대장암 환자에서의 담즙 암태아성 항원(CEA)

김종우,박용태,정철운,권성원,장항석,손석우,안대호,이경포 대한대장항문학회 2000 Annals of Coloproctolgy Vol.16 No.6

상악궁 확장술을 통한 치료전,후 및 보정후 상악 구치부 변화에 관한 연구

박태서,이진우,차경석 대한치과교정학회 1997 대한치과교정학회지 Vol.27 No.1

치열궁의 크기와 폭경 변화에 대한 연구가 사용된 장치형태, 사용시기에 따라, 그리고 사용 목적에 따라 다양한 연구가 활발히 이루어져 왔다. 또한 Quad-helix도 선학들에게 관심의 대상이었으며 Quad-helix의 안정성과 장치 사용 전, 후에 대한 효과도 연구가 이루어졌다. 그러나 장치 사용에 대한 장기적인 효과에 대한 연구가 미흡하여 본 논문은 이 장치를 사용하여 치료한 환자의 치료 전, 후 및 보정후의 치열궁 변화에 대한 연구를 시행하여 Quad-helix사용 전, 후 구치부의 적응 양상을 연구함으로써 임상에서 Quad-helix를 통한 치료를 시행할 때 이 장치사용에 따른 효과 및 예후에 대하여 효과를 이해함으로써 교정치료에 도움을 주고자 연구를 시행하여 다음과 같은 결과를 얻었다. 1. Quadhelix를 사용한 교정치료시 상악 제 1 소구치와 제 1 대구치는 치료전과 치료 후 및 보정후에서 교두간 폭경의 증가를 보였고 제 2 소구치에서는 치료후와 보정후간에 유의성있는 증가를 보였다. 2. 상악 제 1 소구치와 제 1 대구치의 치축은 치료전과 치료후 그리고 보정후에서 협측 경사도가 유의하게 증가를 보였으며, 상악 제 2 소구치는 치료전과 치료후 및 치료전과 보정후 비교에서 설측 경사도가 유의하게 증가를 보였다. 3. 최대 풍융부 항목에서 상악 제 1, 2소구치는 치료전과 치료후의 비교에서 유의한 증가를, 제 1 대구치에서는 치료 전, 후, 및 보정후에 유의한 증가를 보였다. 4. 상악 제 1 대구치의 설면구 폭경은 치료전, 후 및 보정기간을 통하여 유의한 증가 를 보였고, 구개 높이는 치료전과 치료후 비교시 유의한 증가를 보였다. 5. 확장시킨 상악 치열궁은 회귀현상을 보이지 않고 안정적으로 유지되었다. The purpose of this study was to measure the changes of arch and dentition of maxillary posterior teeth before and after treatment and postretentios in patients treated with Quad-helix. Measurements and analysis were performed on study model with carlipers. Seventeen cases, eight boys and nine girls, were selected with average ages of 12.7 years. Mean retention period was 4 months, and mean wearing time was 127 days. The result were as follows 1. The interpremolar widths and intermolar width were significantly increased in maxillary first premolar and molar when compared between before and after treatment and postretention. The maxillary second premolar resulted in significant increase in interpremolar between after treatment and post retention. 2.The long axis of maxillary first premolar and first molar accompaning buccaltipping was significant increased before and after Tx and post retention. Significant increase of the lingual inclination of maxillary second premolar was obsered both in before and after Tx, and before Tx and post retention. 3.The distance between the height of tooth contour was significantly increased in the first and second premolar before and after Tx, and was significant increased in the first molar before and after Tx and post retention. 4.Intermolar width at the palatal groove was increased in before and after and after Tx. and post retention. The palatal depth was significant increased in before and after Tx. In conclusion, expansion of maxillary dental arch showed no relapse and results were stable retention.

