18–30세 사이에 발생하는 뇌경색의 특징, 다기관 레지스트리 연구

장윤경,송태진,김용재,허지회,이경열,김영은,장민욱,조수진,강석윤 이화여자대학교 의과학연구소 2017 EMJ (Ewha medical journal) Vol.40 No.3

Objectives: Although there have been several reports that described characteristics for young age stroke, information regarding very young age (18–30 years old) has been limited. We aimed to analyze demographic factors, stroke subtype, and 3-month outcome in acute ischemic stroke patient who have relatively very young age in multicenter stroke registry. Methods: We evaluated all 122 (7.1%) consecutive acute ischemic stroke (within 7 days after symptom onset) patients aged 18 to 30 from 17,144 patients who registered in multicenter prospective stroke registry, 1997 to 2012. Etiology was classified by Trial of Org 10172 in Acute Stroke Treatment criteria. Stroke severity was defined as National Institutes of Health Stroke Scale (NIHSS) and stroke outcome was defined by modified Rankin scale (mRS) at 3 months after index stroke. Results: The mean age of all included patients was 25.1±3.7 years and 76 patients (62.2%) were male. The median NIHSS at admission was 4. Considering stroke subtype, 37 patients (30.3%) had stroke of other determined etiology (SOD), 37 (30.3%) had undetermined negative evaluation (UN) and 31 (25.4%) had cardioembolism (CE) were frequently noted. After adjusting age, sex and variables which had P<0.1 in univariable analysis (NIHSS and stroke subtype), CE stroke subtype (odds ratio, 4.68; 95% confidence interval, 1.42–15.48; P=0.011) were significantly associated with poor functional outcome (mRS≥3). Conclusion: In very young age ischemic stroke patients, SOD and UN stroke subtype were most common and CE stroke subtype was independently associated with poor discharge outcome.

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

엠보싱 알루미늄 판재의 기계적특성과 스프링백 평가 (제1보)

김영석(Kim, Young-Suk),조준행(Cho, Jun-Haeng),Van-Cuong Do,신동우(Do, Van-Cuong) 한국산학기술학회 2015 한국산학기술학회논문지 Vol.16 No.2

엠보싱된 알루미늄 판재는 표면적이 증가하여 방열효과가 뛰어나고 가공경화에 의해 굽힘강성이 증가하여 자동차 열차단기에 널리 사용된다. 하지만 판재의 특성상 주름발생률이 높아 프레스 성형에 많은 제약이 따른다. 본 연구에서는 3차원 구조 알루미늄 판재의 프레스 성형성 평가를 위한 기초연구로 3차원 구조 엠보싱 콘 형상 판재의 기계적특성을 평가 하고 굽힘실험을 통해 프레스 가공 후 발생하는 스프링백을 정량적으로 평가하였다. 엠보싱 판재는 패턴의 방향에 따라 인장특성이 상이하다. 특히 평행 엠보싱 시편의 경우 항복응력이 감소하며 대각 엠보싱 시편의 경우 항복응력이 증가하게 되고 영률의 감소가 크게 나타난다. 그 결과 굽힘 성형가공 후에 스프링 백에 영향을 미친다. Embossed aluminum sheets were been used in heat insulation purpose for automative exhaust parts because of increasing their surface areas and stiffness reinforcement. However, there are many restrictions because of high rate of wrinkle occurrence on press working. We have performed the tensile and bending tests for embossed sheets to clarity its mechanical properties and springback characteristics. Embossed aluminum sheets showed a different flow stress after plastic yielding due to flattening the embossed cone shape. Above all, yield stress of parallel embossed specimen decreases while its diagonal one increases and the decrease of young’s modulus in the embossed sheets contributes to the increase of springback amount.

