전정기능검사에서 정상소견을 보이는 어지러운 환자들의 임상적 특징

정원호,방은국,홍성화,이치규,이현석 대한평형의학회 2002 Research in Vestibular Science Vol.1 No.2

인체 자궁암 세포에서 천연 성분이 P-당단백질의 활성에 미치는 영향

정수연,고은정,김나형,성민경,장정옥,이화정 이화여자대학교 약학연구소 2005 藥學硏究論文集 Vol.- No.15

Multidrug resistance (MDR) of cancer cells is, at least in part, associated with the overexpression of P-gly-coprotein (P-gp). Many studies hve demonstrated that natural compounds obtained from fruits, vegetables, teas and medicinal plants may modulate P-gp activity. The objective of the present investigation was to examine the effect of seven natural compounds on the P-gp activity in human uterine sarcoma cell line, MES-SA/DX5. Daunomycin uptake was significantly increased by biochanin A and silymarin (p<0.0001) whereas it was reduced by morin (p<0.01). The efflux of daunomycin from the cells was significantly inhibited by biochanin A, morin, cephalotaxine, berberine (p<0.05) and silymarin (p<0.0001). Biochanin A, berberine and silymarin significantly decreased IC_(50) value of daunomycin (p<0.05) while morin increased it (p<0.05). These results suggest that some natural compounds such as biochanin A and silymarin may inhibit P-gp funciton and can by developed as MDR reversing agents to improve the efficacy of chemotherapeutic drugs when administered concomitantly.

NaCl이 보리(Hordeum vulgare L.) 잎의 엽록소 형광에 미치는 영향

정화숙,임영진,박강은,박신영 한국환경과학회 2004 한국환경과학회지 Vol.13 No.12

This study was conducted to investigate the changes of chlorophyll contents and chlorophyll fluorescence in barley(Hordeum vulgare L.) 7 day old seedling treated with 0.2M, 0.4M, 0.6M, 0.8M, and 1.0M NaCl concentration containing Hepes buffer(pH 7.5). Barley was affected by NaCl treatment. The chlorophyll a, b and carotenoid of barley decreased with an increase in NaCl concentration. However, chlorophyll a, b and carotenoid of barley were not greatly influenced by o.8M and 1.0M NaCl. Fv, Fv/Fm and qP were gradually decreased by higher concentration of NaCl. qP, qNP, qR and qE were gradually decreased by 6hr. During barley chloroplast was development NaCl affected chlorophyll synthesis than photosynthetic activity. Whereas barley seedling leaves were more influenced photosynthetic activity than chlorophyll contents by NaCl.

생약성분 항암제 Tianxian의 흡수동태에 관한 연구

양은정,김원배,심창구,이민화,정석재 서울대학교 1995 藥學論文集 Vol.20 No.-

발효 온도와 시간 조합을 달리한 총각김치의 품질 특성

강정화,강선희,안은숙,정희종 한국식생활문화학회 2003 韓國食生活文化學會誌 Vol.18 No.6

To determine the conditions of the fermentation and storage for Chonggak kimchi refrigerator, prepared Chonggak kimchi took into kimchi refrigerators which were controlled at four different modes of the fermented temperature and time, and fermented and kept for 16 weeks. The pH in Chonggak kimchi fermented at 20℃ for 24 hours/stored at 01℃ dropped greater than all of kimchi fermented at other combinations, and the changes of pH at any combinations were not greater than those in Baechu kimchi, because pH in Chonggak kimchi did not dropped below 4.5. Acidities in Chonggak kimchi were greatly increased at higher temperature. The acidity in Chonggak kimchi during the first week of fermentation was lower than that in Baechu kimchi and then it was rather higher becuase of the addition of waxy rice paste. In texture, puncture force of Chonggak kimchi was decreased slowly until 8 weeks of fermentation and then did not changed much and the highest values showed in Chonggak kimchi stored directly at -1℃ without any fermentation. In sensory evaluation, the score for the carbonated flavor and the sourness were the highest in Chonggak kimchi fermented at 20℃ for 24 hours/stored at -1℃, but the lowest in Chonggak kimchi stored directly at -1℃ without any fermentation because of some undesirable flavors. The lowest hardness showed in Chonggak kimchi fermented at highest temperature and the best hardness was in Chonggak kimchi fermented at 5℃ for 3 days or 6 days/ stored at -1℃. The appearance was the best in Chonggak kimchi fermented at 20℃ for 24 hours/stored at -1℃ and the worst was in Chonggak kimchi stored directly at -1℃ without any fermentation. The overall acceptability of Chonggak kimchi fermented at 20℃ for 24 hours/stored at -1℃ was good after 4 weeks of fermentation, but in Chonggak kimchi fermented at 5℃ for 3 days or 6 days/stored at -1℃ it was food after 6 weeks. Total microbial counts in most of Chonggak kimchi were reached to a maximum number within 7 days, and then decreased similarly at all modes. Leuconostoc spp. and Lactobacillus spp. increased to maximum number of 1.48 10^(9) and 5.62 0^(9), respecively, in Chonggak kimchi fermented for 7 days. Yeast counts showed a increasing trend not depends on fermenting temperature and they were lower counts than those in Baschu kimchi. Waxy rice paste which added to Chonggak kimchi resulted in increasement of glucose as a carbon source and stimulated to reproduce the microbes in Chonggak kimchi.

