중등도 및 고도 근시에서 라섹을 이용한 굴절교정수술 후 8년간의 임상성적

정병주,오태훈,정성근,Byung Ju Jung,Tae Hoon Oh,Sung Kun Chung 대한안과학회 2012 대한안과학회지 Vol.53 No.10

Purpose: To evaluate the long-term prognosis and complications of laser epithelial keratomileusis (LASEK). Methods: A retrospective study including 92 eyes of 46 myopic patients treated with LASEK from November 1999 to February 2003 was performed. Follow-up visits were at 3 months, 6 months, 1 year, and 8 years. Treated eyes were divided into 2 groups according to preoperative spherical equivalent (SE) : low and medium myopia (<-6.0 D), and high myopia (>-6.0 D). The main outcome measures were UCVA, BCVA, postoperative SE, efficacy index, safety index, predictability, and postoperative complications. Results: Preoperative visual acuity was 1.24 ± 0.42 log MAR, and the average of SE was -5.28 ± 1.63 D. Postoperative visual acuity log MAR was significantly improved compared to preoperative visual acuity, and the average of visual acuity was 0.12 ± 0.13 log MAR. The percentage of eyes within ± 1.0 D of emmetropia 8 years after having LASEK was 69.5% in the mild and moderate myopia group, and 63.6% in the high myopia group. There was no significant difference of safety index, efficacy index or complications between the 2 groups at 1 month, 3 months, 1 year, and 8 years. Safety index was maintained over 0.9 and efficacy index was larger than 0.8. There were no other complications during the observation period. Conclusions: An 8-year follow-up showed LASEK for mild to moderate and high myopia to be a safe and effective procedure. J Korean Ophthalmol Soc 2012;53(10):1438-1444

심한 기계성 위눈꺼풀 처짐을 유발한 눈물샘 눈꺼풀엽의 거대 다형성 샘종 1예

정병주,조양경,나태윤,Byung Ju Jung,Yang Kyeung Cho,Tae Yoon La 대한안과학회 2011 대한안과학회지 Vol.52 No.2

Purpose: To report a rare case of giant pleomorphic adenoma of the lacrimal gland involving the palpebral lobe causing severe mechanical ptosis and visual field defect, which was removed successfully. Case Summary: An 82-year-old man visited our clinic with a large protruding mass on his left upper lid that had grown for approximately 10 years causing severe ptosis. Preoperative orbital CT showed a 2.3 × 2.0 cm sized large mass which was suspicious of hemangioma. The mass was completely excised through a lid crease incision. The histopathologic examination showed typical findings of pleomorphic adenoma. After the surgery, preoperative mechanical ptosis was completely resolved and during the 6 months of follow-up, there was no abnormality of tear secretion and evidence of tumor recurrence. Conclusions: The authors experienced a rare case of giant pleomorphic adenoma of the lacrimal gland involving the palpebral lobe and resolved mechanical ptosis by complete removal of the tumor through a lid crease incision. J Korean Ophthalmol Soc 2011;52(2):241-245

중등도 및 고도 근시에서 라섹을 이용한 굴절교정수술 후 8년간의 임상성적

정병주 ( Byung Ju Jung ),오태훈 ( Tae Hoon Oh ),정성근 ( Sung Kun Chung ) 한국안전학회(구 한국산업안전학회) 2003 International Journal of Safety Vol.2 No.1

