인공사육장에서 패혈증으로 집단폐사한 북방산개구리의 증례 보고

정여진 ( Yeo Jin Jeong ),김종택 ( Jong Taek Kim ),서국현 ( Guk Hyun Suh ) 한국동물위생학회 2014 韓國家畜衛生學會誌 Vol.37 No.3

Frog culture industry is not yet familiar but has much potential. Generally, in farm, the population density is higher than that of in nature and frog farm is not the exception. But when population density is high, it can easily leads to stressful condition, poor sanitation. When a disease occur, it is a primary factor that makes the population more susceptible and the results more grave. Because of severe Rhabditoidea- helminth infection and subsequent bacterial septicemia, 50¡­70% of the total population had been died in a farm in Jeong-sun in Gangwon-do and Chungju in Chungcheongbuk-do from late June, 2012 to September, 2012. Diseased frogs showed ruptured lung, bloody ascites, liver discoloration, myocardium weakness, congested kidney, microcytic anemia and so on. Enterobacteriacea, Citrobacter.sp, Cupriavidus metallidurans, Acinetobacter.sp were isolated as major bacterium that had caused septicemia in frogs. Among isolated bacterium, Cupriavidus metallidurans, Ewingella americana, Shewanella aquimarina and Pseudoalteromonas sp. have not reported as potential pathogens in frogs before. It is a good example that severe helminth infection in frogs can lead to secondary infection of bacteria.

경막 내 colistimethate 투여로 치료한 다제 내성 cinetobacter baumannii 뇌실염

홍유아,유진홍,김진진,모은영,안건희,정희경,김진석,이현정,정미향,윤승배 대한감염학회 2009 감염과 화학요법 Vol.41 No.4

Acinetobacter species is a non-fermentative aerobic gram-negative coccobacillus that is an important pathogen found in nosocomial infections. Recently, multi-drug resistant Acinetobacter baumannii (MDR-AB) infections have been increasing and pose a serious problem. Most such infections present as bacteremia, pneumonia, or a wound infection; however, CNS infections are very rare. We herein present a case of ventriculitis caused by MDR-AB in a 37-year old man after a neurosurgical intervention. The patient was successfully treated with intrathecal colistimethate.

예술사조와 패션과의 Parallelism에 관한 연구 : Focusing on Modernism and the Flapper Look 모더니즘과 플래퍼 룩을 중심으로

정현숙,김진구 服飾文化學會 1995 服飾文化硏究 Vol.3 No.2

This paper analyzes the parallelism between the art trend and the fashion. As a representative case, we consider the Modernism and the Flapper look. The Modernism rejected the tradition of the past and pursued something new. This trend was in parallel with the fashion called flapper look which was against the tradition and made a drastic change. The factors which represent the spirit of the age of the Modernism are the simplicity, the rejection of the tradition, the individualism and the subfectivity, the functionalism, the fragmetnation of the self, and the straight line, We discuss the fashion style of the flapper look in terms of these factors.

동종 골수이식 후 만성 이식편대숙주질환과 동반되어 신증후군으로 발현된 IgA 신병증 1예

정철권,김현수,박준성,정성현,조도연,최진혁,남동기,임호영,김명성,신규태,임현이,김효철 대한조혈모세포이식학회 1999 대한조혈모세포이식학회지 Vol.4 No.2

동종 골수이식 후 발생하는 신기능부전은 원인이 다양하여 감별에 어려움이 있다. 만성 GVHD는 흉선의 기능저하에 따른 면역관용의 실패로 발생되는 자가면역현상에 의해 발생되는 것으로 알려져 있으며 드물게 신장을 침범하여 신증후군을 일으키기도 한다. CaA의 용량을 줄이거나 투약중지 후 발생한 만성 GVHD에 동반된 신증후군의 경우 조기에 신조직검사를 시행하여 감별진단하고 CsA의 용량을 증량하거나 재투약하여 좋은 치료 결과를 보일 것으로 기대된다. 저자들은 문헌고찰을 통해 동종 골수이식 후 발생된 신증후군이 유사한 임상양상을 보이며 발생기전에 만성 GVHD와 자가면역현상이 연관되어 있음을 확인하였으며 동종 골수이식 후 신증후군의 임상양상을 보이는 환자에서 병리조직학적으로 lgA 신병증을 진단하고 이러한 lgA 신병증이 발생기전에 만성 GVHD와 자가 면역현상이 연관되어 있을 가능성을 최초로 확인하였으며 CsA를 이용하여 성공적으로 치료한 경험을 하였기에 보고하는 바이다. Renal insufficiency is occasionally encountered in allogeneic bone marrow transplantation and its cause is difficult to ascertain. Chronic graft-versus-host disease (GVHD) related to thymic dysfunction is immune-mediated and involves autoreactivity of T-lymphocytes derived from donor marrow to recipient's major histocompatibility complex(MHC) minor antigens. The clinical mainifestations of chronic GVHD are similar to those of autoimmune disease but kidney involvement is rare. Few cases of nephrotic syndrome with membranous nephropathy or minimal change nephrotic syndrome have been reported to be associated with chronic GVHD in allogeneic bone marrow transplant recipient especially after cyclosporine A(CsA) withdrawal, and these cases have responded well to CsA. Therefore, it is prudent to differentiate the cause of post-transplant renal insufficiency using renal biopsy and to start CsA in a case of nephrotic syndrome associated with chronic GVHD as early as possible. We report a case who had a massive proteinuria during the post-allogeneic marrow transplantation period. The cause of nephrotic syndrome was diagnosed as IgA nephropathy by renal biopsy. The patient was successfully treated with reintroduction of CsA.

