Chunghyul-Dan(Qingxie-Dan) Improves Arterial Stiffness in Patients with Increased baPWV

Park, Seong Uk,June, Woo Sang,Moon, Sang Kwan,Ko, Chang Nam,Cho, Ki Ho,Kim, Young Suk,Bae, Hyung Sup 경희대학교 동서의학연구소 2006 東西醫學硏究所 論文集 Vol.2006 No.-

Arterial stiffness is an important, independent determinant of cardiovascular risk. Pulse wave velocity (PWV) has been used as a valuable index of arterial stiffness and as a surrogate marker for atherosclerosis. Chunghyul-dan (CHD) has anti-hyperlipidemic activity, anti-inflammatory activity and anti-atherogenic effects. To determine its clinical effect on increased arterial stiffness, we examined whether CHD improves arterial stiffness in patients with increased brachial-ankle PWV (baPWV). Thirty-five subjects with increased baPWV (> 1400 cm/sec) were recruited and randomized to a treatment group (20 subjects) or a control group (15 subjects). The treatment group was administered CHD at a dose of 600 mg three times a day for 8 weeks, and the control group received no medication (observation only). baPWV was assessed using a pulse pressure analyzer at baseline and after 8 weeks. Blood pressure and serum lipid profile were monitored in the treatment group. Our results indicate that baPWV was lowered significantly in the treatment group after 8 weeks of medication (p < 0.05), but not in the control group. Moreover, there were no significant changes in blood pressure and serum lipids profile except triglyceride level suggesting that the effect is largely independent of CHD's lipid-lowering effect or a blood pressure change. In conclusion, CHD appears to improve arterial stiffness in patients with increased PWV.

컴퓨터를 활용한 교수-학습 방안에 관한 연구(I)

문창현,조용욱 신라대학교 자연과학연구소 2002 自然科學論文集 Vol.10 No.-

A modem society has been changed continuously, and this change intends to become to be the information society with increasing information. The education of this kind of society have to teach the necessary knowledges, valuation, techniques and attitudes which support the request of present society. For this social requirement, new systematic teaching-learning methods and materials are achieved by computer media which can provide us the knowledge efficiently and make teachers to escape traditional instruction. But the introduction of computer for the school education can not guarantee students self-controlled studying. Therefore, we need to the computer software in the place where the educational effect is expected. And computer have to use in school-education, and it is not offered as the form to provide the fried information but as the form to provide the things that students can research something freely. The present thesis shows a new teaching-learning material for students' better understanding about math-education by using computer which is a part of the curriculum. That is, the purpose of this paper is to introduce one method for school-education in classroom for the forthcoming future.

문제해결을 위한 발견술

문창현,조용욱 신라대학교 자연과학연구소 2003 自然科學論文集 Vol.12 No.-

A modern society has been changed continuously, and this change intends to become to be the information society with increasing information. The education of this kind of society have to teach the necessary knowledges, valuation, techniques and attitudes which support the request of present society. The goal of mathematics education is to give students mathematical thinking power and to help them solve the problems with a logical and creative thinking in the problems of reality in daily life. Since 1980s, as far as mathematics education is concerned, the improvement of ability to solve the problems has been emphasized. For this purpose, we will investigate G. Polya's mathematical heuristics. Also we will investigate 'reversely solving', among of the many strateges, which can increases metacognition by conversely thinking.

문제해결을 위한 메타인지

문창현,조용욱 신라대학교 자연과학연구소 2003 自然科學論文集 Vol.12 No.-

The goal of mathematics education is to give students mathematical thinking power and to help them solve the problems with a logical and creative thinking in the problems of reality in daily life. Since 1980s, as far as mathematics education is concerned, the improvement of ability to solve the problems has been emphasized. For this purpose, we will investigate the concept of metacognition of Flavell and Schoenfeld's. Also we will investigate 'reversely solving', among of the many strateges, which can increases metacognition by conversely thinking.

