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hanxionggao,최선일,문효,이세정,오건,진희구,오현지,김은진,김종욱,이부용,이옥환 한국식품영양과학회 2023 Journal of medicinal food Vol.26 No.4
Ecklonia stolonifera, belonging to the Laminariaceae family, is an edible widely distributed perennial brown marine alga that is rich in polyphenols. Dieckol, a bioactive component of the E. stolonifera extract (ESE), is a major phlorotannin compound found only in brown algae. This study aimed to evaluate the ability of ESE to inhibit lipid accumulation caused by oxidative stress in 3T3-L1 adipocytes and high-fat diet-fed obese ICR mice. We report that ESE-treated obese ICR mice, which were fed a high-fat diet, showed reduced whole-body and adipose tissue weights with improved plasma lipid profiles. In vitro and in vivo studies have indicated that ESE inhibited the expression of adipogenesis-related genes associated with fat accumulation through AMP-activated protein kinase activity and increased the expression of lipolysis-related genes. In addition, ESE reduced the expression of enzymes involved in reactive oxygen species (ROS) production and increased the expression of antioxidant enzymes, thereby reducing ROS levels. These findings suggest that ESE possesses strong antioxidant properties and inhibits oxidative stress-induced lipid accumulation by reducing ROS production during adipocyte generation.
Han, Xionggao,Choi, Sun-Il,Choi, Seung-Hyun,Cho, Bong-Yeon,Sim, Wan-Sup,Jang, Gill-Woong,Kwon, Hee-Yeon,Choi, Ye-Eun,Kim, Dan-Bi,Lee, Ok-Hwan The Korean Society of Food and Nutrition 2019 韓國食品營養學會誌 Vol.32 No.4
This study was to investigate the sorbic acid, benzoic acid and sulfur dioxide in commonly consumed beverages, snacks and instant ramens in Korea. A total of 150 food samples including 50 beverages, 50 snacks and 50 instant ramens were examined using the Korea Food Code method. Sorbic and benzoic acid were analyzed by the HPLC method, whereas sulfur dioxide was measured by Monnier-Williams method. Our results indicated that benzoic acid was detected in six beverages samples, and its concentration was in the range of 3.08-11.94 mg/kg. The contents of both sorbic and benzoic acid in 50 beverage samples did not exceed the residue allowance standards set by the Ministry of Food and Drug Safety (MFDS). Sulfur dioxide was detected in 12 beverages samples, but its content was lower than the detection limit specified in the method by the Korea Food Code. On the other hand, sorbic acid was not detected all samples. These results provide a basic data regarding sorbic acid, benzoic acid and sulfur dioxide in commonly consumed beverages, snacks and instant ramens in Korea.
문효,hanxionggao,오건,임지현,임준석,조근희,최선일,이옥환 한국식품과학회 2024 Food Science and Biotechnology Vol.33 No.3
Sulforaphane (SFN) is an isothiocyanate commonly found in cruciferous vegetables. It is formed via the enzymatic hydrolysis of glucoraphanin by myrosinase. SFN exerts various biological effects, including anti-cancer, anti-oxidation, anti-obesity, and anti-inflammatory effects, and is widely used in functional foods and clinical medicine. However, the structure of SFN is unstable and easily degradable, and its production is easily affected by temperature, pH, and enzyme activity, which limit its application. Hence, several studies are investigating its physicochemical properties, stability, and biological activity to identify methods to increase its content. This article provides a comprehensive review of the plant sources, extraction and analysis techniques, in vitro and in vivo biological activities, and bioavailability of SFN. This article highlights the importance and provides a reference for the research and application of SFN in the future.
Physicochemical, nutritional and functional properties of Cucurbita moschata
문효,최선일,hanxionggao,권희연,장길웅,최예은,박성민,이옥환 한국식품과학회 2021 Food Science and Biotechnology Vol.30 No.2
Cucurbita moschata is widely planted in mostparts of the world, and is rich in carotenoids, vitamins,dietary fiber, minerals, and phenolic compounds. It also hasimportant medicinal value. Some related research hasproven that Cucurbita moschata has the potential ability toinduce anti-obesity, anti-diabetic, antibacterial, and anticancereffects. At the same time, it has attracted moreattention in the medical field. These nutrients and bioactivecompounds in Cucurbita moschata have important effectson human health. In order to make better use of this crop, itstill needs further study. Therefore, the purpose of thisarticle is to summarize the physicochemical properties andnutritional components of Cucurbita moschata, and toprovide a reference for further research on the benefits ofon human health.