Fluoride, Bisphosphonate 및 Gallium이 상아질 흡수 억제에 미치는 영향

백은영,유윤정,노병덕,최윤정,이승종 大韓齒科保存學會 1997 Restorative Dentistry & Endodontics Vol.22 No.2

Replacement resorption is followed by the delayed replantation of an avulsed tooth. Currently no effective treatment is substantiated for replacement resorption. The purpose of this study was to investigate the effect of stannous fluoride, bisphosphonate(etidronate disodium) and gallium nitrate, which have been shown to reduce dentin resorption, on human dentin. Osteoclasts were collected from tibeas of chich embryo. The cells were well agitated to prevent adhesion and seeded onto the sliced human dentin wafers which had been soaked in either culture media(control), or several different concentrations of stannous fluoride, etidronate disodium(1-hydroxyethylidene-1, 1-bisphosphonate disodium), and gallium nitrate. Resorption was measured by counting the number of resorptive pit produced by the cells. Results are ad follows. Stannous fluoride and etidronate disodium showed statistically significant reduction of dentin resorption(p<0.05) but the effect of stannous fluoride seemed to be its high cytotoxicity. Etidronate disodium did not show cytotoxicities in all experimented concentrations. Gallium nitrate did not show differences in resorption either between different concentrations of from the control group.

Foley catheter를 이용한 관골궁 골절 정복술

양병은 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.4

The zygomatic bone occupies a prominent and important position in the facial skeleton. The zygoma forms a significant portion of the floor, lateral wall of the orbit and the zygomatic arch, otherwise known as the malar eminence, which plays a key role in the determination of facial morphology. It is structure where the masseter muscle is inserted on the ventral part of the arch, and participates in the formation of the face, giving it a prominence of each cheek and a round outline. It is prone to fracture due to its bony prominence. Between the zygomatic arch and the skull, the coronoid process of the mandible moves freely when the mouth is opened and closed. A fracture which depresses this arch generally implicates a partial or total obstruction of the movement of the condyle and of the coronoid process of the mandible, changing the opening and closed. A fracture which depresses this arch generally implicates a partial or total obstruction of the movement of the condyle and of the coronoid process of the mandible, changing the opening and closure of the mouth. these fractures may also be responsible for the so called false ankylosis of the TMJ. The author describes a simple technique for reducing zygomatic arch which is displaced medially and impinges on the coronoid process. The technique is concerning the alevation of depressed fracture of zygomatic arch using the foley catheter. I think that this technique would be avilable for out patient department under local anesthesia and intravenous conscious sedation. Also, it would be used in postoperative stabilization of reduced comminuted zygomatic arch fracture and used in reduction malarplasty.

이성질체 분리를 위한 선택적 분리막 제조에 관한 연구

장은정,김병식,김민 한국공업화학회 2003 응용화학 Vol.7 No.2

Racemate is same chemical property and physical property, hard to separate by general method. In this study, separated racemate to use MIP(Molecularly Imprinted Polymeric) Membranes by simple process and high selectivity. The functional monomers were co-polymerised in the presence of a target/imprint molecules, which acts as a molecular template. Subsequent removal of the template molecules left behind functionalised cavities that are able to recognize the template molecules. Composite two types membrane imprinted with L-tryptophane(L-Trp) were developed using uv-irradiated polymerization. As a result, membranes covered with a thin film of imprinted polymer selective to L-Trp were obtained with different degrees of modification.

녹차 및 결명자 추출물의 치주조직병 원인균에 대한 억제효과

이은숙,안태영,윤정중,국중기,이병래,김동기 대한구강보건학회 2003 大韓口腔保健學會誌 Vol.27 No.4

It is known that the periodontal disease is caused by infection of inner oral bacteria as a suffering disease to human mankind for a long time. It can make the various clinical symptoms such as gingiva, bleeding, formation of periodontal pocket, loss of attached gingiva, collapse of alveolar bone and halitosis, and is known to the major contributor of loss of teeth. This study investigated the growth restraint effect of Camellia sinensis and Casia tora. As a result of study, the minimum restraint concentration of standard microbe on F. nucleatum for extracts from C. sinensis showed 2.5, 0.63 and 1.25 mg/ml, respectively and minimum restraint concentration of clinical separation microbe on F. nucleatum for extracts from C. sinensis showed 2.5 and 5.0 mg/ml. The minimum restraint concentration of standard microbe and clinical separation microbe, respectively. Meanwhile, the minimum restraint concentration of standard microbe and clinical separation microbe on F. nucleatum for extracts from C. tora showed 2.5 and 2.5-5.0 mg/ml, respectively. The minimum restraint concentration of standard microbe and clinical separation microbe for P. intermedia, P. nigrescens, P. gingivalis, and P. endodontalis showed above 5.0 mg/ml for standard microbe and above 5.0 mg/ml for clinical separation microbe, respectively. As a result of investigating the cell toxicity for each extracts, extracts from C. sinensis does not showed the toxicity for the cell below the concentration of 2.5 mg/ml, but it showed toxicity for the cell above concentration of 2.5 mg/ml and it decreased the existence ratio for the cell. Meanwhile, in the case of C. tora, it increased the multiplication ratio below the concentration of 1.25 mg/ml compared to the subject group and it decreased gradually the multiplication ratio that the growth ratio for the cell is increased better than subject group. As a result of this study, extracts from C. sinensis was more effect on the growth restraint effect against periodontopathogens than extracts from C. tora and is proven that it is possible for use as a oral mouthrinsing liquids in the near future. On the basis of results of this study, it is judged that the study for reaction mechanism and discrete clinical test for implementation should be needed.