제주도 양식넙치, Paralichthys olivaceus의 스쿠티카충병 발생 동향

진창남,이창훈,오상필,정용욱,송춘복,이제희,허문수 한국어병학회 2003 한국어병학회지 Vol.16 No.2

The research was carried out to know the occurrence trend of scuticociliatosis and mortality of fingerlings in flounder. The diseased fish were collected from on-land rearing farms and hatcheries of flounder in Jeju Island form January 1991 to December 2001. Occurrence of scuticociliatosis was about 10% of total occurred diseases for 1991 to 1996, but increased to 34.5% in 2001. Although monthly occurrence of seuticociliatosis was not related to season from 1999 to 2001, the highest occurrence was revealed in July and August. Mixed infections of bacteria including Vibrio sp., Edwardsiella tarda, Streptococcus sp., and Flexibacter sp., with seuticociliates were observed. Among the bacteria, Vibrio sp., was the highest frequency(40.1%), and the lowest one(10.1%) was Streptococcus sp., Mortality of fingerlings by seuticociliates was different sharply according to size of fish. Mortality of infected fingerlings below 7㎝ of total length was 53.8%, while that of normal fingerling above 7㎝ of total length was 13.2%. When fish were grown above 25㎝, mass mortality by seuticociliates infection was decreased markedly.

腦硬塞患者의 血壓·脈搏 및 腦血流에 대하여 水溝-承漿穴 電鍼刺戟이 미치는 影響

박성욱,문상관,고창남,조기호,김영석,배형섭,이경섭 경희대학교 1997 慶熙醫學 Vol.13 No.4

우리나라 지역 직업성질환 감시체계의 현황과 전망

임종한,장성실,김성아,문재동,채창호,홍윤철,김수영,김진석,김영욱,한상환,이혜숙,원종욱,송동빈,하은희,강성규 대한산업의학회 2001 대한직업환경의학회지 Vol.13 No.2

기존의 특수건강진단과 작업환경측정을 통한 직업병 관리가 진폐증, 소음성난청 등의 소수 특정질환에 국한되고 실제 직업병 발생 규모 파악이나 신종 직업병의 발견에 한계를 보인다는 사실은 산업의학전문가들 사이에서도 공감을 이루고 있다. 미국과 영국 등에서의 직업성질환 감시체계에 대한 경험은 우리 나라의 직업성질환 감시체계 구축에도 새로운 자극제가 되면서, 1998년이후 인천, 대전, 여천, 구미, 부울경 지역에서 지역 직업성질환감시체계를 산업보건관리의 중요한 시스템으로 구축하려는 노력이 확산되고 있다. 새로이 구축되어지는 이들 지역 직업성질환 감시체계는 감시하고자 하는 대상질환, 활용 가능한 인적자원 및 자료원, 지역 의료체계의 특수성 등에 따라서 목적과 방법을 달리하면서 독특한 형태로 발전을 하고 있다. 각 지역단위 감시체계들이 그 상황에 맞게 독특한 목적과 전략들을 발전 시키면서도, 향후 발전할 국가적인 차원의 직업성질환 감시체계 구축을 위하여 직업성질환 감시의 기본 전략 등을 공유하는 등의 노력이 필요하다. 환례 정의 및 기본적인 등록 서식의 공유, 직업성질환 감시 자료원의 발굴, 공동의 정보 네트워크 및 직업성질환 감시 데이터베이스 구축 등 직업성질환 감시활동을 지원하기 위한 여러 기초 인프라 구축에 힘을 모아야 할 것이다. 우리 나라에서 직업성질환 감시체계를 성공적으로 구축하기 위해서는 수집된 자료의 질 관리를 위한 직업성질환 감시의 원칙 제정과 감시 전략의 공유 등이 필요하며, 전국적인 직업성질환 감시체계의 하부구조라고 할 수 있는 지역감시체계의 기초 토대 마련과 강화작업이 절실하게 필요하다.