양파(Allium cepa L.) 추출물이 Tyrosinase 유전자 발현에 미치는 효과

조남철,윤연희,이혜진,손현정,김양경,최근희,나명석,조영권,이황희,진종언 한국식품영양학회 2001 韓國食品營養學會誌 Vol.14 No.3

Melanin 생성에 관여하는 tyrosinase 유전자의 발현을 억제하는 물질을 탐색하고자 tyrosinase promoter를 지닌 Bl6 mouse melanoma cell해 앙파 methanol 추출물을 처리한 바 양파 methanol 추풀물은 10.0㎍/ml, 100.0 ㎍/ml, 1.0 ㎎/ml의 농도에서 대조군에 비해서 약 15%, 23% 57%의 억제효과를 나타냈으며 세포생존율은 1.0 ㎍/ml, 10.0 ㎍/ml, I00.0 ㎍/ml, 1.0㎎/ml의 농도에서 약 126 %, 92%. 85%, 64%로서 세포독성이 낮게 나타났다. Ethyl acetate, butyl alcohol, 그리고 물 용매 분획물은 tyrosinase 유전자의 발현물 억제하는 효과가 없었지만 methylene chloride 용해 분획물은 10.0 ㎍/ml과 100.0 ㎍/ml의 농도에서 약 37%와 35%의 발현율을 나타냄으로서 대조군에 비해 크게 억제하였다. Onion(Allium cepa L,) extract by methanol repressed the expression of tyrosinase gene of B16 mouse melanoma cell containing tyrosinase promoter. 10.0 ㎍/ml, 100.0 ㎍/ml, 1.0 ㎎/ml of the extract repressed expression of tyrosinase gene about 15%, 23%, and 57%, respectively, compared with control. In the MTT assay, the same extract exhibited low cytotoxicity at 1.0 ㎍/ml, 10.0 ㎍/ml, 100.0 ㎍/ml, and 1.0 ㎎/ml, respectively. The fractions of ethyl acetate, butyl alcohol, and water did not showed the repressive effect on the expression of tyrosinase gene, but the fraction of methylene chloride repressed highly at 10.0 ㎍/ml and 100.0 ㎍/ml.

노인의 운동행위변화단계에 따른 변화과정, 의사결정평가, 자아효능감 및 주관적 건강지각

조영숙,이해정 성인간호학회 2003 성인간호학회지 Vol.15 No.2

The purpose of this study was to examine the differences of the process of change, decision making. Self-efficacy and perception of subjective health according to the stages of exercise behaviors suggested by transtheoretical medals among older adults. Method: The subjects consisted of 291 older adults. Trained research assistants interviewed the older adults using structured questionnaires. ANOVA analyses with post hoc test were used to examine the mean differences for each stage of exercise behavior using SPEE for windows. Result: The subjects were divided into five stages of exercise behavior: 24.4% pre-contemplation, 12.4% contemplation, 17.9% preparation, 12.4% action, 33.0% maintenance stage. There were significant differences in process of change, decision making, self-efficacy and exercise stage of change. ‘Self-liberation’ and ‘stimulus control’ were important strategies for intention of exercise, while ‘reinforcing management’ for the actual practice of exercise. ‘Self-liberation’ was an effective strategy to change older adults from pre-contemplation to preparation stage. Conclusion: For exercise intervention, older adults should be classified into groups according to their stages of exercise behaviors and provided effective individualized intervention depending on their stage.

Goldman's Algorithm을 이용한 비외상성 흉통 환자의 분석

조석진,유진현,김찬웅,어은경,정구영 대한응급의학회 1999 대한응급의학회지 Vol.10 No.4

Back ground : It is important to evaluate the patient presenting with non-traumatic chest pain in emergency department, and it is also difficult to classify appropriately. The purpose of this study is to predict probability of acute myocardial infarction(AMI) and assess the group for low probability of AMI that is target for observation-unit of chest pain in emergency department. Methods : A prospective, clinical study was performed from March 1998 to August 1998 at the department of emergency medicine, Ewha Womans University Mokdong hospital. We classified high-probability group and low-probability group of AMI according to Goldman's algorithm and then compared with the final diagnosis. Results : The study included 218 patients. 84 patients(39%) was the high-probability group and 134 patients(61%) was the low-probability group of AMI. As compared with final diagnosis, AMI was 47 patients(56%) among the high-probability group and 1 patient(0.7%) among the low-probability group. We observed sensitivity of 98%, specificity of 78% in predicting AMI. Conclusion : The classification according to Goldman's algorithm may be useful predictor of AMI and improve triage for emergency department patients with chest pain. It is also helpful for management of observation-unit of chest pain in emergency department.

