Postoperative coureses was uneventful with improved cosmetic and functional results. Our report is indicated that the costochondral graft is satisfactory to reconstruct mandibular defect including condyle replacement, especially in growing patients.
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구강편평세포암종에서의 Cisplatin 유도 아폽토시스에서의 NF-κB의 활성화
서종천(Jong-Chun Seo),성일용(Iel-Yong Sung),김종렬(Jong-Roul Kim) 대한구강악안면외과학회 2006 대한구강악안면외과학회지 Vol.32 No.2
Purpose: This study was done to confirm the role of NF-κB in cisplatin-induced apoptosis of oral squamous cell carcinoma. Materials and Methods: Five cell lines originated from different oral cancer patients were tested for the apoptosis by the treatment of cisplatin. These cells showed different degree of cisplatin-resistance and the order is OSCC-2〉 OSCC-3〉 OSCC-5〉 OSCC-1〉 OSCC-4. OSCC-2 and OSCC-4 cells were assayed for the apoptosis by measuring DNA fragmentation and TUNEL staining after cisplatin treatment. While OSCC-4 cells showed apoptosis, OSCC-2 cells showed no or very slight apoptosis by cisplatin treatment. Next, It was determined whether NF-κB activation is required in mediating cisplatin-induced apoptosis of OSCC-4 . Result: The result was that elevated NF-κB activity mediated cisplatin-induced apoptosis. Conclusion: In conclusion, these findings suggest that NF-κB activation is essential to cisplatin-induced apoptosis and it may be involved in cisplatin resistance in OSCC cells.
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서종천(Jong Cheon Seo),김종렬(Jong Ryoul Kim),양동규(Dong Kyu Yang) 대한구강악안면외과학회 1996 대한구강악안면외과학회지 Vol.22 No.1
This study was undertaken to investigate the changes of maximum bite force, range of mouth opening, and muscle activity in EMG after orthognathic surgery. The maximum bite force, range of mouth opening, and muscle activity in EMG were measured in 20 dentofacial deformity patients, aged 19-38(mean age 23.95) years, before surgery and at 2, 3 and 6 months after surgery. These patients were divided into three groups according to operation methods, that is 3 in IVRO group, 8 in BSSO group, and 7 in two-jaw surgery group. Thereafter the recovery of maximum bite force and the effect of duration of intermaxillary fixation were assessed. The results, were as follows. 1.The presurgical maximum bite force was 12.13 kg in upper first molar(Lt. Side 12.15kg, Rt. side 12.15kg respectively). being much lower than that of normal occusion, and maximum mouth opening was 48.45mm, falling in the normal range. 2. Maximum bite force and mouth opening were much increased 3 months after surgery in BSSO group and 3 months to 6 months after in IVRO and two-jaw surgery groups. 3. Muscle activity in EMG during maximal bite was lower than that of normal occlusion and approaching to the presurgical value or above at follow up examination 6 months after surgery. 4. It takes approximately 6 months after surgery for the bite force to recover to its presurgical value.
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인공판막 후부 공동부가 판막의 수력학적 성능에 미치는 영향
이계한,서종천 대한의용생체공학회 1998 의공학회지 Vol.19 No.3
판막 후부의 공동부는 판막의 닫힘 거동과 판막 주위의 혈류 유동장을 변화시켜 인공 판막의 수력학적 성능에 영향을 미칠 수 있다. 계식 이엽 판막(SJMV), 폴리머 단엽 판막(MLPV), 폴리머 삼엽 판막(FTPV)을 판막 후부에 공동부가 있는 시험부와 공동부가 없는 직관형 시험부에 설치하여 모의 순환 장치에서 판막의 수력학적 성능을 평가하였다. 판막의 누수량은 공동부가 있는 시험부에서 약간 작았고, 수축기 평균 압력강하는 크게 나타났으나 통계적으로는 큰 차이가 없었다. 따라서 판막 후부의 공동부는 판막의 수력학적 성능에 큰 영향을 나타내지 않았다. 유량 파형의 해석 결과 판막 후부 공동부는 MLPV에서는 판막의 닫힘에 큰 영향을 주지 않았으나, SJMV에서는 판막의 닫힘이 일찍 시작하게 하였고 이 영향은 FTPV에서 더욱 크게 나타났다. FTPV는 공동부가 있는 시험부에서 역류 최대 유량이 감소하였으므로 판막 후두에 공동부는 판막의 급격한 닫힘에 의한 역류 제트의 발생을 감소시키리라 기대된다. The sinus distal to the prosthetic heart valve influences the valve closure behavior and velocity field near the valve, therefore affects the hydrodynamic performance of the prosthetic heart valve. In order to study the effects of valve distal geometry on the hydrodynamic performance of the prosthetic valves, mechanical bileaflet valve(SJMV), monoleaflet polymer valve(MLPV) and trileaflet polymer valve(FTPV) are inserted in the test sections which have the straight and the sinus shape distal to the valve. Leakage volumes and systolic mean pressure drops are measured in the pulsatile mock circulation flow loop. Leakage volumes are slightly less and systolic mean pressure drops are higher in the sinus test section comparing to those in the straight test section, but the differences are statistically insignificant. Flow waveforms are analyzed in order to predict the valve closure behavior. The distal sinus does not affect the closure of the MLPV, but early valve closure of SJMV is observed in the sinus test section. This effect is more significant in FTPV, and the reverse flow peak of FTPV is reduced in the sinus test section. Therefore the sinus distal to the valve can reduce the reverse flow jet caused by sudden valve closure.
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양동규,신상훈,서종천,이성근,김종렬 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.3
Various cutaneous as well as myocutaneous flaps have been designed for the reconstruction of tissue defects caused by the excision of oral cancer. Among these flaps, cervical island skin flap have been introduced by Farr et al and more have developed by Tashiro et al. This flap has many advantages. The flap minimizes donor size by use of cervical operation wound, flap size available is adequate for most oral defects and the procedure is relatively simple and time saving. However, this flap is not applicable in patients where there are large tissue defects and metastasis is suspected. We used this flap for it's rapid simple, and effective, primary closure of oral defects after cancer ablation and we have found this flap very useful for the reconstruction of relatively small oral defects.
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경부도상피판을 이용한 구강내 결손부의 재건 - 13증례분석
김종렬,강영기,서종천,성일용 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.3
The celvical flap, comprising skin, fascia, and platysma muscle, has significant application in the head and neck region after radical ablative surgery for cancer of the oral cavity. The flap may be used for recon-struction of the cheek, floor of the mouth, and lateral side of the tongue. This flap minimizes donor morbidity by use of cervical operation wound and flap size available is adequate for most oral defects and the procedure is relatively simple and time-saving. However the flap is not applicable in patients where there are large tissue defects and metastasis is suspected. We have used the celvical flap for its rapid, simple, and effective closure of oral defects after cancer ablation and found it is very useful for the reconstruction of relatively small oral defects.
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