미기상 수치모의를 위한 다층식생모델의 식생 파라메타가 바람에 미치는 영향

오은주,이화운,정용현 한국환경과학회 2003 한국환경과학회지 Vol.12 No.6

In order to make use of the protection effect against wind by the vegetation, it examined whether it should make what vegetation form and arrangement using the 2-dimensional non-hydrostatic model. When the foliage shielding factor increases, it becomes hard to take in protection effect against wind in a residential section. When it makes height of vegetation high, it becomes hard to take in protection effect against wind with height. In the comparison in the case where vegetation high is gradually made low toward wind-stream from a vegetation, and the case of making it low gradually, although former tends to receive the protection effect against wind by the vegetation, attenuation of wind velicity becomes large. In the comparison in the case where foliage shielding factor and distribution of density of leaf are gathered gradually toward wind-stream from a vegetation. It has been understood to evaluate to height the influence that the vegetation multi-layer model by which the heat revenue and expenditure in the direction of the vegetation height is considered is used, and to characterize the vegetation group by the parameter setting.

독거노인과 가족동거노인의 신체적 건강상태와 건강행위에 관한 연구

장은희,김후자,권경남,정귀애,김연화,이인혜 영남이공대학 2004 論文集 Vol.33 No.-

Purpose : The purpose of this study was to identify the physical health status and health behavior practice of in-home elderly in order to provide basic data for effective nursing intervention to promote health and quality of life. Method : The subjects for this study were 299 elderly persons in the D city. Data were collected by interview with questionnaires. Result : The ratio of chronic disease was higher for the elderly who live alone than the elderly who live with family. Arthritis was the most common chronic disease of the elderly in spite of the fact that either they live alone or live with family. The physical health status score of the elderly who live with family was statistically higher than the elderly who live alone. The health behavior score of the elderly who live with family was statistically higher than the elderly who live alone. Conclusion : To promote health behavior of the elderly, it is necessary to develop nursing intervention that considers sociocultural tradition and demographic character.

아동의 내적 동기 및 자기효능감과 창의성의 관계 : 성별과 연령을 중심으로

김은아,정옥분,정순화 이화여자대학교 교육과학연구소 2007 교육과학연구 Vol.38 No.2

The purpose of this study was to investigate the relationships betweenintrinsic motivation, self-efficacy, and creativity of children. The subjects of thisstudy consisted of 304 fourth, fifth, and sixth grade public elementary schoolstudents in Seoul, Korea. The data were analyzed by using frequencies,percentiles, means, standard deviations, Cronbach’s a, two-way ANOVAs,Pearson’s correlations, and a multiple regression analysis. The major findings of this study were as follows: (1) There were significantdifferences in intrinsic motivation, self-efficacy, and creativity in terms ofgender and grade. Girls had higher scores in intrinsic motivation, self-efficacy,and creativity. Also, intrinsic motivation, self-efficacy, and creativity scoresincreased with grade. (2) Intrinsic motivation and creativity, self-efficacy andcreativity are significantly correlated each other. (3) Gender, intrinsic motivation(task difficulty preference), and grade were the variables that significantlypredict creativity. These variables explained 12.3% of children’s creativity. 본 연구의 목적은 아동의 내적 동기 및 자기효능감과 창의성의 관계를 살펴보는 데 있다. 연구대상은 초등학교 4~6학년 아동 304명이며, 자료에 대한 분석은 빈도와 백분율, 이원분산분석, 상관분석, 다중회귀분석방법을 사용하였다. 연구결과 내적 동기, 자기효능감 그리고 창의성은 성별과 학년에 따라 유의한 차이가 있는 것으로 나타났다. 내적 동기, 자기효능감, 창의성 총점에서 남아보다는 여아의 점수가 더 높은 것으로 나타났다. 또한 내적 동기, 자기효능감 그리고 창의성은 학년에 따라 증가하는 것으로 나타났다. 아동의 내적 동기, 자기효능감,창의성 간에는 밀접한 관련이 있는 것으로 나타났으며, 특히, 아동의 내적 동기와 창의성은 유의한 상관이 있는 것으로 나타났다. 아동의 창의성을 예측하는 변인은 ‘성별’과 내적 동기의 하위 영역 중 하나인 ‘도전적 과제선호’ 그리고 ‘학년’으로, 이 세 변인들의 설명력은 12.3%로 나타났다.

Head-Space SPME에 의한 생체시료 중 메스암페타민류 분석(Ⅱ)

최화경,양원경,한은영,최상길,정희선 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

국균세포벽을 모델로 한 새로운 고정화담체의 개발

유은정,김종덕,송상호,임현수,최명락,정규화 여수대학교 1997 論文集 Vol.11 No.2

The purpose of this investigation was to develop a new carrier using chitin and glucan as the model for Aspergillus oryzae cell wall. In case of the ratio of chitin and glucan(3/1), the activity of the immobilized protease had higher than that of model(chitin/glucan=1/3) and carriers were formed gel. In case of soluble chitin and glucan treated with calcium carbonate, there were a 1.8-fold increase in activity of immobilized protease compared with untreated chitin. The scanning electron microscope image showed that a pore size of this carrier had a homogenized pore size and a smooth surface.