귀출파징탕藥鍼의 抗血栓, 抗炎症, 鎭通 및 抗酸化效果

宋炳基,李京燮,宋銀姬 慶熙大學校韓醫科大學韓醫學硏究所 1999 慶熙韓醫大論文集 Vol.22 No.1

This study was projected to investigate the effects of Kwuichulpajing-tang aqua-acupuncture solution manufactured by water-alcohol method. In vivo, to observe the anticoagulative, antiinflammatory and analgesic effects of Kwuichulpajing-tang aqua-acupuncture at Kwanwon(CV4), the experimental animals were divided into a normal, control and two experimental groups. Each of them had 6 animals. As the normal group was untreated, the control group was injected with normal saline(0.1㎖/100g) at Kwanwon(CV4) s.c., and then injected with induction medicine. One of the experimental groups (Sample I group) was injected with 25.0 ㎎/㎖ Kwuichulpajing-tang aqua-acupuncture solution(0.1㎖/100g) at Kwanwon (CV4) s.c., and then injected with induction medicine. The other experimental group(SampleⅡgroup) was injected with 50.0 ㎎/㎖ Kwuichulpajing-tang aqua-acupuncture solution (0.1㎖/100g) at Kwanwon(CV4) s.c., and then injected with induction medicine. The results of the experimental groups were compared with that of the control group. In vitro, the effects of Kwuichulpajing-tang aqua-acupuncture solution on hyaluronidase activity, hydrolysis of casein by trypsin, heat-induced hemolysis and the antioxidative effect were observed. The results were as follows : 1. The effects of Kwuichulpajing-tang aqua-acupuncture at Kwanwon on the intravascular coagulation in rats induced by endotoxin(0.5㎎/㎏) i.v. were that the blood platelet and white blood cell counts were significantly increased in both experimental groups. the blood fibrinogen content was significantly increased in SampleⅡgroup and the prothrombin, the activated partial thromboplastin and thrombin times were significantly shortened in both experimental groups. 2. The carrageenin-induced mice paw edema was significantly decreased in both experimental groups. 3. The histamine-induced mice paw edema was significantly decreased in both experimental groups. 4. The histamine-induced vascular permeability was significantly decreased in SampleⅡgroup. 5. The writhing syndrome induced by acetic acid was significantly decreased in SampleⅡgroup. 6. The response time of mice on 70℃ heat plate was significantly prolonged in SampleⅡgroup. 7. The hypnotic duration induced by pentobarbital-Na was significantly increased in both experimental groups. 8. Kwuichulpajing-tang aqua-acupuncture solution had antioxidative effect and inhibited hyaluronidase activity, trypsin activity on hydrolysis of casein and heat-induced hemolysis in vitro.

선비문화가 조선시대 별서정원에 미친 영향에 관한 연구 : 보길도원림, 소쇄원, 남간정사, 다산초당을 중심으로

양병이,박은영,박휘 한국전통조경학회 2003 한국전통조경학회지 Vol.21 No.1

There was no difference between the designer and the user of gardens in Choson Dynasty. And the gardens were cultivated by the scholars in the time, called 'Sunbi(士)'. The studies of gardens of Choson Dynasty have, these days, been concentrated on just physical parts and existing data on them. So, there is a lack of understanding the background of garden constructions and their designers. This study focuses on the designers of the gardens. In addition, since most of designers were the scholars, we are also concerned with their culture. The areas for case study are Yun Seun-do's Buyongdong garden, Yang San-bo's Soseawon, Song Si-yeul's Namganjungsa, and Jung Yag-yong's Dasanchodang. These four gardens are representatives of the villa gardens of Chosen Dynasty that reflect Sunbi culture. We studied how Sunbis' lives were reflected on every corners of the gardens. The result of the study is to show how harmoniously spaces and physical parts in each gardens match with four categories of spritual values(a view of nature, a moral sense, scholastic pursuit, and a life of leisure) that constitute the cores of Sunbi culture.

