철모깍지벌레(Saissetia coffeae)에 대한 애홍점박이무당벌레(Chilocorus kuwanae)의 포식능력

진혜영,안태현,이봉우,전혜정,이준석,박종균,함은혜,Jin, Hye Young,Ahn, Tai Hyeon,Lee, Bong Woo,Jun, Hye Jeong,Lee, Jun Seok,Park, Jong Kyun,Ham, Eun Hye 한국응용곤충학회 2015 한국응용곤충학회지 Vol.54 No.4

This study, examined Chilocorus kuwanae for biological control of Saissetia coffeae. We measured basic developmental characteristics of C. kuwanae and its capability to prey on the second-instar larvae of S. coffeae by indoor breeding under the following conditions: $25^{\circ}C{\pm}2^{\circ}C$, humidity $70%{\pm}5%$, and day length 16L : 8D. The average daily consumption of the second-instar larvae of S. coffeae by C. kuwanae adults was approximately 77.5 larvae/day, which was significantly 2.8 and 2.9 times higher than consumption by Chrysoperla carnea and Cryptolaemus montrouzieri, respectively. During the nymphal period, C. kuwanae consumed a total of 659.0 second-instar larvae of S. coffeae. The interaction between C. kuwanae and the second-instar larvae of S. coffeae varied according to their densities, with the increase in C. kuwanae consumption rate noted to decelerate and gradually level off at the maximum, rsembling Holling's Type II functional response. Duration of egg to adult development varied from 21.1 days to nearly 27.9 days at temperatures of $25^{\circ}C{\pm}2^{\circ}C$. Hatchability, pupation rate, and adult emergence were greater than 72.3%, 77.8% and 83.3%, respectively. 철모깍지벌레의 생물적 방제를 위한 애홍점박이무당벌레의 포식능력과 기초 생태특성을 $25^{\circ}C{\pm}2^{\circ}C$, $70%{\pm}5%$, 16L : 8D로 설정된 사육실에서 검정한 결과, 애홍점박이무당벌레 성충은 하루에 77.5마리의 철모깍지벌레를 포식하여, 깍지무당벌레 포식력의 2.9배, 어리줄풀잠자리 포식력의 2.8배 이상의 뛰어난 포식능력이 관찰되었다. 1령 ~ 4령 유충 기간 동안 659.0마리의 철모깍지벌레를 포식하였고, 애홍점박이무당벌레와 철모깍지벌레의 밀도 별 상호작용을 조사한 결과 Holling (1959)의 기능반응곡선 제 II 형과 유사한 포식반응을 확인하였다. 애홍점박이무당벌레는 철모깍지벌레를 먹이로 공급했을 때 알에서 성충까지 21.1일 ~ 27.9일이 소요되었으며, 72.3%, 77.8%, 83.3%의 높은 부화율, 용화율과 우화율을 보였다.

소아 및 청소년기에서 골수이식 후에 발생할 수 있는 내분비 기능 부전

진혜영,최진호,임호준,서종진,문형남,유한욱 대한소아청소년과학회 2010 Clinical and Experimental Pediatrics (CEP) Vol.53 No.3

