http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Up-dating of new dCAPS markers for mapping yield-related traits using MGRIL
Ye-Ji Lee,Hyun-Ju Lee,In-Seon Jeong,Seon-Hwa Bae,Hyeon-So Ji,Gang-Seob Lee,Ung-Han Yoon,Jang-Ho Hahn,Tae-Ho Kim 한국육종학회 2015 한국육종학회 심포지엄 Vol.2015 No.07
The next-generation sequencing(NGS) technology is being used for more effective genetic mapping. In previous study, we obtained 60x coverage of sequence from Milyang23 and Gihobyeo on average comparing with Nipponbare reference genome. Also, we developed new derived cleaved amplified polymorphic sequence(dCAPS) markers based on the single nucleotide polymorphisms(SNPs) in coding region sequence(CDS) between these varieties. Totally, 1,726,798 SNPs between Milyang23 and Gihobyeo were detected. Among them, 146 SNP were selected for making dCAPS markers and located on genetic map with previously reported 219 PCR-based DNA markers. The map was applied to the detection of quantitative trait loci(QTLs) for stem internode diameters, culm length and panicle length within MGRIL population, and six QTLs with relatively high LOD score were found at three chromosomes; culm length and stem diameter including the first internode diameter, third and fourth internode diameter. This study showed that the NGS allowed the rapid discovery of a large number of SNPs for dCAPS marker. So, we tried to find out more single nucleotide polymorphisms(SNPs) which were located on the whole genome sequence, such as un-translated region(UTR), intron, Inter-region and coding region sequence(CDS) between Milyang23 and Gihobyeo varieties. And we collected phenotypic information about culm length, panicle length, four stem internode diameters and panicle number in rice MGRIL population for QTLs. Furthermore, results of QTL analysis described above will shows relevance of molecular markers in mapping genes for useful breeding.
ADI Analysis of Toxicity Report on 141 Bactericides including Anilazine
Ye Ji Bae,Jong Su Byun,Ki Hoon Kim,Min Jeong Lee,Do Hoon Kim,Ji Soo Seo,Seung-Woo Lee,Sung-Hee Choi,Ok-Nam Bae,Jin Seok Kang,Beom Seok Han 한국농약과학회 2021 한국농약과학회 학술발표대회 논문집 Vol.2021 No.11
This study analyzed the Acceptable Daily Intake (ADI) level for the toxicity assessment report on 141 bactericides, including registered in domestic country. NOAEL and ADI of bactericides toxicity study evaluated at domestic and foreign institute, toxicity study type based ADI setting, grade of ADI level, major toxicity and target organ were analyzed. As a result, agencies the most reporting bactericides toxicity data is the Food Safety Commission in Japan (FSC, 36%). Other government agencies are EFSA, EPA, JMPR, INCHEM and other apparatuses in that order. When setting different ADI level to one substance, the cause of the ADI difference among institution was the type of the toxicity test, modification of significant figures and safety factor in that order. As for major toxicity study affecting ADI setting, the chronic toxicity was the highest (25%, 35/141). Other toxicities were chronic/carcinogenicity combined test, repeated dose toxicity test, carcinogenicity test, reproductive and developmental toxicity in that order. As for the classification of ADI grade, a number of ADI range was usually confirmed in the between 0.01 mg/kg bw/day and 0.1 mg/kg bw/day (59%, 83/141). The major target organ affecting ADI setting was the liver (hypertrophy, fatty change, etc.). After that, the kidney (pigmentation, etc.) and thyroid (hypertrophy, etc.) were listed in that order, and other organs were selected as target organs. Therefore, the toxicity report analysis of 141 bactericides will contribute to obtain reliable safety data and evaluate accurate risk assessment of pesticide.
NGS 기반 밀양23호/기호벼 재조합자식 유전집단(MGRIL)을 이용한 CAPS 마커 개발 및 줄기 굵기 형질 관련 QTL 분석
이예지(Ye-Ji Lee),변은주(Eun-Ju Byeon),배선화(Seon-Hwa Bae),지현소(Hyeonso Ji),이강섭(Gang-Seob Lee),윤웅한(Ung-Han Yoon),김태호(Tae-Ho Kim) 한국육종학회 2016 한국육종학회지 Vol.48 No.3
The rice recombinant inbred lines derived from Milyang23 and Gihobyeo cross were used in genetic mapping and QTL analysis studies. In this study, we developed a new 101 CAPS markers based on the SNPs in the whole genome region between these varieties. As a result, the total genetic distance and average distances were 1,696.97 cM and 3.64 cM, respectively. In comparison to the distance of the previous genetic map constructed based on 365 DNA markers, the new genetic map was found to have a decreased distance. The map was applied for the detection of QTLs on all seven traits relevant to diameter of stem internode, length of culms, length of panicles and the number of panicles including the correlation analysis between each trait. The QTLs results were similar to the report in previous studies, whereas the distance between the markers was narrowed and accuracy increased with the addition of 101 CAPS markers. A total of 9 new QTLs were detected for stem internode traits. Among them, qI1D-6 had higher LOD of 5.1 and phenotype variation of 50.92%. In this experiment, a molecular map was constructed with CAPS markers using next generation sequencing showing high accuracy for markers and QTLs. In the future, developing more accurate QTL information on stem internode diameters with various agriculturally important traits will be possible for further rice breeding.