목적: 최근 국내에서 흔히 행하는 각막 굴절교정수술 방법의 하나인 라섹의 장기 예후에 대한 국내 보고가 없는바, 이를 평가하고자한다. 대상과 방법: 1999년 11월부터 2003년 2월까지 양안 라섹을 시행 받고, 3개월, 6개월, 1년, 8년까지 장기 경과관찰이 가능했던 근시환자46명, 92안을 대상으로 후향적 분석을 하였다. 평가 항목은 술 전 구면렌즈 대응치에 따라 경도 및 중등도근시군(제1군), 고도근시군(제2군)으로 나누고 나안시력, 최대 교정시력, 현성 구면렌즈대응치, 안정성, 효율성, 예측성, 수술 후 합병증 유무였다. 결과: 술 전 평균 나안시력의 로그 대응치는 1.24 ± 0.42, 술 전 평균 구면렌즈대응치는 -5.28 ± 1.63디옵터였다. 술 후 나안시력의 logMAR는 8년 후 평균 0.12 ± 0.13이었으며, 술 전보다 명백히 향상된 시력을 보였다. 구면렌즈대응치로 계산한 1디옵터 이내의 굴절이상은8년 후 경도 및 중등도 근시군에서는 69.5%, 고도 근시군에서는 63.6%였다. 술 후 1개월, 3개월, 1년, 8년째 안정성, 효율성, 부작용은두 군 간의 유의한 차이는 없었다. 안정성은 0.9 이상, 효율성은 0.8 이상으로 유지되었다. 술 후 수술과 관련된 유의한 합병증의 발생은 없었다. 결론: 술 후 8년간의 장기 경과관찰 결과, 경도 및 중등도 근시뿐만 아니라 고도근시에서도 효율적이고 안전한 수술방법이라 생각한다. Purpose: To evaluate the long-term prognosis and complications of laser epithelial keratomileusis (LASEK). Methods: A retrospective study including 92 eyes of 46 myopic patients treated with LASEK from November 1999 to February 2003 was performed. Follow-up visits were at 3 months, 6 months, 1 year, and 8 years. Treated eyes were divided into 2 groups according to preoperative spherical equivalent (SE): low and medium myopia (<-6.0 D), and high myopia (>-6.0 D). The main outcome measures were UCVA, BCVA, postoperative SE, efficacy index, safety index, predictability, and postoperative complications. Results: Preoperative visual acuity was 1.24 ± 0.42 log MAR, and the average of SE was -5.28 ± 1.63 D. Postoperative visual acuity log MAR was significantly improved compared to preoperative visual acuity, and the average of visual acuity was 0.12 ± 0.13 log MAR. The percentage of eyes within ± 1.0 D of emmetropia 8 years after having LASEK was 69.5% in the mild and moderate myopia group, and 63.6% in the high myopia group. There was no significant difference of safety index, efficacy index or complications between the 2 groups at 1 month, 3 months, 1 year, and 8 years. Safety index was maintained over 0.9 and efficacy index was larger than 0.8. There were no other complications during the observation period. Conclusions: An 8-year follow-up showed LASEK for mild to moderate and high myopia to be a safe and effective procedure. J Korean Ophthalmol Soc 2012;53(10):1438-1444

Quantifying effects of river stage control on groundwater system by cluster analysis and groundwater-level modeling

정병주(Byeongju Jung),김동훈(Dong-Hun Kim),문희선(Hee Sun Moon),김용철(Yongchul Kim) 대한지질학회 2021 지질학회지 Vol.57 No.1

2004년 3월 4-5일 한반도 대설 사례의 역학ㆍ열역학적 특성에 관한 수치 연구

정병주(Byoung-Joo Jung),홍성유(Song-You Hong),서명석(Myoung-Seok Suh),나득균(Deuk-Kyun Rha) 한국기상학회 2005 Asia-Pacific Journal of Atmospheric Sciences Vol.41 No.3

독일바퀴 알레르겐의 특성규명에 관한 연구

이기영,정병주,김규언,류정우(Jeong Woo Ryu),염혜영(Hae Yung Yun),박중원(Jung Won Park),홍천수(Chein Soo Hong),이한일(Han Il Lee),용태순(Tai Soon Yong) 대한소아알레르기호흡기학회(구 대한소아알레르기 및 호흡기학회) 1998 소아알레르기 및 호흡기학회지 Vol.8 No.2