수치해석을 통한 오븐건조 작업에서의 칼라 강판 온도예측

이태우,이경우,최민석,이덕재 대한금속재료학회 2004 대한금속·재료학회지 Vol.42 No.4

Paint coating process on steel sheet has to be carried out for producing prepainted steel sheet by continuous process. After coating process, drying processes are needed. Temperature control of oven system directly affects on the product quality, such as, a coherence of coating and state of surface. In this study, heat transfer coefficients were calculated by 3-dimensional heat flow analysis from hot wind of nozzle to steel sheet and values of PMT(Peak Metal Temperature) of steel sheets were predicted by adapting that value to 2-dimensional analysis and using the coefficients. Conditions of numerical analysis were obtained from orthogonal arrary which is known as Taguchi method. Coefficients of heat transfer coefficient equation were derived from the second order regression model. By comparing numerical analysis with experimental results, the accuracy of numerical analysis was verified. Moreover we analyzed the effect of various conditon of factors, such as velocity and thickness of steel sheet, temperature of hot wind and the type of steel sheet. (Received December 17, 2003)

가속수명실험을 이용한 케이블 절연재료의 수명특성에 관한 연구

남창우,이규철,박홍태,이태식,김경석 울산대학교 1997 공학연구논문집 Vol.28 No.1

본 연구는 고체절연재료의 수명예측의 일환으로서 가속수명실험을 통해 얻은 수명데이터의 통계학적 처리방법과 복합 스트레스와 수명과의 상호관계를 규명하기 위한 수명모델을 제시하고 있다. 가속수명실험을 통해 얻는 수명데이터는 와이블분포에 적용하고, 최소자승법과 최우추정법을 이용하여 와이블분포함수의 모수를 추정하였다. 또한 제시된 수명모델의 상수를 추정하여 복합스트레스와의 관계를 규명함으로써 수명모델의 타당성을 입증하였다. 추정결과, 주위온도와 인가전압이 상승함에 따라 수명은 현저히 짧아지고, 수명모델의 상수는 복합스트레스에 크게 의존하는 것으로 나타난다. 따라서 본 연구에서 제시된 수명모델은 고체절연재료의 수명을 나타내는데 적당한 것으로 나타났다. This paper suggests the statistic method for a lifetime estimation of solid insulating materials using the data obtained from accelerated aging test has been performed to obtain the lifetime data. The multi-stress including thermal and electrical stress has been applied to accelerate the degradation of insulating materials. The Weibull Cumulative Distribution Function has been used to treat statistically the lifetime data. Using the lifetime model of this study, we estimated the lifetime constants to show the relationship between the lifetime and the applied multi-stress. It has been shown that the lifetime model agrees well with the lifetime of solid insulating materials.

구조방정식모형의 이론 및 적용

김석우,최태진 부산대학교 사범대학 1998 교사교육연구 Vol.36 No.-

The purpose of this study aims to review the theoretical perspective and an applied example of structural equation model(SEM). Structural equation model consists of two parts, which are measurement model and structural model. The measurement model describes the causal link between latent variable and observed variables. The structural model encompasses the structural equations that summarize the relationships among latent variables. The analytical procedures for testing the theoretical model in the structural equation model are as follows: model specification, model identification, parameter estimation, model evaluation, and model modification via goodness of fit index. Regression models, path models, and factor models can be incorporated into the common framework of the structural equation model. However, even with the power and flexibility of the structural equation model, a number of limitations still remain, which are the sample size, the random sampling of data, distribution and characteristic of observed variables, etc.