Purpose:Several complications can occur in patients who received bone marrow transplantation (BMT) during childhood and adolescence. This study aims to investigate endocrine dysfunctions after BMT so that better care can be provided to care for long-term survivors of BMT. Methods:One hundred patients (61 males, 39 females) were included in this study. Clinical parameters such as initial diagnosis, age at BMT, conditioning regimen, presence of graft-versus-host disease (GVHD), growth pattern, thyroid function, and pubertal status were retrospectively reviewed to evaluate risk factors associated with endocrine dysfunction. Results:Height standard deviation score (SDS) at BMT, after 1 year of BMT, and at the last visit were 0.08±1.04, -0.09± 1.02, and -0.27±1.18, respectively (P=0.001). Height SDS significantly decreased in patients who received total body irradiation (TBI) (P=0.017). One of the patients who received TBI demonstrated growth hormone deficiency. Thirty (31.9%) of 94 patients had compensated hypothyroidism. Incidence of compensated hypothyroidism was higher among those who had GVHD (odds ratio 2.82, P=0.025). Of the 32 patients (17 males, 15 females) who were over 14 years in male and 13 years in female at the last visit, 16 (3 males, 13 females) had increased luteinizing hormone (LH) or follicle-stimulating hormone (FSH). Abnormal elevation of LH or FSH was more common in females (odds ratio 30.3, P=0.001). Conclusion:The most common endocrine dysfunction was ovarian insufficiency. Regular check-up for endocrine function needs to be required due to high incidence of endocrine dysfunction in patients with BMT. 목적:소아와 청소년기에 골수이식을 받은 환자들은 여러 가지 조기 또는 후기 합병증이 발생할 수 있다. 본 연구에서는 이식 후 발생할 수 있는 내분비 기능 부전에 대해 분석하여 이식 후 추적 관리에 도움이 되고자 하였다. 방법:골수이식을 받은 100명(남자 61명, 여자 39명)의 환자들을 대상으로 진단명, 이식 당시 연령, 전처치 방법, 만성 이식편대 숙주병 유무, 성장 패턴, 갑상샘 기능, 사춘기 발달 상태 등을 후향적으로 조사하여 내분비 기능 부전과 관련이 있는 위험 인자가 있는지 분석하였다. 결과:이식 당시, 이식 1년후, 최종 내원시의 신장 표준편차 점수는 각각 0.08±1.04, -0.09±1.02, -0.27±1.18로 의미있게 감소하였다(P=0.001). 전처치로 TBI를 받은 경우 TBI를 받지 않은 군에 비하여 이식 전보다 신장 표준편차 점수가 더 많이 감소하였다(P=0.017). TBI를 시행한 환자 중 1명에서 성장 호르몬 결핍을 보였다. 갑상샘 기능 검사를 시행한 94명 중 30명(31.9%)이 보상성 갑상샘저하증이었고 만성 이식편대 숙주병이 있었던 환자에서 보상성 갑상샘저하증의 빈도가 높았다(odds ratio=2.82, P=0.025). 최종 내원 시 만 14세 이상 남자 17명, 만 13세 이상 여자 15명 중에서 비정상적인 LH 또는 FSH의 상승을 보인 경우는 남자 3명, 여자 13명으로 여아가 의미 있게 많았다(odds ratio=30.3, P=0.001). 결론:소아나 청소년기에 골수이식을 받은 환자에서 가장 흔한 내분비 기능 이상은 난소 기능 부전이며 그 외 높은 빈도의 내분비 기능 이상을 보이므로 정기적인 내분비 기능 검사가 필요하다.

문화기본법제정을 통해본 문화정책 변화 탐색

진혜영,고재욱 한국스포츠엔터테인먼트법학회 2016 스포츠와 법 Vol.19 No.2

The fundamental Act on Culture was passed by the National Assembly in December 10th 2013, and the new law became effective from March 31st 2014. This law which composed of thirteen articles, has great significant to enact cultural rights for the public as the Fundamental Act. Regarding the cultural rights as the rights for the people, the changes of the cultural policies were examined by each regime while establishing of the Fundamental Act on Culture. The cultural policy represents that the planning and execution on cultural administration has performed by the government organization, which places emphasis to raise the cultural standard for the public through the cultural development. In this point of view, it would be able to evaluate in accordance with another policy as the higher authority of the local government under the meta-evaluation standards. With the Fundamental Act on Culture, it starts to build up the foundation for the cultural nation in the institutional coherence. At home and abroad the cultural contents, a fast-growing industry should be intensively supported and the cultural opinion leader and the volunteer in accordance with the local cultures by genre should be positively promoted by the governments. The Korean culture shows remarkable progress and cultural policy spreads around the world such as K-Pop with elitism. In order to narrow the gap between the elitist and the common people, the supporting policies for those who are isolated with culture should be maintained through the sustainable planned programs. In this regard the government should consider to open the cultural center with daily-life oriented programs on a nation-wide scale for everyone's cultural rights 「문화기본법」은 12월 10일 국회에서 통과하여 2014년 3월 31일부터 시행되었다. 이 법은 총 13개 조로 구성되었으며, 국민의 문화권을 기본법으로 제정하였다는데 의의가 있다. 국민의 권리라고 하는 문화권에 대하여, 2014년 「문화기본법」이 제정되기까지의 문화정책 변화에 대하여, 정권별로 살펴봤다. 문화 정책은 공공기관에 의해 수행되는 문화에 관한 사업의 계획과 집행을 의미하며, 문화발전을 통한 국민의 문화수준 향상에 중점을 두고 지방자치 단체의 상위정책으로서 또 다른 정책으로 평가할 수 있는 메타 평가기준이 될 수 있다고 한다. 「문화기본법」은 문화국가 기반조성의 제도적 차원에서 출발한 법인만큼 문화산업으로 급성장하고 있는 국내외 문화콘텐츠를 집중 육성하고, 지역문화를 고려한 영역별, 장르별 문화콘텐츠를 운영할 수 있는 문화지도자와 문화자원봉사자들의 공동창작을 위한 정부의 적극적인 지원정책이 요청된다. 한국의 문화는 많은 제도적 발전을 이루었지만, 정책은 현재 K-Pop같이 세계적으로 뻗어가고 있는 시점에서도 엘리트적 문화정책을 이어가고 있는 실정이다. 엘리트주의인 부유층과 일반 서민층의 문화적 차이에서 비롯되는 정서적인 격차를 줄이기 위한 노력으로 제도적인 지원이 요청된다. 이러한 관점에서 정부는 모든 국민 개개인의 문화권 획득을 위하여 생활밀착형 문화센터를 전국적으로 확대함으로써 문화소외계층의 참여도를 높이고 지속가능한 기획프로그램을 제도화하고 실행해야 할 것이다.

