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      • KCI등재

        Numerical solution for multiple confocal elliptic dissimilar cylinders

        Y. Z. Chen 국제구조공학회 2017 Smart Structures and Systems, An International Jou Vol.19 No.2

        This paper provides a numerical solution for multiple confocal elliptic dissimilar cylinders. In the problem, the inner elliptic notch is under the traction free condition. The medium is composed of many confocal elliptic dissimilar cylinders. The transfer matrix method is used to study the continuity condition for the stress and displacement along the interfaces. Two cases, or the infinite matrix case and the finite matrix case, are studied in this paper. In the former case, the remote tension is applied in y- direction. In the latter case, the normal loading is applied along the exterior elliptic contour. For two cases, several numerical results are provided.

      • KCI등재

        R&D Status of High-current Accelerators at IFP

        J. J. Deng,J. S. Shi,W. P. Xie,L. W. Zhang,K. Z. Zhang,S. P. Feng,J. Li,M. Wang,Y. He,L. S. Xia,Z. Y. Dai,H. T. Li,L. Wen,S. F. Chen,X. Li,Q. G. Lai,M. H. Xia,Y. C. Guan,S. Y. Song,L. Chen 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.61

        High-current accelerators have many important applications in Z-pinches, high-power microwaves, and free electron lasers, imploding liners and radiography and so on. Research activities on Zpinches, imploding liners, radiography at the Institute of Fluid Physics (IFP) are introduced. Several main high-current accelerators developed and being developed at IFP are described, such as the Linear Induction Accelerator X-Ray Facility Upgrade (LIAXFU, 12 MeV, 2.5 kA, 90 ns), the Dragon-I linear induction accelerator (20 MeV, 2.5 kA, 60 ns), and the Primary Test Stand for Z-pinch (PTS, 10 MA, 120 ns). The design of Dragon-II linear induction accelerator (20 MeV, 2.5 kA, 3 × 60 ns) to be built will be presented briefly.

      • A Phase 3 Evaluation of Daclatasvir plus Asunaprevir in Treatment-Naive Patients with Chronic HCV Genotype 1b Infection

        ( L. Wei ),( F. Wang ),( M. Zhang ),( J. Jia ),( A.A. Yakovlev ),( W. Xie ),( E.Z. Burnevich ),( J. Niu ),( Y.J. Jung ),( X. Jiang ),( M. Xu ),( X. Chen ),( Q. Xie ),( J. Li ),( J. Hou ),( H. Tang ),( 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

        Background/Aims: Treatment-naive GT 1b-infected patients from mainland China, South Korea and Russia were assessed for SVR at follow-up week 12 (SVR12) after receiving daclatasvir (60 mg, QD) and asunaprevir (100 mg, BID) (DCV+ASV). Methods: Patients were randomized 3:1 to receive DCV+ASV (24 weeks; immediate treatment [IM]) or 12 weeks of placebo followed by DCV+ASV (24 weeks; placebo-deferred treatment [PD]). The primary endpoint was to evaluate SVR12 in the IM arm to the historical rate for peginterferon/ribavirin (70%). Secondary endpoints included overall safety and safety comparisons between the treatment arms during the first 12 weeks. Results: 207 patients were randomized to IM (n=155) or PD (n=52); Asian (86%), female (59%), IL28B CC genotype (68%) and median age 49 (range 18-73) years; cirrhosis (13%), HCV RNA ≥6x106 IU/mL (53%). SVR12 in the IM arm was 92% and broadly unaffected by most baseline factors assessed (Figure); SVR12 was higher in patients without (96%) baseline NS5A-L31M/V or Y93H polymorphisms. There were 6 virologic breakthroughs, 6 relapses and 1 detectable HCV RNA at end-of-treatment in the IM arm. Safety was mostly comparable between the two arms during the first 12 weeks. The most frequent adverse events (AEs; ≥5%) during DCV+ASV (24 weeks) treatment in both arms were aminotransferase, bilirubin and INR elevations, hypertension, fatigue and respiratory tract infections; the most frequent treatment-emergent grade 3/4 laboratory abnormalities were aminotransferase (≤4.5%) and hematologic, lipase and total bilirubin abnormalities (≤2%); one patient (IM) discontinued DCV+ASV for aminotransferase elevations, nausea and jaundice (all reversible); one patient PD) discontinued DCV+ASV for a fatal AE unrelated to treatment. Conclusions: These data demonstrate that DCV+ASV is a highly efficacious and well tolerated treatment for treatment-naive HCV GT 1b-infected patients. Those treated immediately with DCV+ASV achieved a 92% SVR12 rate which was unaffected by factors known to attenuate response to interferon.