목 적 : 바퀴벌레는 알레르기질환을 유발하는 중요한 기인항원이다. 우리 나라도 임상증상이 위중하여 이환율이 높은 바퀴항원에 의한 알레르기환자가 증가될 것으로 추정된다. 독일바퀴의 알레르겐은 최근까지도 논란이 되고 있다 이에 저자들은 독일바퀴의 주알레르겐을 규명하고자 본 연구를 실시하였다. 방 법 : 알fp르기피부시험 혹은 RAST검사에서 바퀴항원에 양성으로 나온 32명을 대상으로 하였다. 독일바퀴 조항원을 pretense inhibitor를 첨가한 경우와 첨가하지 않은 경우로 나누어 제조한 후 SDS-PAGE로 단백띠를 비교하였고 IgE immunoblot으로 독일바퀴 알레르겐을 규명하였다. 결 과 :조항원에 pretense inhibitor를 첨가하지 않았을 경우에는 41 kD 단백띠는 관찰할 수 없었고 32, 55 및 78 kD 단백띠가 관찰되었다. Allergogram상 15개 이상의 단백띠가 있었는데 그중 10 kD 단백띠는 해상도는 높지 않으나 대상환자들의 혈청과 31%에서 결합하여 가장 호발하였으며 21, 25, 36 및 52 kD 단백띠는 각각 22, 28, 16, 및 19%의 환자들에서 관찰되었다 결 론 : 바퀴벌레와 같은 동물성 알례르겐의 조항원을 제조할 때에는 체내에 존재하는 pretense들의 작용을 억제시키는 물질을 첨가하여 주는 것이 좋을 것으로 생각되고, IgE와 주로 결합하는 바퀴단백은 분자량이 10, 21, 25, 36 및 52 kD이 중요한 단백으로 추정된다. Purpose : Cockroaches have been reported one of the major causes of allergic disease such as bronchial asthma and allergic rhinitis. About 10% of children and 20% of adult respiratory allergy patients have positive results of allergy skin tests to cockroach allergen. This finding suggests that cockroach is also important allergen in Korea. Among 4,000 species, German cockroach seems predominant species in the Korean peninsula. Identification and characterization of the major allergen is the first step in German cockroach allergen research. But, there have been controversies. It may depends upon different identifying methods. The aim of our study was to identify the major allergen in German cockroach using Westernblot. Methods : Crude German cockroach allergen extracts with or without protease inhibitor cocktail mixture were prepared, and protein patterns of these two extracts were compared using SDS-PAGE and Coomassie stain. Sera from 32 atopic asthmatic patients with positive allergy skin test against cockroach allergen were used for IgE immunoblot. Results : Coomassie stain after SDS-PAGE demonstrated some discordance between the differently prepared crude allergen extracts. In comparison with the allergen extract which abolished endogenous protease activity, the untreated extract revealed new 32, 55 and 78 kD protein bands and 41 kD protein band was disappeared. About 60% of sera with positive allergy skin test revealed IgE binding bands in Westernblot. Among them, 10, 21, 25, 36 and 52 kD protein band might seemed important German cockroach allergen. Conclusion : Finding above may suggest that endogenous protease could denature allergenic proteins in the process of crude cockroach allergen extract. The 10, 21, 25, 36, and 52 kD might be the important allergens in German cockroach.

직난시 및 도난시에 따른 동축 소절개 백내장 수술의 난시와 고위수차의 비교분석

정현진,정병주,황형빈,김현승,Hyun Jin Jeong,Byung Ju Jung,Hyung Bin Hwang,Hyun Seung Kim 대한안과학회 2014 대한안과학회지 Vol.55 No.2

Purpose: To assess the changes of corneal astigmatism and higher order aberrations (HOAs) of the anterior and posterior corneal surface after cataract surgery with on-axis clear corneal incision in eyes with-the-rule (WTR) astigmatism and against-the-rule (ATR) astigmatism. Methods: This study included 50 patients who underwent phacoemulsification and IOL insertion through a 2.8-mm on-axis clear corneal incision. The eyes were divided into two groups: (1) 26 eyes with WTR astigmatism with a superior incision and (2) 24 eyes with ATR astigmatism with a temporal incision. During the follow-up period, visual acuity was measured, and the surgically induced astigmatism (SIA) and HOAs of the anterior and posterior corneal surface were measured with Pentacam? (Occlus, Wetzlar, Germany) preoperatively and 1 week, 1 month, and 2 months postoperatively. Results: There were no significant differences in UCVA and BCVA between the two groups. HOAs increased in both groups 1 week after surgery, but no significant differences were found between the groups (p > 0.05). Surgically induced astigmatism was larger in the WTR group than in the ATR group (p < 0.05). At postoperative 2 months, there were significant differences in HOAs between the two groups, and there were statistically significant differences in HOAs, oblique trefoil at front side, and in HOAs, horizontal coma at rear side (p < 0.05). Conclusions: In conclusion, superior incision in eyes with WTR astigmatism resulted in higher SIA compared to temporal incision in eyes with ATR astigmatism. Moreover, HOAs was significantly decreased in eyes with WTR astigmatism with superior incision. Thus, superior incision could be more effective in reducing corneal astigmatism in eyes with WTR astigmatism. J Korean Ophthalmol Soc 2014;55(2):182-189