烏貝散이 흰쥐 胃의 Gastrin, Histamine, Somatostatin 면역반응세포에 미치는 영향

이시섭,나현욱,고병문,이광규,이창현 대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.5

To investigate the elects on the administration of Opae-san in rats. Opae-san (500mg/day) and omeprazole(10mg/day) were administration with stomach tube for 4 weeks and 8 weeks. This experiment were investigated numerical change of immunoreactive cells of gastric, histamine and somatostatin in rat stomach mucosa by the immunohistochemical method. The results were as follows : 1. In Opae-san administration group for 4 weeks, the number of gastric immunoreactive cells were increased in one and a half times than that of control group. In omeprazole administration group for 4 weeks, the number of gastric immunoreactive cells were increased in four times than that of control group. In Opae-san administration group for 8 weeks, the number of gastric immunoreactive cells were increased four times than that of control group. In omeprazole administration group for 8 weeks, the number of gastrin immunoreactive cells were increased in six times than that of control group. 2. In Opae-san administration group for 4 weeks, the number of histamine immunoreactive cells were increased in two times than that of control group. In omeprazole administration group for 4 weeks, the number of histamine immunoreactive cells were increased in six times than that of control group. In Opae-san administration group for 8 weeks, the number of histamine immunoreactive cells were increased three times than that of control group. In omeprazole administration group for 8 week, the number of histamine immunoreactive cells were increased in seven times than that of control group. These results suggest that Opae-san extracts inhibit the secretion of gastric acid and this extract use to therapeutic herb of gastric disorders related to the hyperacidity and gastric ulcer.

Operating characteristics of 3RT heat pumps

Chang-Uk Moon,Kwang-Hwan Choi,Jung-In Yoon,Min-Ju Jeon,Seong-Kwan Heo,Yo-Han Sung,Sung-Hyeon Park,Jin-Kook Lee,Chang-Hyo Son 한국마린엔지니어링학회 2017 한국마린엔지니어링학회지 Vol.41 No.2

Investigations of the microstructure evolution and tensile deformation behavior of austenitic Fe-Mn-Al-C lightweight steels and the effect of Mo addition

Moon, Joonoh,Park, Seong-Jun,Jang, Jae Hoon,Lee, Tae-Ho,Lee, Chang-Hoon,Hong, Hyun-Uk,Han, Heung Nam,Lee, Jaeeun,Lee, Bong Ho,Lee, Changhee Elsevier 2018 Acta materialia Vol.147 No.-

<P><B>Abstract</B></P> <P>A series of Fe-30 wt%Mn-10.5 wt%Al-1.1 wt%C steels with Mo addition from 0 to 5 wt% were prepared to investigate the effect of Mo on the microstructure and tensile deformation behavior of austenitic lightweight steel. When the Mo content was below 4 wt%, the microstructure of solution-treated samples consisted of austenite and κ–carbide, while Mo-enriched M<SUB>6</SUB>C and M<SUB>23</SUB>C<SUB>6</SUB> carbides were additionally precipitated in samples containing Mo more than 4 wt% during a solution treatment at 1050 °C. These carbides inhibited austenite grain growth during the solution treatment, resulting in significant grain refinement in the samples containing more that 4 wt% of Mo. Tensile test results showed that the yield strength gradually decreased with an increase in the Mo content up to 3 wt% due to the suppression of κ–carbide precipitation, whereas it significantly increased when the Mo content exceeded 4 wt% due to grain refinement and precipitation strengthening caused by Mo-enriched carbides. During the tensile deformation, the strain hardening rates of all alloys increased and then the deformation mode subsequently changed with an increase in the Mo content from shearband-induced plasticity (SIP) to microband-induced plasticity (MBIP). Finally, the change in the κ-carbide precipitation behavior upon the addition of Mo and its effect on the deformation behavior were carefully analyzed and discussed through nanoindentation experiments, first-principles calculations and atom probe tomography analyses.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>