      • SCIESCOPUSKCI등재

        True Digestibility of Phosphorus in Different Resources of Feed Ingredients in Growing Pigs

        Wu, X.,Ruan, Z.,Zhang, Y.G.,Hou, Y.Q.,Yin, Y.L.,Li, T.J.,Huang, R.L.,Chu, W.Y.,Kong, X.F.,Gao, B.,Chen, L.X. Asian Australasian Association of Animal Productio 2008 Animal Bioscience Vol.21 No.1

        To determine the true digestible phosphorus (TDP) requirement of growing pigs, two experiments were designed with the experimental diets containing five true digestible P levels (0.16%, 0.20%, 0.23%, 0.26% and 0.39%) and the ratio of total calcium to true digestible P (TDP) kept at 2:1. In Experiment 1, five barrows (Duroc${\times}$Landrace${\times}$Yorkshire) with an average initial body weight of 27.9 kg were used in a $5{\times}5$ Latin-square design to evaluate the effect of different dietary P levels on the digestibility and output of P and nitrogen. In Experiment 2, sixty healthy growing pigs (Duroc${\times}$Landrace${\times}$Yorkshire) with an average body weight (BW) of 21.4 kg were assigned randomly to one of the five dietary treatments (12 pigs/diet), and were used to determine the true digestible phosphorus (TDP) requirement of growing pigs on the basis of growth performance and serum biochemical indices. The results indicated that the true digestibility of P increased (p<0.05) linearly with increasing dietary TDP level below 0.26%. The true P digestibility was highest (56.6%) when dietary TDP was 0.34%. Expressed as g/kg dry matter intake (DMI), fecal P output increased (p<0.05) linearly with increasing P input. On the basis of g/kg fecal dry matter (DM), fecal P output was lowest for Diet 4 and highest (p<0.05) for Diet 5. The apparent digestibility of crude protein (CP) did not differ (p>0.05) among the five diets, with the average nitrogen output of 12.14 g/d and nitrogen retention of 66% to 74% (p>0.05), which suggested that there was no interaction between dietary P and CP protein levels. During the 28-d experimental period of Experiment 2, the average daily gain (ADG) of pigs was affected by dietary TDP levels as described by Eq. (1): $y=-809,532x^4+788,079x^3-276,250x^2+42,114x-1,759$; ($R^2=0.99$; p<0.01; y = ADG, g/d; x = dietary TDP, %), F/G for pigs by Eq. (2): $y=3,651.1x^4-3,480.4x^3+1,183.8x^2-172.5x+10.9$ ($R^2=0.99$; p<0.01; y = F/G; x = dietary TDP, %), and Total P concentrations in serum by Eq. (3): $y=-3,311.7x^4+3,342.7x^3-1,224.6x^2+195.6x-8.7$ (R2 = 0.99; p<0.01; y = total serum P concentration and x = dietary TDP, %). The highest ADG (782 g/d), the lowest F/G (1.07) and the highest total serum P concentration (3.1 mmol/L) were obtained when dietary TDP level was 0.34%. Collectively, these results indicate that the optimal TDP requirement of growing pigs is 0.34% of the diet at a total Ca to TDP ratio of 2:1.