양치식물원 조성에 관한 연구

진혜영,김성식 한국임학회 2006 한국임학회 학술발표논문집 Vol.2006 No.-

진로인식 향상을 위한 가정 연계 초등 진로교육 프로그램 개발

진혜영,정혜영 이화여자대학교 교과교육연구소 2006 교과교육학연구 Vol.10 No.2

본 연구에서는 초등학교 아동의 진로인식 향상을 위한 방안의 하나로 가정 연계 진로교육 프로그램을 개발하여 아동들에게 다양한 진로 관련 활동을 통하여 진로인식을 향상시키고자 하였다. 본 프로그램은 Posner & Rudnitsky(1980)의 교육과정 설계 절차에 따라 이루어졌으며, 진로교육 영역을 단원으로 설정하여, 서울시 S초등학교 4학년을 대상으로 실시되었다. 평가는 프로그램 사전과 사후에 진로인식 검사를 실시하였고, 검사 결과는 대응(종속)표본 t검정으로 분석하였다. 또한 아동의 흥미와 참여도의 변화를 살펴보기 위하여 교사의 관찰과 아동의 자기평가 방법이 사용되었다. 아동과 학부모에게 설문지를 배부하였다. 연구결과, 프로그램 실시 집단은 자기 이해 영역, 일과 직업의 세계 이해 영역, 합리적인 진로 의사 결정 영역에서 통계적으로 유의미한 차이(p<.05)를 보였고 교사의 관찰과 아동의 자기 평가, 소감문, 설문지를 분석한 결과에서도 아동의 진로인식 향상에 있어 긍정적인 변화를 가져왔고, 자신의 미래생활과 직업에 대하여 관심과 기대를 갖고 준비하려는 태도가 형성되었다. 많은 학부모들이 진로교육 학부모자료에 대하여 높은 참여와 긍정적인 반응을 보였고 실제 자녀지도에 활용할 의사를 나타내었다. This study aims to develop career education program to increase career awareness for elementary school students. This program was based on Posner and Rudnitsky(1980)'s model of a course design and organized course curriculum into the following sections: self-understanding, understanding of jobs and work, positive job attitude and self job value criteria, and sensible career decision-making. This program was carried out 4th grade of an elementary school for 17 class hours during 6 weeks. The results showed that career awareness showed a statistically meaningful difference before and after the test in terms of self-understanding, understanding of jobs and work, sensible career decision-making except positive job attitude and self job-value criteria. It also showed the analysis of observation by teachers, self-examination by children, survey supported that the program made a positive change in career awareness of children and made parents changed to have affirmative attitude toward the program.

급성림프구성백혈병에서 면역조직화학염색에 의한 p16 단백질 소실의 의의

진혜영,강경인,김선영,윤유숙,강준원,조덕연,권계철,박경덕 대한소아청소년과학회 2008 Clinical and Experimental Pediatrics (CEP) Vol.51 No.1