脚筋力 및 몇몇 體力要因과 全身反應과의 相關關係에 關한 硏究

趙泳奭 全北大學校 師範大學 1980 사대논문집 Vol.6 No.-

The 47 students of sophomore in Jeonbug National University are selected as the subject of this study. This is aimed at presenting the factors to affect the whole body reaction time and making some data for reference in order to develop the reaction time. By means of while body reaction measuring device, the reaction time was measured, and from the measurements of leg strength, back strength, sargent jump. strength of abdominal muscle, the correlation was searched. The results of this study are as follows ; 1. The highest degree of correlation in all of the athletes, non-athlete, and girl students are shown between the whole body reaction time and the strength of abdominal muscle. 2. Leg strength, back strength, sargent jump are in little correlation with whole body reaction time. 3. The difference in whole body reaction time between athletes and non-athletes is not remarkable.

백서피부의 화상 손상에 따른 효소조직화학적 변화

조백현,김영길,허우회,최석현 大韓成形外科學會 1983 Archives of Plastic Surgery Vol.10 No.2

The purpose of this study was to investigate the sequential changes of enzyme activities in severely burned skin of rat at intervals of 2 hours, 8 hours, 1 day and 3 days by histochemical methods. The results obtained were as follows. 1. Acid phosphatase activity was found to be transient increase in dermis and mild decrease in epidermis, hair follicle and sebaceous gland at 2 hour after burning. The activity was not seen in skin after 8 hours. 2. Alkaline phosphatase was found to be decreased in blood vessel and dermal papillae of hair follicle at 2 hour after burning and then was progressively decreased after 8 hours. 3.α-naphtyl acetate esterase activity was found to be decreased in epidermis, dermis and hair follicle at 2 hours after burning and was not seen in skin after 8 hours. There was no significant changes in sebaceous gland after burning.

사다리꼴 핀에 대한 해석적 방법과 실험의 비교

조철현,한영민,강형석 江原大學校 産業技術硏究所 2005 産業技術硏究 Vol.25 No.A

A trapezoidal fin is analyzed by using one-dimensional analytic method. For two boundary conditions, the heat transfer rate is given instead of specified temperature at the fin base and heat conduction into the fin tip is equal to heat convection from the tip. Temperatures at three different points within the trapezoidal fin are measured by using experimental apparatus. A comparison of the temperature between one-dimensional analytic method and experimentation is made as a function of dimensionless fin length under both free convection and forced convection conditions. The ratio of heat loss from the fin tip surface to that through the fin base is presented as a function of dimensionless fin length and Biot number. One of results shows that the relative error increases as the air velocity increases for forced convection conditions.

복합열화환경하에서의 중성화 및 염화물이온 확산특성이 철근부식에 미치는 영향에 관한 실험적 연구

조봉석,장재봉,김재환,김용로,권영진,김무한 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

It is recognized that reinforcement corrosion is the main distress behind the present concern regarding concrete durability. In this study, to confirm corrosion of reinforced concrete due to permeability of carbonation and chloride ion affected by thickness of cover, kinds of surface coating, measured electric potential, ratio of corrosion area, weight reduction, corrosion velocity of steel bar under environment of complex deterioration. The results showed that an increase in age also decreases Carbonation velocity coefficients and increases Chloride ion diffusion coefficients. As well, an increase in age also increases corrosion of reinforcement due to permeability of carbonation and chloride ion. Corrosion of reinforcement by thickness of cover is superior to 10mm thick than 20mm thick. It showed that an increase in thickness of cover prevent steel bar from deteriorating due to permeability of carbonation and chloride ion. The results of this study showed that corrosion velocity was affected by thickness of cover, kinds of surface coating. data on the development of corrosion velocity made with none, organic B, organic A, inorganic B. and inorganic A is shown.