      • KCI등재

        Effect of channel thickness on electrical performance of amorphous IGZO thin-film transistor with atomic layer deposited alumina oxide dielectric

        Y. Li,Y.L. Pei,R.Q. Hu,Z.M. Chen,Y. Zhao,Z. Shen,B.F. Fan,J. Liang,G.Wang 한국물리학회 2014 Current Applied Physics Vol.14 No.7

        We have investigated the electrical performance of amorphous indiumegalliumezinc oxide (a-IGZO) thin-film transistors with various channel thicknesses. It is observed that when the a-IGZO thickness increases, the threshold voltage decreases as reported at other researches. The intrinsic field-effect mobility as high as 11.1 cm2/Vs and sub threshold slope as low as w0.2 V/decade are independent on the thickness of a-IGZO channel, which indicate the excellent interface between a-IGZO and atomic layer deposited Al2O3 dielectric even for the case with a-IGZO thickness as thin as 10 nm. However, the source and drain series resistances increased with increasing of a-IGZO channel thickness, which results in the apparent field-effect mobility decreasing. The threshold voltage shift (DVth) under negative bias stress (NBS) and negative bias illumination stress (NBIS) were investigated, also. The hump-effect in the sub threshold region under NBS and threshold voltage shift to negative position under NBIS were enhanced with decreasing of a-IGZO channel thickness, owing to the enhancement of vertical electrical field in channel.

      • KCI등재

        Solution of periodic notch problems in an infinite plate using BIE in conjunction with remainder estimation technique

        Y.Z. Chen 국제구조공학회 2011 Structural Engineering and Mechanics, An Int'l Jou Vol.38 No.5

        This paper provides a complex variable BIE for solving the periodic notch problems in plane plasticity. There is no limitation for the configuration of notches. For the periodic notch problem, the remainder estimation technique is suggested. In the technique, the influences on the central notch from many neighboring notches are evaluated exactly. The influences on the central notch from many remote notches are approximated by one term with a multiplying factor. This technique provides an effective way to solve the problems of periodic structures. Several numerical examples are presented, and most of them have not been reported previously.

      • KCI등재

        A numerical solution for a finite internally cracked plate using hybrid crack element method

        Y.Z. Chen 국제구조공학회 2011 Structural Engineering and Mechanics, An Int'l Jou Vol.40 No.6

        This paper provides a numerical solution for a finite internally cracked plate using hybrid crack element method (HCE). In the formulation, an inclined crack is placed in any place of a rectangular element and the complex variable method is used. The complex potentials are expressed in a series form, and several undetermined coefficients are involved. The complex potentials for the cracked rectangle are first suggested in this paper. Based on a variational principle, the element stiffness matrix can be evaluated. The next steps are same as in the usual finite element method. Several numerical examples with computed stress intensity factor and T-stress are presented.

      • KCI등재

        Properties of integral operators in complex variable boundary integral equation in plane elasticity

        Y.Z. Chen,Z.X. Wang 국제구조공학회 2013 Structural Engineering and Mechanics, An Int'l Jou Vol.45 No.4

        This paper investigates properties of integral operators in complex variable boundary integral equation in plane elasticity, which is derived from the Somigliana identity in the complex variable form. The generalized Sokhotski-Plemelj’s formulae are used to obtain the BIE in complex variable. The properties of some integral operators in the interior problem are studied in detail. The Neumann and Dirichlet problems are analyzed. The prior condition for solution is studied. The solvability of the formulated problems is addressed. Similar analysis is carried out for the exterior problem. It is found that the properties of some integral operators in the exterior boundary value problem (BVP) are quite different from their counterparts in the interior BVP.

      • KCI등재

        Some general properties in the degenerate scale problem of antiplane elasticity or Laplace equation

        Y. Z. Chen 국제구조공학회 2017 Structural Engineering and Mechanics, An Int'l Jou Vol.64 No.6

        This paper investigates some general properties in the degenerate scale problem of antiplane elasticity or Laplace equation. For a given configuration, the degenerate scale problem is solved by using conformal mapping technique, or by using the null field BIE (boundary integral equation) numerically. After solving the problem, we can define and evaluate the degenerate area which is defined by the area enclosed by the contour in the degenerate configuration. It is found that the degenerate area is an important parameter in the problem. After using the conformal mapping, the degenerate area can be easily evaluated. The degenerate area for many configurations, from triangle, quadrilles and N-gon configuration are evaluated numerically. Most properties studied can only be found by numerical computation. The investigated properties provide a deeper understanding for the degenerate scale problem.

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