Purpose:p16 gene, mapped to the 9p21 chromosomal region, has emerged as a candidate tumor suppressor gene in human neoplasm. It is an inhibitor of cyclin-dependent kinase and inhibits Rb phosphorylation. In a variety of tumors including childhood acute lymphoblastic leukemia (ALL), deletion and/or mutation of the p16 gene has been found. Despite their high frequency, the prognostic importance of p16 alterations is still controversial in ALL and has been reported to be either unfavorable or similar to that of other patients. We studied the correlation between loss of p16 protein confirmed by immunohistochemical staining and clinical outcomes of patients diagnosed as ALL. Methods:We performed an immunohistochemical staining for p16 protein in 74 cases of bone marrow biopsy slide initially diagnosed as ALL between January 1998 and December 2006. We reviewed the clinical manifestations, laboratory findings, treatment outcomes retrospectively. Results:Of 74 slides, 12 were negative for p16 protein. Seven were males and 5 were females with a median age at diagnosis was 5.8 (1.3-18.8) years. Initial WBC were 17,225 (500-403,300)/µL. By immunologic surface marker analysis, 7 patients were early pre-B CALLA (+) and 5 patients were T-cell ALL. Two patients of intermediate risk group had relapsed and died. Three patients had family history of breast cancer. Four patients died and overall survival rates were 53.5±18.7%. Conclusion:Loss of p16 protein is supposed to be an independent risk factor of childhood ALL associated with poor outcomes. In clinical setting, the clinician must take into account p16 status, not only at the genomic but also at the protein level. Further clinical experience on thoroughly investigated cases will help a better understanding between p16 status and clinical outcomes. (Korean J Pediatr 2008;51:73-77) Purpose:p16 gene, mapped to the 9p21 chromosomal region, has emerged as a candidate tumor suppressor gene in human neoplasm. It is an inhibitor of cyclin-dependent kinase and inhibits Rb phosphorylation. In a variety of tumors including childhood acute lymphoblastic leukemia (ALL), deletion and/or mutation of the p16 gene has been found. Despite their high frequency, the prognostic importance of p16 alterations is still controversial in ALL and has been reported to be either unfavorable or similar to that of other patients. We studied the correlation between loss of p16 protein confirmed by immunohistochemical staining and clinical outcomes of patients diagnosed as ALL. Methods:We performed an immunohistochemical staining for p16 protein in 74 cases of bone marrow biopsy slide initially diagnosed as ALL between January 1998 and December 2006. We reviewed the clinical manifestations, laboratory findings, treatment outcomes retrospectively. Results:Of 74 slides, 12 were negative for p16 protein. Seven were males and 5 were females with a median age at diagnosis was 5.8 (1.3-18.8) years. Initial WBC were 17,225 (500-403,300)/µL. By immunologic surface marker analysis, 7 patients were early pre-B CALLA (+) and 5 patients were T-cell ALL. Two patients of intermediate risk group had relapsed and died. Three patients had family history of breast cancer. Four patients died and overall survival rates were 53.5±18.7%. Conclusion:Loss of p16 protein is supposed to be an independent risk factor of childhood ALL associated with poor outcomes. In clinical setting, the clinician must take into account p16 status, not only at the genomic but also at the protein level. Further clinical experience on thoroughly investigated cases will help a better understanding between p16 status and clinical outcomes. (Korean J Pediatr 2008;51:73-77)

초록 : Anti-JK3가 동정된 JK null 혈액형 환자의 1예

진혜영,최유정,최영아,한정훈,김창현,최재열 대한임상병리사협회 2003 임상수혈검사학회 발표자료집 Vol.8 No.1

열대온실 및 열대식물 관리매뉴얼

진혜영,안태현,송정화,김성식 국립수목원 2010 연구간행물 Vol.2010 No.0

Hepatic glycogenosis in a patient with poorly controlled type 1 diabetes mellitus

진혜영,강대영,최진호 대한소아청소년과학회 2009 Clinical and Experimental Pediatrics (CEP) Vol.52 No.11

Hepatomegaly and liver dysfunction might develop in patients with diabetes mellitus due to glycogen deposition or nonalcoholic steatohepatitis. We experienced a case of hepatic glycogenosis in a patient with type 1 diabetes mellitus who presented with recurrent hypoglycemia, suggesting impairment of glycogenolysis and gluconeogenesis. A 10-year-old girl with a 4-year history of type 1 diabetes mellitus was admitted because of recurrent hypoglycemia and abdominal pain in the right upper quadrant. She had Cushingoid features and hepatomegaly that extended 6 cm below the right costal margin. Laboratory data and radiologic examination revealed elevated liver enzyme levels due to fatty liver. Periodic acid-Schiff (PAS) staining revealed intense glycogen deposition in the cytoplasm of the hepatocytes and PAS reactivity was lost with diastase treatment. At 2 months after administration of glucagon injection and uncooked cornstarch between meals and at bedtime, the hypoglycemic episodes and liver dysfunction improved. It is important to distinguish hepatic glycogenosis from steatohepatitis, because it is possible to prevent excessive hepatic glycogen storage in hepatic glycogenosis cases by strictly controlling blood glucose level and by glucagon administration. To prevent severe hypoglycemic symptoms accompanied by hepatic glycogenosis, we suggest that uncooked cornstarch, which is effective in maintaining blood glucose level, can also be administered.

국립수목원에서 만나는 약용식물

진혜영,김성식,주진순,안태현,이가연,송정화 국립수목원 2009 연구간행물 Vol.2009 No.0