난치성 SAPHO 증후군에서 Etanercept으로 치료한 1예
김예지 ( Ye Ji Kim ),배송이 ( Song I Bae ),최성재 ( Sung Jae Choi ),이영호 ( Young Ho Lee ),지종대 ( Jong Dae Ji ),송관규 ( Gwan Gyu Song ) 대한류마티스학회 2012 대한류마티스학회지 Vol.19 No.1
SAPHO syndrome, which has different skin changes and osteoarticular inflammation, is an acronym that stands for synovitis, acne, pustulosis, hyperostosis, and osteitis. Treatment of SAPHO syndrome includes non-steroidal anti-inflammatory drugs (NSAIDs), anti-rheumatic drugs, such as colchicines, corticosteroids and bisphosphonates, and disease-modifying agents. However, the treatment of SAPHO syndrome is controversial because it is a new clinical entity with unclear etiopathogenesis and inadequate clinical studies. We report a case with refractory SAPHO syndrome, which was successfully treated with a tumor necrosis factor (TNF)-α blocker.
배지선 ( Ji-seon Bae ),오예림 ( Ye-rim Oh ),김채원 ( Chae-won Kim ),박지원 ( Ji-won Park ),홍진근 ( Jin-keun Hong ),윤형기 ( Hyung-ki Yoon ) 한국정보처리학회 2021 한국정보처리학회 학술대회논문집 Vol.28 No.2
흔히, 웹 플랫폼에서 검색했을 때, 게시글 마지막부분에 광고인지 여부를 판단 할 수 있는 관련 글들이 나타난다. 이 글들은 사용자의 판단력을 흐리게 할 수 있다고 판단되며 개선의 필요성이 제기된다. 따라서 본 논문에서는 사용자들에게 웹 게시글에서 나타나는 광고성 여부에 대해 신속한 판단이 가능하도록 하는 환경에 대한 연구를 하고자 한다. 본 논문에서는 게시글에 포함된 광고 관련 문구를 찾아 페이지 상단에 해당 정보를 제공하는 프로그램을 제작 게시함으로써, 광고여부를 판단할 수 있도록 하였다.
곽현지 ( Hyun Ji Kwak ),배나래 ( Na Rae Bae ),손소라 ( So Ra Son ),유예지 ( Ye Ji Yu ),차지은 ( Ji Eun Cha ),곽수경 ( Suk Yeong Gwag ),최상준 ( Sang Jun Choi ) 대구가톨릭대학교 자연과학연구소 2013 자연과학연구논문집 Vol.11 No.1
The purpose of this study is to evaluate the nail shop working conditions for the protection of the health of workers can be exposed to various concentrations of volatile organic compounds is to assess. The subjects of this study were the workers at nail shops registered with the Daegu Metropolitan Government. One place to the nail shop seven days of passive sampler was used to collect personal samples were collected during one working day, and the data was analyzed using GC/MS Volatile Organic Compounds in Acetone, MEK(Methyl ethyl ketone), Ethanol, n-butyl alcohol, IPA (Isopropyl alcohol), Ethyl acetate, n-butyl acetate, Toluene has been detected, All volatile organic compounds showed a concentration below the exposure level. Of these Acetone, IPA (Isopropyl alcohol), Ethyl acetate containing a lot of working with the product and the total average concentration Acetone 4.5(±4.4) ppm, IPA(Isopropyl alcohol) 1.3 (±1.5) ppm were detected. Day according to the frequency working and the results of evaluating the concentration in the air on Thursday and Saturday were the most treatment. Thursday and Saturday, the higher the frequency of operation of the Acetone and IPA mean concentration was higher than the other days of the week.
Kyung-Sun Bae(Kyung-Sun Bae),Ji-Ye Kim(Ji-Ye Kim),Je-Yong Yoon(Je-Yong Yoon),Gwy-Am Shin(Gwy-Am Shin) 적정기술학회 2023 적정기술학회지(Journal of Appropriate Technology) Vol.9 No.3
Despite tremendous efforts from various international agencies such as World Health Organization (WHO), waterborne diseases are a still major cause of morbidity and mortality in the world – with more than 1 billion incidences and more than 2 million deaths per year. As an effort to mitigate this global burden, we developed a water disinfection system using electrochemical mixed oxidants-generating system. This system is simple, inexpensive, and easy to use. In this study, we determined the effectiveness of the new water disinfection system against waterborne pathogens using Escherichia coli CN13, bacteriophage MS2 and Bacillus subtilis spores as bacterial, viral, and protozoa indicator organisms, respectively. The results of this study showed that the new water disinfection system is very effective against E. coli CN13 (~3 log10 inactivation within 3 minutes with 0.3 mg/L of free chlorine) and coliphage MS2 (> 4 log10 inactivation within 3 minutes with 0.5 mg/L of free chlorine) Although the inactivation of B. subtilis spores by the new disinfection system was somewhat slow (~0.5 log10 inactivation in 60 minutes with 10 mg/L of free chlorine), the result is similar to previous studies with free chlorine. Overall, the results of this study indicate that the new water disinfection system using an electrochemical mixed oxidants-generating system is easy to use, convenient to carry, and also very effective against most waterborne pathogens, so it could be a sustainable solution for providing safe drinking water to the people in developing countries.