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한국여성에서 조직 미네랄 농도에 따른 생리전증후군의 임상증상
조현희 ( Hyun Hee Cho ),정인철 ( In Chul Jung ),정재은 ( Jae En Jung ),최세경 ( Sae Kyung Choi ),김수연 ( Su Yeun Kim ),김미란 ( Mee Ran Kim ),임용택 ( Yong Taek Lim ),김은중 ( En Jung Kim ),김진홍 ( Jin Hong Kim ) 대한산부인과학회 2008 Obstetrics & Gynecology Science Vol.51 No.1
목적: 생리전증후군이란, 황체 후반기에 특정한 정신적, 육체적 증상이 주기적으로 나타나는 질환을 말하며, 발생율은 80%에 이르나 원인은 명확하게 밝혀져 있지 않다. 프로게스테론과 에스트로겐이 체내 미네랄의 균형에 영향을 주기 때문에 생리전증후군 환자들에서 나타나는 프로게스테론의 감소와 에스트로겐이 우세 현상은 조직 내 미네랄의 균형에 이상을 초래할 수 있으며, 이로 인해 생리전증후군의 여러 특이 증상이 유발될 가능성이 있다. 이에 저자는 환자의 조직 미네랄 검사를 통해, 생리전증후군이 있는 환자에서 미네랄 수치와 증상과의 연관성을 알아보고자 본 연구를 시도하였다. 방법: 생리전증후군에 대한 모발검사 연구 지원자는 공고를 통해 모집된 여성을 대상으로 MMDQ 설문지를 작성하도록 하여 총점 10점 이상인 여성 120명으로 대상으로 하였다. 모발을 이용한 조직미네랄 검사는 최근 3주간 염색이나 파마를 하지 않고 3시간 이내에 세정이나 모발관련 제품을 사용하지 않은 상태에서 시행되었으며, 미국 TEI에 분석을 의뢰하였다. 통계분석은 SPSS (Ver. 14.0)를 사용하였다. 결과: 조직 내 마그네슘 농도가 정상인 군의 MMDQ 총점은 비정상인 군보다 유의하게 높았으며 (22.5±17.8 vs. 13.9±11.1), 나트륨 농도가 정상인군의 행동장애 점수는 비정상군보다 유의하게 낮게 나타났다 (2.2±1.7 vs. 3.4±2.2). 또한 구리 농도가 정상인군의 MMDQ 총점은 비정상인 군보다 유의하게 낮았다 (15.7±11.9 vs. 24.9±16.9). 고찰: 조직 내 마그네슘과 구리의 농도에 따라 MMDQ 총점에서 차이를 보였으며, 조직 내 나트륨 농도는 행동장애 점수에 영향을 주는 것으로 나타났다. 그러나 이러한 미네랄 불균형이 생리전증후군의 증상을 악화시키는 원인으로 작용하는지에 대해서는 좀 더 자세한 연구가 필요할 것으로 사료된다. Objective: Premenstrual syndrome (PMS) is a disease with specific psychologic and physical symptoms on luteal phase. Its incidence is variable in 20~80%, but its cause is not definitely proved. Because progesterone and estrogen affect the balance of the body mineral, the alteration of progestorone and estrogen in the patients with PMS may effect the imbalance of tissue mineral, that can induce the specific symptoms of PMS. This study examines the relationship between symptoms of PMS and mineral count by tissue mineral test. Methods: Women who volunteered for the tissue mineral test completed MMDQ questionnaire and checked blood test for Ca, Mg, Na, K, Cu, Zn. The tissue mineral test used the hair not treated within 3 weeks and not washed within 3 hours. The hair was send to TEI for the analysis. We used SPSS (14.0) for statistical analysis. Results: The MMDQ score of the normal Mg group is significantly higher than the high Mg group (22.5±17.8 vs. 13.9±11.1), and the behavioral disorder score of the normal Na group is significantly lower than the low Na group (2.2±1.7 vs. 3.4±2.2). The MMDQ score of the normal Cu group is significantly lower than abnormal group (15.7±11.9 vs. 24.9±16.9). Conclusions: Total score of MMDQ showed difference according to magnesium and copper concentrations in tissue, and scores of behavioral disorder was affected by sodium concentration of tissue. Additional study about cause and effect relationship is required.