우리나라에서 분리되는 Haemophilus influenzae의 9종 항균제에 대한 시험관내 감수성

장우현,최명식,석종성,정윤섭,서진태 대한화학요법학회 1989 대한화학요법학회지 Vol.7 No.2

To assess the occurrence of antimicrobial resistance among clinical isolates of H. influenzae in Korea, a total of 238 isolates were tested for their in vitro susceptibitlity to ampicillin and cefaclor by disc diffusion and 105 isolates were tested against nine antimicrobial agents-by the agar dilution method recommended by NCCLS. The antimicrobial agents sued for testing were ampicillin (Sigma A-9518, U.S.S.), cefaclor (Daewoong Lilly, Korea), cephalexin (Sigma C-4895, U.S.A.), cephradine (Sigma C-8395, U.S.A.), cephalothin (Sigma C-4520, U.S.A.), cefadroxil (Sigma C-7020, U.S.A.), erythromycin (Sigma E-6376, U.S.A.), teracycline (Sigma T-3383, U.S.A.) and cefatrizine (Dong-A Pharmaceutical Co., Korea). The isolation rate of H. influenzae from various clinical samples was 18.9%. Using the disc diffusion test, the resisant rates to ampicillin and cefaclor were shown to be 21.9% and 3.4%, respectively. Among the 52 ampicillin-resistant strains, 42 were susceptible to cefaclor (80.8%), and only two strains wre resistant. The MIS_(s) of ampicillin ranged from <0.125 ㎍/㎖ to >128 ㎍/㎖, and its MIC_(90) was 1 ㎍/㎖. Ampicillin showed the lowst MIC_(90) among the tested antivicrobial agents. The MIC_(90) of the tested cephalosporins ranged from 9.2㎍/㎖ to > 128. Among them, cefaclor showed the lowest MIC_(90) and its MIC_(90) was 9.2 ㎍/㎖. The MIC_(90) of tetracycline and erythromycin were 2.5 ㎍/㎖ and 14.4 ㎍/㎖, respectively. By the MIC, the resistant for ampicillin, cefalor, cephalexin, cephracine, cephalothin, cefadroxil, erythromycin, tetracycline and cefatrizine were 9.5%, 1.9%, 61.9%, 76.2%, 3.8%, 68.6%, 65.7%, 13.3% and 5.7%, respectively. There was no evidence that the MIC_(s) of cefaclor for the ampicillin-resistant strains differed significantly from those of cefaclor obtained with the ampicillin-susceptible strains. Except two islates, all of the multiple-esistant strains of H. influenzae were suceptible to cefaclor.

임상교정 교육용 멀티미디어 데이터베이스 웹서버 구축에 관한 연구

박재우,이종기,장영일,남동석,김명기,양원식,김태우,백승학 대한치과교정학회 2000 대한치과교정학회지 Vol.30 No.2

본 연구는 인터넷상의 가상공간에 다양한 자료로 구성된 환자 증례를 통해, 교정을 배우고자 하는 임상의나 학생들의 교육에 필요한 멀티미디어 데이터베이스를 구축하기 위한 것이다. 이러한 시스템을 구현하기 위해서는 이미지 자료의 처리, computer network를 통한 빠른 정보처리 기능, 진단 분석법의 개발, 데이터베이스의 구축 기술, 데이터베이스와 인터넷과의 연계, 증례를 통한 교육방법론과 같은 기술적 문제점들이 있다. 진단과 치료계획을 위한 분석은 모델 분석과 두부방사선 사진분석으로 나누어 제공하였다. 모델분석법은 arch length discrepancy와 Bolton tooth ratio를 환자 정보란에 제공하였다. 두부방사선 사진분석은 초진란에 제공하였다. Cephalometric analysis ver 2.0과 Power Ceph pro 3.3.5를 이용하여 Tweed, Steiner, Jarabak분석법 등을 제공하였으나, 본문에서는 주로 Kim's analysis와 몇 가지 계측치를 추가하여 설명하였고, 나머지는 tracing란에서 제시하였다. 또한 치료 종료 후나 보정란에서 치료 전, 후의 두부방사선 사진을 중첩해서 보여줌으로써 치료에 의한 효과를 직접 볼 수 있도록 하였다. The Objective of this research was to construct the multimedia database system that was necessary for the education of the practitioners and the students. To establish this system, there were technical problems as follows : 1) The processing of the images, 2) The rapid processing of the information with the computer network, 3) The development of diagnosis tools, 4) The technique to establish the database system, 5) The link between the database system and the internet, and 6) The method to educate through many cases. The analysis for diagnosis and treatment planning were provided as two parts : model analysis and cephalometric analysis. As a model analysis, arch length discrepancy and Bolton tooth ratio were provided for the part of patient information. Cephalometric analyses were provided in the part of initial diagnosis. The Cephalometric analysis ver 2.0 and the PowerCeph pro 3.3.5 were used to show Tweed, Steiner and Jarabak analysis. In the main part, Kim's analysis and some measurements were added. In the post-treatment or retention part, we show the superimposition of the cephalometrics with which you can find the effectiveness of the various orthodontic treatment. The address of this home page is "http://damis.snu.ac.kr/orthodontics"

국고 영세 사업장의 안전관리 실태 조사 분석

金炳錫,李泰宇 충주대 산업과학기술연구소 1996 産業科學論文集 Vol.4 No.-

Even though the industrial accident rate of Korea in 1995 was 0.99, most of industrial accident had occurred at small and medium enterprise which employed under 30 workers. Korea Industrial Safety Association have taken care of some of small size enterprise which occurred over one accident at previous year issued by korea government. on this study, the actual condition of industrial accident is investigated, analyzed. Finally, we present several countermove.