소화성 궤양 환자에 대한Lansoprazole의 치료 효과

정현용,김진희 최신의학사 1997 最新醫學 Vol.40 No.6

고주파수 근사 이론을 이용한 결함으로부터의 초음파 산란장 해석

정현조,김진호 한국비파괴검사학회 2000 한국비파괴검사학회지 Vol.20 No.2

본 논문에서는 체적형 결함과 균열형 결함에 대한 초음파 산란 현상을 모델링하기 위한 두 가지 이론을 설명하였다. 동탄성 Kirchhoff 근사 (EKA)와 기하학적 회절이론 (GTD)이 각각 원주형 기공과 반무한 균열에 적용되었다. 이 두 이론은 고주파수 근사법으로 알려져 있다. 모델 결함들에 평면파가 입사하는 경우의 2차원 동탄성 산란 문제를 고려하였으며 산란장을 반사계수와 회절계수의 항으로 구하였다. 원거리에서 산란파의 변위에 대한 입사파 변위의 비를 관찰 방향의 함수로 구했으며 그 결과를 경계요소법과 비교하였다. This paper describes two different theories used to model the scattering of ultrasound by a volumetric flaw and a crack-like flaw. The elastodynamic Kirchhoff approximation (EKA) and the geometrical theory of diffraction(GTD) are applied respectively to a cylindrical cavity and a semi-infinite crack. These methods are known as high frequency approximations. The 2-D elastodynamic scattering problems of a plane wave incident on these model defects are considered and the scattered fields are expressed in terms of the reflection and diffraction coefficients. The ratio of the scattered far field amplitude to the incident wave amplitude is computed as a function of the angular location and compared with the boundary element solutions.

古代哲學思想이 東醫病理學에 미친 影響

鄭遇悅,李鎭弘,鄭鉉雨 대한동의병리학회 1997 동의생리병리학회지 Vol.11 No.2

學問은 어느시대를 막론하고 그 胎動當時의 時代的·社會的·政治的·思想的 背景속에서 발전한다. 韓醫學 또한 이러한 背景속에서 발전되었다. 醫學은 환자의 질병을 치료하기 위한 학문으로 인체의 陰陽平衡狀態를 建康이라 정의한다면 疾病이란 인체의 陰陽失調(陰陽偏盛偏衰)라 말할 수 있다. 이러한 疾病을 유발시키는 원인과 그 원인으로 인하여 인체에 나타나는 각종 症狀들에 대 病理機轉을 밝히기 위해서는 韓醫學의 胎動當時의 배경들을 연구할 필요성이 있다하겠다. 그리하여 《黃帝內徑》이 著述되기 前 古代 哲學思想이 韓醫學 理論定立-東醫病理學-에 어떠한 영향을 미쳤는가를 고찰하기 위하여 현재 출간되고 있는 韓醫學 서적을 중심으로 고대 서적들을 참고하여 陰陽五行論과 精氣神論의 형성과정을 살펴보았다. 그 결과 古代 哲學思想인 敬天崇祖思想과 陰陽五行思想, 精氣神學思想들이 그 시대의 學術的 思想을 반영하듯 韓醫學에서도 역시 主流를 이루고 있었고, 이를 바탕으로 病因論도 고찰할 수 있었다. 즉, 韓醫學의 認識方法인 由果析因ㆍ類比推理ㆍ以象測臟 및 以表測裡의 方法을 통하여 疾病의 原因과 病理機轉등을 밝혔는데, 이것이 바로 그 時代的ㆍ學術的 背景에 따른 것임을 알 수 있었다. Because a time, society, politics, thought bring about effect learning, formation of oriental medicine is formed this background also, Before《Nae-Kyung》was written to study numerous effect antiquity philosophically on oriental medicine pathology investigated books from antiquity to presently. The result were as follows. 1. Before the Chroicles of Lu witch docters acted. 2. In the Chroicles of Lu, philosophically were "the Uem-Yang-O-Haeng theory", "Jeong-Chi-Shin theory" and "Chen-Yin-Shang-Ueong theory" etc. 3. This theories were effected formation of oriental medicine(the cause of a disease, course of disease, pathologic change, therapy etc)

초음파 센서를 활용한 이륜차 사각지대경보시스템 연구

심정현,정희철,이상혁,김우진,이상욱 순천향대학교 산업기술연구소 2022 순천향 산업기술연구소논문집 Vol.28 No.2

The purpose of this paper is to prevent driver from accidents by effectively notifying the driver blind spot warning in a short distance such as a narrow alley when using a two-wheeled vehicle. It is easy to see that two-wheeled vehicles are more fatal in the event of an accident. We analyzed and researched a safety warning device in low-speed driving to identify critical factors for drivers in two-wheeled vehicle driving, and to identify areas that can be improved. Based on the analysis and research, an experiment was conducted and a warning system was applied to the manufactured motorcycle.