Decreased birth weight after prenatal exposure to wildfires on the eastern coast of Korea in 2000
En-Joo Jung,Ah-Young Lim,Jong-Hun Kim 한국역학회 2022 Epidemiology and Health Vol.45 No.-
OBJECTIVES: In April 2000, a series of wildfires occurred simultaneously in five adjacent small cities located on the eastern coast of Korea. These wildfires burned approximately 23,794 hectares of forestland over several days. We investigated the effects of prenatal exposure to the by-products generated by wildfire disasters on birth weight. METHODS: Birth weight data were obtained for 1999-2001 from the birth registration database of the Korean National Statistical Office and matched with the zip code and exposed/unexposed pregnancy week for days of the wildfires. Generalized linear models were then used to assess the associations between birth weight and exposure to wildfires after adjusting for fetal sex, gestational age, parity, maternal age, maternal education, paternal education, and average exposed atmospheric temperature. RESULTS: Compared with unexposed pregnancies before and after the wildfires, mean birth weight decreased by 41.4 g (95% confidence interval [CI], -72.4 to -10.4) after wildfire exposure during the first trimester, 23.2 g (95% CI, -59.3 to 13.0) for exposure during the second trimester, and 27.0 g (95% CI, -63.8 to 9.8) during the third trimester. In the adjusted model for infants exposed in utero during any trimester, the mean birth weight decreased by 32.5 g (95% CI, -53.2 to -11.7). CONCLUSIONS: We observed a 1% reduction in birth weight after wildfire exposure. Thus, exposure to by-products generated during a wildfire disaster during pregnancy may slow fetal growth and cause developmental delays.
윤정은(Yoon, Jung-En),임영환(Lim, Yeong-Hwan) 대한건축학회 2011 대한건축학회논문집 Vol.27 No.11
In recent years, the concept of eco-friendly architecture is changing to sustainable architecture, which encompasses the social, economic and cultural approaches. However, to implement sustainable building, there is lack of references presented realistic practices for architects and other relative practitioners. In order to solve these problems, there are various green building guidelines and these guidelines has been led to sustainable architecture. Certifications and guidelines for sustainable buildings have been independently used as the most common instructions among the planning criteria. However, in general, the certifications and guidelines for sustainable buildings are used together and create synergy effects. The relation between certification system and guidelines can be differentiated depends on the function of the guidelines. The types of guidelines are legislation, promotion, and supplementation. And the supplemental type of guidelines has complementary characteristic with green building certification system. For the appropriate regional development of sustainable architecture, supplemental type of guidelines is needed to be developed in the future. The supplemental type of guidelines is based on green building certification system and it reflects regional priority and requirements. And the guidelines follows the composition of green building certification systems and applies the items of environmental sustainability of regions from the certification systems. Also, the guidelines includes the economical sustainability and social sustainability which are not applied in the certification system. In this context, the aim of this study is to provide the basis for development of national green building guidelines by examining the correlation between green building certifications and guidelines.
Kwang-Pil Ko,En-Joo Jung,Younjhin Ahn,Seon-Joo Park,Young-Khi Lim 건강기능식품미래포럼 2022 건강기능식품미래포럼 학술지 Vol.2 No.4
Diabetes, if left untreated, can cause many health complications. Type 2 diabetes is known to be primarily due to lifestyle and thus, efforts have been made to reduce its risk by diet particularly of vegetables containing various antioxidants. In the present study, this possibility was investigated by examining association between the plasma level of enterolactone, a metabolite of food lignans and the risk of type 2 diabetes and the association was compared between producers and non-producers of equol, a metabolite of soy isoflavone. The study population was composed of 693 cases and 698 matched controls within the Korean Genome Epidemiology Study. Logistic regression models were used to compute the odds ratio (OR) and 95% confidence intervals (CI). Stratified analysis was done to examine the association between plasma enterolactone concentration and risk of type 2 diabetes, and then, this association was examined in terms of sex and status of equol producing ability. In female, compared with the reference level, a marginally significant risk reduction was found at the highest concentration of enterolactone (for the highest category: OR, 0.68; 95% CI, 0.46–1.01). In equol producers among women, the highest concentration of enterolactone significantly decreased the risk of type 2 diabetes (OR, 0.58; 95% CI, 0.34–0.96). In equol non-producers among women, however, the concentration of enterolactone was not associated with the risk of type 2 diabetes. In male, enterolactone concentration was not associated with risk of type 2 diabetes regardless of equol producing status. In conclusion, high plasma concentrations of enterolactone were associated with a decreased risk of type 2 diabetes particularly, in equol producing female.
임희순 ( Hee Sun Lim ),문영주 ( Yong Ju Moon ),정재은 ( Jae En Jung ),김민정 ( Min Jung Kim ),황성진 ( Sung Jin Hwang ),김진홍 ( Jin Hong Kim ),김장흡 ( Jang Heub Kim ),조현희 ( Hyun Hee Jo ) 대한산부인과학회 2007 Obstetrics & Gynecology Science Vol.50 No.5
Adenofibromas of the uterine cervix, which are classified as benign tumors of mixed epithelium and mesenchymal cells, are extremely rare. Most common symptom is usually abnormal genital bleeding. It is very difficult to diagnose preoperatively. Recommended method of treatment is total hysterectomy, because it usually recurs. We experienced a case of adenofibroma of the uterine cervix with increased CA125, so report it with a review of the literature.