재발성 폐렴 ( recurrent pneumonia ) 의 원인을 중심으로 한 임상적 고찰

신혜정(Hye Jung Shin),이현희(Hyun Hee Lee),박경화(Kyoung Hwa Park),정병주(Byung Ju Jeong),김규언(Kyu Earn Kim),이기영(Ki Young Lee) 대한소아알레르기호흡기학회(구 대한소아알레르기 및 호흡기학회) 1997 소아알레르기 및 호흡기학회지 Vol.7 No.2

목 적 : 재발성 폐렴은 비교적 흔한 문제임에도 불구하고 이에 대한 문헌이나 연구보고는 매우 적은 실정이다. 이에 저자들은 재발성 패럼의 빈도, 양상 그리고 동반편 질환 및 원인에 대하여 조사하고 재발성 폐렴의 평가 및 접근 방법을 제시하고자 하였다. 대 상 : 1986년 1월부터 1995년 12월까지 연계의대 세브란스병원 소아과에 폐렴으로 입원했던 환아 12,137명을 대상으로 하였다. 이들 중에서 재발성 페렴은 1년에 2회 이상 또는 상기 10년간 3회 이상 폐렴으로 진단받았던 환아로 각 발병간에는 최소한 1개월 이상의 간격이 있는 경우로 하였다. 방 법 : 재발성 폐렴 환아를 대상으로 빈도, 연령 분포, 재발 횟수에 대하여 알아보고 이들 재발성 폐렴 환아들 중에서 200명을 무작위로 선택하여 각 재발사이의 시간적 간격, 단순 흉부 X-선 사진상 병소의 위치, 평가 방법, 선행 요인 및 동반 질환에 대하여 알아보았다. 결 과 : 재발성 폐렴 환아는 840명으로 전체 패렴 환아의 6.9%였다. 연령별 분포는 1세 미만 95명(11.3%), 1-2세 355명(42.3%), 2-3새 162명(19.3%)이었으며, 재발 횟수는 1회가 66.9%로 가장 많았으나 최고 7회 재발한 경우도 있었다. 각 재발사이의 시간적 간격은 1-3개월이 45.2%로 가장 많았으며 최장 기간은 5년 2개월이었다. 병소의 위치는 원발성, 재발성인 경우 모두에서 양측 폐야를 침범하는 경우가 가장 많았다. 선행 요인 및 동반 질환은 매우 다양하였으나, 그중에서도 세기관지염(24.0%), 기관지 천식(14.0%)이 가장 많은 것으로 나타났다. 결 론 : 재발성 폐렴에 대한 접근에 있어서 폐렴 자체에 대한 치료와 더불어 선행원인을 찾아보는 것이 중요한데, 본 연구결과 세기관지염 및 기관지 천식이 가장 흔한 선행 질환이 었음을 알 수 있어 이에 대한 검사가 반드시 필요할 것으로 사료된다. N/A

내시경을 이용한 경흉강 늑막외측 접근 흉추 추간판 절제술 3례 - 수술수기 증례보고 -

이상호,전상협,최종렬,이호연,정병주,임상락,Lee, Sang-Ho,Jeon, Sang-Hyeop,Choi, Jong-Yeul,Lee, Ho-Yeon,Jung, Byung-Joo,Lim, Sang-Rak 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.12

Microsurgical transthoracic extrapleural approach for thoracic discectomy in three cases were modified and simplified in order to achieve better exposure of ventral extradural space than posterolateral extrapleural(lateral extracavitary) approach and less pulmonary complications than transthoracic transpleural approach. These approaches were optimized by microscope and video-assistance. Surgery was followed by clinical improvement in all patients. The results of treatment seem to support the use of these modified techniques as adequate surgical treatment of thoracic disc herniations without any complications.

채도와 명암비 개선을 통한 화질 향상 기법

박규희(Gyu-Hee Park),정병주(Byoung-Ju Jung),윤종호(Jong-Ho Yun),조화현(Hwa-Hyun Cho),최명렬(Myung-Ryul Choi) 대한전자공학회 2007 대한전자공학회 학술대회 Vol.2007 No.7

In this paper, an image enhancement method by saturation and contrast improvement is proposed. Histogram equalization with color difference makes higher contrast. By generating saturation amplification ratio with color difference, the saturation improves effectively. The experimental results show that the proposed algorithm has higher contrast and more natural - look than the conventional methods.