金銀花 및 魚腥草가 人體 癌細胞柱에 미치는 影響

陳千植,崔政和,鄭鉉雨 대한동의병리학회 1996 동의생리병리학회지 Vol.10 No.1

국내 사망률 가장 높은 비율을 차지하고 있는 惡性腫瘍에 대하여 국내외적으로 다양하게 연구되고 있다. 그러나 아직까지도 腫瘍을 치료하기 위하여 手術治療·放射線治療·免疫治療·化學治療등의 많은 치료법을 개발하고, 또한 실험실 및 임상에서 많은 연구보고가 이루어지고 있지만 腫瘍의 치료원칙 및 치료약물에 대해서 미흡한 것이 국내의 현실이다. 일반적으로 抗癌劑를 이용한 化學治療등이 사용되고 있지만 이에 따른 副作用이 많아 본 연구자들은 抗癌劑와 韓藥材를 倂用投與하여 副作用을 최소화하고, 이에 따라 韓藥材가 正常細胞에 어떠한 영향을 미치고 , 癌腫細胞에는 어떠한 영향을 미치는가에 대하여 관찰한 결과 有意性이 있어 보고하게 되었다. 淸熱作用이 金銀花와 魚腥草를 인체의 皮膚癌細胞인 A431 細胞, 子宮癌細胞인 HeLa 細胞, 急性白血病細胞인 MOLT-4 細胞, 慢性骨髓性白血病細胞인 K562 細胞에 대한 細胞毒性과 抗癌劑인 mitomycin C와 倂用처리결과를 MTT assay를 통하여 관찰하였다. 또한 正常細胞에 대한 細胞毒性을 검색하기 위하여 마우스 섬유아세포(Balb/c3T3), 마우스 胸線 및 腥臟細胞, human lymphocyte에 미치는 細胞毒性을 검토하였다. 魚腥草는 慢性骨髓性白血病細胞柱에 직접적인 細胞毒性을 나타냈고, mitomycin C와 倂用 處理時 細胞毒性을 증가시켰으며, 마우스 섬유아細胞인 Balb/c 3T3 細胞의 增殖을 억제시켰다. 또한 金銀花는 마우스 胸線細胞의 增殖을 촉진시켰고, human lymphocyte의 增殖을 촉진시켰으며, 金銀花 및 魚腥草 모두는 마우스 腥臟細胞의 增殖을 촉진시켰다. The purpose of this research was to investigate effect of water extract of Flos Lonicerae and Herba Houttuyniae on the proliferation of human cancer cell-lines. The effects of Flos Lonicerae and Herba Houttyniae on the proliferation of A431, HeLa, MOLT-4, K562 cells, Balb/c 3T3 cells, mouse thymocytes, splenocytes and human lymphocytes were estimated by MTT colorimetric assay. 1. Flos Lonicerae and Herba Houttuyniae inhibited the proliferation of K562 cells. 2. The cytotoxicity of mitomycin C on K562 cells was decreased by the combination of Herba Houttuyniae. 3. Herba Houttuyniae inhibited the proliferation of Balb/c 3T3 cells. 4. Flos Lonicerae stimulated the proliferation of thymocytes. 5. Flos Lonicerae and Herba Houttuyniae stimulated the proliferation of splenocytes. 6. Flos Lonicerae stimulated the proliferation of human lymphocytes.

아크릴 부목을 이용한 하악골 골절의 새로운 치료법

정두성,박재현,김진환,최준 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.3

As modern society becomes increasingly complex, there has been a steady increase in violence, as well as in automobile and industrial accidents. This has resulted in an increased incidence of facial injuries, including mandibular fractures. Many methods have been advocated to achieve reestablishment of normal feature and function. The choice generally depends upon such factors as location of the fractures, displacements, status of the dentition and favorability of the fracture line. Many cases of mandibular fracture are treated by intermaxillay fixation using an arch bar or bite block(acrylic splint)for rapid bone union and minimal displacement. However, there had been some problems, such as discomfort to patients, limitation to eating and weight loss, poor oral hygiene, and temporomandibular joint ankylosis. As a consequence, we have modified the shape of the acrylic splint and method of fixation for circum-mandibular fixation instead of intermaxillary fixation. Acrylic splints are rigid, strong, easily adjusted and repaired, translucent, lightweight and well tolerated by the oral mucosa. The splints are properly secured to each tooth and bind all the teeth together as a single unit. Authors have used modified acrylic splints as tools of circum-mandibular fixation in 12 cases of mandibular symphysis and body fracture from May 1997 to August 1998, achieving the results of very good occlusal relationship, oral hygiene and comfort to patients.