지체장애 아동의 놀이 환경 기본 계획에 관한 연구

김영은,강병근,성기창,이건하 한국의료복지시설학회 2003 의료·복지 건축 Vol.9 No.2

The elements of a medium for gathering the able bodied and the disable bodied children are examined within the scope of this study. Starting from the importance of play for the children, the characteristics and the properties of middle childhood are closen as domain. This study showed that though most of the playground sites were accessible to Physically disabled Children, and were safety. For Physically disabled Children. the opportunities to play in a play area depend largely on the accessibility of the facilities. this study also explored the play experience of children with disability. The play spaces and the playgrounds including the equipment are examined. The results of study suggest there be creatived planning items in terms of accessibility and domain, which in detail. are summarized in following six points: Accessibility. Barrier-free. convenience, movement, safety. domain. A guideline on the design of an accessible & safety playground for Physically disabled Children should be made.

姙娠 및 分娩에 미치는 達生散의 效果에 關한 硏究

李恩美,李京燮,宋炳基 慶熙大學校 1986 論文集 Vol.15 No.-

In order to study the effects of Dalsaengsan, reputed to be the effective for the remedy and treatment of hard labor, experiments regarding the antiabortive effect of Dalsaengsan on the pregnant rats and the effect of it on the uterine smooth muscle strips of nonpregnant rats were carried out. The results were as follows 1. The drug administered on the uterine muscle strips of nonpregnant rats caused the effect of uterine relaxation in proportion to concentration of the drug. 2. The drug administered on the uterine contraction induced by oxytocin or prostaglandin F_(2α) of nonpregnant rats caused the effect of uterine relaxation in proportion to concentration of the drug. 3. The drug administered on the antiabortive effect when the dosage of the drug was 640 ㎎/㎏. 4. The effect of extracted powder and mixture of each extracted powder was nearly the same on the relaxation effect of the drug on the uterine muscle strips of the nonpregnant rats, but the effect of the former was better than that of the latter on the antiabortive effect.

병원정보시스템의 경영전략적 활용방안에 관한 연구

이은효,신종연,윤병준,김영훈 서울보건대학 1999 서울보건대학 부설 병원경영연구소 논문집 Vol.4 No.2

This study includes an empirical analysis of utilization of strategic management with hospital information system and a policy implication on hospital management. The purposes of this study are to analyze the effects of strategic information and implementation on the major performance factors. For this study. the materials used are mailing survey data of 65 hospitals and related literature was reviewed. Crosstabulation and multiple response analysis were made to find the frequencies by groups. ANOVA and multiple regression analysis were adopted to examine the differences and the relationship between variables involved. The major findings are as follow: 1. Internal information needed for strategic management focuses on the patients' data and the ones of services being delivered. Using portion of financial indices also ranked 2nd by respondents. but financial analysis was not performed frequently. 2. The Effects of strategic information on the hospital management environment were the most in hospital planning and hospital administration and medical support tasks. Ane the effects of assessment of the external factors and rapidity and accuracy of decision making, however. were relatively low. 3. The more computer system group satisfy planning group on the material requested by planning group. the more effects of cost reduction and service promotion have favorable results. Besides. the more computer education and PR are performed. the more efficiencies of hospital management have favorable results. In result of more exploration, the relationship of between computer education and PR item and satisfaction level of planning group on requested material and cost reduction effects was statistically significant. Of the above results. there are favorable effects on the major performance factors. However. there are few results of being performed on systematic strategic planning, action and management. With regard to hospital management information system, there are many challenges in the future when applying strategic management methods. Hospital executives must begin to use information system strategically for survival and growth in the 2000s.

공기 제습용 무기막의 제조 및 특성

김정은,김병문,송근호,장화익,이광래 강원대학교 산업기술연구소 2006 産業技術硏究 Vol.26 No.B

Recently, the humidity adjustment of indoor air is of great importance in air conditioning system as a applied, in buildings, vehicles, and containers for storage and transport of perishable products. Membrane dehumidification or air is potentially attractive because it offers low capital and operating costs, along with low energy consumption. And membrane dehumidification process attracted the attention of the public instead of the other dehumidification processes, such as adsorption, absorption, and refrigeration cycles and so on. In this study, the prepared hydrophilic inorganic membrane-based dehumidifiers (membrane air dehumidification) examined the performance of dehumidification. The surface-modified inorganic membrane prepared in this study showed high dehumidification efficiency (over 80%). Thc membrane might be very useful for dehumidification industries.