매크로/마이크로 레벨 볼트 결합 구조물에서의 실험적/해석적 방법을 통한 시스템 특성 비교

김봉석,이성민,이문구,이수훈,Jun Ni,송준엽,이창우,하태호 한국공작기계학회 2006 한국공작기계학회 추계학술대회논문집 Vol.2006 No.-

As the micro technology and miniaturization of a structure and component in the last couple of decades have been concretely realized, the understanding of structural and dynamic characteristics and prediction of dynamic behavior are indispensable to the miniaturized structures and micro machines. This paper shows the effect of dynamic characteristics in bolt-jointed structures by comparing natural frequencies and mode shapes between macro and micro-scale beams through experimental modal analysis and finite element analysis with a1 8 test models by materials, by size, and by joining condition; that is, SS41 and A16061-T651, micro and macro, and monolithic beam and bolt-jointed beam.

그람양성구균에 대한 Teicoplanin과 Vancomycin의 시험관내 항균력

최태열,김경숙,전용관,서일혜,김정욱,이웅수,안정열,김홍석,정재용,최효선,김덕언,유진우 대한감염학회 1994 감염 Vol.26 No.1

An increasing frequency of methicillin resistant S. aureus(MRSA), methicillin resistant coagulase negative staphylococci(MRCNS) and Enterococcal infection have been observed in recent years. Teicoplanin is a new glycopeptide antibiotic obstained from the Actinoplanes teicomycetius. The molecular structure and spectrum of antimicrobial activity of teicoplanin is simillar to those of vancomycin, and has been reported to have an excellent in vitro and in vivo effect against various gram-positive infections. Therefore, we evaluated the in vitor susceptibility of gram positive cocci, such as, S. aureus, coagulase negative Staphylococci(CNS), and Enterococci to teicoplanin and vancomycin. The total 253 strains consisted of MSSA(40), MRSA(53), MSCNS(47), MRCNS(48), and Enterococci(65). They were assayed by disc diffusion and agar dilution. During the study, 57% of S. aureus and 49% of CNS showed resistance to methicillin. The inhibitory diameter of teicoplanin was 15-20mm in MSSA, 12-19mm in MRSA, 13-24mm in MSCNS, 11-23mm in MRCNS, and 15-22mm in Enterococci respectively, and showed sensitivity in all but 8 strains(3.2%). The range of the minimum inhibitory concentration (MIC) of teicoplanin to MSSA, MRSA, MSCNS, MRCNS and Enterococci were 9.12-2.0㎍/ml, 0.25-2.0㎍/ml, & 0.25-32㎍/ml, 0.12-1.0㎍/ml respectively. One case of S. haemolyticus was resistant to teicoplanin (32㎍/ml) by the agar dilution method. Eight minor (3.2%) and one major(0.4%) error was observed when the MIC and disk diffusion data were correlated with teicoplanin. As for vancomycin the inhibitory diameter was 17-21mm in MSSA, 15-21mm in MRSA, 18-26mm in MSCNS, 18-25mm in MRCNS, and 16-22mm in Enterococci respectively. The range of the MIC of vancomycin to MSSA, MRSA, MSCNS, MRCNS, and Enterococci were 0.25-1.0㎍/ml, 0.25-4.0㎍/ml, 0.5-2.0㎍/ml and 0.5-2.0㎍/ml respectively. One minor error (0.4%) was seen with the vancomycin disk. The MIC90 of MSSA and MRSA exhibited the same results in teicoplanin (1.0㎍/ml, 1.0㎍/ml), and vancomycin(2.0㎍/ml, 2.0㎍/ml). MSCNS and MRCNS exhibited greater MIC90 with teicoplanin(4.0㎍/ml, 8.0㎍/ml) than vancomycin(2.0㎍/ml, 2.0㎍/ml). Incontrase Enterococci were more susceptible to teicoplanin(0.5㎍/ml) than to vancomucin (2.0㎍/ml). Results from this analysis indicated that both teicoplanin and vancomycin were very excellent for gram positive infections, especially those resistant to methicillin.